David Chien Lye

Dados Biográficos

ID6076387
NOMEDavid Chien Lye
PRENOMESDavid Chien
SOBRENOMELye
ASSINATURALYE D C
AFILIAÇÕESNational University of Singapore
ORCID0000-0003-0324-0205
VERIFICADOSim
TOTAL DE OBRAS6
TOTAL DE CITAÇÕES0
TOTAL COMO AUTOR6
TOTAL COMO EDITOR0
PRIMEIRO ANO DE PUBLICAÇÃO2020
ANO MAIS RECENTE DE PUBLICAÇÃO2024
ÍNDICE H0

  • Hospitalised patients as stewards of their own antibiotic therapy

    Open AccessHuiling Guo, David Chien Lye et al.ARTICLEFrontiers in Public Health2024

  • Multi-dimensional epidemiology and informatics data on Covid-19 wave at the end of zero Covid policy in China

    Open AccessXin-sheng Yu, Shaoying Tan et al.ARTICLEFrontiers in Public Health2024

    Background: China exited strict Zero-COVID policy with a surge in Omicron variant infections in December 2022. Given China's pandemic policy and population immunity, employing Baidu Index (BDI) to analyze the evolving disease landscape and estimate the nationwide pneumonia hospitalizations in the post Zero COVID period, validated by hospital data, holds informative potential for future outbreaks. Methods: Retrospective observational analyses were…

  • Feasibility of wastewater-based detection of emergent pandemics through a global network of airports

    Open AccessShihui Jin, Borame Sue Lee Dickens et al.ARTICLEPLOS Global Public Health2024

    Wastewater-based surveillance has been put into practice during the pandemic. Persistence of SARS-CoV-2 in faeces of infected individuals, and high volume of passengers travelling by air, make it possible to detect virus from aircraft wastewater, lending itself to the potential identification of a novel pathogen prior to clinical diagnosis. In this study, we estimated the likelihood of detecting the virus through aircraft wastewater from the prob…

  • Estimating the economic cost of carbapenem resistant Enterobacterales healthcare associated infections in Singapore acute-care hospitals

    Open AccessYiying Cai, Grace Si Ru Hoo et al.ARTICLEPLOS Global Public Health2022

    Quantifying the costs of hospital associated infections (HAIs) caused by carbapenem-resistant Enterobacterales (CRE) can aid hospital decision makers in infection prevention and control decisions. We estimate the costs of a CRE HAI by infection type and the annual costs of CRE HAIs to acute-care hospitals in Singapore. We used tree diagrams to estimate the costs (in Singapore dollar) of different CRE HAI types from the health service perspective …

  • Remdesivir for the Treatment of Covid-19 — Final Report

    Open AccessJohn H Beigel, Kay M Tomashek et al.ARTICLENew England Journal of Medicine2020

    BACKGROUND: Although several therapeutic agents have been evaluated for the treatment of coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be efficacious. METHODS: We conducted a double-blind, randomized, placebo-controlled trial of intravenous remdesivir in adults who were hospitalized with Covid-19 and had evidence of lower respiratory tract infection. Patients were randomly assigned to receive either remdesivir (2…

  • Outbreak of Measles in a Residential Home for the Intellectually Disabled in Singapore in 2019

    Valerie T J Koh, Calvin J Chiew et al.ARTICLEAmerican Journal of Public Health2020Referências: 2

    A measles outbreak involving 19 adults in a home for the intellectually disabled occurred in Singapore in 2019. Further investigation, including a serological survey, was conducted. Mass vaccination and infection control measures were implemented, terminating further secondary transmission. Seropositivity among residents aged 40 to 49 years (90.7%; 95% confidence interval = 78.4%, 96.3%) was lower than among the Singapore adult population (P