Janine F Felix
Biographic Data
| ID | 5472713 |
|---|---|
| NAME | Janine F Felix |
| GIVEN NAMES | Janine F |
| FAMILY NAME | Felix |
| SIGNATURE | FÉLIX J F |
| AFFILIATIONS | The Generation R Study Group, Erasmus MC University Medical Center Rotterdam Rotterdam The Netherlands |
| VERIFIED | No |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 6 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2020 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Longitudinal co‐development of mental and cardio‐metabolic health from childhood to young adulthood
BACKGROUND: Depressive symptoms and cardio-metabolic risk factors often co-occur. However, our understanding of the potential mechanisms and temporal dynamics underlying their co-development remains elusive. METHODS: This population-based cohort study examined bidirectional longitudinal associations between depressive symptoms and cardio-metabolic risk factors from age 10 to 25 years, using prospective data from the ALSPAC Study. Participants wit…
Childhood internalising symptoms at ages 3 and 6
BACKGROUND: Pre- and postpartum environments and genetic effects influence childhood internalising problems, which increase depression risk. DNA methylation (DNAm) may capture some of these effects. We therefore investigated associations between child blood DNAm and internalising problems. METHODS: We meta-analysed probe and region-level epigenome-wide association studies using data from 3 European birth cohorts (ALSPAC, MoBa, Generation R; analy…
Type of information source and healthcare avoidance
Social media use was associated with higher odds of healthcare avoidance as compared to not using social media, whereas use of traditional media was related to lower avoidance. We found suggestive evidence for a role of anxiety symptoms in these associations, which should be validated by future studies. These findings emphasise the importance of disseminating accessible, objective information across a variety of media platforms, where needed tail…
DNA methylation at birth and lateral ventricular volume in childhood
BACKGROUND: Lateral ventricular volume (LVV) enlargement has been repeatedly linked to schizophrenia; yet, what biological factors shape LVV during early development remain unclear. DNA methylation (DNAm), an essential process for neurodevelopment that is altered in schizophrenia, is a key molecular system of interest. METHODS: In this study, we conducted the first epigenome-wide association study of neonatal DNAm in cord blood with LVV in childh…
An epigenome-wide association study of child appetitive traits and DNA methylation
The etiology of childhood appetitive traits is poorly understood. Early-life epigenetic processes may be involved in the developmental programming of appetite regulation in childhood. One such process is DNA methylation (DNAm), whereby a methyl group is added to a specific part of DNA, where a cytosine base is next to a guanine base, a CpG site. We meta-analyzed epigenome-wide association studies (EWASs) of cord blood DNAm and early-childhood app…
Genome‐wide DNA methylation patterns associated with sleep and mental health in children
BACKGROUND: DNA methylation (DNAm) has been implicated in the biology of sleep. Yet, how DNAm patterns across the genome relate to different sleep outcomes, and whether these associations overlap with mental health is currently unknown. Here, we investigated associations of DNAm with sleep and mental health in a pediatric population. METHODS: This cross-sectional study included 465 10-year-old children (51.3% female) from the Generation R Study. …
No prominent works on this page.
Genome‐wide DNA methylation patterns associated with sleep and mental health in children
BACKGROUND: DNA methylation (DNAm) has been implicated in the biology of sleep. Yet, how DNAm patterns across the genome relate to different sleep outcomes, and whether these associations overlap with mental health is currently unknown. Here, we investigated associations of DNAm with sleep and mental health in a pediatric population. METHODS: This cross-sectional study included 465 10-year-old children (51.3% female) from the Generation R Study. …
An epigenome-wide association study of child appetitive traits and DNA methylation
The etiology of childhood appetitive traits is poorly understood. Early-life epigenetic processes may be involved in the developmental programming of appetite regulation in childhood. One such process is DNA methylation (DNAm), whereby a methyl group is added to a specific part of DNA, where a cytosine base is next to a guanine base, a CpG site. We meta-analyzed epigenome-wide association studies (EWASs) of cord blood DNAm and early-childhood app…
DNA methylation at birth and lateral ventricular volume in childhood
BACKGROUND: Lateral ventricular volume (LVV) enlargement has been repeatedly linked to schizophrenia; yet, what biological factors shape LVV during early development remain unclear. DNA methylation (DNAm), an essential process for neurodevelopment that is altered in schizophrenia, is a key molecular system of interest. METHODS: In this study, we conducted the first epigenome-wide association study of neonatal DNAm in cord blood with LVV in childh…
Type of information source and healthcare avoidance
Social media use was associated with higher odds of healthcare avoidance as compared to not using social media, whereas use of traditional media was related to lower avoidance. We found suggestive evidence for a role of anxiety symptoms in these associations, which should be validated by future studies. These findings emphasise the importance of disseminating accessible, objective information across a variety of media platforms, where needed tail…
Longitudinal co‐development of mental and cardio‐metabolic health from childhood to young adulthood
BACKGROUND: Depressive symptoms and cardio-metabolic risk factors often co-occur. However, our understanding of the potential mechanisms and temporal dynamics underlying their co-development remains elusive. METHODS: This population-based cohort study examined bidirectional longitudinal associations between depressive symptoms and cardio-metabolic risk factors from age 10 to 25 years, using prospective data from the ALSPAC Study. Participants wit…
Childhood internalising symptoms at ages 3 and 6
BACKGROUND: Pre- and postpartum environments and genetic effects influence childhood internalising problems, which increase depression risk. DNA methylation (DNAm) may capture some of these effects. We therefore investigated associations between child blood DNAm and internalising problems. METHODS: We meta-analysed probe and region-level epigenome-wide association studies using data from 3 European birth cohorts (ALSPAC, MoBa, Generation R; analy…
DNA methylation (4 works) · dNaM (4 works) · Epigenetics and DNA Methylation (4 works) · Biology (3 works) · Epigenetics (3 works) · Gene (3 works) · Genetics (3 works) · Mental health (3 works) · Psychology (3 works) · Cord blood (2 works)