Carolyn Bolton‐Moore
Biographic Data
| ID | 5854272 |
|---|---|
| NAME | Carolyn Bolton‐Moore |
| GIVEN NAMES | Carolyn |
| FAMILY NAME | Bolton‐Moore |
| SIGNATURE | MOORE C B |
| AFFILIATIONS | Centre for Infectious Disease Research in Zambia |
| ORCID | 0000-0001-9103-7746 |
| VERIFIED | Yes |
| TOTAL WORKS | 16 |
| TOTAL CITATIONS | 2 |
| WORKS AS AUTHOR | 16 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1960 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Patterns of engagement in care during clients’ first 12 months after HIV treatment initiation in Zambia
BACKGROUND: The first year after HIV treatment initiation or re-initiation is the period of highest risk of a treatment interruption or disengagement, yet little is known about the timing, patterns and effects of interruptions in the early treatment period. METHODS: Using routinely collected electronic medical record data from 543 Zambian facilities from 2018 to 2023, we described patterns of engagement during the first year of HIV treatment. We …
Evaluation of the SKILLZ intervention to promote HIV testing and contraception uptake in adolescent girls in Lusaka, Zambia
Adolescent girls are at disproportionately high-risk for HIV and unintended pregnancy. Effective interventions to increase uptake of HIV testing and contraceptives are urgently needed. Our cluster-randomized controlled trial in 46 schools in Lusaka, Zambia evaluated the SKILLZ intervention: (a) 12 after-school sessions of sexuality and sexual and reproductive health (SRH) education culminating in a community “graduation” soccer event where a pop-…
Implementing Sars-CoV-2 routine surveillance in antenatal care in Zambia, 2021–2022
Incorporating SARS-CoV-2 surveillance into routine antenatal care is feasible and potentially sustainable when existing health system infrastructure, human resources, and surveillance systems are leveraged. Yet, careful planning is needed to anticipate implementation challenges and ensure high-quality data collection
A hybrid effectiveness implementation trial testing an HIV and STI prevention program for mother figures and their adolescent girls and young women delivered by peer leaders
ClinicalTrials.gov, NCT06503666, Registered on 10 July 2024
An exploration of multi-level factors affecting routine linkage to HIV care in Zambia’s Pepfar-supported treatment program in the treat all era
Multiple steps from HIV diagnosis to treatment initiation and confirmed engagement with the health system are required for people living with HIV to establish full linkage to care in the modern treat all era. We undertook a qualitative study to gain an in-depth understanding of the impeding and enabling factors at each step of this linkage pathway. In-depth interviews were conducted with fifty-eight people living with HIV recruited from ten routi…
Trends in Sars-CoV-2 seroprevalence among pregnant women attending first antenatal care visits in Zambia
SARS-CoV-2 serosurveys help estimate the extent of transmission and guide the allocation of COVID-19 vaccines. We measured SARS-CoV-2 seroprevalence among women attending ANC clinics to assess exposure trends over time in Zambia. We conducted repeated cross-sectional SARS-CoV-2 seroprevalence surveys among pregnant women aged 15–49 years attending their first ANC visits in four districts of Zambia (two urban and two rural) during September 2021-S…
Integrating isoniazid preventive therapy into the fast-track HIV treatment model in urban Zambia
Most people living with HIV (PLHIV) established on treatment in Zambia receive multi-month prescribing and dispensing (MMSD) antiretroviral therapy (ART) and are enrolled in less-intensive differentiated service delivery (DSD) models such as Fast Track (FT), where clients collect ART every 3–6 months and make clinical visits every 6 months. In 2019, Zambia introduced Isoniazid Preventive Therapy (IPT) with scheduled visits at 2 weeks and 1, 3, an…
Mitigating the effects of Covid-19 on HIV treatment and care in Lusaka, Zambia
INTRODUCTION: The Zambian Ministry of Health (MoH) issued COVID-19 mitigation guidance for HIV care immediately after the first COVID-19 case was confirmed in Zambia on 18 March 2020. The Centre for Infectious Disease Research in Zambia implemented MoH guidance by: 1) extending antiretroviral therapy (ART) refill duration to 6 multi-month dispensation (6MMD) and 2) task-shifting communication and mobilisation of those in HIV care to collect their…
Evaluation of kidney function among people living with HIV initiating antiretroviral therapy in Zambia
As the response to the HIV epidemic in sub-Saharan Africa continues to mature, a growing number of people living with HIV (PLHIV) are aging and risk for non-communicable diseases increases. Routine laboratory tests of serum creatinine have been conducted to assess HIV treatment (ART) suitability. Here we utilize those measures to assess kidney function impairment among those initiating ART. Identification of non-communicable disease (NCD) risks a…
A controlled study to assess the effects of a Fast Track (FT) service delivery model among stable HIV patients in Lusaka Zambia
Fast Track models—in which patients coming to facility to pick up medications minimize waiting times through foregoing clinical review and collecting pre-packaged medications—present a potential strategy to reduce the burden of treatment. We examine effects of a Fast Track model (FT) in a real-world clinical HIV treatment program on retention to care comparing two clinics initiating FT care to five similar (in size and health care level), standar…
HIV care experiences and health priorities during the first wave of Covid-19
Clients' HIV care and health priorities during the first wave of COVID-19 in Lusaka province were varied with a combination of positive and negative experiences that occurred especially at health system and individual levels, while at household level, the experiences were all negative. More research is needed to understand how patients practice resiliency in the widespread context of socio-economic instability. Governments and patients must work …
Growth patterns of infants with in- utero HIV and ARV exposure in Cape Town, South Africa and Lusaka, Zambia
Infant growth trajectories differed by country, highlighting the importance of studying contextual influences on outcomes of infants who were HEU
Findings from a comprehensive diarrhoea prevention and treatment programme in Lusaka, Zambia
Well-packaged diarrhoea preventive and treatment interventions delivered at the clinic and community-level could potentially reduce probability of death among children aged 1-59 months
Contraceptive use among HIV-infected women and men receiving antiretroviral therapy in Lusaka, Zambia
While FP-ART integration may be a promising strategy for increasing FP service uptake, such services must focus on assessing sexual activity and advocating for dual method use to increase effective contraceptive use and prevent unintended pregnancies
Integrating HIV treatment with primary care outpatient services
BACKGROUND: Integration of HIV treatment with other primary care services has been argued to potentially improve effectiveness, efficiency and equity. However, outside the field of reproductive health, there is limited empirical evidence regarding the scope or depth of integrated HIV programmes or their relative benefits. Moreover, the body of work describing operational models of integrated service-delivery in context remains thin. Between 2008 …
The Effect of Knowledge of Results Before and After a Response
Integrating HIV treatment with primary care outpatient services
BACKGROUND: Integration of HIV treatment with other primary care services has been argued to potentially improve effectiveness, efficiency and equity. However, outside the field of reproductive health, there is limited empirical evidence regarding the scope or depth of integrated HIV programmes or their relative benefits. Moreover, the body of work describing operational models of integrated service-delivery in context remains thin. Between 2008 …
The Effect of Knowledge of Results Before and After a Response
Integrating HIV treatment with primary care outpatient services
BACKGROUND: Integration of HIV treatment with other primary care services has been argued to potentially improve effectiveness, efficiency and equity. However, outside the field of reproductive health, there is limited empirical evidence regarding the scope or depth of integrated HIV programmes or their relative benefits. Moreover, the body of work describing operational models of integrated service-delivery in context remains thin. Between 2008 …
Findings from a comprehensive diarrhoea prevention and treatment programme in Lusaka, Zambia
Well-packaged diarrhoea preventive and treatment interventions delivered at the clinic and community-level could potentially reduce probability of death among children aged 1-59 months
Contraceptive use among HIV-infected women and men receiving antiretroviral therapy in Lusaka, Zambia
While FP-ART integration may be a promising strategy for increasing FP service uptake, such services must focus on assessing sexual activity and advocating for dual method use to increase effective contraceptive use and prevent unintended pregnancies
Mitigating the effects of Covid-19 on HIV treatment and care in Lusaka, Zambia
INTRODUCTION: The Zambian Ministry of Health (MoH) issued COVID-19 mitigation guidance for HIV care immediately after the first COVID-19 case was confirmed in Zambia on 18 March 2020. The Centre for Infectious Disease Research in Zambia implemented MoH guidance by: 1) extending antiretroviral therapy (ART) refill duration to 6 multi-month dispensation (6MMD) and 2) task-shifting communication and mobilisation of those in HIV care to collect their…
Evaluation of kidney function among people living with HIV initiating antiretroviral therapy in Zambia
As the response to the HIV epidemic in sub-Saharan Africa continues to mature, a growing number of people living with HIV (PLHIV) are aging and risk for non-communicable diseases increases. Routine laboratory tests of serum creatinine have been conducted to assess HIV treatment (ART) suitability. Here we utilize those measures to assess kidney function impairment among those initiating ART. Identification of non-communicable disease (NCD) risks a…
A controlled study to assess the effects of a Fast Track (FT) service delivery model among stable HIV patients in Lusaka Zambia
Fast Track models—in which patients coming to facility to pick up medications minimize waiting times through foregoing clinical review and collecting pre-packaged medications—present a potential strategy to reduce the burden of treatment. We examine effects of a Fast Track model (FT) in a real-world clinical HIV treatment program on retention to care comparing two clinics initiating FT care to five similar (in size and health care level), standar…
HIV care experiences and health priorities during the first wave of Covid-19
Clients' HIV care and health priorities during the first wave of COVID-19 in Lusaka province were varied with a combination of positive and negative experiences that occurred especially at health system and individual levels, while at household level, the experiences were all negative. More research is needed to understand how patients practice resiliency in the widespread context of socio-economic instability. Governments and patients must work …
Growth patterns of infants with in- utero HIV and ARV exposure in Cape Town, South Africa and Lusaka, Zambia
Infant growth trajectories differed by country, highlighting the importance of studying contextual influences on outcomes of infants who were HEU
Integrating isoniazid preventive therapy into the fast-track HIV treatment model in urban Zambia
Most people living with HIV (PLHIV) established on treatment in Zambia receive multi-month prescribing and dispensing (MMSD) antiretroviral therapy (ART) and are enrolled in less-intensive differentiated service delivery (DSD) models such as Fast Track (FT), where clients collect ART every 3–6 months and make clinical visits every 6 months. In 2019, Zambia introduced Isoniazid Preventive Therapy (IPT) with scheduled visits at 2 weeks and 1, 3, an…
An exploration of multi-level factors affecting routine linkage to HIV care in Zambia’s Pepfar-supported treatment program in the treat all era
Multiple steps from HIV diagnosis to treatment initiation and confirmed engagement with the health system are required for people living with HIV to establish full linkage to care in the modern treat all era. We undertook a qualitative study to gain an in-depth understanding of the impeding and enabling factors at each step of this linkage pathway. In-depth interviews were conducted with fifty-eight people living with HIV recruited from ten routi…
Trends in Sars-CoV-2 seroprevalence among pregnant women attending first antenatal care visits in Zambia
SARS-CoV-2 serosurveys help estimate the extent of transmission and guide the allocation of COVID-19 vaccines. We measured SARS-CoV-2 seroprevalence among women attending ANC clinics to assess exposure trends over time in Zambia. We conducted repeated cross-sectional SARS-CoV-2 seroprevalence surveys among pregnant women aged 15–49 years attending their first ANC visits in four districts of Zambia (two urban and two rural) during September 2021-S…
Patterns of engagement in care during clients’ first 12 months after HIV treatment initiation in Zambia
BACKGROUND: The first year after HIV treatment initiation or re-initiation is the period of highest risk of a treatment interruption or disengagement, yet little is known about the timing, patterns and effects of interruptions in the early treatment period. METHODS: Using routinely collected electronic medical record data from 543 Zambian facilities from 2018 to 2023, we described patterns of engagement during the first year of HIV treatment. We …
Evaluation of the SKILLZ intervention to promote HIV testing and contraception uptake in adolescent girls in Lusaka, Zambia
Adolescent girls are at disproportionately high-risk for HIV and unintended pregnancy. Effective interventions to increase uptake of HIV testing and contraceptives are urgently needed. Our cluster-randomized controlled trial in 46 schools in Lusaka, Zambia evaluated the SKILLZ intervention: (a) 12 after-school sessions of sexuality and sexual and reproductive health (SRH) education culminating in a community “graduation” soccer event where a pop-…
Implementing Sars-CoV-2 routine surveillance in antenatal care in Zambia, 2021–2022
Incorporating SARS-CoV-2 surveillance into routine antenatal care is feasible and potentially sustainable when existing health system infrastructure, human resources, and surveillance systems are leveraged. Yet, careful planning is needed to anticipate implementation challenges and ensure high-quality data collection
A hybrid effectiveness implementation trial testing an HIV and STI prevention program for mother figures and their adolescent girls and young women delivered by peer leaders
ClinicalTrials.gov, NCT06503666, Registered on 10 July 2024
Medicine (13 works) · HIV/AIDS Research and Interventions (12 works) · Family medicine (9 works) · Demography (8 works) · Environmental health (8 works) · Pediatrics (8 works) · Population (8 works) · Public health (7 works) · Internal Medicine (6 works) · Adolescent Sexual and Reproductive Health (5 works)