Achilles Katamba
Datos Biográficos
| ID | 5822742 |
|---|---|
| NOMBRE | Achilles Katamba |
| NOMBRES | Achilles |
| APELLIDO | Katamba |
| FIRMA | KATAMBA A |
| AFILIACIONES | Makerere University |
| ORCID | 0000-0002-2347-4183 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 23 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 23 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2014 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Resources to implement general population mobile chest x-ray screening for tuberculosis in Uganda
Mobile chest X-ray (CXR) screening interventions are recommended for tuberculosis (TB) screening in high-burden settings, but implementation costs are variable and underreported. Using time-driven activity-based costing, we evaluated the costs of implementing general-population mobile CXR screening in peri-urban Uganda. We conducted a micro-costing analysis of mobile CXR screening using data from an ongoing randomized crossover trial. We adopted …
Barriers and facilitators to viral load suppression among adolescents and young people living with HIV receiving intensive adherence counselling in east central Uganda
Suboptimal viral load (VL) suppression among adolescents and young people living with HIV (AYPLHIV) remains a major challenge to HIV control in Uganda. Although Intensive Adherence Counselling (IAC) is implemented as a structured intervention for individuals with unsuppressed viral loads, suppression rates among AYPLHIV remain low. Evidence on the contextual factors shaping VL suppression after IAC remains limited. This study explored barriers an…
Association of Human Cytomegalovirus exposure with tuberculosis disease in South African adults with presumptive tuberculosis
Recent studies suggested that human cytomegalovirus (HCMV) exposure may increase tuberculosis (TB) disease risk. We assessed the association between active HCMV infection and recent HCMV exposure with tuberculosis (TB) disease among TB-presumptive South African adults. This was a cross-sectional case-control study that utilized stored plasma and serum samples collected from adults (≥18 years) with presumptive TB self-presenting to primary care cl…
Tuberculosis laboratory capacity building in the WHO African Region
Tuberculosis remains a leading infectious disease killer in the World Health Organization African Region, with 2.5 million cases and 404,000 deaths in 2023, including 112,000 people with HIV. There is slow progress with only 42% of the 75% targeted reduction in death by 2025. Out of 60,266 estimated multidrug-resistant TB cases in 2023, only 22,515 were notified. Laboratory diagnostic services in the African region still need urgent attention. By…
Identifying mechanisms by which social determinants of health impact TB diagnostic evaluation uptake in Uganda
Biomedical interventions alone are unlikely to address the spectrum of SDoH-related barriers to equitable completion of TB diagnostic evaluation. Linking barriers to a behavior change model such as COM-B may help guide the design and evaluation of appropriate people-centered strategies that integrate social and economic supports with clinical and public health programs or services
Evaluating the implementation of weekly rifapentine-isoniazid (3HP) for tuberculosis prevention among people living with HIV in Uganda
Three months of isoniazid-rifapentine (3HP) is being scaled up for tuberculosis (TB) preventive treatment (TPT) among people living with HIV (PLHIV) in high-burden settings. More evidence is needed to identify factors influencing successful 3HP delivery. We conducted a qualitative assessment of 3HP delivery nested within the 3HP Options Trial, which compared three optimized strategies for delivering 3HP: facilitated directly observed therapy (DOT…
Feasibility of a social protection linkage program for individuals at-risk for tuberculosis in Uganda
Social protection interventions have the potential to accelerate progress towards global tuberculosis (TB) targets. We piloted a screening and linkage program at four community health centers (HC) to enroll adults seeking TB diagnostic evaluation services into existing government-supported social protection programs in Uganda. From May-December 2021, health center staff were asked to screen adults being evaluated for TB for eligibility for govern…
Uptake of community antiretroviral group delivery models for persons living with HIV in Arua district, Uganda
Community antiretroviral groups (CAGs) is one of the innovative and efficient differentiated service delivery models (DSDM) for reaching persons needing human immunodeficiency virus (HIV) treatment in the community. Since DSDM adoption in Uganda, evidence suggests better care outcomes for patients in DSDM compared to counterparts in routine health facility care. However, uptake of CAG models for eligible community groups of persons living with HI…
A user-centred implementation strategy for tuberculosis contact investigation in Uganda
The trial was registered(ClinicalTrials.gov Identifier NCT05640648) on 16 November 2022, after the trial launch on 7 March 2022
Theory-Informed Design of a Tailored Strategy for Implementing Household TB Contact Investigation in Uganda
Since 2012, the World Health Organization has recommended household contact investigation as an evidence-based intervention to find and treat individuals with active tuberculosis (TB), the most common infectious cause of death worldwide after COVID-19. Unfortunately, uptake of this recommendation has been suboptimal in low- and middle-income countries, where the majority of affected individuals reside, and little is known about how to effectively…
Cost-effectiveness analysis of human-centred design for global health interventions
INTRODUCTION: Human-centred design (HCD) is a problem-solving approach that is increasingly used to develop new global health interventions. However, there is often a large initial cost associated with HCD, and global health decision-makers would benefit from an improved understanding of the cost-effectiveness of HCD, particularly the trade-offs between the up-front costs of design and the long-term costs of delivering health interventions. METHO…
Is aggregated surveillance data a reliable method for constructing tuberculosis care cascades? A secondary data analysis from Uganda
To accelerate tuberculosis (TB) control and elimination, reliable data is needed to improve the quality of TB care. We assessed agreement between a surveillance dataset routinely collected for Uganda’s national TB program and a high-fidelity dataset collected from the same source documents for a research study from 32 health facilities in 2017 and 2019 for six measurements: 1) Smear-positive and 2) GeneXpert-positive diagnoses, 3) bacteriological…
Perceptions, preferences, and experiences of tuberculosis education and counselling among patients and providers in Kampala, Uganda
Tuberculosis (TB) education seeks to increase patient knowledge about TB, while TB counselling seeks to offer tailored advice and support for medication adherence. While universally recommended, little is known about how to provide effective, efficient, patient-centred TB education and counselling (TEC) in low-income, high HIV-TB burden settings. We sought to characterise stakeholder perceptions of TEC in a public, primary care facility in Kampal…
Cango Lyec (Healing the Elephant)
Cango Lyec participants displayed lower than previously reported yet significant levels of probable PTSD and depression. Based on findings from this study, providing trauma-informed care, ensuring food and housing security, eliminating gender-based violence, and reintegrating former abductees remain important tasks to facilitate post-conflict rehabilitation in Northern Uganda
Implementation, interrupted
Many implementation efforts experience interruptions, especially in settings with developing health systems. Approaches for evaluating interruptions are needed to inform re-implementation strategies. We sought to devise an approach for evaluating interruptions by exploring the sustainability of a programme that implemented diabetes mellitus (DM) screening within tuberculosis clinics in Uganda in 2017. In 2019, we conducted nine interviews with cl…
Households experiencing catastrophic costs due to tuberculosis in Uganda
Despite free health care in public health facilities, over half of Ugandan TB affected households experience catastrophic costs. Roll out of social protection interventions like TB assistance programs, insurance schemes, and enforcement of legislation related to social protection through multi-sectoral action plans with central NTP involvement would palliate these costs
Experiences and intentions of Ugandan household tuberculosis contacts receiving test results via text message
Household contacts experienced relief when they received results. However, they were less confident about results delivered via SMS than results delivered by LHWs. Delivery of results by SMS should complement continued interaction with LHWs, not replace them
Patient and health system factors associated with pretreatment loss to follow up among patients diagnosed with tuberculosis using Xpert® MTB/RIF testing in Uganda
In public health facilities in Uganda, we found a high rate of pretreatment loss to follow up especially among TBHIV co-infected patients diagnosed at high volume health facilities. Interventions to improve the efficiency of Xpert® MTB/RIF testing, including monitoring of the TB care cascade should be developed and implemented
Beyond solidarity and mutual aid
Drawing from ethnographic data collected between 2012 and 2014 and January and June 2018 in Luwero district, Uganda, this article questions the romanticised depiction of burial groups as a means of enhancing social support, a sense of solidarity and mutual aid. We found that the felt sense of identity and belonging for members is not shared across community members, and that solidary relations between members and non-group members in the communit…
Sex-related alcohol expectancies and high-risk sexual behaviour among drinking adults in Kampala, Uganda
Alcohol consumption, a risk factor for HIV transmission in sub-Saharan Africa, is considered high in Uganda. A cross sectional study was conducted to determine whether sex-related expectations about the effects of alcohol explain the association between alcohol use and risky sexual behaviours in a population-based sample of adults in Kampala. Associations between alcohol use (current and higher risk drinking) and high-risk sexual behaviours (mult…
The State of Ambient Air Quality in Two Ugandan Cities
Air pollution is one of the leading global public health risks but its magnitude in many developing countries' cities is not known. We aimed to measure the concentration of particulate matter with aerodynamic diameter <2.5 μm (PM2.5), nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O3) pollutants in two Ugandan cities (Kampala and Jinja). PM2.5, O3, temperature and humidity were measured with real-time monitors, while NO2 and SO2 were me…
Determinants of hypertension in a young adult Ugandan population in epidemiological transition—the Mepi-CVD survey
There is a high prevalence of high blood pressure in this young periurban population of Uganda with sub-optimal diagnosis and control. There is previously undocumented high rate of treatment, a unique finding that may be exploited to drive efforts to control hypertension. Specific programs for early diagnosis and treatment of hypertension among the young should be developed to improve control of hypertension. The relationship between HIV infectio…
Perceptions of quality of life among Ugandan patients living with HIV
Individuals living with HIV receiving treatment or in care experienced an improved quality of life in this setting, although the situation for many remains precarious
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Perceptions of quality of life among Ugandan patients living with HIV
Individuals living with HIV receiving treatment or in care experienced an improved quality of life in this setting, although the situation for many remains precarious
Sex-related alcohol expectancies and high-risk sexual behaviour among drinking adults in Kampala, Uganda
Alcohol consumption, a risk factor for HIV transmission in sub-Saharan Africa, is considered high in Uganda. A cross sectional study was conducted to determine whether sex-related expectations about the effects of alcohol explain the association between alcohol use and risky sexual behaviours in a population-based sample of adults in Kampala. Associations between alcohol use (current and higher risk drinking) and high-risk sexual behaviours (mult…
The State of Ambient Air Quality in Two Ugandan Cities
Air pollution is one of the leading global public health risks but its magnitude in many developing countries' cities is not known. We aimed to measure the concentration of particulate matter with aerodynamic diameter <2.5 μm (PM2.5), nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O3) pollutants in two Ugandan cities (Kampala and Jinja). PM2.5, O3, temperature and humidity were measured with real-time monitors, while NO2 and SO2 were me…
Determinants of hypertension in a young adult Ugandan population in epidemiological transition—the Mepi-CVD survey
There is a high prevalence of high blood pressure in this young periurban population of Uganda with sub-optimal diagnosis and control. There is previously undocumented high rate of treatment, a unique finding that may be exploited to drive efforts to control hypertension. Specific programs for early diagnosis and treatment of hypertension among the young should be developed to improve control of hypertension. The relationship between HIV infectio…
Households experiencing catastrophic costs due to tuberculosis in Uganda
Despite free health care in public health facilities, over half of Ugandan TB affected households experience catastrophic costs. Roll out of social protection interventions like TB assistance programs, insurance schemes, and enforcement of legislation related to social protection through multi-sectoral action plans with central NTP involvement would palliate these costs
Experiences and intentions of Ugandan household tuberculosis contacts receiving test results via text message
Household contacts experienced relief when they received results. However, they were less confident about results delivered via SMS than results delivered by LHWs. Delivery of results by SMS should complement continued interaction with LHWs, not replace them
Patient and health system factors associated with pretreatment loss to follow up among patients diagnosed with tuberculosis using Xpert® MTB/RIF testing in Uganda
In public health facilities in Uganda, we found a high rate of pretreatment loss to follow up especially among TBHIV co-infected patients diagnosed at high volume health facilities. Interventions to improve the efficiency of Xpert® MTB/RIF testing, including monitoring of the TB care cascade should be developed and implemented
Beyond solidarity and mutual aid
Drawing from ethnographic data collected between 2012 and 2014 and January and June 2018 in Luwero district, Uganda, this article questions the romanticised depiction of burial groups as a means of enhancing social support, a sense of solidarity and mutual aid. We found that the felt sense of identity and belonging for members is not shared across community members, and that solidary relations between members and non-group members in the communit…
Implementation, interrupted
Many implementation efforts experience interruptions, especially in settings with developing health systems. Approaches for evaluating interruptions are needed to inform re-implementation strategies. We sought to devise an approach for evaluating interruptions by exploring the sustainability of a programme that implemented diabetes mellitus (DM) screening within tuberculosis clinics in Uganda in 2017. In 2019, we conducted nine interviews with cl…
Theory-Informed Design of a Tailored Strategy for Implementing Household TB Contact Investigation in Uganda
Since 2012, the World Health Organization has recommended household contact investigation as an evidence-based intervention to find and treat individuals with active tuberculosis (TB), the most common infectious cause of death worldwide after COVID-19. Unfortunately, uptake of this recommendation has been suboptimal in low- and middle-income countries, where the majority of affected individuals reside, and little is known about how to effectively…
Cost-effectiveness analysis of human-centred design for global health interventions
INTRODUCTION: Human-centred design (HCD) is a problem-solving approach that is increasingly used to develop new global health interventions. However, there is often a large initial cost associated with HCD, and global health decision-makers would benefit from an improved understanding of the cost-effectiveness of HCD, particularly the trade-offs between the up-front costs of design and the long-term costs of delivering health interventions. METHO…
Is aggregated surveillance data a reliable method for constructing tuberculosis care cascades? A secondary data analysis from Uganda
To accelerate tuberculosis (TB) control and elimination, reliable data is needed to improve the quality of TB care. We assessed agreement between a surveillance dataset routinely collected for Uganda’s national TB program and a high-fidelity dataset collected from the same source documents for a research study from 32 health facilities in 2017 and 2019 for six measurements: 1) Smear-positive and 2) GeneXpert-positive diagnoses, 3) bacteriological…
Perceptions, preferences, and experiences of tuberculosis education and counselling among patients and providers in Kampala, Uganda
Tuberculosis (TB) education seeks to increase patient knowledge about TB, while TB counselling seeks to offer tailored advice and support for medication adherence. While universally recommended, little is known about how to provide effective, efficient, patient-centred TB education and counselling (TEC) in low-income, high HIV-TB burden settings. We sought to characterise stakeholder perceptions of TEC in a public, primary care facility in Kampal…
Cango Lyec (Healing the Elephant)
Cango Lyec participants displayed lower than previously reported yet significant levels of probable PTSD and depression. Based on findings from this study, providing trauma-informed care, ensuring food and housing security, eliminating gender-based violence, and reintegrating former abductees remain important tasks to facilitate post-conflict rehabilitation in Northern Uganda
Feasibility of a social protection linkage program for individuals at-risk for tuberculosis in Uganda
Social protection interventions have the potential to accelerate progress towards global tuberculosis (TB) targets. We piloted a screening and linkage program at four community health centers (HC) to enroll adults seeking TB diagnostic evaluation services into existing government-supported social protection programs in Uganda. From May-December 2021, health center staff were asked to screen adults being evaluated for TB for eligibility for govern…
Uptake of community antiretroviral group delivery models for persons living with HIV in Arua district, Uganda
Community antiretroviral groups (CAGs) is one of the innovative and efficient differentiated service delivery models (DSDM) for reaching persons needing human immunodeficiency virus (HIV) treatment in the community. Since DSDM adoption in Uganda, evidence suggests better care outcomes for patients in DSDM compared to counterparts in routine health facility care. However, uptake of CAG models for eligible community groups of persons living with HI…
A user-centred implementation strategy for tuberculosis contact investigation in Uganda
The trial was registered(ClinicalTrials.gov Identifier NCT05640648) on 16 November 2022, after the trial launch on 7 March 2022
Evaluating the implementation of weekly rifapentine-isoniazid (3HP) for tuberculosis prevention among people living with HIV in Uganda
Three months of isoniazid-rifapentine (3HP) is being scaled up for tuberculosis (TB) preventive treatment (TPT) among people living with HIV (PLHIV) in high-burden settings. More evidence is needed to identify factors influencing successful 3HP delivery. We conducted a qualitative assessment of 3HP delivery nested within the 3HP Options Trial, which compared three optimized strategies for delivering 3HP: facilitated directly observed therapy (DOT…
Tuberculosis laboratory capacity building in the WHO African Region
Tuberculosis remains a leading infectious disease killer in the World Health Organization African Region, with 2.5 million cases and 404,000 deaths in 2023, including 112,000 people with HIV. There is slow progress with only 42% of the 75% targeted reduction in death by 2025. Out of 60,266 estimated multidrug-resistant TB cases in 2023, only 22,515 were notified. Laboratory diagnostic services in the African region still need urgent attention. By…
Identifying mechanisms by which social determinants of health impact TB diagnostic evaluation uptake in Uganda
Biomedical interventions alone are unlikely to address the spectrum of SDoH-related barriers to equitable completion of TB diagnostic evaluation. Linking barriers to a behavior change model such as COM-B may help guide the design and evaluation of appropriate people-centered strategies that integrate social and economic supports with clinical and public health programs or services
Resources to implement general population mobile chest x-ray screening for tuberculosis in Uganda
Mobile chest X-ray (CXR) screening interventions are recommended for tuberculosis (TB) screening in high-burden settings, but implementation costs are variable and underreported. Using time-driven activity-based costing, we evaluated the costs of implementing general-population mobile CXR screening in peri-urban Uganda. We conducted a micro-costing analysis of mobile CXR screening using data from an ongoing randomized crossover trial. We adopted …
Barriers and facilitators to viral load suppression among adolescents and young people living with HIV receiving intensive adherence counselling in east central Uganda
Suboptimal viral load (VL) suppression among adolescents and young people living with HIV (AYPLHIV) remains a major challenge to HIV control in Uganda. Although Intensive Adherence Counselling (IAC) is implemented as a structured intervention for individuals with unsuppressed viral loads, suppression rates among AYPLHIV remain low. Evidence on the contextual factors shaping VL suppression after IAC remains limited. This study explored barriers an…
Association of Human Cytomegalovirus exposure with tuberculosis disease in South African adults with presumptive tuberculosis
Recent studies suggested that human cytomegalovirus (HCMV) exposure may increase tuberculosis (TB) disease risk. We assessed the association between active HCMV infection and recent HCMV exposure with tuberculosis (TB) disease among TB-presumptive South African adults. This was a cross-sectional case-control study that utilized stored plasma and serum samples collected from adults (≥18 years) with presumptive TB self-presenting to primary care cl…
Medicine (17 obras) · Nursing (10 obras) · Tuberculosis (10 obras) · Tuberculosis Research and Epidemiology (9 obras) · Environmental health (8 obras) · Family medicine (7 obras) · Psychological intervention (7 obras) · Public health (7 obras) · Biostatistics (6 obras) · Population (6 obras)