Waasila Jassat
Dados Biográficos
| ID | 6161606 |
|---|---|
| NOME | Waasila Jassat |
| PRENOMES | Waasila |
| SOBRENOME | Jassat |
| ASSINATURA | JASSAT W |
| AFILIAÇÕES | National Health Laboratory Service |
| ORCID | 0000-0003-4279-3056 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 16 |
| TOTAL DE CITAÇÕES | 3 |
| TOTAL COMO AUTOR | 16 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2009 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 1 |
Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa
Several tuberculosis (TB) vaccines intended for adults and adolescents are in late-stage clinical trials, but there is limited research into how a new TB vaccine would be introduced. South Africa is at the forefront of TB vaccine research, with involvement in the clinical trials of leading candidates. We sought to understand what the priorities and implementation approach of a potential new TB vaccine in South Africa would be. We conducted semi-s…
Actor sensemaking and its role in implementation of the decentralized drug-resistant tuberculosis policy in South Africa
South Africa has a high burden of drug-resistant tuberculosis (DR-TB). A policy to decentralize DR-TB treatment from specialized central hospitals to more accessible district facilities was introduced in 2011, but to date implementation has been suboptimal, with variable pace, coverage, and models of care emerging. This study explored multilevel policy implementation of DR-TB decentralization in two provinces of South Africa, Western Cape and Kwa…
Long Covid
INTRODUCTION: A proportion of people develop Long Covid after acute COVID-19, but with most studies concentrated in high-income countries (HICs), the global burden is largely unknown. Our study aims to characterise long-term COVID-19 sequelae in populations globally and compare the prevalence of reported symptoms in HICs and low-income and middle-income countries (LMICs). METHODS: A prospective, observational study in 17 countries in Africa, Asia…
Safety, effectiveness and immunogenicity of heterologous mRNA-1273 boost after prime with Ad26.COV2.S among healthcare workers in South Africa
Limited studies have been conducted on the safety and effectiveness of heterologous COVID-19 vaccine boosting in lower income settings, especially those with high-HIV prevalence., The Sisonke Heterologous mRNA-1273 boost after prime with Ad26.COV2.S (SHERPA) trial evaluated a mRNA-1273 boost after Ad26.COV2.S priming in South Africa. SHERPA was a single-arm, open-label, phase 3 study nested in the Sisonke implementation trial of 500000 healthcare…
The association of Sars-CoV-2 infection and tuberculosis disease with unfavorable treatment outcomes
Background Whether SARS-CoV-2 infection and its management influence tuberculosis (TB) treatment outcomes is uncertain. We synthesized evidence on the association of SARS-CoV-2 coinfection ( Coinfection Review ) and its management ( Clinical Management Review ) on treatment outcomes among people with tuberculosis (TB) disease. Methods We systematically searched the literature from 1 January 2020 to 6 February 2022. Primary outcomes included: unfa…
Differential in-hospital mortality and intensive care treatment over time
There are limited published data within sub-Saharan Africa describing hospital pathways of COVID-19 patients hospitalized. These data are crucial for the parameterisation of epidemiological and cost models, and for planning purposes for the region. We evaluated COVID-19 hospital admissions from the South African national hospital surveillance system (DATCOV) during the first three COVID-19 waves between May 2020 and August 2021. We describe proba…
Using generalized structured additive regression models to determine factors associated with and clusters for Covid-19 hospital deaths in South Africa
The results show substantial COVID-19 in-hospital mortality variation across the 52 districts. Our analysis provides information that can be important for strengthening health policies and the public health system for the benefit of the whole South African population. Understanding differences in in-hospital COVID-19 mortality across space could guide interventions to achieve better health outcomes in affected districts
The role of emergent champions in policy implementation for decentralised drug-resistant tuberculosis care in South Africa
OBJECTIVE: Champions are recognised as important to driving organisational change in healthcare quality improvement initiatives in high-income settings. In low-income and middle-income countries with a high disease burden and constrained human resources, their role is highly relevant yet understudied. Within a broader study on policy implementation for decentralised drug-resistant tuberculosis care in South Africa, we characterised the role, stra…
Disease Severity and Comorbidities among Healthcare Worker Covid-19 Admissions in South Africa
Healthcare workers (HCWs) are among the most vulnerable in regard to contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Comorbidities are reported to increase the risk for more severe COVID-19 outcomes, often requiring hospitalization. However, the evidence on disease severity and comorbidities among South African HCWs is lacking. This retrospective study analyzed the prevalence of comorbidities among HCW hospital…
Sars-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa
The analysis of SARS-CoV-2 cases in sentinel LTCFs in South Africa points to an encouraging trend of decreasing numbers of outbreaks, cases and risk for mortality since the first wave. LTCFs are likely to have learnt from international experience and adopted national protocols, which include improved measures to limit transmission and administer early and appropriate clinical care
We had to manage what we had on hand, in whatever way we could’
In 2011, the South African National TB Programme launched a policy of decentralized management of drug-resistant tuberculosis (DR-TB) in order to expand the capacity of facilities to treat patients with DR-TB, minimize delays to access care and improve patient outcomes. This policy directive was implemented to varying degrees within a rapidly evolving diagnostic and treatment landscape for DR-TB, placing new demands on already-stressed health sys…
Executive Summaries
This article describes the roles of five advocacy groups that built collaborative initiatives to address the collapsing health care system in South Africa. Findings indicate that for both advocacy groups working in alliances and for funders, flexible funding and a shared value system among groups with diverse capacities, constituencies, and reputational resources are keys to enabling adaptive and innovative strategies for holding the public secto…
Enhancing Funders’ and Advocates’ Effectiveness
This article describes the roles of five advocacy groups that built collaborative initiatives to address the collapsing health system in South Africa. The findings presented are based on retrospective reviews of annual reports, organizational evaluations, interviews, and focus group discussions with each of four participating organizations and existing literature on the fifth. The key findings, for both advocacy groups shaping alliance strategies…
Supplementary immunization activities (SIAs) in South Africa
BACKGROUND: Supplementary immunization activity (SIA) campaigns provide children with an additional dose of measles vaccine and deliver other interventions, including vitamin A supplements, deworming medications, and oral polio vaccines. OBJECTIVE: To assess the cost-effectiveness of the full SIA delivery platform in South Africa (SA). DESIGN: We used an epidemiologic cost model to estimate the cost-effectiveness of the 2010 SIA campaign. We used…
Impact of supplemental immunisation activity (SIA) campaigns on health systems
BACKGROUND: Supplemental immunisation activity (SIA) campaigns provide children with an additional dose of measles vaccine and deliver other child health interventions including vitamin A supplements, deworming medications and oral polio vaccines. They also require the mobilisation of a large health workforce. We assess the impact of the implementation of SIA campaigns on selected routine child and maternal health services in South Africa (SA). M…
How to stop public health conferences becoming trade fairs
Reflecting the new wave of global public health, which now seems to be finally reoriented towards embracing its social mission and responsibilities, the 12th World Congress on Public Health, recently held in Istanbul, dedicated many of its sessions to ethics and the right to health. Indeed, the Congress title, 'Making a Difference in Global Public Health: Education, Research and Practice', sounded like a call to action. But faultless theory and s…
Impact of supplemental immunisation activity (SIA) campaigns on health systems
BACKGROUND: Supplemental immunisation activity (SIA) campaigns provide children with an additional dose of measles vaccine and deliver other child health interventions including vitamin A supplements, deworming medications and oral polio vaccines. They also require the mobilisation of a large health workforce. We assess the impact of the implementation of SIA campaigns on selected routine child and maternal health services in South Africa (SA). M…
How to stop public health conferences becoming trade fairs
Reflecting the new wave of global public health, which now seems to be finally reoriented towards embracing its social mission and responsibilities, the 12th World Congress on Public Health, recently held in Istanbul, dedicated many of its sessions to ethics and the right to health. Indeed, the Congress title, 'Making a Difference in Global Public Health: Education, Research and Practice', sounded like a call to action. But faultless theory and s…
Supplementary immunization activities (SIAs) in South Africa
BACKGROUND: Supplementary immunization activity (SIA) campaigns provide children with an additional dose of measles vaccine and deliver other interventions, including vitamin A supplements, deworming medications, and oral polio vaccines. OBJECTIVE: To assess the cost-effectiveness of the full SIA delivery platform in South Africa (SA). DESIGN: We used an epidemiologic cost model to estimate the cost-effectiveness of the 2010 SIA campaign. We used…
Impact of supplemental immunisation activity (SIA) campaigns on health systems
BACKGROUND: Supplemental immunisation activity (SIA) campaigns provide children with an additional dose of measles vaccine and deliver other child health interventions including vitamin A supplements, deworming medications and oral polio vaccines. They also require the mobilisation of a large health workforce. We assess the impact of the implementation of SIA campaigns on selected routine child and maternal health services in South Africa (SA). M…
Executive Summaries
This article describes the roles of five advocacy groups that built collaborative initiatives to address the collapsing health care system in South Africa. Findings indicate that for both advocacy groups working in alliances and for funders, flexible funding and a shared value system among groups with diverse capacities, constituencies, and reputational resources are keys to enabling adaptive and innovative strategies for holding the public secto…
Enhancing Funders’ and Advocates’ Effectiveness
This article describes the roles of five advocacy groups that built collaborative initiatives to address the collapsing health system in South Africa. The findings presented are based on retrospective reviews of annual reports, organizational evaluations, interviews, and focus group discussions with each of four participating organizations and existing literature on the fifth. The key findings, for both advocacy groups shaping alliance strategies…
We had to manage what we had on hand, in whatever way we could’
In 2011, the South African National TB Programme launched a policy of decentralized management of drug-resistant tuberculosis (DR-TB) in order to expand the capacity of facilities to treat patients with DR-TB, minimize delays to access care and improve patient outcomes. This policy directive was implemented to varying degrees within a rapidly evolving diagnostic and treatment landscape for DR-TB, placing new demands on already-stressed health sys…
The role of emergent champions in policy implementation for decentralised drug-resistant tuberculosis care in South Africa
OBJECTIVE: Champions are recognised as important to driving organisational change in healthcare quality improvement initiatives in high-income settings. In low-income and middle-income countries with a high disease burden and constrained human resources, their role is highly relevant yet understudied. Within a broader study on policy implementation for decentralised drug-resistant tuberculosis care in South Africa, we characterised the role, stra…
Disease Severity and Comorbidities among Healthcare Worker Covid-19 Admissions in South Africa
Healthcare workers (HCWs) are among the most vulnerable in regard to contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Comorbidities are reported to increase the risk for more severe COVID-19 outcomes, often requiring hospitalization. However, the evidence on disease severity and comorbidities among South African HCWs is lacking. This retrospective study analyzed the prevalence of comorbidities among HCW hospital…
Sars-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa
The analysis of SARS-CoV-2 cases in sentinel LTCFs in South Africa points to an encouraging trend of decreasing numbers of outbreaks, cases and risk for mortality since the first wave. LTCFs are likely to have learnt from international experience and adopted national protocols, which include improved measures to limit transmission and administer early and appropriate clinical care
The association of Sars-CoV-2 infection and tuberculosis disease with unfavorable treatment outcomes
Background Whether SARS-CoV-2 infection and its management influence tuberculosis (TB) treatment outcomes is uncertain. We synthesized evidence on the association of SARS-CoV-2 coinfection ( Coinfection Review ) and its management ( Clinical Management Review ) on treatment outcomes among people with tuberculosis (TB) disease. Methods We systematically searched the literature from 1 January 2020 to 6 February 2022. Primary outcomes included: unfa…
Differential in-hospital mortality and intensive care treatment over time
There are limited published data within sub-Saharan Africa describing hospital pathways of COVID-19 patients hospitalized. These data are crucial for the parameterisation of epidemiological and cost models, and for planning purposes for the region. We evaluated COVID-19 hospital admissions from the South African national hospital surveillance system (DATCOV) during the first three COVID-19 waves between May 2020 and August 2021. We describe proba…
Using generalized structured additive regression models to determine factors associated with and clusters for Covid-19 hospital deaths in South Africa
The results show substantial COVID-19 in-hospital mortality variation across the 52 districts. Our analysis provides information that can be important for strengthening health policies and the public health system for the benefit of the whole South African population. Understanding differences in in-hospital COVID-19 mortality across space could guide interventions to achieve better health outcomes in affected districts
Long Covid
INTRODUCTION: A proportion of people develop Long Covid after acute COVID-19, but with most studies concentrated in high-income countries (HICs), the global burden is largely unknown. Our study aims to characterise long-term COVID-19 sequelae in populations globally and compare the prevalence of reported symptoms in HICs and low-income and middle-income countries (LMICs). METHODS: A prospective, observational study in 17 countries in Africa, Asia…
Safety, effectiveness and immunogenicity of heterologous mRNA-1273 boost after prime with Ad26.COV2.S among healthcare workers in South Africa
Limited studies have been conducted on the safety and effectiveness of heterologous COVID-19 vaccine boosting in lower income settings, especially those with high-HIV prevalence., The Sisonke Heterologous mRNA-1273 boost after prime with Ad26.COV2.S (SHERPA) trial evaluated a mRNA-1273 boost after Ad26.COV2.S priming in South Africa. SHERPA was a single-arm, open-label, phase 3 study nested in the Sisonke implementation trial of 500000 healthcare…
Actor sensemaking and its role in implementation of the decentralized drug-resistant tuberculosis policy in South Africa
South Africa has a high burden of drug-resistant tuberculosis (DR-TB). A policy to decentralize DR-TB treatment from specialized central hospitals to more accessible district facilities was introduced in 2011, but to date implementation has been suboptimal, with variable pace, coverage, and models of care emerging. This study explored multilevel policy implementation of DR-TB decentralization in two provinces of South Africa, Western Cape and Kwa…
Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa
Several tuberculosis (TB) vaccines intended for adults and adolescents are in late-stage clinical trials, but there is limited research into how a new TB vaccine would be introduced. South Africa is at the forefront of TB vaccine research, with involvement in the clinical trials of leading candidates. We sought to understand what the priorities and implementation approach of a potential new TB vaccine in South Africa would be. We conducted semi-s…
Medicine (10 obras) · Political science (6 obras) · Economic growth (5 obras) · Global Maternal and Child Health (5 obras) · Internal Medicine (5 obras) · Public health (5 obras) · Business (4 obras) · Economics (4 obras) · Environmental health (4 obras) · Health care (4 obras)