Chittaranjan S Yajnik
Biographic Data
| ID | 5471394 |
|---|---|
| NAME | Chittaranjan S Yajnik |
| GIVEN NAMES | Chittaranjan S |
| FAMILY NAME | Yajnik |
| SIGNATURE | YAJNIK C S |
| AFFILIATIONS | King Edward Memorial Hospital Research Centre |
| ORCID | 0000-0002-2911-2378 |
| VERIFIED | Yes |
| TOTAL WORKS | 14 |
| TOTAL CITATIONS | 6 |
| WORKS AS AUTHOR | 14 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2001 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Folate and global health umbrella review series, part 1
Background: Folate is essential for normal growth and in human health throughout the lifecycle. Clinical deficiency of folate impairs DNA synthesis and results in megaloblastic anaemia, while suboptimal folate status before and in early pregnancy results in an elevated risk of neural tube defects (NTD). The evidence on the association of folate status with other health outcomes is largely fragmented and understudied. We conducted a series of umbr…
Folate and global health umbrella review series, part 2
Background: Folate has been examined extensively in relation to carcinogenesis due to its role in one-carbon metabolism impacting the synthesis of DNA and RNA, methylation processes, and genomic integrity. Current evidence on the relationship between folate status and the risk of cancer is equivocal: low or deficient folate status may contribute to an increased risk of cancers, while high-dose folic acid supplementation may have adverse effects o…
Adolescent diet and physical activity in the context of economic, social and nutrition transition in rural Maharashtra, India
Objective: To explore the perceptions of adolescents and their caregivers on drivers of diet and physical activity in rural India in the context of ongoing economic, social and nutrition transition. Design: A qualitative study comprising eight focus group discussions (FGD) on factors affecting eating and physical activity patterns, perceptions of health and decision-making on food preparation. Setting: Villages approximately 40–60 km from the cit…
The double burden of malnutrition
Developmental origins of secondary school dropout in rural India and its differential consequences by sex
We developed a biosocial life-course conceptual approach to investigate maternal and household predictors of secondary school dropout, and to ascertain whether the consequences of dropout differ between girls and boys. We analysed longitudinal biomedical data on 648 mother-child dyads from rural Maharashtra, India. Both maternal (low education, early marriage age, shorter pregnancy duration) and household (low paternal education, low socio-econom…
Before the beginning
Growth and body composition of children aged 2–4 years after exposure to community mobilisation women’s groups in Bangladesh
BACKGROUND: Women's groups interventions in Bangladesh reduced neonatal deaths by 38% and improved hygienic delivery, newborn care practices and breast feeding. We explore the longer-term impact of exposure to women's groups during pregnancy on child growth at 2-4 years. METHODS: We performed a cross-sectional survey of child anthropometric measures (analysed as z-scores) among children born to women who had participated in the women's groups int…
Nations within a nation
BACKGROUND: 18% of the world's population lives in India, and many states of India have populations similar to those of large countries. Action to effectively improve population health in India requires availability of reliable and comprehensive state-level estimates of disease burden and risk factors over time. Such comprehensive estimates have not been available so far for all major diseases and risk factors. Thus, we aimed to estimate the dise…
Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations
Data from many high- and low- or middle-income countries have linked exposures during key developmental periods (in particular pregnancy and infancy) to later health and disease. Africa faces substantial challenges with persisting infectious disease and now burgeoning non-communicable disease.This paper opens the debate to the value of strengthening the developmental origins of health and disease (DOHaD) research focus in Africa to tackle critica…
Body size and body composition
BACKGROUND: Indian babies are characterised by the 'thin-fat phenotype' which comprises a 'muscle-thin but adipose' body composition compared with European babies. This body phenotype is of concern because it is associated with an increased risk of diabetes and cardiovascular disease. We examined whether the 'thin-fat phenotype' persists through early childhood, comparing Indian children with white Caucasians in the UK at birth, infancy and child…
Iodine status during pregnancy in India and related neonatal and infant outcomes
Objective To document iodine status in Indian pregnancies, associations with maternal diet and demographics, and offspring developmental measures. Design Longitudinal study following mothers through pregnancy and offspring up to 24 months. Setting Rural health-care centre (Vadu) and urban antenatal clinic (Pune) in the Maharashtra region of India. Subjects Pregnant mothers at 17 ( n 132) and 34 weeks’ ( n 151) gestation and their infants from bir…
Risk of childhood undernutrition related to small-for-gestational age and preterm birth in low- and middle-income countries
BACKGROUND: Low- and middle-income countries continue to experience a large burden of stunting; 148 million children were estimated to be stunted, around 30-40% of all children in 2011. In many of these countries, foetal growth restriction (FGR) is common, as is subsequent growth faltering in the first 2 years. Although there is agreement that stunting involves both prenatal and postnatal growth failure, the extent to which FGR contributes to stu…
Diabetes in Asia
CONTEXT: With increasing globalization and East-West exchanges, the increasing epidemic of type 2 diabetes in Asia has far-reaching public health and socioeconomic implications. OBJECTIVE: To review recent data in epidemiologic trends, risk factors, and complications of type 2 diabetes in Asia. EVIDENCE ACQUISITION: Search of MEDLINE using the term diabetes and other relevant keywords to identify meta-analyses, systematic reviews, large surveys, …
Intake of Micronutrient-Rich Foods in Rural Indian Mothers Is Associated with the Size of Their Babies at Birth
Developmental origins of secondary school dropout in rural India and its differential consequences by sex
We developed a biosocial life-course conceptual approach to investigate maternal and household predictors of secondary school dropout, and to ascertain whether the consequences of dropout differ between girls and boys. We analysed longitudinal biomedical data on 648 mother-child dyads from rural Maharashtra, India. Both maternal (low education, early marriage age, shorter pregnancy duration) and household (low paternal education, low socio-econom…
Body size and body composition
BACKGROUND: Indian babies are characterised by the 'thin-fat phenotype' which comprises a 'muscle-thin but adipose' body composition compared with European babies. This body phenotype is of concern because it is associated with an increased risk of diabetes and cardiovascular disease. We examined whether the 'thin-fat phenotype' persists through early childhood, comparing Indian children with white Caucasians in the UK at birth, infancy and child…
Intake of Micronutrient-Rich Foods in Rural Indian Mothers Is Associated with the Size of Their Babies at Birth
Diabetes in Asia
CONTEXT: With increasing globalization and East-West exchanges, the increasing epidemic of type 2 diabetes in Asia has far-reaching public health and socioeconomic implications. OBJECTIVE: To review recent data in epidemiologic trends, risk factors, and complications of type 2 diabetes in Asia. EVIDENCE ACQUISITION: Search of MEDLINE using the term diabetes and other relevant keywords to identify meta-analyses, systematic reviews, large surveys, …
Risk of childhood undernutrition related to small-for-gestational age and preterm birth in low- and middle-income countries
BACKGROUND: Low- and middle-income countries continue to experience a large burden of stunting; 148 million children were estimated to be stunted, around 30-40% of all children in 2011. In many of these countries, foetal growth restriction (FGR) is common, as is subsequent growth faltering in the first 2 years. Although there is agreement that stunting involves both prenatal and postnatal growth failure, the extent to which FGR contributes to stu…
Iodine status during pregnancy in India and related neonatal and infant outcomes
Objective To document iodine status in Indian pregnancies, associations with maternal diet and demographics, and offspring developmental measures. Design Longitudinal study following mothers through pregnancy and offspring up to 24 months. Setting Rural health-care centre (Vadu) and urban antenatal clinic (Pune) in the Maharashtra region of India. Subjects Pregnant mothers at 17 ( n 132) and 34 weeks’ ( n 151) gestation and their infants from bir…
Body size and body composition
BACKGROUND: Indian babies are characterised by the 'thin-fat phenotype' which comprises a 'muscle-thin but adipose' body composition compared with European babies. This body phenotype is of concern because it is associated with an increased risk of diabetes and cardiovascular disease. We examined whether the 'thin-fat phenotype' persists through early childhood, comparing Indian children with white Caucasians in the UK at birth, infancy and child…
Nations within a nation
BACKGROUND: 18% of the world's population lives in India, and many states of India have populations similar to those of large countries. Action to effectively improve population health in India requires availability of reliable and comprehensive state-level estimates of disease burden and risk factors over time. Such comprehensive estimates have not been available so far for all major diseases and risk factors. Thus, we aimed to estimate the dise…
Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations
Data from many high- and low- or middle-income countries have linked exposures during key developmental periods (in particular pregnancy and infancy) to later health and disease. Africa faces substantial challenges with persisting infectious disease and now burgeoning non-communicable disease.This paper opens the debate to the value of strengthening the developmental origins of health and disease (DOHaD) research focus in Africa to tackle critica…
Before the beginning
Growth and body composition of children aged 2–4 years after exposure to community mobilisation women’s groups in Bangladesh
BACKGROUND: Women's groups interventions in Bangladesh reduced neonatal deaths by 38% and improved hygienic delivery, newborn care practices and breast feeding. We explore the longer-term impact of exposure to women's groups during pregnancy on child growth at 2-4 years. METHODS: We performed a cross-sectional survey of child anthropometric measures (analysed as z-scores) among children born to women who had participated in the women's groups int…
Developmental origins of secondary school dropout in rural India and its differential consequences by sex
We developed a biosocial life-course conceptual approach to investigate maternal and household predictors of secondary school dropout, and to ascertain whether the consequences of dropout differ between girls and boys. We analysed longitudinal biomedical data on 648 mother-child dyads from rural Maharashtra, India. Both maternal (low education, early marriage age, shorter pregnancy duration) and household (low paternal education, low socio-econom…
The double burden of malnutrition
Adolescent diet and physical activity in the context of economic, social and nutrition transition in rural Maharashtra, India
Objective: To explore the perceptions of adolescents and their caregivers on drivers of diet and physical activity in rural India in the context of ongoing economic, social and nutrition transition. Design: A qualitative study comprising eight focus group discussions (FGD) on factors affecting eating and physical activity patterns, perceptions of health and decision-making on food preparation. Setting: Villages approximately 40–60 km from the cit…
Folate and global health umbrella review series, part 1
Background: Folate is essential for normal growth and in human health throughout the lifecycle. Clinical deficiency of folate impairs DNA synthesis and results in megaloblastic anaemia, while suboptimal folate status before and in early pregnancy results in an elevated risk of neural tube defects (NTD). The evidence on the association of folate status with other health outcomes is largely fragmented and understudied. We conducted a series of umbr…
Folate and global health umbrella review series, part 2
Background: Folate has been examined extensively in relation to carcinogenesis due to its role in one-carbon metabolism impacting the synthesis of DNA and RNA, methylation processes, and genomic integrity. Current evidence on the relationship between folate status and the risk of cancer is equivocal: low or deficient folate status may contribute to an increased risk of cancers, while high-dose folic acid supplementation may have adverse effects o…
Medicine (11 works) · Birth, Development, and Health (7 works) · Environmental health (7 works) · Child Nutrition and Water Access (6 works) · Pregnancy (6 works) · Obesity (5 works) · Psychology (5 works) · Developmental psychology (4 works) · Pediatrics (4 works) · Demography (3 works)