Bruno Giordani
Biographic Data
| ID | 6206360 |
|---|---|
| NAME | Bruno Giordani |
| GIVEN NAMES | Bruno |
| FAMILY NAME | Giordani |
| SIGNATURE | GIORDANI B |
| AFFILIATIONS | University of Michigan |
| ORCID | 0000-0001-5921-3455 |
| VERIFIED | Yes |
| TOTAL WORKS | 16 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 16 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1982 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Assessing Cognitive Impairment in the Health and Retirement Study Harmonized Cognitive Assessment Protocol Project: Comparing a Diagnostic Algorithm With a Diagnostic Consensus Panel
BackgroundAccurate classification of cognitive impairment in population studies is challenging.ObjectiveTo compare the performance of a diagnostic algorithm with a clinical consensus panel.SampleIn 2016, the Health and Retirement Study (HRS) implemented the Harmonized Cognitive Assessment Protocol Project (HRS-HCAP) to streamline cognitive assessments for select HRS participants.MethodsThe Manly-Jones HCAP diagnostic classification was used to cl…
Association of adult caregiver depression with developmental disorder likelihood in Ugandan children perinatally exposed and unexposed to HIV
We assessed whether higher caregiver depression is associated with increased likelihood of caregivers rating their children as screening positive for developmental disorders—autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder, emotional behavioral disorder, and functional impairment (FI)—among Ugandan children perinatally exposed and unexposed to HIV. Children and their primary caregivers were followed for 12 months. Caregive…
Impact of a Multi-Component Physical Activity Intervention on Psychological Well-Being in Older Adults: A Pilot Study
While the positive effects of physical activity (PA) on mental health are well documented, limited research has explored its influence on the positive psychological well-being in elderly individuals. This study examined the effects of a multi-component PA intervention on various facets of psychological well-being among older adults residing in retirement homes. Fifty-eight elderly individuals (mean age = 83.8 years, 76.3% female) residing in reti…
Developmental Disorder Probability Scores at 6–18 Years Old in Relation to In-Utero/Peripartum Antiretroviral Drug Exposure among Ugandan Children
(1) We examined the hypothesis that in utero/peripartum antiretroviral (IPA) exposure may affect the likelihood of developmental disorders-i.e., attention deficit and hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and functional impairment (FI). (2) Children and their primary caregivers were enrolled and followed for 12 months. The sample included 250 children perinatally HIV-infected (CPHIV), 250 children HIV-exposed and uninfect…
Toxic Psychosocial Stress, Resiliency Resources and Time to Dementia Diagnosis in a Nationally Representative Sample of Older Americans in the Health and Retirement Study from 2006–2016
TS is a contextual driver of incident dementia that seemingly operates in a race and RPF-dependent fashion among American adults. Association pattern suggests that TS may overwhelm the cognitive reserve benefit of RPF particularly in status-inconsistent contexts including persons subjected to discrimination despite high education and persons of African American descent despite high mastery. Policies that reduce discrimination and promote equitabl…
Technology-Enhanced 4Active Intervention Impacting Psychological Well-Being and Physical Activity among Older Adults: A Pilot Study
It is concluded that engaging in the two-level 4Active intervention including group-based multicomponent exercises and technology-enhanced self-exercises is more effective in decreasing negative affect and increasing weekly moderate PA METS-min in physically and cognitively frail older adults over time, compared with attending the group exercises alone
Association of serum Pufa and linear growth over 12 months among 6–10 years old Ugandan children with or without HIV
Objective: To quantify PUFA-associated improvement in linear growth among children aged 6–10 years. Design: Serum fatty acids (FA), including essential FA (EFA) (linoleic acid (LA) and α -linolenic acid (ALA)) were quantified at baseline using GC-MS technology. FA totals by class ( n -3, n-6, n -9, PUFA and SFA) and FA ratios were calculated. Height-for-age Z -score (HAZ) relative to WHO population reference values were calculated longitudinally …
The Relationship of Race, Psychosocial Stress and Resiliency Indicators to Neurocognitive Impairment among Older Americans Enrolled in the Health and Retirement Survey: A Cross-Sectional Study
Discrimination, chronic stress, and low mastery were associated with worse cognition. Persisting cognitive disadvantage for AA vs. White/Other race only among high mastery adults suggests that adverse social experiences may counteract mastery-associated cognitive benefits among AA population. TS reduction through policies that promote equal treatment by race/ethnicity in social life, health, justice, and economic systems may promote successful co…
Toxic Stress and Quality of Life in Early School‐Aged Ugandan Children With and Without Perinatal Human Immunodeficiency Virus Infection
Caregiver's and child's self-reported quality of life (QOL) was defined using standardized questionnaires in a sample (N = 277) of 6-10 years old HIV-infected, HIV-exposed uninfected, and HIV-unexposed uninfected children from Uganda. Psychosocial stress (acute stress and cumulative lifetime adversity) and physiologic stress (dysregulations across 13 biomarkers), perinatal HIV status, and their interaction were related to child QOL via general li…
Psychosocial Adjustment in Ugandan Children: Coping With Human Immunodeficiency Virus Exposure, Lifetime Adversity, and Importance of Social Support
Cumulative lifetime adversity and social support were investigated as determinants of psychosocial adjustment (esteem, distress, hopefulness, positive outlook/future aspirations, and sense of purpose) over 12 months in 6-10-years-old HIV-infected, HIV-exposed uninfected and HIV-unexposed uninfected children from Uganda. Each determinant and psychosocial adjustment indicator was self-reported using standardized questionnaires administered at basel…
Immunological correlates of behavioral problems in school-aged children living with HIV in Kayunga, Uganda
Poorer behavioral outcomes were associated with higher viral loads while higher CD8 activation was associated with poorer emotional and behavioral outcomes. Complete immunological assessments for children living with HIV could include commonly used viral and immunological parameters to identify those at higher risk of having negative behavior outcomes and who would benefit the most from behavioral interventions
Designing and evaluating Brain Powered Games for cognitive training and rehabilitation in at-risk African children
Results provide preliminary support for the acceptability, feasibility, and neurocognitive benefit of BPG and its utility as a model platform for computerized cognitive training in cross-cultural low-resource settings
Using Pictures to Evoke Spiritual feelings in Breast Cancer Patients: Development of a New Paradigm for Neuroimaging Studies
Elevated Cortisol Levels in Cushing’s Disease Are Associated With Cognitive Decrements
OBJECTIVE: The objective of this study was to use Cushing's disease as a unique human model to elucidate the cognitive deficits resulting from exposure to chronic stress-level elevations of endogenous cortisol. METHODS: Forty-eight patients with a first episode of acute, untreated Cushing's disease and 38 healthy control subjects were studied. RESULTS: Scores for four of five verbal IQ subtests were significantly lower in patients with Cushing's …
Neuropsychological Predictors of Complex Obstacle Avoidance in Healthy Older Adults
Global cognitive impairment in older adults has been associated with a greater risk of falling, and tripping has been implicated as an important factor in a large percentage of these falls. In order to evaluate the role of specific cognitive domains in tripping and falling, 23 healthy older adults completed basic and complex obstacle avoidance tasks, as well as a battery of neuropsychological tests. Using multiple regression analysis, a select pa…
Coronary-Prone Behavior Pattern and Cardiovascular Response in Persons with and without Coronary Heart Disease
The purpose of this investigation was to examine the psychophysiologic responses of Type A and Type B individuals, among persons with and without coronary heart disease (CHD). Subjects were 58 adult male volunteers; 24 had a history of myocardial infarction or clinically diagnosed angina pectoris (CHD) and 34 had been designated free of coronary disease following recent cardiologic examination (non-CHD). All subjects had normotensive resting bloo…
Neuropsychological Predictors of Complex Obstacle Avoidance in Healthy Older Adults
Global cognitive impairment in older adults has been associated with a greater risk of falling, and tripping has been implicated as an important factor in a large percentage of these falls. In order to evaluate the role of specific cognitive domains in tripping and falling, 23 healthy older adults completed basic and complex obstacle avoidance tasks, as well as a battery of neuropsychological tests. Using multiple regression analysis, a select pa…
Coronary-Prone Behavior Pattern and Cardiovascular Response in Persons with and without Coronary Heart Disease
The purpose of this investigation was to examine the psychophysiologic responses of Type A and Type B individuals, among persons with and without coronary heart disease (CHD). Subjects were 58 adult male volunteers; 24 had a history of myocardial infarction or clinically diagnosed angina pectoris (CHD) and 34 had been designated free of coronary disease following recent cardiologic examination (non-CHD). All subjects had normotensive resting bloo…
Neuropsychological Predictors of Complex Obstacle Avoidance in Healthy Older Adults
Global cognitive impairment in older adults has been associated with a greater risk of falling, and tripping has been implicated as an important factor in a large percentage of these falls. In order to evaluate the role of specific cognitive domains in tripping and falling, 23 healthy older adults completed basic and complex obstacle avoidance tasks, as well as a battery of neuropsychological tests. Using multiple regression analysis, a select pa…
Elevated Cortisol Levels in Cushing’s Disease Are Associated With Cognitive Decrements
OBJECTIVE: The objective of this study was to use Cushing's disease as a unique human model to elucidate the cognitive deficits resulting from exposure to chronic stress-level elevations of endogenous cortisol. METHODS: Forty-eight patients with a first episode of acute, untreated Cushing's disease and 38 healthy control subjects were studied. RESULTS: Scores for four of five verbal IQ subtests were significantly lower in patients with Cushing's …
Using Pictures to Evoke Spiritual feelings in Breast Cancer Patients: Development of a New Paradigm for Neuroimaging Studies
Immunological correlates of behavioral problems in school-aged children living with HIV in Kayunga, Uganda
Poorer behavioral outcomes were associated with higher viral loads while higher CD8 activation was associated with poorer emotional and behavioral outcomes. Complete immunological assessments for children living with HIV could include commonly used viral and immunological parameters to identify those at higher risk of having negative behavior outcomes and who would benefit the most from behavioral interventions
Designing and evaluating Brain Powered Games for cognitive training and rehabilitation in at-risk African children
Results provide preliminary support for the acceptability, feasibility, and neurocognitive benefit of BPG and its utility as a model platform for computerized cognitive training in cross-cultural low-resource settings
Toxic Stress and Quality of Life in Early School‐Aged Ugandan Children With and Without Perinatal Human Immunodeficiency Virus Infection
Caregiver's and child's self-reported quality of life (QOL) was defined using standardized questionnaires in a sample (N = 277) of 6-10 years old HIV-infected, HIV-exposed uninfected, and HIV-unexposed uninfected children from Uganda. Psychosocial stress (acute stress and cumulative lifetime adversity) and physiologic stress (dysregulations across 13 biomarkers), perinatal HIV status, and their interaction were related to child QOL via general li…
Psychosocial Adjustment in Ugandan Children: Coping With Human Immunodeficiency Virus Exposure, Lifetime Adversity, and Importance of Social Support
Cumulative lifetime adversity and social support were investigated as determinants of psychosocial adjustment (esteem, distress, hopefulness, positive outlook/future aspirations, and sense of purpose) over 12 months in 6-10-years-old HIV-infected, HIV-exposed uninfected and HIV-unexposed uninfected children from Uganda. Each determinant and psychosocial adjustment indicator was self-reported using standardized questionnaires administered at basel…
The Relationship of Race, Psychosocial Stress and Resiliency Indicators to Neurocognitive Impairment among Older Americans Enrolled in the Health and Retirement Survey: A Cross-Sectional Study
Discrimination, chronic stress, and low mastery were associated with worse cognition. Persisting cognitive disadvantage for AA vs. White/Other race only among high mastery adults suggests that adverse social experiences may counteract mastery-associated cognitive benefits among AA population. TS reduction through policies that promote equal treatment by race/ethnicity in social life, health, justice, and economic systems may promote successful co…
Developmental Disorder Probability Scores at 6–18 Years Old in Relation to In-Utero/Peripartum Antiretroviral Drug Exposure among Ugandan Children
(1) We examined the hypothesis that in utero/peripartum antiretroviral (IPA) exposure may affect the likelihood of developmental disorders-i.e., attention deficit and hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and functional impairment (FI). (2) Children and their primary caregivers were enrolled and followed for 12 months. The sample included 250 children perinatally HIV-infected (CPHIV), 250 children HIV-exposed and uninfect…
Toxic Psychosocial Stress, Resiliency Resources and Time to Dementia Diagnosis in a Nationally Representative Sample of Older Americans in the Health and Retirement Study from 2006–2016
TS is a contextual driver of incident dementia that seemingly operates in a race and RPF-dependent fashion among American adults. Association pattern suggests that TS may overwhelm the cognitive reserve benefit of RPF particularly in status-inconsistent contexts including persons subjected to discrimination despite high education and persons of African American descent despite high mastery. Policies that reduce discrimination and promote equitabl…
Technology-Enhanced 4Active Intervention Impacting Psychological Well-Being and Physical Activity among Older Adults: A Pilot Study
It is concluded that engaging in the two-level 4Active intervention including group-based multicomponent exercises and technology-enhanced self-exercises is more effective in decreasing negative affect and increasing weekly moderate PA METS-min in physically and cognitively frail older adults over time, compared with attending the group exercises alone
Association of serum Pufa and linear growth over 12 months among 6–10 years old Ugandan children with or without HIV
Objective: To quantify PUFA-associated improvement in linear growth among children aged 6–10 years. Design: Serum fatty acids (FA), including essential FA (EFA) (linoleic acid (LA) and α -linolenic acid (ALA)) were quantified at baseline using GC-MS technology. FA totals by class ( n -3, n-6, n -9, PUFA and SFA) and FA ratios were calculated. Height-for-age Z -score (HAZ) relative to WHO population reference values were calculated longitudinally …
Impact of a Multi-Component Physical Activity Intervention on Psychological Well-Being in Older Adults: A Pilot Study
While the positive effects of physical activity (PA) on mental health are well documented, limited research has explored its influence on the positive psychological well-being in elderly individuals. This study examined the effects of a multi-component PA intervention on various facets of psychological well-being among older adults residing in retirement homes. Fifty-eight elderly individuals (mean age = 83.8 years, 76.3% female) residing in reti…
Assessing Cognitive Impairment in the Health and Retirement Study Harmonized Cognitive Assessment Protocol Project: Comparing a Diagnostic Algorithm With a Diagnostic Consensus Panel
BackgroundAccurate classification of cognitive impairment in population studies is challenging.ObjectiveTo compare the performance of a diagnostic algorithm with a clinical consensus panel.SampleIn 2016, the Health and Retirement Study (HRS) implemented the Harmonized Cognitive Assessment Protocol Project (HRS-HCAP) to streamline cognitive assessments for select HRS participants.MethodsThe Manly-Jones HCAP diagnostic classification was used to cl…
Association of adult caregiver depression with developmental disorder likelihood in Ugandan children perinatally exposed and unexposed to HIV
We assessed whether higher caregiver depression is associated with increased likelihood of caregivers rating their children as screening positive for developmental disorders—autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder, emotional behavioral disorder, and functional impairment (FI)—among Ugandan children perinatally exposed and unexposed to HIV. Children and their primary caregivers were followed for 12 months. Caregive…
Medicine (13 works) · Psychiatry (12 works) · Psychology (9 works) · Clinical Psychology (8 works) · Internal Medicine (8 works) · Clinical Psychology (6 works) · Psychosocial (5 works) · Cognition (4 works) · Confidence interval (4 works) · Gerontology (4 works)