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Licia Iacoviello

Biographic Data

ID5465006
NAMELicia Iacoviello
GIVEN NAMESLicia
FAMILY NAMEIacoviello
SIGNATUREIACOVIELLO L
AFFILIATIONSUniversity of Insubria
ORCID0000-0003-0514-5885
VERIFIEDYes
TOTAL WORKS25
TOTAL CITATIONS14
AUTHOR COUNT25
EDITOR COUNT0
FIRST PUBLICATION YEAR2013
LATEST PUBLICATION YEAR2025
H-INDEX2
  • Clinical and environmental factors, functional status, and multimorbidity—stratifying progression and prognosis of multimorbidity, frailty, and disability: The Age-It Research Program

    Open Access•Licia Iacoviello, Rosa Liperoti et al.•ARTICLE•The Journals of Gerontology…•2025•Cited by: 1

    Overcoming the traditional medical approach, focused on the diagnosis and treatment of single diseases, Spoke 3 should provide important original evidence to improve the management of older subjects with multimorbidity and frailty

  • Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

    Open Access•Nowell H Phelps, Rosie Singleton et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…

  • Economic hardship resulting from the late 2000s Great Recession and long-term changes in mental health: A prospective analysis from the Moli-sani study

    Open Access•Francesca Bracone, Augusto Di Castelnuovo et al.•ARTICLE•BMC Public Health•2024

    Economic hardship resulting from the Great Recession in late 2000s was associated with deterioration of mental health, as reflected by increased depression symptoms and reduced perceived mental health

  • Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: An analysis for the Global Burden of Disease Study 2019

    Open Access•Emma Nichols, Jaimie D Steinmetz et al.•ARTICLE•The Lancet Public Health•2022

    BACKGROUND: Given the projected trends in population ageing and population growth, the number of people with dementia is expected to increase. In addition, strong evidence has emerged supporting the importance of potentially modifiable risk factors for dementia. Characterising the distribution and magnitude of anticipated growth is crucial for public health planning and resource prioritisation. This study aimed to improve on previous forecasts of…

  • Role of leukocytes, gender, and symptom domains in the influence of depression on hospitalization and mortality risk: Findings from the Moli-sani study

    Open Access•Alessandro Gialluisi, Francesca Bracone et al.•ARTICLE•Frontiers in Psychiatry•2022

    These findings highlight the importance of cellular components of inflammation, gender, and somatic depressive symptoms in the link between depression and clinical (especially CVD) risks, pointing to the existence of additional pathways through which depression may play a detrimental effect on the cardiovascular system

  • Older Adults’ Access to Care during the Covid-19 Pandemic: Results from the LOckdown and LifeSTyles (Lost) in Lombardia Project

    Open Access•Giacomo Pietro Vigezzi, Paola Bertuccio et al.•ARTICLE•International Journal of…•2022

    The COVID-19 pandemic disproportionally affected older people in terms of clinical outcomes and care provision. We aimed to investigate older adults' changes in access to care during the pandemic and their determinants. We used data from a cross-sectional study (LOST in Lombardia) conducted in autumn 2020 on a representative sample of 4400 older adults from the most populated region in Italy. Lifestyles, mental health, and access to healthcare se…

  • The North Italian Longitudinal Study Assessing the Mental Health Effects of Sars-CoV-2 Pandemic Health Care Workers—Part II: Structural Validity of Scales Assessing Mental Health

    Open Access•Emanuele Maria Giusti, Giovanni Veronesi et al.•ARTICLE•International Journal of…•2022

    It is unclear if the factor structure of the questionnaires that were employed by studies addressing the impact of COVID-19 on the mental health of Healthcare Workers (HCW) did not change due to the pandemic. The aim of this study is to assess the factor structure and longitudinal measurement invariance of the Maslach Burnout Inventory (MBI) and the factor structure of the General Health Questionnare-12 (GHQ-12), PTSD Checklist for DSM-5-Short Fo…

  • Clinical Network for Big Data and Personalized Health: Study Protocol and Preliminary Results

    Open Access•Simona Esposito, Sabatino Orlandi et al.•ARTICLE•International Journal of…•2022

    The use of secondary hospital-based clinical data and electronical health records (EHR) represent a cost-efficient alternative to investigate chronic conditions. We present the Clinical Network Big Data and Personalised Health project, which collects EHRs for patients accessing hospitals in Central-Southern Italy, through an integrated digital platform to create a digital hub for the collection, management and analysis of personal, clinical and e…

  • The North Italian Longitudinal Study Assessing the Mental Health Effects of Sars-CoV-2 Pandemic on Health Care Workers—Part I: Study Design and Psychometric Structural Validity of the HSE Indicator To…

    Open Access•Giovanni Veronesi, Emanuele Maria Giusti et al.•ARTICLE•International Journal of…•2022

    Literature on the impact of the SARS-CoV-2 pandemic on the mental health of Health Care Workers (HCWs) is mostly based on cross-sectional surveys. We designed a longitudinal study to assess work-related stress and mental health before and after the pandemic onset in a university-hospital in Lombardia region, Italy. We report on sample representativeness and structural validity of questionnaires assessing work stress (HSE Indicator Tool, HSE-IT) a…

  • Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: A pooled analysis of 1201 population-representative studies with 104 million participants

    Open Access•Bin Zhou, Rodrigo M Carrillo-Larco et al.•ARTICLE•The Lancet•2021

    BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…

  • Global, regional, and national burden of stroke and its risk factors, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019

    Open Access•Valery L Feigin, Benjamin A Stark et al.•ARTICLE•The Lancet Neurology•2021

    BACKGROUND: Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national leve…

  • Association of Psychological Resilience with All-Cause and Cardiovascular Mortality in a General Population in Italy: Prospective Findings from the Moli-Sani Study

    Open Access•Anwal Ghulam, Marialaura Bonaccio et al.•ARTICLE•International Journal of…•2021

    Psychological resilience (PR) is the capacity to adapt positively in face of adversity. Its role as an independent protective factor has been acknowledged in recent years. We aimed to test the association of PR with all-cause and cardiovascular disease (CVD) mortality in a general adult population. We performed longitudinal analyses on 10,406 CVD-free individuals from the Moli-Sani cohort (follow up = 11.2 year). PR was assessed by the 25-item Co…

  • Ultra-processed food consumption and its correlates among Italian children, adolescents and adults from the Italian Nutrition & Health Survey (Inhes) cohort study

    Open Access•Emilia Ruggiero, Simona Esposito et al.•ARTICLE•Public Health Nutrition•2021

    Objective: To assess ultra-processed food (UPF) consumption and its socio-demographic, psychosocial and behavioural correlates in a general population of Italian children, adolescents and adults. Design: Cross-sectional telephone-based survey Setting: Italy, 2010–2013. Participants: In total, 9078 participants (5–97 years) from the Italian Nutrition & Health Survey. Dietary intakes were collected by a 1-d 24-h dietary recall. UPF was defined by t…

  • Changes in ultra-processed food consumption during the first Italian lockdown following the Covid-19 pandemic and major correlates: Results from two population-based cohorts

    Open Access•Marialaura Bonaccio, Simona Costanzo et al.•ARTICLE•Public Health Nutrition•2021

    Objective: To evaluate changes in ultra-processed food (UPF) intake and its major correlates during the first Italian lockdown (9 March–3 May 2020). Design: Retrospective observational study. Setting: Italy. Participants: We analysed 2992 subjects (mean age 57·9 ± 15·3 years, 40·4 % men). Individual participant data were pooled from two retrospective cohorts: (1) The Moli-LOCK cohort consists of 1501 adults, a portion of the larger Moli-sani stud…

  • Roles of allostatic load, lifestyle and clinical risk factors in mediating the association between education and coronary heart disease risk in Europe

    Open Access•Blánaid Hicks, Giovanni Veronesi et al.•ARTICLE•Journal of Epidemiology and…•2021•References: 42

    BACKGROUND: Previous studies have shown that differential exposure to lifestyle factors may mediate the association between education and coronary heart diseases (CHD). However, few studies have examined the potential roles of allostatic load (AL) or differential susceptibility. METHODS: 25 310 men and 26 018 women aged 35-74 and CHD free at baseline were identified from 21 European cohorts and followed for a median of 10 years, to investigate th…

  • Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: A pooled analysis of 2181 population-based studies with 65 million p…

    Open Access•Andrea Rodriguez-Martinez, Andrea Rodriguez‐Martinez et al.•ARTICLE•The Lancet•2020

    BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …

  • Decomposing the educational gradient in allostatic load across European populations. What matters the most: Differentials in exposure or in susceptibility

    Giovanni Veronesi, Frank Kee et al.•ARTICLE•Journal of Epidemiology and…•2020•Cited by: 1•References: 38

    Background We investigate whether socially disadvantaged individuals are more susceptible to the detrimental effects of smoking and alcohol intake on allostatic load (AL), a marker of physiological ‘wear and tear’, resulting from adaptation to chronic stress. Methods In a cross-sectional analysis, 27 019 men and 26 738 women aged 35–74 years were identified from 21 European cohorts in the BiomarCaRE consortium. We defined three educational classe…

  • Rising rural body-mass index is the main driver of the global obesity epidemic in adults

    Open Access•NCD Risk Factor Collaboration, Honor Bixby et al.•ARTICLE•Nature•2019

    Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…

  • Association between variants of neuromedin U gene and taste thresholds and food preferences in European children: Results from the Idefics study

    Open Access•Claudio Grippi, Wolfgang Ahrens et al.•ARTICLE•Appetite•2019•References: 35

  • Socioeconomic trajectories across the life course and risk of total and cause-specific mortality: Prospective findings from the Moli-sani Study

    Marialaura Bonaccio, Augusto Di Castelnuovo et al.•ARTICLE•Journal of Epidemiology and…•2019•Cited by: 1•References: 36

    BACKGROUND: A life course approach has been suggested as the most appropriate to establish the total impact of socioeconomic status (SES) on adult health outcomes; however, such an approach has been poorly used within Mediterranean populations. We aimed to examine the SES trajectories from childhood to adulthood associated with mortality risk in a large general population-based cohort and to test potential pathways (eg, inflammation) underlying s…

  • Worldwide trends in blood pressure from 1975 to 2015: A pooled analysis of 1479 population-based measurement studies with 19·1 million participants

    Open Access•Bin Zhou, James Bentham et al.•ARTICLE•The Lancet•2017

    BACKGROUND: Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. METHODS: For this analysis, we pooled national, subnational, or comm…

  • Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and …

    Open Access•Leandra Abarca-Gómez, Ziad Abdeen et al.•ARTICLE•The Lancet•2017

    BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. METHODS: We pooled 2416 population-based studies with measurements of height…

  • Determinants of social inequalities in stroke incidence across Europe: A collaborative analysis of 126 635 individuals from 48 cohort studies

    Marco M Ferrario, Giovanni Veronesi et al.•ARTICLE•Journal of Epidemiology and…•2017•Cited by: 2•References: 27

    BACKGROUND: Knowledge on the origins of the social gradient in stroke incidence in different populations is limited. This study aims to estimate the burden of educational class inequalities in stroke incidence and to assess the contribution of risk factors in determining these inequalities across Europe. MATERIALS AND METHODS: The MORGAM (MOnica Risk, Genetics, Archiving and Monograph) Study comprises 48 cohorts recruited mostly in the 1980s and …

  • Using concept mapping in the development of the EU-PAD framework (EUropean-Physical Activity Determinants across the life course): A Dedipac-study

    Open Access•Giancarlo Condello, Fiona Chun Man Ling et al.•ARTICLE•BMC Public Health•2016

    The current framework provides a preliminary overview of factors which may account for PA behaviour across the life course and are most relevant to the European community. These insights could potentially be a foundation for future Pan-European research on how these factors might interact with each other, and assist policy makers to identify appropriate interventions to maximize PA behaviours and thus the health of European citizens

  • Nutrition knowledge is associated with higher adherence to Mediterranean diet and lower prevalence of obesity. Results from the Moli-sani study

    Open Access•Marialaura Bonaccio, Augusto Di Castelnuovo et al.•ARTICLE•Appetite•2013•Cited by: 9•References: 31

  • Nutrition knowledge is associated with higher adherence to Mediterranean diet and lower prevalence of obesity. Results from the Moli-sani study

    Open Access•Marialaura Bonaccio, Augusto Di Castelnuovo et al.•ARTICLE•Appetite•2013•Cited by: 9•References: 31

  • Determinants of social inequalities in stroke incidence across Europe: A collaborative analysis of 126 635 individuals from 48 cohort studies

    Marco M Ferrario, Giovanni Veronesi et al.•ARTICLE•Journal of Epidemiology and…•2017•Cited by: 2•References: 27

    BACKGROUND: Knowledge on the origins of the social gradient in stroke incidence in different populations is limited. This study aims to estimate the burden of educational class inequalities in stroke incidence and to assess the contribution of risk factors in determining these inequalities across Europe. MATERIALS AND METHODS: The MORGAM (MOnica Risk, Genetics, Archiving and Monograph) Study comprises 48 cohorts recruited mostly in the 1980s and …

  • Clinical and environmental factors, functional status, and multimorbidity—stratifying progression and prognosis of multimorbidity, frailty, and disability: The Age-It Research Program

    Open Access•Licia Iacoviello, Rosa Liperoti et al.•ARTICLE•The Journals of Gerontology…•2025•Cited by: 1

    Overcoming the traditional medical approach, focused on the diagnosis and treatment of single diseases, Spoke 3 should provide important original evidence to improve the management of older subjects with multimorbidity and frailty

  • Decomposing the educational gradient in allostatic load across European populations. What matters the most: Differentials in exposure or in susceptibility

    Giovanni Veronesi, Frank Kee et al.•ARTICLE•Journal of Epidemiology and…•2020•Cited by: 1•References: 38

    Background We investigate whether socially disadvantaged individuals are more susceptible to the detrimental effects of smoking and alcohol intake on allostatic load (AL), a marker of physiological ‘wear and tear’, resulting from adaptation to chronic stress. Methods In a cross-sectional analysis, 27 019 men and 26 738 women aged 35–74 years were identified from 21 European cohorts in the BiomarCaRE consortium. We defined three educational classe…

  • Socioeconomic trajectories across the life course and risk of total and cause-specific mortality: Prospective findings from the Moli-sani Study

    Marialaura Bonaccio, Augusto Di Castelnuovo et al.•ARTICLE•Journal of Epidemiology and…•2019•Cited by: 1•References: 36

    BACKGROUND: A life course approach has been suggested as the most appropriate to establish the total impact of socioeconomic status (SES) on adult health outcomes; however, such an approach has been poorly used within Mediterranean populations. We aimed to examine the SES trajectories from childhood to adulthood associated with mortality risk in a large general population-based cohort and to test potential pathways (eg, inflammation) underlying s…

  • Nutrition knowledge is associated with higher adherence to Mediterranean diet and lower prevalence of obesity. Results from the Moli-sani study

    Open Access•Marialaura Bonaccio, Augusto Di Castelnuovo et al.•ARTICLE•Appetite•2013•Cited by: 9•References: 31

  • Using concept mapping in the development of the EU-PAD framework (EUropean-Physical Activity Determinants across the life course): A Dedipac-study

    Open Access•Giancarlo Condello, Fiona Chun Man Ling et al.•ARTICLE•BMC Public Health•2016

    The current framework provides a preliminary overview of factors which may account for PA behaviour across the life course and are most relevant to the European community. These insights could potentially be a foundation for future Pan-European research on how these factors might interact with each other, and assist policy makers to identify appropriate interventions to maximize PA behaviours and thus the health of European citizens

  • Worldwide trends in blood pressure from 1975 to 2015: A pooled analysis of 1479 population-based measurement studies with 19·1 million participants

    Open Access•Bin Zhou, James Bentham et al.•ARTICLE•The Lancet•2017

    BACKGROUND: Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. METHODS: For this analysis, we pooled national, subnational, or comm…

  • Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and …

    Open Access•Leandra Abarca-Gómez, Ziad Abdeen et al.•ARTICLE•The Lancet•2017

    BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. METHODS: We pooled 2416 population-based studies with measurements of height…

  • Determinants of social inequalities in stroke incidence across Europe: A collaborative analysis of 126 635 individuals from 48 cohort studies

    Marco M Ferrario, Giovanni Veronesi et al.•ARTICLE•Journal of Epidemiology and…•2017•Cited by: 2•References: 27

    BACKGROUND: Knowledge on the origins of the social gradient in stroke incidence in different populations is limited. This study aims to estimate the burden of educational class inequalities in stroke incidence and to assess the contribution of risk factors in determining these inequalities across Europe. MATERIALS AND METHODS: The MORGAM (MOnica Risk, Genetics, Archiving and Monograph) Study comprises 48 cohorts recruited mostly in the 1980s and …

  • Rising rural body-mass index is the main driver of the global obesity epidemic in adults

    Open Access•NCD Risk Factor Collaboration, Honor Bixby et al.•ARTICLE•Nature•2019

    Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…

  • Association between variants of neuromedin U gene and taste thresholds and food preferences in European children: Results from the Idefics study

    Open Access•Claudio Grippi, Wolfgang Ahrens et al.•ARTICLE•Appetite•2019•References: 35

  • Socioeconomic trajectories across the life course and risk of total and cause-specific mortality: Prospective findings from the Moli-sani Study

    Marialaura Bonaccio, Augusto Di Castelnuovo et al.•ARTICLE•Journal of Epidemiology and…•2019•Cited by: 1•References: 36

    BACKGROUND: A life course approach has been suggested as the most appropriate to establish the total impact of socioeconomic status (SES) on adult health outcomes; however, such an approach has been poorly used within Mediterranean populations. We aimed to examine the SES trajectories from childhood to adulthood associated with mortality risk in a large general population-based cohort and to test potential pathways (eg, inflammation) underlying s…

  • Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: A pooled analysis of 2181 population-based studies with 65 million p…

    Open Access•Andrea Rodriguez-Martinez, Andrea Rodriguez‐Martinez et al.•ARTICLE•The Lancet•2020

    BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …

  • Decomposing the educational gradient in allostatic load across European populations. What matters the most: Differentials in exposure or in susceptibility

    Giovanni Veronesi, Frank Kee et al.•ARTICLE•Journal of Epidemiology and…•2020•Cited by: 1•References: 38

    Background We investigate whether socially disadvantaged individuals are more susceptible to the detrimental effects of smoking and alcohol intake on allostatic load (AL), a marker of physiological ‘wear and tear’, resulting from adaptation to chronic stress. Methods In a cross-sectional analysis, 27 019 men and 26 738 women aged 35–74 years were identified from 21 European cohorts in the BiomarCaRE consortium. We defined three educational classe…

  • Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: A pooled analysis of 1201 population-representative studies with 104 million participants

    Open Access•Bin Zhou, Rodrigo M Carrillo-Larco et al.•ARTICLE•The Lancet•2021

    BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…

  • Global, regional, and national burden of stroke and its risk factors, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019

    Open Access•Valery L Feigin, Benjamin A Stark et al.•ARTICLE•The Lancet Neurology•2021

    BACKGROUND: Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national leve…

  • Association of Psychological Resilience with All-Cause and Cardiovascular Mortality in a General Population in Italy: Prospective Findings from the Moli-Sani Study

    Open Access•Anwal Ghulam, Marialaura Bonaccio et al.•ARTICLE•International Journal of…•2021

    Psychological resilience (PR) is the capacity to adapt positively in face of adversity. Its role as an independent protective factor has been acknowledged in recent years. We aimed to test the association of PR with all-cause and cardiovascular disease (CVD) mortality in a general adult population. We performed longitudinal analyses on 10,406 CVD-free individuals from the Moli-Sani cohort (follow up = 11.2 year). PR was assessed by the 25-item Co…

  • Ultra-processed food consumption and its correlates among Italian children, adolescents and adults from the Italian Nutrition & Health Survey (Inhes) cohort study

    Open Access•Emilia Ruggiero, Simona Esposito et al.•ARTICLE•Public Health Nutrition•2021

    Objective: To assess ultra-processed food (UPF) consumption and its socio-demographic, psychosocial and behavioural correlates in a general population of Italian children, adolescents and adults. Design: Cross-sectional telephone-based survey Setting: Italy, 2010–2013. Participants: In total, 9078 participants (5–97 years) from the Italian Nutrition & Health Survey. Dietary intakes were collected by a 1-d 24-h dietary recall. UPF was defined by t…

  • Changes in ultra-processed food consumption during the first Italian lockdown following the Covid-19 pandemic and major correlates: Results from two population-based cohorts

    Open Access•Marialaura Bonaccio, Simona Costanzo et al.•ARTICLE•Public Health Nutrition•2021

    Objective: To evaluate changes in ultra-processed food (UPF) intake and its major correlates during the first Italian lockdown (9 March–3 May 2020). Design: Retrospective observational study. Setting: Italy. Participants: We analysed 2992 subjects (mean age 57·9 ± 15·3 years, 40·4 % men). Individual participant data were pooled from two retrospective cohorts: (1) The Moli-LOCK cohort consists of 1501 adults, a portion of the larger Moli-sani stud…

  • Roles of allostatic load, lifestyle and clinical risk factors in mediating the association between education and coronary heart disease risk in Europe

    Open Access•Blánaid Hicks, Giovanni Veronesi et al.•ARTICLE•Journal of Epidemiology and…•2021•References: 42

    BACKGROUND: Previous studies have shown that differential exposure to lifestyle factors may mediate the association between education and coronary heart diseases (CHD). However, few studies have examined the potential roles of allostatic load (AL) or differential susceptibility. METHODS: 25 310 men and 26 018 women aged 35-74 and CHD free at baseline were identified from 21 European cohorts and followed for a median of 10 years, to investigate th…

  • Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: An analysis for the Global Burden of Disease Study 2019

    Open Access•Emma Nichols, Jaimie D Steinmetz et al.•ARTICLE•The Lancet Public Health•2022

    BACKGROUND: Given the projected trends in population ageing and population growth, the number of people with dementia is expected to increase. In addition, strong evidence has emerged supporting the importance of potentially modifiable risk factors for dementia. Characterising the distribution and magnitude of anticipated growth is crucial for public health planning and resource prioritisation. This study aimed to improve on previous forecasts of…

  • Role of leukocytes, gender, and symptom domains in the influence of depression on hospitalization and mortality risk: Findings from the Moli-sani study

    Open Access•Alessandro Gialluisi, Francesca Bracone et al.•ARTICLE•Frontiers in Psychiatry•2022

    These findings highlight the importance of cellular components of inflammation, gender, and somatic depressive symptoms in the link between depression and clinical (especially CVD) risks, pointing to the existence of additional pathways through which depression may play a detrimental effect on the cardiovascular system

  • Older Adults’ Access to Care during the Covid-19 Pandemic: Results from the LOckdown and LifeSTyles (Lost) in Lombardia Project

    Open Access•Giacomo Pietro Vigezzi, Paola Bertuccio et al.•ARTICLE•International Journal of…•2022

    The COVID-19 pandemic disproportionally affected older people in terms of clinical outcomes and care provision. We aimed to investigate older adults' changes in access to care during the pandemic and their determinants. We used data from a cross-sectional study (LOST in Lombardia) conducted in autumn 2020 on a representative sample of 4400 older adults from the most populated region in Italy. Lifestyles, mental health, and access to healthcare se…

  • The North Italian Longitudinal Study Assessing the Mental Health Effects of Sars-CoV-2 Pandemic Health Care Workers—Part II: Structural Validity of Scales Assessing Mental Health

    Open Access•Emanuele Maria Giusti, Giovanni Veronesi et al.•ARTICLE•International Journal of…•2022

    It is unclear if the factor structure of the questionnaires that were employed by studies addressing the impact of COVID-19 on the mental health of Healthcare Workers (HCW) did not change due to the pandemic. The aim of this study is to assess the factor structure and longitudinal measurement invariance of the Maslach Burnout Inventory (MBI) and the factor structure of the General Health Questionnare-12 (GHQ-12), PTSD Checklist for DSM-5-Short Fo…

  • Clinical Network for Big Data and Personalized Health: Study Protocol and Preliminary Results

    Open Access•Simona Esposito, Sabatino Orlandi et al.•ARTICLE•International Journal of…•2022

    The use of secondary hospital-based clinical data and electronical health records (EHR) represent a cost-efficient alternative to investigate chronic conditions. We present the Clinical Network Big Data and Personalised Health project, which collects EHRs for patients accessing hospitals in Central-Southern Italy, through an integrated digital platform to create a digital hub for the collection, management and analysis of personal, clinical and e…

  • The North Italian Longitudinal Study Assessing the Mental Health Effects of Sars-CoV-2 Pandemic on Health Care Workers—Part I: Study Design and Psychometric Structural Validity of the HSE Indicator To…

    Open Access•Giovanni Veronesi, Emanuele Maria Giusti et al.•ARTICLE•International Journal of…•2022

    Literature on the impact of the SARS-CoV-2 pandemic on the mental health of Health Care Workers (HCWs) is mostly based on cross-sectional surveys. We designed a longitudinal study to assess work-related stress and mental health before and after the pandemic onset in a university-hospital in Lombardia region, Italy. We report on sample representativeness and structural validity of questionnaires assessing work stress (HSE Indicator Tool, HSE-IT) a…

  • Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

    Open Access•Nowell H Phelps, Rosie Singleton et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…

  • Economic hardship resulting from the late 2000s Great Recession and long-term changes in mental health: A prospective analysis from the Moli-sani study

    Open Access•Francesca Bracone, Augusto Di Castelnuovo et al.•ARTICLE•BMC Public Health•2024

    Economic hardship resulting from the Great Recession in late 2000s was associated with deterioration of mental health, as reflected by increased depression symptoms and reduced perceived mental health

  • Clinical and environmental factors, functional status, and multimorbidity—stratifying progression and prognosis of multimorbidity, frailty, and disability: The Age-It Research Program

    Open Access•Licia Iacoviello, Rosa Liperoti et al.•ARTICLE•The Journals of Gerontology…•2025•Cited by: 1

    Overcoming the traditional medical approach, focused on the diagnosis and treatment of single diseases, Spoke 3 should provide important original evidence to improve the management of older subjects with multimorbidity and frailty

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