Paula Pacheco
Biographic Data
| ID | 6020800 |
|---|---|
| NAME | Paula Pacheco |
| GIVEN NAMES | Paula |
| FAMILY NAME | Pacheco |
| SIGNATURE | PACHECO P |
| AFFILIATIONS | Instituto Gulbenkian de Ciência |
| VERIFIED | No |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 6 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2006 |
| LATEST PUBLICATION YEAR | 2020 |
| H-INDEX | 1 |
Importance and vulnerability of the world’s water towers
Climate Change and Water Resources in Arid Mountains
Genetic signature of the São Miguel island population (Azores) assessed by 21 microsatellite loci
To study the genetic diversity of São Miguel's population we compared 21 microsatellite loci in 204 individuals from São Miguel island and 103 individuals from mainland Portugal. The results show that São Miguel and mainland Portugal populations have an average gene diversity of 0.767 and 0.765, respectively. Allele frequencies of all markers are comparable to other European populations. This observation is corroborated by the genetic relationshi…
Evaluation of linkage disequilibrium on the Xq13.3 region
The design of genetic studies of complex diseases is dependent on the extent and distribution of linkage disequilibrium (LD) across the genome in different populations. Here, we characterize the extent of LD in the Azores (Western, Central, and Eastern island groups) and mainland Portugal populations. LD was evaluated in the Xq13.3 region by genotyping eight STR markers spanning 20.9 Mb. Standardized multiallelic disequilibrium coefficient (D') a…
Azores Islands
Overall, the Azorean population can be analysed as a homogeneous genetic group, which consequently, would present, possibly, the same drug-reaction profile. In terms of genomic medicine, these results will have a significant impact on the design of future genetic and pharmacogenomic studies in the Azorean population
Assessment of Azorean ancestry by Alu insertion polymorphisms
Knowledge of population ancestry from genetic markers is essential, for example, to understand the history of human migration and to carry out admixture and association studies. Here we assess the genome ancestry of the Azorean population through analysis of six Alu polymorphic sites (TPA-25, ACE, APO, B65, PV92, and D1) in 65 Azoreans and 30 Portuguese unrelated blood donors and compare data for the Y-chromosome and mtDNA. Allele frequencies wer…
Assessment of Azorean ancestry by Alu insertion polymorphisms
Knowledge of population ancestry from genetic markers is essential, for example, to understand the history of human migration and to carry out admixture and association studies. Here we assess the genome ancestry of the Azorean population through analysis of six Alu polymorphic sites (TPA-25, ACE, APO, B65, PV92, and D1) in 65 Azoreans and 30 Portuguese unrelated blood donors and compare data for the Y-chromosome and mtDNA. Allele frequencies wer…
Genetic signature of the São Miguel island population (Azores) assessed by 21 microsatellite loci
To study the genetic diversity of São Miguel's population we compared 21 microsatellite loci in 204 individuals from São Miguel island and 103 individuals from mainland Portugal. The results show that São Miguel and mainland Portugal populations have an average gene diversity of 0.767 and 0.765, respectively. Allele frequencies of all markers are comparable to other European populations. This observation is corroborated by the genetic relationshi…
Evaluation of linkage disequilibrium on the Xq13.3 region
The design of genetic studies of complex diseases is dependent on the extent and distribution of linkage disequilibrium (LD) across the genome in different populations. Here, we characterize the extent of LD in the Azores (Western, Central, and Eastern island groups) and mainland Portugal populations. LD was evaluated in the Xq13.3 region by genotyping eight STR markers spanning 20.9 Mb. Standardized multiallelic disequilibrium coefficient (D') a…
Azores Islands
Overall, the Azorean population can be analysed as a homogeneous genetic group, which consequently, would present, possibly, the same drug-reaction profile. In terms of genomic medicine, these results will have a significant impact on the design of future genetic and pharmacogenomic studies in the Azorean population
Climate Change and Water Resources in Arid Mountains
Importance and vulnerability of the world’s water towers
Biology (4 works) · Genetics (4 works) · Demography (3 works) · Evolutionary biology (3 works) · Forensic and Genetic Research (3 works) · Gene (3 works) · Genetic diversity and population structure (3 works) · Geography (3 works) · Population (3 works) · Allele (2 works)