Mathuram Santosham

Dados Biográficos

ID5468689
NOMEMathuram Santosham
PRENOMESMathuram
SOBRENOMESantosham
ASSINATURASANTOSHAM M
AFILIAÇÕESJohns Hopkins University
VERIFICADONão
TOTAL DE OBRAS19
TOTAL DE CITAÇÕES9
TOTAL COMO AUTOR19
TOTAL COMO EDITOR0
PRIMEIRO ANO DE PUBLICAÇÃO2008
ANO MAIS RECENTE DE PUBLICAÇÃO2025
ÍNDICE H2

  • Causes and risk factors for deaths in young infants in South Asia

    Open AccessGary L Darmstadt, Salwa Abdalla et al.ARTICLEBMJ Global Health2025

    INTRODUCTION: Strategies for reducing infant mortality require accurate, local, population-level data. We conducted a population-based observational study in three countries in South Asia to describe risk factors, causes and rates of mortality in young infants. METHODS: Pregnancies, births and pregnancy outcomes were determined through household surveillance, and cause of deaths was ascertained by verbal autopsy. Cox regression was used to identi…

  • Development and validation of a novel clinical risk score to predict hypoxaemia in children with pneumonia using the WHO PREPARE dataset

    Open AccessRainer Tan, Arjun Chandna et al.ARTICLEBMJ Global Health2025

    BACKGROUND: Hypoxaemia predicts mortality at all levels of care, and appropriate management can reduce preventable deaths. However, pulse oximetry and oxygen therapy remain inaccessible in many primary care health facilities. We aimed to develop and validate a simple risk score comprising commonly evaluated clinical features to predict hypoxaemia in 2-59-month-old children with pneumonia. METHODS: Data from seven studies conducted in five countri…

  • Communication lessons learned from the 2017 measles–rubella campaign in India

    Open AccessRupali J Limaye, Madhu Gupta et al.ARTICLEHealth Promotion International2022

    In 2017, to reduce the burden of measles and rubella, a nation-wide measles–rubella campaign was launched in India. Despite detailed planning efforts that involved many stakeholders, vaccine refusal arose in several communities during the campaign. As strategic health communication and promotion is critical in any vaccine campaign, we sought to document lessons learned from the 2017 MR campaign from a strategic health communication and promotion …

  • Derivation and validation of a novel risk assessment tool to identify children aged 2–59 months at risk of hospitalised pneumonia-related mortality in 20 countries

    Open AccessChris A Rees, Trevor Colbourn et al.ARTICLEBMJ Global Health2022

    INTRODUCTION: Existing risk assessment tools to identify children at risk of hospitalised pneumonia-related mortality have shown suboptimal discriminatory value during external validation. Our objective was to derive and validate a novel risk assessment tool to identify children aged 2-59 months at risk of hospitalised pneumonia-related mortality across various settings. METHODS: We used primary, baseline, patient-level data from 11 studies, incl…

  • Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm

    Open AccessHelena Martin, H Martı́n et al.ARTICLEJournal of Global Health2022

    Background: The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to 5 years old. We aimed to collate an individual patient-level data set from large, high-quality pre-existing studies on pneumonia in children to identify a set of signs and symptoms with greater validity in the diagnosis, prognosis, and possible trea…

  • External validation of the Risc, Risc-Malawi, and PERCH clinical prediction rules to identify risk of death in children hospitalized with pneumonia

    Open AccessChris A Rees, Shubhada Hooli et al.ARTICLEJournal of Global Health2021

    BACKGROUND: Existing scores to identify children at risk of hospitalized pneumonia-related mortality lack broad external validation. Our objective was to externally validate three such risk scores. METHODS: We applied the Respiratory Index of Severity in Children (RISC) for HIV-negative children, the RISC-Malawi, and the Pneumonia Etiology Research for Child Health (PERCH) scores to hospitalized children in the Pneumonia REsearch Partnerships to …

  • Validation of community health worker identification of maternal puerperal sepsis using a clinical diagnostic algorithm in Bangladesh and Pakistan

    Open AccessAmnesty LeFevre, Amnesty E LeFevre et al.ARTICLEJournal of Global Health2021

    BACKGROUND: Puerperal sepsis (PP sepsis) is a leading cause of maternal mortality globally. The majority of maternal sepsis cases and deaths occur at home and remain undiagnosed and under-reported. In this paper, we present findings from a nested case-control study in Bangladesh and Pakistan which sought to assess the validity of community health worker (CHW) identification of PP sepsis using a clinical diagnostic algorithm with physician assessm…

  • Change in full immunization inequalities in Indian children 12–23 months

    Open AccessBrian Wahl, Madhu Gupta et al.ARTICLEBMC Public Health2021

    Immunization coverage and wealth-related equality have improved nationally and in most states over the last decade in India. Targeted, context-specific interventions could help address overall wealth-related full immunization inequalities. Intensified government efforts could help in this regard, particularly in high-focus states where child mortality remains high

  • Protecting children in low-income and middle-income countries from Covid-19

    Open AccessSalahuddin Ahmed, Tisungane Mvalo et al.ARTICLEBMJ Global Health2020

    A saving grace of the COVID-19 pandemic in high-income and upper middle-income countries has been the relative sparing of children. As the disease spreads across low-income and middle-income countries (LMICs), long-standing system vulnerabilities may tragically manifest, and we worry that children will be increasingly impacted, both directly and indirectly. Drawing on our shared child pneumonia experience globally, we highlight these potential im…

  • Elimination of diarrheal mortality in children – the last half million

    Open AccessMathuram Santosham, Christopher Duggan et al.ARTICLEJournal of Global Health2019

  • Global action plan for childhood diarrhoea

    Open AccessAlvin Zipursky, Kerri Wazny et al.ARTICLEJournal of Global Health2013

    BACKGROUND: Childhood diarrhoea remains a major public health problem responsible for the deaths of approximately 800 000 children annually, worldwide. The present study was undertaken to further define research priorities for the prevention and treatment of diarrhoea in low and middle income countries. We used the Child Health and Nutrition Research Initiative (CHNRI) process for defining research priorities. This provided a transparent, systema…

  • Effect of knowledge of community health workers on essential newborn health care

    Open AccessP K Agrawal, Prabhat Agrawal et al.ARTICLEHealth Policy and Planning2012Citada por: 2Referências: 15

    BACKGROUND: This study explored the relationship between the knowledge of community health workers (CHWs)-anganwadi workers (AWWs) and auxiliary nurse midwives (ANMs)-and their antenatal home visit coverage and effectiveness of the visits, in terms of essential newborn health care practices at the household level in rural India. METHODS: We used data from 302 AWWs and 86 ANMs and data from recently delivered women (RDW) (n=13,023) who were reside…

  • Clean cord care practices and neonatal mortality

    Praween Agrawal, Praween K Agrawal et al.ARTICLEJournal of Epidemiology and…2012Referências: 19

    BACKGROUND: About a million newborns die each year in India, accounting for about a fourth of total global neonatal deaths. Infections are among the leading causes of neonatal mortality. Care practices immediately following delivery contribute to newborns' risk of infection and mortality. OBJECTIVES: This study examined the association between clean cord care practices and neonatal mortality in rural Uttar Pradesh, India. METHODS: The study used …

  • Household surveillance of severe neonatal illness by community health workers in Mirzapur, Bangladesh

    Open AccessGary L Darmstadt, Shams El Arifeen et al.ARTICLEHealth Policy and Planning2010Referências: 26

    BACKGROUND: Effective and scalable community-based strategies are needed for identification and management of serious neonatal illness. METHODS: As part of a community-based, cluster-randomized controlled trial of the impact of a package of maternal-neonatal health care, community health workers (CHWs) were trained to conduct household surveillance and to identify and refer sick newborns according to a clinical algorithm. Assessments of newborns …

  • Effect of community-based behaviour change management on neonatal mortality in Shivgarh, Uttar Pradesh, India

    Open AccessVishwajeet Kumar, Saroj Ranjan Mohanty et al.ARTICLEThe Lancet2008

  • Vaccination greatly reduces disease, disability, death and inequity worldwide

    Open AccessFE Andre, André Fe et al.ARTICLEBulletin of the World Health…2008

    In low-income countries, infectious diseases still account for a large proportion of deaths, highlighting health inequities largely caused by economic differences. Vaccination can cut health-care costs and reduce these inequities. Disease control, elimination or eradication can save billions of US dollars for communities and countries. Vaccines have lowered the incidence of hepatocellular carcinoma and will control cervical cancer. Travellers can…

  • Effect of community-based newborn-care intervention package implemented through two service-delivery strategies in Sylhet district, Bangladesh

    Open AccessAbdulla H Baqui, Abdullah H Baqui et al.ARTICLEThe Lancet2008

  • Differentials in neonatal mortality in two adjacent rural areas of Bangladesh

    Open AccessAbdulla H Baqui, Shams El Arifeen et al.ARTICLEGlobal Public Health2008

    A household survey, conducted in three rural sub-districts of northeastern Bangladesh, revealed a markedly lower neonatal mortality rate (NMR) in one sub-district compared to two adjacent sub-districts. This study examines the degree to which the differential in NMR can be explained by factors that could be improved by maternal and newborn health programmes, such as knowledge of danger signs and use of antenatal, delivery, and postnatal care. Use…

  • NGO facilitation of a government community-based maternal and neonatal health programme in rural India

    Open AccessAbdulla H Baqui, A M Rosecrans et al.ARTICLEHealth Policy and Planning2008Citada por: 7Referências: 34

    Socio-economic disparities in health have been well documented around the world. This study examines whether NGO facilitation of the government's community-based health programme improved the equity of maternal and newborn health in rural Uttar Pradesh, India. A quasi-experimental study design included one intervention district and one comparison district of rural Uttar Pradesh. A household survey conducted between January and June 2003 establish…