Frank van Leth
Dados Biográficos
| ID | 6162747 |
|---|---|
| NOME | Frank van Leth |
| PRENOMES | Frank |
| SOBRENOME | van Leth |
| ASSINATURA | VAN LETH F |
| AFILIAÇÕES | Amsterdam Institute for Global Health and Development |
| ORCID | 0000-0002-5490-8968 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 8 |
| TOTAL DE CITAÇÕES | 1 |
| TOTAL COMO AUTOR | 8 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2008 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 1 |
Syndemic processes between non-communicable diseases and HIV within the Kingdom of Eswatini
BACKGROUND: Sub-Saharan Africa faces a double burden of disease due to the continued high prevalence of infectious diseases such as HIV and tuberculosis, and a concurrent increase in non-communicable diseases. The co-occurrence and clustering of multiple diseases can cause a syndemic, synergistically interacting epidemics, driven by context. METHODS: This cross-sectional study investigated potential syndemics in Eswatini, by determining geospatia…
Reasons for, and factors associated with, positive HIV retesting
Eswatini has a high HIV prevalence but has made progress towards improving HIV-status awareness, ART uptake and viral suppression. However, there is still a delay in ART initiation, which could partly be attributed to positive HIV-retesting. This study examines reasons for, and factors associated with, positive HIV-retesting among MaxART participants in Eswatini. Data from 601 participants is included in this cross-sectional study. Descriptive st…
Neighbourhood risk factors of recurrent tuberculosis in Cape Town
BACKGROUND: Individuals with a history of tuberculosis (TB) disease are at higher risk of developing a subsequent episode than those without. Considering the role of social and environmental factors in tuberculosis, we assessed neighbourhood-level risk factors associated with recurrent tuberculosis in Cape Town, South Africa. METHODS: This cohort consisted of patients who completed treatment for their first drug-sensitive TB episode between 2003 …
Intention of physicians to implement guidelines for screening and treatment of latent tuberculosis infection in HIV-infected patients in The Netherlands
Intended implementation of the national HIV-TB guidelines in the Netherlands is poor, due to a disconnect between clinical practice and evidence-based recommendations in the guideline. There is an urgent need to reconcile the views of HIV-physicians, public health experts, and guideline committee members, regarding the best strategy to address HIV-TB co-infection in the Netherlands
TB-HIV co-infection in the Netherlands
BACKGROUND: Knowledge of the HIV status in patients with tuberculosis (TB) and vice versa is crucial for proper individual patient management, while knowledge of the prevalence of co-infection guides preventive and therapeutic strategies. The aim of the study was to assess if national disease databases on TB and HIV are adequate sources to provide this information. METHODS: A two way capture-recapture analysis to assess the completeness of the re…
Implementation and effect of intensified case finding on diagnosis of tuberculosis in a large urban HIV clinic in Uganda
Implementation of ICF in a large HIV clinic yielded more TB suspects and cases, but substantially increased costs and was unable to capture the majority of TB suspects who were referred for diagnosis by clinicians through PCF. The overall yield of TB cases in a mature HIV clinic was low, although targeted screening of those recently enrolled in care may increase the yield
The effect of tuberculosis and antiretroviral treatment on CD4+ cell count response in HIV-positive tuberculosis patients in Mozambique
In this study, no independent effect of TB treatment on CD4+ cell count was found. HIV-infected TB patients on ART had a significantly higher CD4+ cell count than those not receiving ART. CD4+ cell counts for patients not on ART at TB treatment start, remained below the cut off for initiating ART during the first three months of TB treatment; therefore some delay in getting the first CD4+ cell count would not lead to missing the opportunity to st…
Implementation of a national anti-tuberculosis drug resistance survey in Tanzania
Careful preparation of the survey, timing of planned activities, a strong emphasis on data capture tools and data management, and timely supervision are essential for a proper implementation of a national drug resistance survey
TB-HIV co-infection in the Netherlands
BACKGROUND: Knowledge of the HIV status in patients with tuberculosis (TB) and vice versa is crucial for proper individual patient management, while knowledge of the prevalence of co-infection guides preventive and therapeutic strategies. The aim of the study was to assess if national disease databases on TB and HIV are adequate sources to provide this information. METHODS: A two way capture-recapture analysis to assess the completeness of the re…
Implementation of a national anti-tuberculosis drug resistance survey in Tanzania
Careful preparation of the survey, timing of planned activities, a strong emphasis on data capture tools and data management, and timely supervision are essential for a proper implementation of a national drug resistance survey
Implementation and effect of intensified case finding on diagnosis of tuberculosis in a large urban HIV clinic in Uganda
Implementation of ICF in a large HIV clinic yielded more TB suspects and cases, but substantially increased costs and was unable to capture the majority of TB suspects who were referred for diagnosis by clinicians through PCF. The overall yield of TB cases in a mature HIV clinic was low, although targeted screening of those recently enrolled in care may increase the yield
The effect of tuberculosis and antiretroviral treatment on CD4+ cell count response in HIV-positive tuberculosis patients in Mozambique
In this study, no independent effect of TB treatment on CD4+ cell count was found. HIV-infected TB patients on ART had a significantly higher CD4+ cell count than those not receiving ART. CD4+ cell counts for patients not on ART at TB treatment start, remained below the cut off for initiating ART during the first three months of TB treatment; therefore some delay in getting the first CD4+ cell count would not lead to missing the opportunity to st…
Intention of physicians to implement guidelines for screening and treatment of latent tuberculosis infection in HIV-infected patients in The Netherlands
Intended implementation of the national HIV-TB guidelines in the Netherlands is poor, due to a disconnect between clinical practice and evidence-based recommendations in the guideline. There is an urgent need to reconcile the views of HIV-physicians, public health experts, and guideline committee members, regarding the best strategy to address HIV-TB co-infection in the Netherlands
TB-HIV co-infection in the Netherlands
BACKGROUND: Knowledge of the HIV status in patients with tuberculosis (TB) and vice versa is crucial for proper individual patient management, while knowledge of the prevalence of co-infection guides preventive and therapeutic strategies. The aim of the study was to assess if national disease databases on TB and HIV are adequate sources to provide this information. METHODS: A two way capture-recapture analysis to assess the completeness of the re…
Reasons for, and factors associated with, positive HIV retesting
Eswatini has a high HIV prevalence but has made progress towards improving HIV-status awareness, ART uptake and viral suppression. However, there is still a delay in ART initiation, which could partly be attributed to positive HIV-retesting. This study examines reasons for, and factors associated with, positive HIV-retesting among MaxART participants in Eswatini. Data from 601 participants is included in this cross-sectional study. Descriptive st…
Neighbourhood risk factors of recurrent tuberculosis in Cape Town
BACKGROUND: Individuals with a history of tuberculosis (TB) disease are at higher risk of developing a subsequent episode than those without. Considering the role of social and environmental factors in tuberculosis, we assessed neighbourhood-level risk factors associated with recurrent tuberculosis in Cape Town, South Africa. METHODS: This cohort consisted of patients who completed treatment for their first drug-sensitive TB episode between 2003 …
Syndemic processes between non-communicable diseases and HIV within the Kingdom of Eswatini
BACKGROUND: Sub-Saharan Africa faces a double burden of disease due to the continued high prevalence of infectious diseases such as HIV and tuberculosis, and a concurrent increase in non-communicable diseases. The co-occurrence and clustering of multiple diseases can cause a syndemic, synergistically interacting epidemics, driven by context. METHODS: This cross-sectional study investigated potential syndemics in Eswatini, by determining geospatia…
Medicine (8 obras) · Pathology (6 obras) · Tuberculosis (6 obras) · Internal Medicine (5 obras) · Tuberculosis Research and Epidemiology (5 obras) · Biostatistics (4 obras) · Environmental health (4 obras) · Family medicine (4 obras) · Demography (3 obras) · Epidemiology (3 obras)