S G Wannamethee
Biographic Data
| ID | 6077504 |
|---|---|
| NAME | S G Wannamethee |
| GIVEN NAMES | S G |
| FAMILY NAME | Wannamethee |
| SIGNATURE | WANNAMETHEE S G |
| AFFILIATIONS | Department of Primary Care and Population Health, University College London (UCL), London, UK |
| VERIFIED | No |
| TOTAL WORKS | 13 |
| TOTAL CITATIONS | 20 |
| WORKS AS AUTHOR | 13 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1994 |
| LATEST PUBLICATION YEAR | 2015 |
| H-INDEX | 3 |
The influence of neighbourhood-level socioeconomic deprivation on cardiovascular disease mortality in older age
BACKGROUND: Evidence from longitudinal studies on the influence of neighbourhood socioeconomic factors in older age on cardiovascular disease (CVD) mortality is limited. We aimed to investigate the prospective association of neighbourhood-level deprivation in later life with CVD mortality, and assess the underlying role of established cardiovascular risk factors. METHODS: A socially representative cohort of 3924 men, aged 60-79 years in 1998-2000…
OP86 Dietary Patterns in Older Men
Background Few studies have examined diet quality in older adults in Great Britain. We examined the influence of area of residence and early life social circumstances on dietary patterns among older British men. Methods We conducted a cross-sectional study of 4252 older men (aged 60-79 years) from the British Regional Heart Study. Food frequency questionnaire data were used to examine daily fruit and vegetable consumption and to generate two diet…
OP80 Inequalities in Heart Failure in Older Age
Background Few studies have examined the prospective associations between socioeconomic measures and incident heart failure, and little is known about possible mechanisms underlying the relationship. The aim of this study was to investigate the association of socioeconomic measures with incident heart failure in older adults and to examine possible underlying pathways. Methods A socially and geographically representative cohort of men aged 60–79 …
Is the recent rise in type 2 diabetes mellitus incidence from 1984 to 2007 explained by the trend in increasing body mass index? Evidence from a prospective study of British men
Objective Incidence of type 2 diabetes mellitus (T2DM) in the UK has increased by two-thirds in the last decade. Understanding the reasons for the unfavourable trend may help inform efforts to curb future increases. The association between T2DM and adiposity has been established. However, few attempts have been made to quantify the contribution of adiposity changes to the observed time trend in T2DM. We estimated the proportion of the time trend …
Have socio-economic differences in coronary risk factors changed over 20 years? Results from a population-based study of men between 1978–1980 and 1998–2000
Background Although CHD mortality has declined in the UK since the late 1970s, the decline has been particularly marked among more affluent subjects. While the decline substantially reflects improvements in established coronary risk factors, little is known about how these have changed in different socio-economic groups. Objective To examine whether socio-economic differences in coronary risk factors in Britain have changed over 20 years between …
Secondhand smoke exposure assessed using serum cotinine
The trial is challenging, both in terms of recruitment, and motivating behaviour change. The presentation will elaborate on the recruitment experience into a trial evaluating the effectiveness of interventions in ethnic minority populations
Comparison of the associations of BMI and measures of regional adiposity with coronary heart disease, diabetes and all cause mortality
Objective: To compare magnitudes of association of BMI and measures of regional adiposity with coronary heart disease, diabetes and all-cause mortality. Design: 2 prospective cohort and 2 cross sectional studies. Participants: Members of 4 UK cohorts aged >45 years: 3937 women from the British Women's Heart and Health Study (BWHHS), 2367 and 1950 men from phases 1 and 3 of the Caerphilly Prospective Study (CaPS), 403 men and women from Boyd Orr, …
Year trends in major coronary risk factors in older British men
the ''drift''. Our predictions are that stroke deaths are likely to continue to decrease up to at least 2015. For 2015, our predictions of deaths from stroke varied from 34 429 to 46 538 (compared with 47 213 deaths in 2005) under the different plausible model scenarios. We also noted that there were some potentially interesting trends in mortality amongst recent birth cohorts. In particular, mortality was higher in older age groups, but the diff…
Prediction scores to identify older adults at high risk for type 2 diabetes
The greatest relative increase in type 2 diabetes (T2DM) prevalence in developed countries thought likely to occur over the next 25 years will be in the over 65 age group. The aim of this study was to examine the effectiveness of both simple strategies based on simple clinical parameters (suitable for use in primary care) and more complex scores involving blood markers to identify older individuals at high risk of developing T2DM. A
Are social inequalities in mortality in Britain narrowing? Time trends from 1978 to 2005 in a population-based study of older men
OBJECTIVE: To examine whether social inequalities in all-cause and coronary heart disease (CHD) mortality in Britain have reduced between 1978 and 2005. DESIGN: A prospective study of a socioeconomically representative population. SETTING: 24 British towns. PARTICIPANTS: 7735 Men, aged 40-59 years at recruitment in 1978-1980 and followed up until 2005 through the National Health Service Central Register (164 120 person-years). MAIN OUTCOME MEASUR…
Alcohol consumption and the incidence of type II diabetes
Background: This study examines the relation between alcohol and type II diabetes and the possible mediating effects of HDL-cholesterol and serum insulin. Methods: Prospective study of 5221 men aged 40–59 years with no history of coronary heart disease, diabetes, or stroke drawn from general practices in 18 British towns. Results: During the mean follow up of 16.8 years there were 198 incident cases of type II diabetes. Occasional drinkers were t…
Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality
OBJECTIVES: This study examined the effects of beer, spirits, and wine drinking on coronary heart disease (CHD) events (fatal and nonfatal) and all-cause mortality. METHODS: Men aged 40 to 59 years (n = 7735) were drawn at random from one general practice in each of 24 British towns and followed up for an average of 16.8 years. RESULTS: Regular drinkers showed a significantly lower relative risk of CHD, but no all-cause mortality, than occasional…
Asymptomatic hyperglycaemia and major ischaemic heart disease events in Britain
OBJECTIVE--To examine the association between non-fasting serum glucose concentrations and major ischaemic heart disease (IHD) events (fatal and non-fatal myocardial infarction). DESIGN--A prospective study. SUBJECTS--A population based sample of 7735 middle aged British men. Known diabetics, men with a glucose concentration > or = 11.1 mmol/l at screening, and hypertensive patients taking regular medication were excluded from the analysis. With …
Alcohol consumption and the incidence of type II diabetes
Background: This study examines the relation between alcohol and type II diabetes and the possible mediating effects of HDL-cholesterol and serum insulin. Methods: Prospective study of 5221 men aged 40–59 years with no history of coronary heart disease, diabetes, or stroke drawn from general practices in 18 British towns. Results: During the mean follow up of 16.8 years there were 198 incident cases of type II diabetes. Occasional drinkers were t…
Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality
OBJECTIVES: This study examined the effects of beer, spirits, and wine drinking on coronary heart disease (CHD) events (fatal and nonfatal) and all-cause mortality. METHODS: Men aged 40 to 59 years (n = 7735) were drawn at random from one general practice in each of 24 British towns and followed up for an average of 16.8 years. RESULTS: Regular drinkers showed a significantly lower relative risk of CHD, but no all-cause mortality, than occasional…
Are social inequalities in mortality in Britain narrowing? Time trends from 1978 to 2005 in a population-based study of older men
OBJECTIVE: To examine whether social inequalities in all-cause and coronary heart disease (CHD) mortality in Britain have reduced between 1978 and 2005. DESIGN: A prospective study of a socioeconomically representative population. SETTING: 24 British towns. PARTICIPANTS: 7735 Men, aged 40-59 years at recruitment in 1978-1980 and followed up until 2005 through the National Health Service Central Register (164 120 person-years). MAIN OUTCOME MEASUR…
The influence of neighbourhood-level socioeconomic deprivation on cardiovascular disease mortality in older age
BACKGROUND: Evidence from longitudinal studies on the influence of neighbourhood socioeconomic factors in older age on cardiovascular disease (CVD) mortality is limited. We aimed to investigate the prospective association of neighbourhood-level deprivation in later life with CVD mortality, and assess the underlying role of established cardiovascular risk factors. METHODS: A socially representative cohort of 3924 men, aged 60-79 years in 1998-2000…
Asymptomatic hyperglycaemia and major ischaemic heart disease events in Britain
OBJECTIVE--To examine the association between non-fasting serum glucose concentrations and major ischaemic heart disease (IHD) events (fatal and non-fatal myocardial infarction). DESIGN--A prospective study. SUBJECTS--A population based sample of 7735 middle aged British men. Known diabetics, men with a glucose concentration > or = 11.1 mmol/l at screening, and hypertensive patients taking regular medication were excluded from the analysis. With …
Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality
OBJECTIVES: This study examined the effects of beer, spirits, and wine drinking on coronary heart disease (CHD) events (fatal and nonfatal) and all-cause mortality. METHODS: Men aged 40 to 59 years (n = 7735) were drawn at random from one general practice in each of 24 British towns and followed up for an average of 16.8 years. RESULTS: Regular drinkers showed a significantly lower relative risk of CHD, but no all-cause mortality, than occasional…
Alcohol consumption and the incidence of type II diabetes
Background: This study examines the relation between alcohol and type II diabetes and the possible mediating effects of HDL-cholesterol and serum insulin. Methods: Prospective study of 5221 men aged 40–59 years with no history of coronary heart disease, diabetes, or stroke drawn from general practices in 18 British towns. Results: During the mean follow up of 16.8 years there were 198 incident cases of type II diabetes. Occasional drinkers were t…
Are social inequalities in mortality in Britain narrowing? Time trends from 1978 to 2005 in a population-based study of older men
OBJECTIVE: To examine whether social inequalities in all-cause and coronary heart disease (CHD) mortality in Britain have reduced between 1978 and 2005. DESIGN: A prospective study of a socioeconomically representative population. SETTING: 24 British towns. PARTICIPANTS: 7735 Men, aged 40-59 years at recruitment in 1978-1980 and followed up until 2005 through the National Health Service Central Register (164 120 person-years). MAIN OUTCOME MEASUR…
Secondhand smoke exposure assessed using serum cotinine
The trial is challenging, both in terms of recruitment, and motivating behaviour change. The presentation will elaborate on the recruitment experience into a trial evaluating the effectiveness of interventions in ethnic minority populations
Comparison of the associations of BMI and measures of regional adiposity with coronary heart disease, diabetes and all cause mortality
Objective: To compare magnitudes of association of BMI and measures of regional adiposity with coronary heart disease, diabetes and all-cause mortality. Design: 2 prospective cohort and 2 cross sectional studies. Participants: Members of 4 UK cohorts aged >45 years: 3937 women from the British Women's Heart and Health Study (BWHHS), 2367 and 1950 men from phases 1 and 3 of the Caerphilly Prospective Study (CaPS), 403 men and women from Boyd Orr, …
Year trends in major coronary risk factors in older British men
the ''drift''. Our predictions are that stroke deaths are likely to continue to decrease up to at least 2015. For 2015, our predictions of deaths from stroke varied from 34 429 to 46 538 (compared with 47 213 deaths in 2005) under the different plausible model scenarios. We also noted that there were some potentially interesting trends in mortality amongst recent birth cohorts. In particular, mortality was higher in older age groups, but the diff…
Prediction scores to identify older adults at high risk for type 2 diabetes
The greatest relative increase in type 2 diabetes (T2DM) prevalence in developed countries thought likely to occur over the next 25 years will be in the over 65 age group. The aim of this study was to examine the effectiveness of both simple strategies based on simple clinical parameters (suitable for use in primary care) and more complex scores involving blood markers to identify older individuals at high risk of developing T2DM. A
Is the recent rise in type 2 diabetes mellitus incidence from 1984 to 2007 explained by the trend in increasing body mass index? Evidence from a prospective study of British men
Objective Incidence of type 2 diabetes mellitus (T2DM) in the UK has increased by two-thirds in the last decade. Understanding the reasons for the unfavourable trend may help inform efforts to curb future increases. The association between T2DM and adiposity has been established. However, few attempts have been made to quantify the contribution of adiposity changes to the observed time trend in T2DM. We estimated the proportion of the time trend …
Have socio-economic differences in coronary risk factors changed over 20 years? Results from a population-based study of men between 1978–1980 and 1998–2000
Background Although CHD mortality has declined in the UK since the late 1970s, the decline has been particularly marked among more affluent subjects. While the decline substantially reflects improvements in established coronary risk factors, little is known about how these have changed in different socio-economic groups. Objective To examine whether socio-economic differences in coronary risk factors in Britain have changed over 20 years between …
OP86 Dietary Patterns in Older Men
Background Few studies have examined diet quality in older adults in Great Britain. We examined the influence of area of residence and early life social circumstances on dietary patterns among older British men. Methods We conducted a cross-sectional study of 4252 older men (aged 60-79 years) from the British Regional Heart Study. Food frequency questionnaire data were used to examine daily fruit and vegetable consumption and to generate two diet…
OP80 Inequalities in Heart Failure in Older Age
Background Few studies have examined the prospective associations between socioeconomic measures and incident heart failure, and little is known about possible mechanisms underlying the relationship. The aim of this study was to investigate the association of socioeconomic measures with incident heart failure in older adults and to examine possible underlying pathways. Methods A socially and geographically representative cohort of men aged 60–79 …
The influence of neighbourhood-level socioeconomic deprivation on cardiovascular disease mortality in older age
BACKGROUND: Evidence from longitudinal studies on the influence of neighbourhood socioeconomic factors in older age on cardiovascular disease (CVD) mortality is limited. We aimed to investigate the prospective association of neighbourhood-level deprivation in later life with CVD mortality, and assess the underlying role of established cardiovascular risk factors. METHODS: A socially representative cohort of 3924 men, aged 60-79 years in 1998-2000…
Medicine (13 works) · Internal Medicine (12 works) · Internal Medicine (12 works) · Gerontology (9 works) · Gerontology (9 works) · Demography (8 works) · Environmental health (8 works) · Body mass index (7 works) · Confidence interval (6 works) · Population (6 works)