Kathleen W Wyrwich
Biographic Data
| ID | 5544715 |
|---|---|
| NAME | Kathleen W Wyrwich |
| GIVEN NAMES | Kathleen W |
| FAMILY NAME | Wyrwich |
| SIGNATURE | WYRWICH K W |
| AFFILIATIONS | Saint Louis University |
| ORCID | 0000-0002-8851-350X |
| VERIFIED | Yes |
| TOTAL WORKS | 25 |
| TOTAL CITATIONS | 16 |
| WORKS AS AUTHOR | 25 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1999 |
| LATEST PUBLICATION YEAR | 2022 |
| H-INDEX | 2 |
Using qualitative methods to establish the clinically meaningful threshold for treatment success in alopecia areata
This qualitative investigation of expert clinicians-then-patients with AA confirmed that achieving an amount of 80% or more scalp hair (SALT score ≤ 20) was an appropriate individual treatment success threshold indicating clinically meaningful improvement for patients with ≥ 50% scalp hair loss. A qualitative investigation of a quantifiable treatment success threshold is possible through a well-designed interview process with expert clinicians an…
The challenges inherent with anchor-based approaches to the interpretation of important change in clinical outcome assessments
Isoqol recommends minimum standards for patient-reported outcome measures used in patient-centered outcomes and comparative effectiveness research
Is Rasch model analysis applicable in small sample size pilot studies for assessing item characteristics? An example using PROMIS pain behavior item bank data
The Fatigue Associated with Depression Questionnaire (FAsD)
The FAsD was responsive to change, and the responder definition may be used when interpreting treatment-related change. Results add to previous findings suggesting the FAsD is a useful measure of fatigue among patients with depression
Validation of Poms questionnaire in postmenopausal women
Understanding the relationships between health outcomes in generalized anxiety disorder clinical trials
Validation of the AQLQ12+ among adolescents and adults with persistent asthma
Validation of the Pagi-SYM and Pagi-QOL among healing and maintenance of erosive esophagitis clinical trial participants
Reliability and validity of the SF-12v2 in the medical expenditure panel survey
Psychometric validation of two patient-reported outcome measures to assess symptom severity and changes in symptoms in hereditary angioedema
Validity of patient-reported health-related quality of life global ratings of change using structural equation modeling
The mathematical relationship among different forms of responsiveness coefficients
A comparison of traditional and Rasch cut points for assessing clinically important change in health-related quality of life among patients with asthma
Understanding global transition assessments
Assessing Quality of Life in Clinical Trials
Estimating clinically significant differences in quality of life outcomes
Test-Retest Reliability of the Mirowsky-Ross 2 × 2 Index of the Sense of Control
This study investigated the short-term stability of the 1991 Mirowsky-Ross 2 x 2 Index of the Sense of Control. From an ongoing longitudinal study, 304 subjects were randomly selected for test-retest interviews occurring 1 to 4 days after their regularly scheduled first follow-up interview. Test-retest reliability was assessed at the item level using percent agreement and weighted kappa. At the scale score level, reliability was assessed with the…
Personal Stress, Mental Health, and Sense of Control Among Older Adults
Older adults more closely resembling those who died during 9-11 and those with greater levels of religiosity were most likely to have their sense of control affected by this catastrophic event
Age, Aging, and the Sense of Control Among Older Adults
Longitudinal studies with repeated assessments over prolonged observation periods are now needed to elucidate age-related trajectories in the sense of control
Is It Simple or Simplistic
Norman, Geoffrey R. PhD; Sloan, Jeff A. PhD; Wyrwich, Kathleen W. PhD Author Information
Interpretation of Changes in Health-related Quality of Life
BACKGROUND: A number of studies have computed the minimally important difference (MID) for health-related quality of life instruments. OBJECTIVE: To determine whether there is consistency in the magnitude of MID estimates from different instruments. METHODS: We conducted a systematic review of the literature to identify studies that computed an MID and contained sufficient information to compute an effect size (ES). Thirty-eight studies fulfilled…
Methods to Explain the Clinical Significance of Health Status Measures
Using the standard error of measurement to identify important changes on the Asthma Quality of Life Questionnaire
Linking Clinical Relevance and Statistical significance in Evaluating Intra-Individual Changes in Health-Related Quality of Life
OBJECTIVE: To compare the standard error of measurement (SEM) with established standards for clinically relevant intra-individual change in an evaluation of health-related quality of life. DESIGN: Secondary analysis of data from a randomized controlled trial. SUBJECTS: Six hundred and five outpatients with a history of cardiac problems attending the general medicine clinics of a major academic medical center. MEASURES: Baseline and follow-up inte…
Age, Aging, and the Sense of Control Among Older Adults
Longitudinal studies with repeated assessments over prolonged observation periods are now needed to elucidate age-related trajectories in the sense of control
Personal Stress, Mental Health, and Sense of Control Among Older Adults
Older adults more closely resembling those who died during 9-11 and those with greater levels of religiosity were most likely to have their sense of control affected by this catastrophic event
Linking Clinical Relevance and Statistical significance in Evaluating Intra-Individual Changes in Health-Related Quality of Life
OBJECTIVE: To compare the standard error of measurement (SEM) with established standards for clinically relevant intra-individual change in an evaluation of health-related quality of life. DESIGN: Secondary analysis of data from a randomized controlled trial. SUBJECTS: Six hundred and five outpatients with a history of cardiac problems attending the general medicine clinics of a major academic medical center. MEASURES: Baseline and follow-up inte…
Methods to Explain the Clinical Significance of Health Status Measures
Using the standard error of measurement to identify important changes on the Asthma Quality of Life Questionnaire
Personal Stress, Mental Health, and Sense of Control Among Older Adults
Older adults more closely resembling those who died during 9-11 and those with greater levels of religiosity were most likely to have their sense of control affected by this catastrophic event
Age, Aging, and the Sense of Control Among Older Adults
Longitudinal studies with repeated assessments over prolonged observation periods are now needed to elucidate age-related trajectories in the sense of control
Is It Simple or Simplistic
Norman, Geoffrey R. PhD; Sloan, Jeff A. PhD; Wyrwich, Kathleen W. PhD Author Information
Interpretation of Changes in Health-related Quality of Life
BACKGROUND: A number of studies have computed the minimally important difference (MID) for health-related quality of life instruments. OBJECTIVE: To determine whether there is consistency in the magnitude of MID estimates from different instruments. METHODS: We conducted a systematic review of the literature to identify studies that computed an MID and contained sufficient information to compute an effect size (ES). Thirty-eight studies fulfilled…
Test-Retest Reliability of the Mirowsky-Ross 2 × 2 Index of the Sense of Control
This study investigated the short-term stability of the 1991 Mirowsky-Ross 2 x 2 Index of the Sense of Control. From an ongoing longitudinal study, 304 subjects were randomly selected for test-retest interviews occurring 1 to 4 days after their regularly scheduled first follow-up interview. Test-retest reliability was assessed at the item level using percent agreement and weighted kappa. At the scale score level, reliability was assessed with the…
Estimating clinically significant differences in quality of life outcomes
A comparison of traditional and Rasch cut points for assessing clinically important change in health-related quality of life among patients with asthma
Understanding global transition assessments
Assessing Quality of Life in Clinical Trials
Validity of patient-reported health-related quality of life global ratings of change using structural equation modeling
The mathematical relationship among different forms of responsiveness coefficients
Reliability and validity of the SF-12v2 in the medical expenditure panel survey
Psychometric validation of two patient-reported outcome measures to assess symptom severity and changes in symptoms in hereditary angioedema
Understanding the relationships between health outcomes in generalized anxiety disorder clinical trials
Validation of the AQLQ12+ among adolescents and adults with persistent asthma
Validation of the Pagi-SYM and Pagi-QOL among healing and maintenance of erosive esophagitis clinical trial participants
Validation of Poms questionnaire in postmenopausal women
The Fatigue Associated with Depression Questionnaire (FAsD)
The FAsD was responsive to change, and the responder definition may be used when interpreting treatment-related change. Results add to previous findings suggesting the FAsD is a useful measure of fatigue among patients with depression
Isoqol recommends minimum standards for patient-reported outcome measures used in patient-centered outcomes and comparative effectiveness research
Is Rasch model analysis applicable in small sample size pilot studies for assessing item characteristics? An example using PROMIS pain behavior item bank data
Using qualitative methods to establish the clinically meaningful threshold for treatment success in alopecia areata
This qualitative investigation of expert clinicians-then-patients with AA confirmed that achieving an amount of 80% or more scalp hair (SALT score ≤ 20) was an appropriate individual treatment success threshold indicating clinically meaningful improvement for patients with ≥ 50% scalp hair loss. A qualitative investigation of a quantifiable treatment success threshold is possible through a well-designed interview process with expert clinicians an…
The challenges inherent with anchor-based approaches to the interpretation of important change in clinical outcome assessments
Medicine (19 works) · Psychology (15 works) · Quality of life (healthcare (11 works) · Statistics (11 works) · Internal Medicine (10 works) · Mathematics (10 works) · Public health (10 works) · Quality of Life Research (10 works) · Health Systems, Economic Evaluations, Quality of Life (9 works) · Clinical Psychology (8 works)