Justin Lessler
Biographic Data
| ID | 6067601 |
|---|---|
| NAME | Justin Lessler |
| GIVEN NAMES | Justin |
| FAMILY NAME | Lessler |
| SIGNATURE | LESSLER J |
| AFFILIATIONS | Johns Hopkins University |
| ORCID | 0000-0002-9741-8109 |
| VERIFIED | Yes |
| TOTAL WORKS | 9 |
| TOTAL CITATIONS | 2 |
| AUTHOR COUNT | 9 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2010 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Continued T12 transmission and shared antibiotic resistance during 2018–2023 Vibrio cholerae outbreaks in Cameroon
Seventh pandemic Vibrio cholerae was first identified in Cameroon in 1971, causing several sporadic disease clusters with few cases. More recent years have seen larger cholera outbreaks, but the mechanism behind these periodic outbreaks is poorly understood, and it is unclear the degree to which antibiotic resistant strains contribute to disease burden and spread. We used whole genome sequencing to characterize 13 V. cholerae isolates from the 20…
Infectious disease surveillance needs for the United States
The COVID-19 pandemic has highlighted the need to upgrade systems for infectious disease surveillance and forecasting and modeling of the spread of infection, both of which inform evidence-based public health guidance and policies. Here, we discuss requirements for an effective surveillance system to support decision making during a pandemic, drawing on the lessons of COVID-19 in the U.S., while looking to jurisdictions in the U.S. and beyond to …
HIV epidemiologic trends among occupational groups in Rakai, Uganda
Certain occupations have been associated with heightened risk of HIV acquisition and spread in sub-Saharan Africa, including female bar and restaurant work and male transportation work. However, data on changes in population prevalence of HIV infection and HIV incidence within occupations following mass scale-up of African HIV treatment and prevention programs is very limited. We evaluated prospective data collected between 1999 and 2016 from the…
Effect of non-pharmaceutical interventions in the early phase of the Covid-19 epidemic in Saudi Arabia
Non-pharmaceutical interventions have been widely employed to control the COVID-19 pandemic. Their associated effect on SARS-CoV-2 transmission have however been unequally studied across regions. Few studies have focused on the Gulf states despite their potential role for global pandemic spread, in particular in the Kingdom of Saudi Arabia through religious pilgrimages. We study the association between NPIs and SARS-CoV-2 transmission in the King…
Collaborative Hubs
The Incubation Period of Coronavirus Disease 2019 (Covid-19) From Publicly Reported Confirmed Cases
BACKGROUND: A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incubation period for clinical disease (coronavirus disease 2019 [COVID-19]), which has important implications for surveillance and control activities. OBJECTIVE: To estimate the length of the incubation period of COVID-19 a…
Epidemiology and transmission of Covid-19 in 391 cases and 1286 of their close contacts in Shenzhen, China
Impact of interventions and the incidence of ebola virus disease in Liberia—implications for future epidemics
To better understand the impact of national and global efforts to contain the Ebola virus disease epidemic of 2014–15 in Liberia, we provide a detailed timeline of the major interventions and relate them to the epidemic curve. In addition to personal experience in the response, we systematically reviewed situation reports from the Liberian government, UN, CDC, WHO, UNICEF, IFRC, USAID, and local and international news reports to create the timeli…
Improving propensity score weighting using machine learning
Machine learning techniques such as classification and regression trees (CART) have been suggested as promising alternatives to logistic regression for the estimation of propensity scores. The authors examined the performance of various CART‐based propensity score models using simulated data. Hypothetical studies of varying sample sizes ( n =500, 1000, 2000) with a binary exposure, continuous outcome, and 10 covariates were simulated under seven …
Collaborative Hubs
Impact of interventions and the incidence of ebola virus disease in Liberia—implications for future epidemics
To better understand the impact of national and global efforts to contain the Ebola virus disease epidemic of 2014–15 in Liberia, we provide a detailed timeline of the major interventions and relate them to the epidemic curve. In addition to personal experience in the response, we systematically reviewed situation reports from the Liberian government, UN, CDC, WHO, UNICEF, IFRC, USAID, and local and international news reports to create the timeli…
Improving propensity score weighting using machine learning
Machine learning techniques such as classification and regression trees (CART) have been suggested as promising alternatives to logistic regression for the estimation of propensity scores. The authors examined the performance of various CART‐based propensity score models using simulated data. Hypothetical studies of varying sample sizes ( n =500, 1000, 2000) with a binary exposure, continuous outcome, and 10 covariates were simulated under seven …
Impact of interventions and the incidence of ebola virus disease in Liberia—implications for future epidemics
To better understand the impact of national and global efforts to contain the Ebola virus disease epidemic of 2014–15 in Liberia, we provide a detailed timeline of the major interventions and relate them to the epidemic curve. In addition to personal experience in the response, we systematically reviewed situation reports from the Liberian government, UN, CDC, WHO, UNICEF, IFRC, USAID, and local and international news reports to create the timeli…
The Incubation Period of Coronavirus Disease 2019 (Covid-19) From Publicly Reported Confirmed Cases
BACKGROUND: A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incubation period for clinical disease (coronavirus disease 2019 [COVID-19]), which has important implications for surveillance and control activities. OBJECTIVE: To estimate the length of the incubation period of COVID-19 a…
Epidemiology and transmission of Covid-19 in 391 cases and 1286 of their close contacts in Shenzhen, China
Effect of non-pharmaceutical interventions in the early phase of the Covid-19 epidemic in Saudi Arabia
Non-pharmaceutical interventions have been widely employed to control the COVID-19 pandemic. Their associated effect on SARS-CoV-2 transmission have however been unequally studied across regions. Few studies have focused on the Gulf states despite their potential role for global pandemic spread, in particular in the Kingdom of Saudi Arabia through religious pilgrimages. We study the association between NPIs and SARS-CoV-2 transmission in the King…
Collaborative Hubs
Infectious disease surveillance needs for the United States
The COVID-19 pandemic has highlighted the need to upgrade systems for infectious disease surveillance and forecasting and modeling of the spread of infection, both of which inform evidence-based public health guidance and policies. Here, we discuss requirements for an effective surveillance system to support decision making during a pandemic, drawing on the lessons of COVID-19 in the U.S., while looking to jurisdictions in the U.S. and beyond to …
HIV epidemiologic trends among occupational groups in Rakai, Uganda
Certain occupations have been associated with heightened risk of HIV acquisition and spread in sub-Saharan Africa, including female bar and restaurant work and male transportation work. However, data on changes in population prevalence of HIV infection and HIV incidence within occupations following mass scale-up of African HIV treatment and prevention programs is very limited. We evaluated prospective data collected between 1999 and 2016 from the…
Continued T12 transmission and shared antibiotic resistance during 2018–2023 Vibrio cholerae outbreaks in Cameroon
Seventh pandemic Vibrio cholerae was first identified in Cameroon in 1971, causing several sporadic disease clusters with few cases. More recent years have seen larger cholera outbreaks, but the mechanism behind these periodic outbreaks is poorly understood, and it is unclear the degree to which antibiotic resistant strains contribute to disease burden and spread. We used whole genome sequencing to characterize 13 V. cholerae isolates from the 20…
Medicine (9 works) · COVID-19 epidemiological studies (6 works) · Demography (5 works) · Disease (5 works) · Environmental health (5 works) · Computer Science (3 works) · Pandemic (3 works) · Population (3 works) · Sociology (3 works) · Biology (2 works)