Savino Sciascia
Biographic Data
| ID | 5506144 |
|---|---|
| NAME | Savino Sciascia |
| GIVEN NAMES | Savino |
| FAMILY NAME | Sciascia |
| SIGNATURE | SCIASCIA S |
| AFFILIATIONS | University of Turin |
| ORCID | 0000-0003-1266-9441 |
| VERIFIED | Yes |
| TOTAL WORKS | 9 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 9 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2020 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Syndemic interactions in northwest Italy
BACKGROUND: Type 2 diabetes (T2DM) and depression often co-occur, generating substantial health burdens. Social determinants may shape vulnerability to both conditions. Using a syndemic framework, this study examines the clustering of T2DM, depression, education, and place of birth in a large cohort in Piedmont, Italy. METHODS: We analysed 861,300 males and 917,545 females aged 45-75 years from the Piedmont Longitudinal Study. T2DM and depression…
A global survey about undiagnosed rare diseases
Background: Undiagnosed rare diseases (URDs) are a complex and multifaceted challenge, especially in low-and medium-income countries. They affect individuals with unique clinical features and lack a clear diagnostic label. Although the Undiagnosed Diseases Network International (UDNI) definition of URDs is not universally accepted, it is widely recognized. Methods: We surveyed UDNI members and participants from other countries to explore the chal…
Clarifying healthy aging
The findings highlight substantial conceptual variability in how HA is defined and measured in RCTs. This diversity reflects the multidimensional and context-dependent nature of HA but poses challenges for synthesis and comparison across studies. A shared framework for defining HA in interventional research is needed to support evidence-based aging policies. By mapping the range of operational definitions used in RCTs, this review provides a foun…
Syndemic approach to chronic kidney disease, cardiovascular disease and educational level
INTRODUCTION: Chronic kidney disease (CKD) and end-stage renal disease (ESRD) represent significant public health challenges, linked to an elevated risk of cardiovascular disease (CVD) and influenced by socioeconomic disparities. This longitudinal study investigates the interplay between socioeconomic position (SEP), measured as educational level, CKD/ESRD and CVD using the syndemic framework. METHODS: We used data from the Piedmont Longitudinal …
Undiagnosed diseases
Introduction: Rare diseases (RD) are a health priority worldwide, overall affecting hundreds of millions of people globally. Early and accurate diagnosis is essential to support clinical care but remains challenging in many countries, especially the low- and medium-income ones. Hence, undiagnosed RD (URD) account for a significant portion of the overall RD burden. Methods: In October 2020, the Developing Nations Working Group of the Undiagnosed D…
Unmet needs in countries participating in the undiagnosed diseases network international
Background Patients, families, the healthcare system, and society as a whole are all significantly impacted by rare diseases (RDs). According to various classifications, there are currently up to 9,000 different rare diseases that have been recognized, and new diseases are discovered every month. Although very few people are affected by each uncommon disease individually, millions of people are thought to be impacted globally when all these condi…
Tailoring Tofacitinib Oral Therapy in Rheumatoid Arthritis
To support the management of rheumatoid arthritis (RA) patients treated with tofacitinib, we designed the TuTOR (tailoring tofacitinib oral therapy in rheumatoid arthritis) mobile app. The impact of the app on medical adherence was evaluated using a crossover design alternating a paper-diary and the TuTOR App. Twenty patients with RA (mean age at inclusion, 59 ± 13 years) were included in the study. A statistically significant decrease in DAS28 w…
Air Pollution from Global Health to Individual Risk Factor—Is It Time for Enviropathies in Everyday Clinical Practice
While the link between cardiovascular and respiratory conditions and air pollution is well-known, recent studies provided a growing body of evidence that polluted air, particularly air with high levels of particulate matter with a diameter smaller than 2.5 micrometers (PM 2.5), can have a range of negative impacts on health, both in terms of mortality and morbidity. It is time to emphasize the role of environmental factors as contributory factors…
Tailoring Tofacitinib Oral Therapy in Rheumatoid Arthritis
A mobile App for medication adherence might increase objectively and subjectively measured adherence
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Tailoring Tofacitinib Oral Therapy in Rheumatoid Arthritis
A mobile App for medication adherence might increase objectively and subjectively measured adherence
Tailoring Tofacitinib Oral Therapy in Rheumatoid Arthritis
To support the management of rheumatoid arthritis (RA) patients treated with tofacitinib, we designed the TuTOR (tailoring tofacitinib oral therapy in rheumatoid arthritis) mobile app. The impact of the app on medical adherence was evaluated using a crossover design alternating a paper-diary and the TuTOR App. Twenty patients with RA (mean age at inclusion, 59 ± 13 years) were included in the study. A statistically significant decrease in DAS28 w…
Air Pollution from Global Health to Individual Risk Factor—Is It Time for Enviropathies in Everyday Clinical Practice
While the link between cardiovascular and respiratory conditions and air pollution is well-known, recent studies provided a growing body of evidence that polluted air, particularly air with high levels of particulate matter with a diameter smaller than 2.5 micrometers (PM 2.5), can have a range of negative impacts on health, both in terms of mortality and morbidity. It is time to emphasize the role of environmental factors as contributory factors…
Undiagnosed diseases
Introduction: Rare diseases (RD) are a health priority worldwide, overall affecting hundreds of millions of people globally. Early and accurate diagnosis is essential to support clinical care but remains challenging in many countries, especially the low- and medium-income ones. Hence, undiagnosed RD (URD) account for a significant portion of the overall RD burden. Methods: In October 2020, the Developing Nations Working Group of the Undiagnosed D…
Unmet needs in countries participating in the undiagnosed diseases network international
Background Patients, families, the healthcare system, and society as a whole are all significantly impacted by rare diseases (RDs). According to various classifications, there are currently up to 9,000 different rare diseases that have been recognized, and new diseases are discovered every month. Although very few people are affected by each uncommon disease individually, millions of people are thought to be impacted globally when all these condi…
A global survey about undiagnosed rare diseases
Background: Undiagnosed rare diseases (URDs) are a complex and multifaceted challenge, especially in low-and medium-income countries. They affect individuals with unique clinical features and lack a clear diagnostic label. Although the Undiagnosed Diseases Network International (UDNI) definition of URDs is not universally accepted, it is widely recognized. Methods: We surveyed UDNI members and participants from other countries to explore the chal…
Clarifying healthy aging
The findings highlight substantial conceptual variability in how HA is defined and measured in RCTs. This diversity reflects the multidimensional and context-dependent nature of HA but poses challenges for synthesis and comparison across studies. A shared framework for defining HA in interventional research is needed to support evidence-based aging policies. By mapping the range of operational definitions used in RCTs, this review provides a foun…
Syndemic approach to chronic kidney disease, cardiovascular disease and educational level
INTRODUCTION: Chronic kidney disease (CKD) and end-stage renal disease (ESRD) represent significant public health challenges, linked to an elevated risk of cardiovascular disease (CVD) and influenced by socioeconomic disparities. This longitudinal study investigates the interplay between socioeconomic position (SEP), measured as educational level, CKD/ESRD and CVD using the syndemic framework. METHODS: We used data from the Piedmont Longitudinal …
Syndemic interactions in northwest Italy
BACKGROUND: Type 2 diabetes (T2DM) and depression often co-occur, generating substantial health burdens. Social determinants may shape vulnerability to both conditions. Using a syndemic framework, this study examines the clustering of T2DM, depression, education, and place of birth in a large cohort in Piedmont, Italy. METHODS: We analysed 861,300 males and 917,545 females aged 45-75 years from the Piedmont Longitudinal Study. T2DM and depression…
Medicine (7 works) · Environmental health (3 works) · Genomics and Rare Diseases (3 works) · Population (3 works) · Public health (3 works) · Autoimmune and Inflammatory Disorders Research (2 works) · Chronic Lymphocytic Leukemia Research (2 works) · Computer Science (2 works) · Developing country (2 works) · Economic growth (2 works)