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Jaap M Koolhaas

Biographic Data

ID6109586
NAMEJaap M Koolhaas
GIVEN NAMESJaap M
FAMILY NAMEKoolhaas
SIGNATUREKOOLHAAS J M
AFFILIATIONSUniversity of Groningen
VERIFIEDNo
TOTAL WORKS11
TOTAL CITATIONS2
WORKS AS AUTHOR11
WORKS AS EDITOR0
FIRST PUBLICATION YEAR1983
LATEST PUBLICATION YEAR2014
H-INDEX1
  • Aggression and aspects of impulsivity in wild‐type rats

    Open Access•Caroline M Coppens, Sietse F de Boer et al.•ARTICLE•Aggressive Behavior•2014•References: 53

    Aggression is closely related to impulsive behavior both in humans and in animals. To avoid potential negative consequences, aggressive behavior is kept in control by strong inhibitory mechanisms. Failure of these inhibitory mechanisms results in violent behavior. In the present experiments, we investigated whether aggressive behavior is related to impulsive behavior. Furthermore, we investigated if violent behavior can be distinguished from "nor…

  • Structural and Electrical Myocardial Remodeling in a Rodent Model of Depression

    Luca Carnevali, Mimosa Trombini et al.•ARTICLE•Psychosomatic Medicine•2013

    OBJECTIVE: Despite a well-documented association between stress and depression with cardiac morbidity and mortality, there is no satisfactory explanation for the mechanisms linking affective and cardiac disorders. This study investigated cardiac electrophysiological properties in an animal model of depression. METHODS: Depression-relevant physiological and behavioral parameters were measured in adult male wild-type rats during and after a period …

  • Poor sleep as a potential causal factor in aggression and violence

    Open Access•Jeanine Kamphuis, Peter Meerlo et al.•ARTICLE•Sleep Medicine•2012

  • Stress revisited

    Open Access•Jaap M Koolhaas, Alessandro Bartolomucci et al.•ARTICLE•Neuroscience & Biobehavioral…•2011

  • Violent phenotype in SAL mice is inflexible and fixed in adulthood

    Open Access•Deepa Natarajan, Han De Vries et al.•ARTICLE•Aggressive Behavior•2009•Cited by: 2•References: 14

    Violence was shown to be qualitatively different from functional hyper‐aggression in mice selected for high aggression namely Short Attack Latency (SAL), Turku Aggressive (TA) and North Carolina (NC900) strains. This study aimed at investigating whether this adulthood violent phenotype as seen previously in the SAL mice is fixed and hence behaviorally inflexible right from day 1 of the experiment or consequential , i.e., subject to gradual change…

  • Strain‐specific aggressive behavior of male mice submitted to different husbandry procedures

    Open Access•P L P Van Loo, E Van der Meer et al.•ARTICLE•Aggressive Behavior•2003•References: 36

    Severe aggression within groups of male laboratory mice can cause serious welfare problems. Previous experiments have shown that the transfer of specific olfactory cues during cage cleaning and the provision of nesting material decrease aggression and stress in group‐housed male mice. In this study, the combined effect of these husbandry procedures was tested for their long‐term effect on aggression in two strains of male mice (BALB/c and CD‐1). …

  • Acute social stress and cardiac electrical activity in rats

    Open Access•Andrea Sgoifo, Donatella Stilli et al.•ARTICLE•Aggressive Behavior•1998•References: 34

    This paper summarizes the results of experiments aimed at describing electrocardiographic responses to different acute social stressors in healthy male rats. Electrocardiograms were telemetrically recorded during maternal aggression, social defeat, and psychosocial stimulation, as obtained using the classical resident-intruder paradigm. Autonomic input to the heart was indirectly evaluated by means of heart rate variability measures and plasma ca…

  • Studies on wild house mice VI

    Open Access•Frans Sluyter, Geert A van Oortmerssen et al.•ARTICLE•Aggressive Behavior•1994•References: 15

    The aim of this study is to determine the effects of different parts of the Y chromosome of wild house mice on aggression. To reach this goal, intercrosses were made between two selection lines for attack latency (SAL and LAL) and their congenic strains (SAL. LY and LAL. SY). This procedure resulted in F1 hybrids that carried the same autosomes, but differed in their X chromosome and the two different parts of their Y chromosomes, the different p…

  • Differential testosterone secretory capacity of the testes of aggressive and nonaggressive house mice during ontogeny

    Open Access•Anne J H de Ruiter, Jaap M Koolhaas et al.•ARTICLE•Aggressive Behavior•1992•References: 36

    In this study, testosterone secretory capacity of testicular Leydig cells during ontogeny was determined in males of an aggressive and a nonaggressive genetic selection line of wild house mice. Neonates, 23-day-old prepubertals, and adult male mice were studied. A morphometric method was used to quantify 3β-hydroxy steroid dehydrogenase (3β-3HSD)-stained Leydig cells in testicular sections to determine testosterone secretory capacity. We consider…

  • Medial amygdala and aggressive behavior

    Open Access•Jaap M Koolhaas, T H C Van Den Brink et al.•ARTICLE•Aggressive Behavior•1990•References: 22

    This paper considers the functional significance of the testosterone-dependent vasopressinergic neurons of the medial amygdala (Ame) in intermale aggressive behavior of rats. Local microinfusion of vasopressin into the medial amygdala causes an increase in offensive behavior both in gonadally intact males and in animals that were castrated 1 week or 6 months prior to the experiment. The absolute level of offense after arginine-vasopressin (AVP) t…

  • The nucleus premammillaris ventralis (pmv) and aggressive behavior in the rat

    Open Access•M J Den Van Berg, MP Berg et al.•ARTICLE•Aggressive Behavior•1983•References: 17

    Small bilateral electrolytic lesions placed just posterior of the ventromedial hypothalamic nucleus cause a strong increase in offensive behavior. The histology suggests that damage to the ventral premanimillary nucleus is responsible for this effect. A summary of the neuroanatomical literature shows that this structure is connected to most other brain structures reported to be involved in offensive behavior.

  • Violent phenotype in SAL mice is inflexible and fixed in adulthood

    Open Access•Deepa Natarajan, Han De Vries et al.•ARTICLE•Aggressive Behavior•2009•Cited by: 2•References: 14

    Violence was shown to be qualitatively different from functional hyper‐aggression in mice selected for high aggression namely Short Attack Latency (SAL), Turku Aggressive (TA) and North Carolina (NC900) strains. This study aimed at investigating whether this adulthood violent phenotype as seen previously in the SAL mice is fixed and hence behaviorally inflexible right from day 1 of the experiment or consequential , i.e., subject to gradual change…

  • The nucleus premammillaris ventralis (pmv) and aggressive behavior in the rat

    Open Access•M J Den Van Berg, MP Berg et al.•ARTICLE•Aggressive Behavior•1983•References: 17

    Small bilateral electrolytic lesions placed just posterior of the ventromedial hypothalamic nucleus cause a strong increase in offensive behavior. The histology suggests that damage to the ventral premanimillary nucleus is responsible for this effect. A summary of the neuroanatomical literature shows that this structure is connected to most other brain structures reported to be involved in offensive behavior.

  • Medial amygdala and aggressive behavior

    Open Access•Jaap M Koolhaas, T H C Van Den Brink et al.•ARTICLE•Aggressive Behavior•1990•References: 22

    This paper considers the functional significance of the testosterone-dependent vasopressinergic neurons of the medial amygdala (Ame) in intermale aggressive behavior of rats. Local microinfusion of vasopressin into the medial amygdala causes an increase in offensive behavior both in gonadally intact males and in animals that were castrated 1 week or 6 months prior to the experiment. The absolute level of offense after arginine-vasopressin (AVP) t…

  • Differential testosterone secretory capacity of the testes of aggressive and nonaggressive house mice during ontogeny

    Open Access•Anne J H de Ruiter, Jaap M Koolhaas et al.•ARTICLE•Aggressive Behavior•1992•References: 36

    In this study, testosterone secretory capacity of testicular Leydig cells during ontogeny was determined in males of an aggressive and a nonaggressive genetic selection line of wild house mice. Neonates, 23-day-old prepubertals, and adult male mice were studied. A morphometric method was used to quantify 3β-hydroxy steroid dehydrogenase (3β-3HSD)-stained Leydig cells in testicular sections to determine testosterone secretory capacity. We consider…

  • Studies on wild house mice VI

    Open Access•Frans Sluyter, Geert A van Oortmerssen et al.•ARTICLE•Aggressive Behavior•1994•References: 15

    The aim of this study is to determine the effects of different parts of the Y chromosome of wild house mice on aggression. To reach this goal, intercrosses were made between two selection lines for attack latency (SAL and LAL) and their congenic strains (SAL. LY and LAL. SY). This procedure resulted in F1 hybrids that carried the same autosomes, but differed in their X chromosome and the two different parts of their Y chromosomes, the different p…

  • Acute social stress and cardiac electrical activity in rats

    Open Access•Andrea Sgoifo, Donatella Stilli et al.•ARTICLE•Aggressive Behavior•1998•References: 34

    This paper summarizes the results of experiments aimed at describing electrocardiographic responses to different acute social stressors in healthy male rats. Electrocardiograms were telemetrically recorded during maternal aggression, social defeat, and psychosocial stimulation, as obtained using the classical resident-intruder paradigm. Autonomic input to the heart was indirectly evaluated by means of heart rate variability measures and plasma ca…

  • Strain‐specific aggressive behavior of male mice submitted to different husbandry procedures

    Open Access•P L P Van Loo, E Van der Meer et al.•ARTICLE•Aggressive Behavior•2003•References: 36

    Severe aggression within groups of male laboratory mice can cause serious welfare problems. Previous experiments have shown that the transfer of specific olfactory cues during cage cleaning and the provision of nesting material decrease aggression and stress in group‐housed male mice. In this study, the combined effect of these husbandry procedures was tested for their long‐term effect on aggression in two strains of male mice (BALB/c and CD‐1). …

  • Violent phenotype in SAL mice is inflexible and fixed in adulthood

    Open Access•Deepa Natarajan, Han De Vries et al.•ARTICLE•Aggressive Behavior•2009•Cited by: 2•References: 14

    Violence was shown to be qualitatively different from functional hyper‐aggression in mice selected for high aggression namely Short Attack Latency (SAL), Turku Aggressive (TA) and North Carolina (NC900) strains. This study aimed at investigating whether this adulthood violent phenotype as seen previously in the SAL mice is fixed and hence behaviorally inflexible right from day 1 of the experiment or consequential , i.e., subject to gradual change…

  • Stress revisited

    Open Access•Jaap M Koolhaas, Alessandro Bartolomucci et al.•ARTICLE•Neuroscience & Biobehavioral…•2011

  • Poor sleep as a potential causal factor in aggression and violence

    Open Access•Jeanine Kamphuis, Peter Meerlo et al.•ARTICLE•Sleep Medicine•2012

  • Structural and Electrical Myocardial Remodeling in a Rodent Model of Depression

    Luca Carnevali, Mimosa Trombini et al.•ARTICLE•Psychosomatic Medicine•2013

    OBJECTIVE: Despite a well-documented association between stress and depression with cardiac morbidity and mortality, there is no satisfactory explanation for the mechanisms linking affective and cardiac disorders. This study investigated cardiac electrophysiological properties in an animal model of depression. METHODS: Depression-relevant physiological and behavioral parameters were measured in adult male wild-type rats during and after a period …

  • Aggression and aspects of impulsivity in wild‐type rats

    Open Access•Caroline M Coppens, Sietse F de Boer et al.•ARTICLE•Aggressive Behavior•2014•References: 53

    Aggression is closely related to impulsive behavior both in humans and in animals. To avoid potential negative consequences, aggressive behavior is kept in control by strong inhibitory mechanisms. Failure of these inhibitory mechanisms results in violent behavior. In the present experiments, we investigated whether aggressive behavior is related to impulsive behavior. Furthermore, we investigated if violent behavior can be distinguished from "nor…

Medicine (9 works) · Psychology (9 works) · Aggression (7 works) · Developmental psychology (7 works) · Stress Responses and Cortisol (7 works) · Neuroendocrine regulation and behavior (6 works) · Biology (5 works) · Endocrinology (4 works) · Internal Medicine (4 works) · Neuroscience (3 works)

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