Marco Cascella
Biographic Data
| ID | 5658298 |
|---|---|
| NAME | Marco Cascella |
| GIVEN NAMES | Marco |
| FAMILY NAME | Cascella |
| SIGNATURE | CASCELLA M |
| AFFILIATIONS | Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" |
| ORCID | 0000-0002-5236-3132 |
| VERIFIED | Yes |
| TOTAL WORKS | 11 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 11 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2016 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
The medial prefrontal cortex as an integrative hub in chronic pain: Network mechanisms and the enabling role of artificial intelligence
Chronic pain is recognized as a disorder of distributed brain networks rather than the consequence of persistent nociceptive input. Among these networks, the medial prefrontal cortex (mPFC) is a key integrative hub linking sensory processing with affective, cognitive, and stress-related dimensions of pain. Evidence from neuroimaging, neurochemical, and longitudinal studies indicates that mPFC dysfunction contributes to impaired top-down modulatio…
Advantages of Remimazolam in Pediatric Anesthesia: A Narrative Review
Remimazolam is an ultra-short-acting benzodiazepine developed according to the "soft drug" concept and characterized by rapid onset, predictable offset, organ-independent metabolism, and the availability of a specific antagonist. Due to these pharmacological features, this drug represents a particularly attractive option for pediatric anesthesia and sedation, a field in which traditional agents are often limited by hemodynamic instability, prolon…
Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia
The search for an ideal anesthetic has always been a major goal in anesthesiology. In recent years, the introduction of ciprofol has marked a major breakthrough in the pharmacological field, following the introduction of dexmedetomidine. Ciprofol has similar characteristics to propofol but with greater hemodynamic stability. Furthermore, it overcomes one of the most common discomforts associated with propofol: pain at the injection site. These ch…
Evaluating the Feasibility of ChatGPT in Healthcare: An Analysis of Multiple Clinical and Research Scenarios
This paper aims to highlight the potential applications and limits of a large language model (LLM) in healthcare. ChatGPT is a recently developed LLM that was trained on a massive dataset of text for dialogue with users. Although AI-based language models like ChatGPT have demonstrated impressive capabilities, it is uncertain how well they will perform in real-world scenarios, particularly in fields such as medicine where high-level and complex th…
Proscription lists and predatory publishers: Pointing to careful certifications
Wireless Peripheral Nerve Stimulation for The Upper Limb: A Case Report
Peripheral neuro-stimulation (PNS) has been proved to be effective for the treatment of neuropathic pain as well as other painful conditions. We discuss two approaches to PNS placement in the upper extremity. The first case describes a neuropathic syndrome after the traumatic amputation of the distal phalanx of the fifth digit secondary to a work accident with lack of responsiveness to a triple conservative therapy. An upper arm region approach f…
Neurostimulation for Chronic Low Back Pain during Pregnancy: Implications for Child and Mother Safety
Pain therapy for low back pain in pregnancy is a very topical issue. In fact, it is necessary to balance the patient's needs to control pain with the need to manage a pregnancy without negative effects on the fetus. We report a case of a 37-year-old woman with low back pain treated with neurostimulation before pregnancy. She described severe chronic low back pain unresponsive to pharmacologic treatments. We first implanted a subcutaneous stimulat…
Incidence of Acute and Chronic Post-Thoracotomy Pain in Pediatric Patients
We studied acute and chronic pain in pediatric patients who underwent thoracotomy for benign disease with a follow-up of at least three months. A telephone interview investigated about the presence of pain and the analgesic therapy in progress. The results were compared with the anesthetic technique, postoperative pain and the adequacy of pain therapy, both during the first week after surgery and at the time of interview. Fifty-six families conse…
A Delphi Consensus Approach for the Management of Chronic Pain during and after the Covid-19 Era
Due to a lack of published evidence on the topic, a modified Delphi approach was used to develop recommendations useful for chronic pain management during and after the COVID-19 pandemic. Focusing on the available literature and personal clinical expertise, an Italian board of nine professionals from different disciplines identified four main topics: prevention of chronic pain, treatment of chronic pain, consequences of inadequate treatment, and …
The Illness and Death of Enrico Caruso (1873–1921): A Medical Chorus Out of Tune
Taphophobia and ‘life preserving coffins’ in the nineteenth century
In 1891 the Italian psychiatrist Enrico Morselli (1852-1929) described taphophobia, defining it as an extreme condition of claustrophobia due to the fear of being buried alive. This rare psychopathological phenomenon reflects an ancient fear, and its origin is not known. Taphophobia is closely linked to the problem of apparent death and premature burial. In the nineteenth century, scientists and authors paid particular attention to the issue of a…
No prominent works on this page.
The Illness and Death of Enrico Caruso (1873–1921): A Medical Chorus Out of Tune
Taphophobia and ‘life preserving coffins’ in the nineteenth century
In 1891 the Italian psychiatrist Enrico Morselli (1852-1929) described taphophobia, defining it as an extreme condition of claustrophobia due to the fear of being buried alive. This rare psychopathological phenomenon reflects an ancient fear, and its origin is not known. Taphophobia is closely linked to the problem of apparent death and premature burial. In the nineteenth century, scientists and authors paid particular attention to the issue of a…
Incidence of Acute and Chronic Post-Thoracotomy Pain in Pediatric Patients
We studied acute and chronic pain in pediatric patients who underwent thoracotomy for benign disease with a follow-up of at least three months. A telephone interview investigated about the presence of pain and the analgesic therapy in progress. The results were compared with the anesthetic technique, postoperative pain and the adequacy of pain therapy, both during the first week after surgery and at the time of interview. Fifty-six families conse…
A Delphi Consensus Approach for the Management of Chronic Pain during and after the Covid-19 Era
Due to a lack of published evidence on the topic, a modified Delphi approach was used to develop recommendations useful for chronic pain management during and after the COVID-19 pandemic. Focusing on the available literature and personal clinical expertise, an Italian board of nine professionals from different disciplines identified four main topics: prevention of chronic pain, treatment of chronic pain, consequences of inadequate treatment, and …
Neurostimulation for Chronic Low Back Pain during Pregnancy: Implications for Child and Mother Safety
Pain therapy for low back pain in pregnancy is a very topical issue. In fact, it is necessary to balance the patient's needs to control pain with the need to manage a pregnancy without negative effects on the fetus. We report a case of a 37-year-old woman with low back pain treated with neurostimulation before pregnancy. She described severe chronic low back pain unresponsive to pharmacologic treatments. We first implanted a subcutaneous stimulat…
Evaluating the Feasibility of ChatGPT in Healthcare: An Analysis of Multiple Clinical and Research Scenarios
This paper aims to highlight the potential applications and limits of a large language model (LLM) in healthcare. ChatGPT is a recently developed LLM that was trained on a massive dataset of text for dialogue with users. Although AI-based language models like ChatGPT have demonstrated impressive capabilities, it is uncertain how well they will perform in real-world scenarios, particularly in fields such as medicine where high-level and complex th…
Proscription lists and predatory publishers: Pointing to careful certifications
Wireless Peripheral Nerve Stimulation for The Upper Limb: A Case Report
Peripheral neuro-stimulation (PNS) has been proved to be effective for the treatment of neuropathic pain as well as other painful conditions. We discuss two approaches to PNS placement in the upper extremity. The first case describes a neuropathic syndrome after the traumatic amputation of the distal phalanx of the fifth digit secondary to a work accident with lack of responsiveness to a triple conservative therapy. An upper arm region approach f…
The medial prefrontal cortex as an integrative hub in chronic pain: Network mechanisms and the enabling role of artificial intelligence
Chronic pain is recognized as a disorder of distributed brain networks rather than the consequence of persistent nociceptive input. Among these networks, the medial prefrontal cortex (mPFC) is a key integrative hub linking sensory processing with affective, cognitive, and stress-related dimensions of pain. Evidence from neuroimaging, neurochemical, and longitudinal studies indicates that mPFC dysfunction contributes to impaired top-down modulatio…
Advantages of Remimazolam in Pediatric Anesthesia: A Narrative Review
Remimazolam is an ultra-short-acting benzodiazepine developed according to the "soft drug" concept and characterized by rapid onset, predictable offset, organ-independent metabolism, and the availability of a specific antagonist. Due to these pharmacological features, this drug represents a particularly attractive option for pediatric anesthesia and sedation, a field in which traditional agents are often limited by hemodynamic instability, prolon…
Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia
The search for an ideal anesthetic has always been a major goal in anesthesiology. In recent years, the introduction of ciprofol has marked a major breakthrough in the pharmacological field, following the introduction of dexmedetomidine. Ciprofol has similar characteristics to propofol but with greater hemodynamic stability. Furthermore, it overcomes one of the most common discomforts associated with propofol: pain at the injection site. These ch…
Medicine (4 works) · Chronic pain (3 works) · Physical therapy (3 works) · Political science (3 works) · Anesthesia (2 works) · Anesthesia and Neurotoxicity Research (2 works) · Anesthesia and Pain Management (2 works) · Anesthesia and Sedative Agents (2 works) · Anesthetic (2 works) · Computer Science (2 works)