Kathryn Anastos
Biographic Data
| ID | 6065972 |
|---|---|
| NAME | Kathryn Anastos |
| GIVEN NAMES | Kathryn |
| FAMILY NAME | Anastos |
| SIGNATURE | ANASTOS K |
| AFFILIATIONS | Albert Einstein College of Medicine |
| ORCID | 0000-0002-0769-6405 |
| VERIFIED | Yes |
| TOTAL WORKS | 39 |
| TOTAL CITATIONS | 12 |
| WORKS AS AUTHOR | 39 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2002 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 2 |
Self-reported and Point-of-Care Biomarkers of Substance Use Measures Among Older Adults with HIV from Low- and Middle-Income Countries
Measuring alcohol and other drug (AOD) use remains challenging in HIV care in low- and middle-income countries, where self-report and point-of-care (POC) urine biomarkers capture different time windows. Among 2,059 people with HIV aged 40 years or older across eight IeDEA clinics (2020 to 2022), we examined what self-reported AOD use (AUDIT, ASSIST) and POC urine tests (uEtG for alcohol; 5-panel drug screen) each capture. Self-report identified m…
Validation of an Extended Sexual Orientation and Gender Identity Measure in a Racially and Ethnically Diverse Cohort of People Living with or at Risk for HIV Infection
Despite becoming a routine part of clinical care, collection of sexual orientation and gender identity (SOGI) is not standardized, and common measures might not reflect the full range of LGBTQ+ experiences. In this study, we tested a novel expanded SOGI measure that addresses these concerns in a racially and ethnically diverse HIV cohort study. Participants ( N = 885) were randomized to complete either a common SOGI measure with fewer SOGI choice…
Disentangling depression in women with diabetes
While preliminary, our findings suggest that associations between inflammatory biomarkers and depression may not be consistent across all depressive measures or symptom dimensions. Although larger samples with repeated measures are needed, findings from this exploratory study suggest that including inflammatory measures beyond hsCRP and IL-6, together with tools that capture distinct depressive symptom dimensions, may help to inform future precis…
Factors associated with viral load suppression in pregnant and postpartum women living with HIV in Rwanda
Introduction: Achieving and maintaining HIV viral load suppression (VLS) in pregnant and postpartum women living with HIV (WLWH) is critical for their health and to prevent mother-to-child transmission. However, data on VLS in this population are limited. This study aimed to evaluate the prevalence and factors associated with VLS among pregnant and postpartum WLWH in Rwanda within 12 months of enrolling in antenatal care. Methods: An open observa…
Mental health-related help-seeking and the role of HIV care providers
Mental health disorders are common among people with HIV (PWH), and the overwhelming majority of PWH with mental health disorders do not receive evidence-based mental health care. One promising strategy to increase access to evidence-based mental health care for PWH is to integrate mental health screening and treatment for common mental disorders and unhealthy drinking into HIV care. However, little is known about how PWH view the role of HIV car…
Gender, mental health symptoms, loss to clinic, and viral non-suppression 6 months after HIV care initiation among a cohort of people with HIV in Cameroon
Men initiating HIV care with poor mental health may be particularly vulnerable to unstable care engagement and viral non-suppression. Interventions are needed for men specifically to foster improved mental health
Attrition from Care and Barriers to PrEP Use Among Key Populations in Kinshasa, DRC
Female sex workers (FSW) and gay and other men who have sex with men (MSM) are disproportionately affected by HIV. Oral pre-exposure prophylaxis (PrEP) is increasingly available in African countries, including the Democratic Republic of Congo (DRC), but data on factors influencing PrEP use remain limited. This multiple methods study examined PrEP attrition patterns and barriers to engagement among FSW and MSM in Kinshasa, DRC, using programmatic …
Awareness and willingness to use pre-exposure prophylaxis for HIV prevention among men who have sex with men in Rwanda
Introduction: Pre-exposure Prophylaxis (PrEP) is a daily pill aimed at reducing HIV transmission risk when taken as prescribed. It's highly recommended for high-risk Men who have sex with Men (MSM). This study aimed to assess PrEP awareness and willingness to use it among Rwandan MSM, a critical aspect given PrEP's proven effectiveness. The findings are expected to inform policy decisions and further advance the implementation of PrEP strategies.…
Understanding depression and the PHQ-9 items among people living with HIV
People living with HIV (PLWH) are disproportionately affected by depression, which often remains underdiagnosed and untreated, negatively impacting quality of life and treatment outcomes. Low resource settings often lack clinical professionals to identify depression, therefore screening tools such as the PHQ-9 allow for broader depression screening. This qualitative study among PLWH in Yaoundé Cameroon aimed to a) explore local understandings of …
Intersectional HIV- and Depression-Related Stigma Among People with HIV Entering HIV Care in Cameroon
Experiences of stigma and HIV care engagement in the context of Treat All in Rwanda
Treat All policy in Rwanda has heightened the visibility of HIV at the individual and social levels, which has influenced HIV stigma, normalization, psychosocial support and care engagement in complex ways. Leveraging the individual and community support described by PLHIV to deliver evidence-based, peer or provider-delivered stigma reduction interventions may aid in attaining Treat All goals
Coping Strategies and Symptoms of Mental Health Disorders Among People with HIV Initiating HIV Care in Cameroon
Little is known about the coping strategies used among people with HIV (PWH), especially in sub-Saharan Africa, and the extent to which adaptive or maladaptive coping strategies are associated with symptoms of mental health disorders. We interviewed 426 PWH initiating HIV care in Cameroon and reported the prevalence of adaptive and maladaptive coping strategies, overall and by presence of symptoms of depression, anxiety, and PTSD. Log binominal r…
Association Between Clinical Encounter Frequency and HIV-Related Stigma Among Newly-Diagnosed People Living with HIV in Rwanda
HIV-related stigma in healthcare settings remains a key barrier to engaging people living with HIV (PLHIV) in care. This study investigated the association between clinical encounter frequency and HIV-related anticipated, enacted, and internalized stigma among newly-diagnosed PLHIV in Rwanda. From October 2020 to May 2022, we collected data from adult PLHIV on antiretroviral therapy (ART) in Kigali, Rwanda who were participating in a randomized, …
Glucocorticoid Receptor Function and Cognitive Performance in Women With HIV
OBJECTIVE: Alterations in glucocorticoid receptor (GCR) function may be a risk factor for cognitive complications among older people with human immunodeficiency virus (HIV). We evaluated whether HIV serostatus and age modify the GCR function-cognition association among women. METHODS: Eighty women with HIV ( n = 40, 50 years of age [older]) and 80 HIV-uninfected women ( n = 40 older, n = 40 younger) enrolled in the Women's Interagency HIV Study c…
Association of Social Needs With Uncontrolled Viremia in People With Hiv
Age-varying Associations of Depressive Symptoms and Heavy Episodic Drinking Throughout Adulthood Among People with HIV and Receiving care in Cameroon Within a National “treat all” Policy
Associations between population density and clinical and sociodemographic factors in women living with HIV in the Southern United States
To explore the associations of urbanicity with clinical/behavioral outcomes and sociodemographic factors among women living with HIV in the Southern United States, 523 participants of the Women's Interagency HIV Study were classified into population density quartiles. Rural-Urban Commuting Area codes revealed that 7% resided in areas where >30% commute to urban areas, 2% resided in small towns or rural areas, and 91% resided in varying densities …
Underestimation of potentially traumatic events resulting from underreporting of physical and sexual violence among people entering care for HIV in Cameroon
PTE assessment tools should assess exposure to behaviorally specific acts of violence to ensure appropriate referral to services among survivors of IPV. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
Depressive Symptoms, Gender, Disclosure, and HIV Care Stage Among People Living with HIV in Cameroon
Gender, Mental Health, and Entry Into Care with Advanced HIV Among People Living with HIV in Cameroon Under a National ‘Treat All’ Policy
Heavy episodic drinking and HIV disclosure by HIV treatment status among People with HIV in IeDEA Cameroon
The prevalence of recent HED was high among PWH in care. HED prevalence was highest among men and recent ART initiators. Longitudinal analyses should explore how HIV disclosure may support PWH in reducing or abstaining from HED through social support. Systematic HED screening and referral to care should be included in routine HIV clinical care, particularly for men, to improve engagement in the HIV care continuum in Cameroon
Lifetime Prevalence and Correlates of Female Condom Use for Anal Sex in a Geographically Diverse Sample of Men Who Have Sex with Men (MSM) in the United States
OBJECTIVES: Examine use of the female condom (FC) for anal sex among Men who have sex with men (MSM) in the United States (US). METHODS: An online survey among 3,837 MSM. RESULTS: 5.2% had used the FC for anal sex. Use was higher among those who had used the FC for vaginal sex (OR=14.39, p<0.001), those with multiple partners, (OR=2.68, p=0.004), and those who were HIV-positive (OR=2.07, p<0.001) or on PrEP (OR=2.66, p<0.001). CONCLUSIONS: FC use…
Neighborhood Poverty and Control of HIV, Hypertension, and Diabetes in the Women’s Interagency HIV Study
Repeated Measures Regression in Laboratory, Clinical and Environmental Research
When using repeated measures linear regression models to make causal inference in laboratory, clinical and environmental research, it is typically assumed that the within-subject association of differences (or changes) in predictor variable values across replicates is the same as the between-subject association of differences in those predictor variable values. However, this is often false. For example, with body weight as the predictor variable …
Prevalence, Comorbidity, and Correlates of Psychiatric and Substance Use Disorders and Associations with HIV Risk Behaviors in a Multisite Cohort of Women Living with HIV
We used the World Health Organization's Composite International Diagnostic Interview to determine the prevalence, comorbidity, and correlates of lifetime and 12-month behavioral health disorders in a multisite cohort of 1027 women living with HIV in the United States. Most (82.6%) had one or more lifetime disorders including 34.2% with mood disorders, 61.6% with anxiety disorders, and 58.3% with substance use disorders. Over half (53.9%) had at l…
Use of Highly Active Antiretroviral Therapy in a Cohort of HIV-Seropositive Women
Objectives. This study examined longitudinal trends in use of highly active antiretroviral therapy (HAART) among a cohort of HIV-positive participants in the Women's Interagency HIV Study. Methods. Beginning in 1994, 1690 HIV-positive women reported detailed information about their use of antiretroviral therapy at 6-month study visits. Multivariate logistic and Cox regression analyses were used to estimate the likelihood of antiretroviral therapy…
Association of Cigarette Smoking With HIV Prognosis Among Women in the Haart Era
Objective. We assessed the association of cigarette smoking with the effectiveness of highly active antiretroviral therapy (HAART) among low-income women. Methods. Data were analyzed from the Women’s Interagency HIV Study, a multisite longitudinal study up to 7.9 years for 924 women representing 72% of all women who initiated HAART between July 1, 1995, and September 30, 2003. Results. When Cox’s regression was used after control for age, race, h…
Use of Highly Active Antiretroviral Therapy in a Cohort of HIV-Seropositive Women
Objectives. This study examined longitudinal trends in use of highly active antiretroviral therapy (HAART) among a cohort of HIV-positive participants in the Women's Interagency HIV Study. Methods. Beginning in 1994, 1690 HIV-positive women reported detailed information about their use of antiretroviral therapy at 6-month study visits. Multivariate logistic and Cox regression analyses were used to estimate the likelihood of antiretroviral therapy…
Dissatisfaction with medical care among women with HIV
Studies have shown that women with HIV/AIDS in the USA are less likely than men to have access to appropriate health care and to utilize services, including the latest antiretroviral drug therapies. One explanation for this underutilization is patient dissatisfaction with medical care. Dissatisfaction with care has been shown to be associated not only with treatment underutilization, but also with discontinuity of care and poor clinical outcomes.…
Effects of treated and untreated depressive symptoms on highly active antiretroviral therapy use in a US multi-site cohort of HIV-positive women
This study examines the effects of treated and untreated depressive symptoms on the likelihood of utilization of highly active antiretroviral therapy (HAART) among a multi-site cohort of HIV-infected women who screened positive for probable depression. Data were collected biannually from 1996 through 2001 in a prospective cohort study. Random-effects regression analysis was used to estimate the longitudinal effects of mental health treatment on t…
Aging and HIV Infection
Association of Cigarette Smoking With HIV Prognosis Among Women in the Haart Era
Objective. We assessed the association of cigarette smoking with the effectiveness of highly active antiretroviral therapy (HAART) among low-income women. Methods. Data were analyzed from the Women’s Interagency HIV Study, a multisite longitudinal study up to 7.9 years for 924 women representing 72% of all women who initiated HAART between July 1, 1995, and September 30, 2003. Results. When Cox’s regression was used after control for age, race, h…
HIV status, trust in health care providers, and distrust in the health care system among Bronx women
Trust in health care providers and the health care system are essential. This study examined factors associated with trust in providers and distrust in the health care system among minority HIV-positive and -negative women. Interviews were conducted and laboratory tests performed with 102 women from the Women's Interagency HIV Study Bronx site. Interviews collected information about trust in providers, distrust in the system, substance use, menta…
Does Patient–Provider Racial/Ethnic Concordance Influence Ratings of Trust in People with HIV Infection
Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women
Depression is common in people with cardiovascular diseases (CVD) and those with HIV, and is a risk factor for CVD-related mortality. However, little is known about whether HIV influences the relationship between depression and cardiovascular risk. A total of 526 HIV-infected and 132 uninfected women from the Women's Interagency HIV Study were included in an analysis of women who completed twice-yearly study visits over 9.5 years. CVD risk was ca…
The impact of HIV status, HIV disease progression, and post-traumatic stress symptoms on the health-related quality of life of Rwandan women genocide survivors
Do HIV-Positive Women Receive Depression Treatment that Meets Best Practice Guidelines
Sexual Behavior and Risk Practices of HIV Positive and HIV Negative Rwandan Women
Decentralizing Maternity Services to Increase Skilled Attendance at Birth and Antenatal Care Utilization in Rural Rwanda
Prevalence, Comorbidity, and Correlates of Psychiatric and Substance Use Disorders and Associations with HIV Risk Behaviors in a Multisite Cohort of Women Living with HIV
We used the World Health Organization's Composite International Diagnostic Interview to determine the prevalence, comorbidity, and correlates of lifetime and 12-month behavioral health disorders in a multisite cohort of 1027 women living with HIV in the United States. Most (82.6%) had one or more lifetime disorders including 34.2% with mood disorders, 61.6% with anxiety disorders, and 58.3% with substance use disorders. Over half (53.9%) had at l…
Missed Opportunities for HIV Prevention
Prevalence of and Factors Associated with the Use of HIV Serosorting and Other Biomedical Prevention Strategies Among Men Who Have Sex with Men in a US Nationwide Survey
Repeated Measures Regression in Laboratory, Clinical and Environmental Research
When using repeated measures linear regression models to make causal inference in laboratory, clinical and environmental research, it is typically assumed that the within-subject association of differences (or changes) in predictor variable values across replicates is the same as the between-subject association of differences in those predictor variable values. However, this is often false. For example, with body weight as the predictor variable …
Lifetime Prevalence and Correlates of Female Condom Use for Anal Sex in a Geographically Diverse Sample of Men Who Have Sex with Men (MSM) in the United States
OBJECTIVES: Examine use of the female condom (FC) for anal sex among Men who have sex with men (MSM) in the United States (US). METHODS: An online survey among 3,837 MSM. RESULTS: 5.2% had used the FC for anal sex. Use was higher among those who had used the FC for vaginal sex (OR=14.39, p<0.001), those with multiple partners, (OR=2.68, p=0.004), and those who were HIV-positive (OR=2.07, p<0.001) or on PrEP (OR=2.66, p<0.001). CONCLUSIONS: FC use…
Neighborhood Poverty and Control of HIV, Hypertension, and Diabetes in the Women’s Interagency HIV Study
Associations between population density and clinical and sociodemographic factors in women living with HIV in the Southern United States
To explore the associations of urbanicity with clinical/behavioral outcomes and sociodemographic factors among women living with HIV in the Southern United States, 523 participants of the Women's Interagency HIV Study were classified into population density quartiles. Rural-Urban Commuting Area codes revealed that 7% resided in areas where >30% commute to urban areas, 2% resided in small towns or rural areas, and 91% resided in varying densities …
Underestimation of potentially traumatic events resulting from underreporting of physical and sexual violence among people entering care for HIV in Cameroon
PTE assessment tools should assess exposure to behaviorally specific acts of violence to ensure appropriate referral to services among survivors of IPV. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
Depressive Symptoms, Gender, Disclosure, and HIV Care Stage Among People Living with HIV in Cameroon
Gender, Mental Health, and Entry Into Care with Advanced HIV Among People Living with HIV in Cameroon Under a National ‘Treat All’ Policy
Heavy episodic drinking and HIV disclosure by HIV treatment status among People with HIV in IeDEA Cameroon
The prevalence of recent HED was high among PWH in care. HED prevalence was highest among men and recent ART initiators. Longitudinal analyses should explore how HIV disclosure may support PWH in reducing or abstaining from HED through social support. Systematic HED screening and referral to care should be included in routine HIV clinical care, particularly for men, to improve engagement in the HIV care continuum in Cameroon
Glucocorticoid Receptor Function and Cognitive Performance in Women With HIV
OBJECTIVE: Alterations in glucocorticoid receptor (GCR) function may be a risk factor for cognitive complications among older people with human immunodeficiency virus (HIV). We evaluated whether HIV serostatus and age modify the GCR function-cognition association among women. METHODS: Eighty women with HIV ( n = 40, 50 years of age [older]) and 80 HIV-uninfected women ( n = 40 older, n = 40 younger) enrolled in the Women's Interagency HIV Study c…
Association of Social Needs With Uncontrolled Viremia in People With Hiv
Medicine (34 works) · HIV/AIDS Research and Interventions (31 works) · Family medicine (20 works) · Psychiatry (19 works) · Public health (19 works) · Internal Medicine (18 works) · HIV, Drug Use, Sexual Risk (15 works) · Human immunodeficiency virus (HIV (14 works) · Demography (13 works) · Environmental health (13 works)