Lynne Wagenknecht
Biographic Data
| ID | 5481064 |
|---|---|
| NAME | Lynne Wagenknecht |
| GIVEN NAMES | Lynne |
| FAMILY NAME | Wagenknecht |
| SIGNATURE | WAGENKNECHT L |
| AFFILIATIONS | Wake Forest University |
| ORCID | 0000-0002-9980-0889 |
| VERIFIED | Yes |
| TOTAL WORKS | 11 |
| TOTAL CITATIONS | 102 |
| AUTHOR COUNT | 11 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1990 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 5 |
The Academic Learning Health System
The learning health system (LHS) has emerged over the past 15 years as a concept for improving health care delivery. Core aspects of the LHS concept include: promoting improved patient care through organizational learning, innovation, and continuous quality improvement; identifying, critically assessing, and translating knowledge and evidence into improved practices; building new knowledge and evidence around how to improve health care and health…
Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey
Geographic differences in cardiovascular disease (CVD) mortality among African Americans (AAs) are well-established, but not well-characterized. Using the Minnesota Heart Survey (MHS) and Atherosclerosis Risk in Communities (ARIC) Study, we aimed to assess whether CVD risk factors drive geographic disparities in CVD mortality among AAs. ARIC risk factors were measured between1987-1989 from a population-based sample of AAs, aged 45 to 64 years, li…
Genetic Predictors of Depressive Symptoms in the Look Ahead Trial
OBJECTIVES: Numerous studies have found elevated depressive symptoms among individuals with Type 2 diabetes, yet the mechanisms remain unclear. We examined whether genetic loci previously associated with depressive symptoms predict depressive symptoms among overweight/obese individuals with Type 2 diabetes or change in depressive symptoms during behavioral weight loss. METHODS: The Illumina CARe iSelect (IBC) chip and Cardiometabochip were charac…
Egg consumption and insulin metabolism in the Insulin Resistance Atherosclerosis Study (Iras)
Objective To examine the association between egg consumption and measures of insulin sensitivity (S I ), acute insulin response (AIR) and metabolic clearance rate of insulin (MCRI). Design Cross-sectional analysis. Settings Egg consumption, categorized as I , AIR and MCRI were determined from frequently sampled intravenous glucose tolerance tests. Subjects Non-diabetic participants ( n 949) in the Insulin Resistance Atherosclerosis Study (IRAS). …
Misclassification rates for current smokers misclassified as nonsmokers
OBJECTIVES: This paper provides misclassification rates for current cigarette smokers who report themselves as nonsmokers. Such rates are important in determining smoker misclassification bias in the estimation of relative risks in passive smoking studies. METHODS: True smoking status, either occasional or regular, was determined for individual current smokers in 3 existing studies of nonsmokers by inspecting the cotinine levels of body fluids. T…
Differences in weight gain in relation to race, gender, age and education in young adults
These data indicate that young adults are at high risk of weight gain, and that weight gain was greatest among African Americans and among less educated participants. These high-risk groups can be identified and targeted for primary prevention of adult obesity in addition to population wide efforts that will be required to counteract the secular trend of increased obesity observed in US adults
Race and education in relation to stopping smoking in the US
Correlates of obesity in young black and white women
OBJECTIVES. Although differences in obesity between Blacks and Whites are well documented in adult women, less information is available on potential correlates of these differences, especially in young adults. METHODS. The association between behavioral and demographic factors and body size was assessed in 2801 Black and White women aged 18 to 30 years. RESULTS. Black women had significantly higher age-adjusted mean body mass index and subscapula…
Misclassification of smoking status in the Cardia study
BACKGROUND. Although widely used in epidemiological studies, self-report has been shown to underestimate the prevalence of cigarette smoking in some populations. METHODS. In the CARDIA study, self-report of cigarette smoking was validated against a biochemical marker of nicotine uptake, serum cotinine. RESULTS. The prevalence of smoking was slightly lower when defined by self-report (30.9%) than when defined by cotinine levels equal to or greater…
Wagenknecht and Colleagues Respond
Wagenknecht and Colleagues Respond Lynne E. Wagenknecht, Nancy J. Haley, and David R. Jacobs, Jr W J McCarthy, N H Caskey, and M E JarvikCopyRight https://doi.org/10.2105/AJPH.82.8.1173 Published Online: October 07, 2011
Racial differences in serum cotinine levels among smokers in the Coronary Artery Risk Development in (Young) Adults study
Cotinine was measured in the serum of nearly all 5,115 18-30 year old, Black and White, men and women participating in the Coronary Artery Risk Development in (Young) Adults Study, 30 percent of whom reported current cigarette smoking. Ninety-five percent of the reported smokers had serum cotinine levels indicative of smoking (greater than 13 ng/ml). The median cotinine level was higher in Black than White smokers (221 ng/ml versus 170 ng/ml; 95 …
Misclassification of smoking status in the Cardia study
BACKGROUND. Although widely used in epidemiological studies, self-report has been shown to underestimate the prevalence of cigarette smoking in some populations. METHODS. In the CARDIA study, self-report of cigarette smoking was validated against a biochemical marker of nicotine uptake, serum cotinine. RESULTS. The prevalence of smoking was slightly lower when defined by self-report (30.9%) than when defined by cotinine levels equal to or greater…
Correlates of obesity in young black and white women
OBJECTIVES. Although differences in obesity between Blacks and Whites are well documented in adult women, less information is available on potential correlates of these differences, especially in young adults. METHODS. The association between behavioral and demographic factors and body size was assessed in 2801 Black and White women aged 18 to 30 years. RESULTS. Black women had significantly higher age-adjusted mean body mass index and subscapula…
Differences in weight gain in relation to race, gender, age and education in young adults
These data indicate that young adults are at high risk of weight gain, and that weight gain was greatest among African Americans and among less educated participants. These high-risk groups can be identified and targeted for primary prevention of adult obesity in addition to population wide efforts that will be required to counteract the secular trend of increased obesity observed in US adults
Racial differences in serum cotinine levels among smokers in the Coronary Artery Risk Development in (Young) Adults study
Cotinine was measured in the serum of nearly all 5,115 18-30 year old, Black and White, men and women participating in the Coronary Artery Risk Development in (Young) Adults Study, 30 percent of whom reported current cigarette smoking. Ninety-five percent of the reported smokers had serum cotinine levels indicative of smoking (greater than 13 ng/ml). The median cotinine level was higher in Black than White smokers (221 ng/ml versus 170 ng/ml; 95 …
Misclassification rates for current smokers misclassified as nonsmokers
OBJECTIVES: This paper provides misclassification rates for current cigarette smokers who report themselves as nonsmokers. Such rates are important in determining smoker misclassification bias in the estimation of relative risks in passive smoking studies. METHODS: True smoking status, either occasional or regular, was determined for individual current smokers in 3 existing studies of nonsmokers by inspecting the cotinine levels of body fluids. T…
Wagenknecht and Colleagues Respond
Wagenknecht and Colleagues Respond Lynne E. Wagenknecht, Nancy J. Haley, and David R. Jacobs, Jr W J McCarthy, N H Caskey, and M E JarvikCopyRight https://doi.org/10.2105/AJPH.82.8.1173 Published Online: October 07, 2011
Racial differences in serum cotinine levels among smokers in the Coronary Artery Risk Development in (Young) Adults study
Cotinine was measured in the serum of nearly all 5,115 18-30 year old, Black and White, men and women participating in the Coronary Artery Risk Development in (Young) Adults Study, 30 percent of whom reported current cigarette smoking. Ninety-five percent of the reported smokers had serum cotinine levels indicative of smoking (greater than 13 ng/ml). The median cotinine level was higher in Black than White smokers (221 ng/ml versus 170 ng/ml; 95 …
Correlates of obesity in young black and white women
OBJECTIVES. Although differences in obesity between Blacks and Whites are well documented in adult women, less information is available on potential correlates of these differences, especially in young adults. METHODS. The association between behavioral and demographic factors and body size was assessed in 2801 Black and White women aged 18 to 30 years. RESULTS. Black women had significantly higher age-adjusted mean body mass index and subscapula…
Misclassification of smoking status in the Cardia study
BACKGROUND. Although widely used in epidemiological studies, self-report has been shown to underestimate the prevalence of cigarette smoking in some populations. METHODS. In the CARDIA study, self-report of cigarette smoking was validated against a biochemical marker of nicotine uptake, serum cotinine. RESULTS. The prevalence of smoking was slightly lower when defined by self-report (30.9%) than when defined by cotinine levels equal to or greater…
Wagenknecht and Colleagues Respond
Wagenknecht and Colleagues Respond Lynne E. Wagenknecht, Nancy J. Haley, and David R. Jacobs, Jr W J McCarthy, N H Caskey, and M E JarvikCopyRight https://doi.org/10.2105/AJPH.82.8.1173 Published Online: October 07, 2011
Race and education in relation to stopping smoking in the US
Differences in weight gain in relation to race, gender, age and education in young adults
These data indicate that young adults are at high risk of weight gain, and that weight gain was greatest among African Americans and among less educated participants. These high-risk groups can be identified and targeted for primary prevention of adult obesity in addition to population wide efforts that will be required to counteract the secular trend of increased obesity observed in US adults
Misclassification rates for current smokers misclassified as nonsmokers
OBJECTIVES: This paper provides misclassification rates for current cigarette smokers who report themselves as nonsmokers. Such rates are important in determining smoker misclassification bias in the estimation of relative risks in passive smoking studies. METHODS: True smoking status, either occasional or regular, was determined for individual current smokers in 3 existing studies of nonsmokers by inspecting the cotinine levels of body fluids. T…
Egg consumption and insulin metabolism in the Insulin Resistance Atherosclerosis Study (Iras)
Objective To examine the association between egg consumption and measures of insulin sensitivity (S I ), acute insulin response (AIR) and metabolic clearance rate of insulin (MCRI). Design Cross-sectional analysis. Settings Egg consumption, categorized as I , AIR and MCRI were determined from frequently sampled intravenous glucose tolerance tests. Subjects Non-diabetic participants ( n 949) in the Insulin Resistance Atherosclerosis Study (IRAS). …
Genetic Predictors of Depressive Symptoms in the Look Ahead Trial
OBJECTIVES: Numerous studies have found elevated depressive symptoms among individuals with Type 2 diabetes, yet the mechanisms remain unclear. We examined whether genetic loci previously associated with depressive symptoms predict depressive symptoms among overweight/obese individuals with Type 2 diabetes or change in depressive symptoms during behavioral weight loss. METHODS: The Illumina CARe iSelect (IBC) chip and Cardiometabochip were charac…
Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey
Geographic differences in cardiovascular disease (CVD) mortality among African Americans (AAs) are well-established, but not well-characterized. Using the Minnesota Heart Survey (MHS) and Atherosclerosis Risk in Communities (ARIC) Study, we aimed to assess whether CVD risk factors drive geographic disparities in CVD mortality among AAs. ARIC risk factors were measured between1987-1989 from a population-based sample of AAs, aged 45 to 64 years, li…
The Academic Learning Health System
The learning health system (LHS) has emerged over the past 15 years as a concept for improving health care delivery. Core aspects of the LHS concept include: promoting improved patient care through organizational learning, innovation, and continuous quality improvement; identifying, critically assessing, and translating knowledge and evidence into improved practices; building new knowledge and evidence around how to improve health care and health…
Medicine (11 works) · Demography (7 works) · Internal Medicine (7 works) · Gerontology (5 works) · Endocrinology (4 works) · Internal Medicine (4 works) · Obesity, Physical Activity, Diet (4 works) · Smoking Behavior and Cessation (4 works) · Cotinine (3 works) · Demography (3 works)