DA Lawlor
Biographic Data
| ID | 6166532 |
|---|---|
| NAME | DA Lawlor |
| FAMILY NAME | DA Lawlor |
| SIGNATURE | DA LAWLOR |
| AFFILIATIONS | University of Bristol |
| VERIFIED | No |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 6 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2011 |
| LATEST PUBLICATION YEAR | 2012 |
| H-INDEX | 0 |
OP62 The Influence of Prenatal Maternal and Paternal Anxiety and Depression on Cardiovascular Biomarkers in the Child at age 10
Background The aim of the current study was to investigate whether exposure to prenatal maternal anxiety and depression influenced later offspring glucose, lipid and inflammatory markers via intrauterine mechanisms. Methods Data from a prospective birth cohort based in the South West of England were used. Our analysis included 2839 mother-children duos and 2361 father-child duos for outcomes assessed at mean age 9.9 years (non-fasting cholesterol…
OP25 Using Linear Spline Multilevel Models to Assess Socioeconomic Differences in Trajectories of Diet, Physical Activity and Fat Mass Across Childhood
Background Lower socioeconomic position (SEP) is a risk factor for obesity in children and adolescents in high-income countries. Since diet and physical activity are the main drivers of obesity, the socioeconomic differential in obesity is likely to arise through SEP differences in one or both of these. Methods We explored SEP differences in trajectories of fat mass, energy intake and physical activity (PA) across childhood and early adolescence,…
OP11 The Association of Childhood Adiposity, and its Distribution, with Cardiometabolic Outcomes
Background Adiposity in childhood has been associated with increased cardiovascular risk which may be established in childhood and adolescence. Also centrally distributed fat (waist circumference) has been suggested to be a better marker of cardiometabolic risk compared to body mass index (BMI). We aimed to assess the association of adiposity measures with cardiometabolic outcomes in children and consider if the magnitude of these associations di…
OP61 Is Maternal Iron Status Associated with offspring’s Blood Pressure and Adiposity? A Mendelian Randomization Study
Background Iron deficiency during pregnancy is a common problem. Experimental animal studies suggest that mothers deficient in iron during pregnancy are more likely to have offspring who become obese and have higher blood pressure. The use of random assortment of genes from parents to offspring can provide a method for assessing the causal impact of nutritional exposures, which is less likely to be influenced by confounding and reverse causality.…
Birth size differences between white British and Pakistani origin infants by generation
Background There is a growing recognition that being born small is associated with risk of adult diseases such as Type 2 diabetes and cardiovascular disease, in addition to its known adverse effects on perinatal and infant outcomes. Previous studies have shown markedly lower birthweight among infants of South Asian origin compared to those of white British origin and there is a suggestion that such differences may mask greater central adiposity i…
Associations of mortality rates with height using son's height as an instrumental variable
Objectives Height has been negatively associated with mortality from circulatory disease, but positively associated with mortality from most forms of cancer. These results are vulnerable to confounding, including the confounding effect of early stages of disease causing shrinkage and later death. To avoid these problems, we used the height of subjects' sons as an instrument for subjects' own height. Design A record linkage cohort study of over 2 …
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Birth size differences between white British and Pakistani origin infants by generation
Background There is a growing recognition that being born small is associated with risk of adult diseases such as Type 2 diabetes and cardiovascular disease, in addition to its known adverse effects on perinatal and infant outcomes. Previous studies have shown markedly lower birthweight among infants of South Asian origin compared to those of white British origin and there is a suggestion that such differences may mask greater central adiposity i…
Associations of mortality rates with height using son's height as an instrumental variable
Objectives Height has been negatively associated with mortality from circulatory disease, but positively associated with mortality from most forms of cancer. These results are vulnerable to confounding, including the confounding effect of early stages of disease causing shrinkage and later death. To avoid these problems, we used the height of subjects' sons as an instrument for subjects' own height. Design A record linkage cohort study of over 2 …
OP62 The Influence of Prenatal Maternal and Paternal Anxiety and Depression on Cardiovascular Biomarkers in the Child at age 10
Background The aim of the current study was to investigate whether exposure to prenatal maternal anxiety and depression influenced later offspring glucose, lipid and inflammatory markers via intrauterine mechanisms. Methods Data from a prospective birth cohort based in the South West of England were used. Our analysis included 2839 mother-children duos and 2361 father-child duos for outcomes assessed at mean age 9.9 years (non-fasting cholesterol…
OP25 Using Linear Spline Multilevel Models to Assess Socioeconomic Differences in Trajectories of Diet, Physical Activity and Fat Mass Across Childhood
Background Lower socioeconomic position (SEP) is a risk factor for obesity in children and adolescents in high-income countries. Since diet and physical activity are the main drivers of obesity, the socioeconomic differential in obesity is likely to arise through SEP differences in one or both of these. Methods We explored SEP differences in trajectories of fat mass, energy intake and physical activity (PA) across childhood and early adolescence,…
OP11 The Association of Childhood Adiposity, and its Distribution, with Cardiometabolic Outcomes
Background Adiposity in childhood has been associated with increased cardiovascular risk which may be established in childhood and adolescence. Also centrally distributed fat (waist circumference) has been suggested to be a better marker of cardiometabolic risk compared to body mass index (BMI). We aimed to assess the association of adiposity measures with cardiometabolic outcomes in children and consider if the magnitude of these associations di…
OP61 Is Maternal Iron Status Associated with offspring’s Blood Pressure and Adiposity? A Mendelian Randomization Study
Background Iron deficiency during pregnancy is a common problem. Experimental animal studies suggest that mothers deficient in iron during pregnancy are more likely to have offspring who become obese and have higher blood pressure. The use of random assortment of genes from parents to offspring can provide a method for assessing the causal impact of nutritional exposures, which is less likely to be influenced by confounding and reverse causality.…
Medicine (6 works) · Demography (5 works) · Internal Medicine (5 works) · Internal Medicine (5 works) · Body mass index (3 works) · Cohort study (3 works) · Confounding (3 works) · Environmental health (3 works) · Health, Environment, Cognitive Aging (3 works) · Obesity, Physical Activity, Diet (3 works)