Peter G SMITH
Biographic Data
| ID | 5620994 |
|---|---|
| NAME | Peter G SMITH |
| GIVEN NAMES | Peter G |
| FAMILY NAME | SMITH |
| SIGNATURE | SMITH P G |
| AFFILIATIONS | London School of Hygiene & Tropical Medicine |
| ORCID | 0000-0003-0080-7560 |
| VERIFIED | Yes |
| TOTAL WORKS | 23 |
| TOTAL CITATIONS | 21 |
| AUTHOR COUNT | 23 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1973 |
| LATEST PUBLICATION YEAR | 2021 |
| H-INDEX | 3 |
Novel vaccine safety issues and areas that would benefit from further research
Vaccine licensure requires a very high safety standard and vaccines routinely used are very safe. Vaccine safety monitoring prelicensure and postlicensure enables continual assessment to ensure the benefits outweigh the risks and, when safety problems arise, they are quickly identified, characterised and further problems prevented when possible. We review five vaccine safety case studies: (1) dengue vaccine and enhanced dengue disease, (2) pandem…
Visiting Palaeolithic Art – Explorations and Archaeological Implications in Cueva De Las Monedas, Spain
Numerical chronology is one of the main sources of information by which one may contextualize prehistoric human activity more precisely. It is able to discriminate between different times of visits to caves and determine the period with which each form of evidence should be associated and the relationships between them. The application of conventional 14C and 14C‐AMS has dated visits to the Palaeolithic cave art site of Las Monedas during histori…
Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa
Conducting intervention studies in Africa, where medicines supply for chronic conditions is inequitable and patchy, raises major ethical issues. \n \nHere we discuss what should the ethical approach be for a research programme in terms of provision of a steady and sustainable supply of medicines for patients with diabetes and hypertension
Antiparasitic compounds from Cornus florida L. with activities against Plasmodium falciparum and Leishmania tarentolae
OP39 Protection by BCG Against Tuberculosis: Systematic Review and Meta-Regression Analysis
Setting Reasons for variation in BCG protection against tuberculosis are not well understood. We therefore estimated the protection provided by BCG vaccination against tuberculosis and examined reasons for variation in different settings. Methods We systematically searched English and non-English articles in 10 databases from inception to May 2009 as well as sources such as Google Scholar and trial registers to October 2009. Search terms included…
In vitro interactions of Aspilia africana (Pers.) C.D. Adams, a traditional antimalarial medicinal plant, with artemisinin against Plasmodium falciparum
The in vitro and in vivo antimalarial activity of Cardiospermum halicacabum L. and Momordica foetida Schumch. Et Thonn
Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens
Validation of the diagnosis of autism in general practitioner records
This study provides evidence that the positive predictive value of a diagnosis of autism recorded in the GPRD is high
Socioeconomic determinants of schistosomiasis in an urban area in the Northeast of Brazil
Control measures that may have a long-term effect, such as improvements in the water supply and sanitation, should be strongly encouraged. The theoretical reduction that we found in the probability of being infected if water supply and sanitation were improved highlights the importance of these measures. Implementing them would have a more permanent effect on the control of schistosomiasis and would also result in other benefits to the population
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: Design and methodology
Electronic health databases offer tremendous opportunities for evaluating the adverse effects of vaccines. However there is much scope for bias and confounding. The rigorous validation of all diagnoses and the collection of additional information by parental questionnaire in this study are essential to minimise the possibility of misleading results
Social environment, behavior, and schistosomiasis in an urban population in the Northeast of Brazil
The objective of our study was to gain greater insight into the pattern of water contact in relation to schistosomiasis among residents of São Lourenço da Mata, a town in Pernambuco, a state in the Northeast of Brazil. We had two primary objectives: 1) to identify water contact activities that were more likely to produce infection and 2) to examine the socioeconomic factors behind water contact activities. Using a sample of persons 10-25 years ol…
Child morbidity and mortality following vitamin A supplementation in Ghana: Time since dosing, number of doses, and time of year
OBJECTIVES: The impact of large-dose vitamin A supplementation given at intervals of 4 months on child mortality and morbidity was examined according to the time interval since dosing, number of doses received previously, and time of year. METHODS: Two double-blind, randomized, placebo-controlled trials of large doses of vitamin A administered at intervals of 4 months were conducted in adjacent populations in northern Ghana. RESULTS: While vitami…
BCG vaccination in the first year of life protects children of Indian subcontinent ethnic origin against tuberculosis in England
STUDY OBJECTIVE--The aim was to assess the protection conferred by BCG given during the first year of life against tuberculosis among children of Asian ethnic origin born in England. DESIGN--This was a matched case-control study. SETTING--Cases were selected from notifications of tuberculosis and controls were selected from child health or school health records in 14 English health districts. PARTICIPANTS--111 cases of childhood tuberculosis with…
Evidence for Protection by Breast-Feeding Against Infant Deaths From Infectious Diseases in Brazil
Social and Environmental Influences on Child Mortality in Brazil: Logistic Regression Analysis of Data from Census Files
Census data were used to investigate the influences of socioeconomic and environmental variables on child mortality rates in southern Brazil. By multivariate logistic regression analysis the effects of correlated factors were distinguished, after adjustment for maternal age and parity. Low family income and, to a lesser degree, low employment status of the head of the family were associated with high child mortality levels. Place of residence, ed…
Social and Environmental Influences on Child Mortality in Brazil: Logistic Regression Analysis of Data from Census Files
Census data were used to investigate the influences of socioeconomic and environmental variables on child mortality rates in southern Brazil. By multivariate logistic regression analysis the effects of correlated factors were distinguished after adjustment for maternal age and parity. Low family income and to a lesser degree low employment status of the head of the family were associated with high child mortality levels. Place of residence educat…
A case-control study of the aetiology of cryptorchidism
A study of cryptorchidism was undertaken based on patients identified through the Oxford Record Linkage Study. The cumulative lifetime incidence of archidopexy among males in the study area was estimated to be 3.38%; 88% of orchidopexies were performed on males aged 5 years and over and 32% on those aged 10 and over. In a case-control study with 146 cases ascertained at orchidopexy and 146 matched controls there was a substantially increased risk…
Statistical analysis of individually matched case-control studies in epidemiology: Factor under study a discrete variable taking multiple values
It is now well established in case-control studies with individual matching that the statistical analysis must take the fact of individual matching into account. The problems of so doing have been thoroughly dealt with for the situation of the factor of interest being a two-level factor (all-or-none response) and with one or more matched controls per patient. These results are extended in this paper to the situation where the factor can assume mu…
Person-to-person transmission of hodgkin's disease
A note on a 'close pairs' test for space clustering
Cancer in the United States
Is Hodgkin's disease contagious
Child morbidity and mortality following vitamin A supplementation in Ghana: Time since dosing, number of doses, and time of year
OBJECTIVES: The impact of large-dose vitamin A supplementation given at intervals of 4 months on child mortality and morbidity was examined according to the time interval since dosing, number of doses received previously, and time of year. METHODS: Two double-blind, randomized, placebo-controlled trials of large doses of vitamin A administered at intervals of 4 months were conducted in adjacent populations in northern Ghana. RESULTS: While vitami…
Visiting Palaeolithic Art – Explorations and Archaeological Implications in Cueva De Las Monedas, Spain
Numerical chronology is one of the main sources of information by which one may contextualize prehistoric human activity more precisely. It is able to discriminate between different times of visits to caves and determine the period with which each form of evidence should be associated and the relationships between them. The application of conventional 14C and 14C‐AMS has dated visits to the Palaeolithic cave art site of Las Monedas during histori…
A case-control study of the aetiology of cryptorchidism
A study of cryptorchidism was undertaken based on patients identified through the Oxford Record Linkage Study. The cumulative lifetime incidence of archidopexy among males in the study area was estimated to be 3.38%; 88% of orchidopexies were performed on males aged 5 years and over and 32% on those aged 10 and over. In a case-control study with 146 cases ascertained at orchidopexy and 146 matched controls there was a substantially increased risk…
Is Hodgkin's disease contagious
Person-to-person transmission of hodgkin's disease
A note on a 'close pairs' test for space clustering
Cancer in the United States
Statistical analysis of individually matched case-control studies in epidemiology: Factor under study a discrete variable taking multiple values
It is now well established in case-control studies with individual matching that the statistical analysis must take the fact of individual matching into account. The problems of so doing have been thoroughly dealt with for the situation of the factor of interest being a two-level factor (all-or-none response) and with one or more matched controls per patient. These results are extended in this paper to the situation where the factor can assume mu…
A case-control study of the aetiology of cryptorchidism
A study of cryptorchidism was undertaken based on patients identified through the Oxford Record Linkage Study. The cumulative lifetime incidence of archidopexy among males in the study area was estimated to be 3.38%; 88% of orchidopexies were performed on males aged 5 years and over and 32% on those aged 10 and over. In a case-control study with 146 cases ascertained at orchidopexy and 146 matched controls there was a substantially increased risk…
Social and Environmental Influences on Child Mortality in Brazil: Logistic Regression Analysis of Data from Census Files
Census data were used to investigate the influences of socioeconomic and environmental variables on child mortality rates in southern Brazil. By multivariate logistic regression analysis the effects of correlated factors were distinguished, after adjustment for maternal age and parity. Low family income and, to a lesser degree, low employment status of the head of the family were associated with high child mortality levels. Place of residence, ed…
Social and Environmental Influences on Child Mortality in Brazil: Logistic Regression Analysis of Data from Census Files
Census data were used to investigate the influences of socioeconomic and environmental variables on child mortality rates in southern Brazil. By multivariate logistic regression analysis the effects of correlated factors were distinguished after adjustment for maternal age and parity. Low family income and to a lesser degree low employment status of the head of the family were associated with high child mortality levels. Place of residence educat…
Evidence for Protection by Breast-Feeding Against Infant Deaths From Infectious Diseases in Brazil
BCG vaccination in the first year of life protects children of Indian subcontinent ethnic origin against tuberculosis in England
STUDY OBJECTIVE--The aim was to assess the protection conferred by BCG given during the first year of life against tuberculosis among children of Asian ethnic origin born in England. DESIGN--This was a matched case-control study. SETTING--Cases were selected from notifications of tuberculosis and controls were selected from child health or school health records in 14 English health districts. PARTICIPANTS--111 cases of childhood tuberculosis with…
Child morbidity and mortality following vitamin A supplementation in Ghana: Time since dosing, number of doses, and time of year
OBJECTIVES: The impact of large-dose vitamin A supplementation given at intervals of 4 months on child mortality and morbidity was examined according to the time interval since dosing, number of doses received previously, and time of year. METHODS: Two double-blind, randomized, placebo-controlled trials of large doses of vitamin A administered at intervals of 4 months were conducted in adjacent populations in northern Ghana. RESULTS: While vitami…
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: Design and methodology
Electronic health databases offer tremendous opportunities for evaluating the adverse effects of vaccines. However there is much scope for bias and confounding. The rigorous validation of all diagnoses and the collection of additional information by parental questionnaire in this study are essential to minimise the possibility of misleading results
Social environment, behavior, and schistosomiasis in an urban population in the Northeast of Brazil
The objective of our study was to gain greater insight into the pattern of water contact in relation to schistosomiasis among residents of São Lourenço da Mata, a town in Pernambuco, a state in the Northeast of Brazil. We had two primary objectives: 1) to identify water contact activities that were more likely to produce infection and 2) to examine the socioeconomic factors behind water contact activities. Using a sample of persons 10-25 years ol…
Socioeconomic determinants of schistosomiasis in an urban area in the Northeast of Brazil
Control measures that may have a long-term effect, such as improvements in the water supply and sanitation, should be strongly encouraged. The theoretical reduction that we found in the probability of being infected if water supply and sanitation were improved highlights the importance of these measures. Implementing them would have a more permanent effect on the control of schistosomiasis and would also result in other benefits to the population
Validation of the diagnosis of autism in general practitioner records
This study provides evidence that the positive predictive value of a diagnosis of autism recorded in the GPRD is high
In vitro interactions of Aspilia africana (Pers.) C.D. Adams, a traditional antimalarial medicinal plant, with artemisinin against Plasmodium falciparum
The in vitro and in vivo antimalarial activity of Cardiospermum halicacabum L. and Momordica foetida Schumch. Et Thonn
Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens
Antiparasitic compounds from Cornus florida L. with activities against Plasmodium falciparum and Leishmania tarentolae
OP39 Protection by BCG Against Tuberculosis: Systematic Review and Meta-Regression Analysis
Setting Reasons for variation in BCG protection against tuberculosis are not well understood. We therefore estimated the protection provided by BCG vaccination against tuberculosis and examined reasons for variation in different settings. Methods We systematically searched English and non-English articles in 10 databases from inception to May 2009 as well as sources such as Google Scholar and trial registers to October 2009. Search terms included…
Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa
Conducting intervention studies in Africa, where medicines supply for chronic conditions is inequitable and patchy, raises major ethical issues. \n \nHere we discuss what should the ethical approach be for a research programme in terms of provision of a steady and sustainable supply of medicines for patients with diabetes and hypertension
Novel vaccine safety issues and areas that would benefit from further research
Vaccine licensure requires a very high safety standard and vaccines routinely used are very safe. Vaccine safety monitoring prelicensure and postlicensure enables continual assessment to ensure the benefits outweigh the risks and, when safety problems arise, they are quickly identified, characterised and further problems prevented when possible. We review five vaccine safety case studies: (1) dengue vaccine and enhanced dengue disease, (2) pandem…
Visiting Palaeolithic Art – Explorations and Archaeological Implications in Cueva De Las Monedas, Spain
Numerical chronology is one of the main sources of information by which one may contextualize prehistoric human activity more precisely. It is able to discriminate between different times of visits to caves and determine the period with which each form of evidence should be associated and the relationships between them. The application of conventional 14C and 14C‐AMS has dated visits to the Palaeolithic cave art site of Las Monedas during histori…
Medicine (21 works) · Environmental health (9 works) · Immunology (7 works) · Population (7 works) · Geography (6 works) · Pathology (6 works) · Biology (5 works) · Child Nutrition and Water Access (5 works) · Pediatrics (5 works) · Demography (4 works)