Philippe J Guérin
Datos Biográficos
| ID | 6398166 |
|---|---|
| NOMBRE | Philippe J Guérin |
| NOMBRES | Philippe J |
| APELLIDO | Guérin |
| FIRMA | GUÉRIN P J |
| AFILIACIONES | University of Oxford |
| ORCID | 0000-0002-6008-2963 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 13 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 13 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2014 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Model-guided geospatial surveillance system for antimalarial drug resistance
Disease surveillance activities are usually resource-constrained and should be optimised to generate the most informative scientific findings, and to make the best use of time, finances, and personnel. India has a high population density, diverse geography and climatic conditions, and difficult terrain. With respect to malaria, Plasmodium falciparum and Plasmodium vivax are endemic, with substantial variability of transmission across the country.…
Unveiling sub-populations in critical care settings
Background: Disease presentation and progression can vary greatly in heterogeneous diseases, such as COVID-19, with variability in patient outcomes, even within the hospital setting. This variability underscores the need for tailored treatment approaches based on distinct clinical subgroups. Objectives: This study aimed to identify COVID-19 patient subgroups with unique clinical characteristics using real-world data (RWD) from electronic health r…
Systematic scoping review of the noma evidence landscape
BACKGROUND: Noma (cancrum oris) is a severe gangrenous disease of the mouth and oro-facial structures. Noma often affects young children living in extreme poverty, malnutrition and poor sanitation. Gaps remain in understanding its aetiology, pathogenesis, prevention and treatment. METHODS AND FINDINGS: We systematically searched databases for all primary research studies (clinical trials, cohort studies, case-control, cross-sectional, other obser…
Wrangling Real-World Data
Data-driven approaches to clinical research are necessary for understanding and effectively treating infectious diseases. However, challenges such as issues with data validity, lack of collaboration, and difficult-to-treat infectious diseases (e.g., those that are rare or newly emerging) hinder research. Prioritizing innovative methods to facilitate the continued use of data generated during routine clinical care for research, but in an organized…
Comparison of WHO versus national Covid-19 therapeutic guidelines across the world
BACKGROUND: The COVID-19 pandemic affected all WHO member states. We compared and contrasted the COVID-19 treatment guidelines of each member state with the WHO COVID-19 therapeutic guidelines. METHODS: Ministries of Health or accessed National Infectious Disease websites and other relevant bodies and experts were contacted to obtain national guidelines (NGs) for COVID-19 treatment. NGs were included only if they delineated specific pharmacologic…
Une écriture de la dissimulation. Aperçus sur les lectures ésotériques françaises de la Comédie (et du Convivio)
Qu’est-ce qui dans la Comédie ‘autorise’ son interprétation en termes ésotériques ? Pourquoi une telle veine herméneutique, tendanciellement ‘complotiste’, est-elle particulièrement florissante en France ? La première de ces questions conduit à s’interroger sur la question de l’allégorie chez Dante (en partant du Convivio où elle se pose explicitement pour la première fois, et de sa réverbération sur la compréhension des Rime allégoriques). La ré…
Safety and efficacy of primaquine in patients with Plasmodium vivax malaria from South Asia
Un projet pour le Dante français (ou en France) et le « siècle sans Dante »
Characterisation of populations at risk of sub-optimal dosing of artemisinin-based combination therapy in Africa
Selection of resistant malaria strains occurs when parasites are exposed to inadequate antimalarial drug concentrations. The proportion of uncomplicated falciparum malaria patients at risk of being sub-optimally dosed with the current World Health Organization (WHO) recommended artemisinin-based combination therapies (ACTs) is unknown. This study aims to estimate this proportion and the excess number of treatment failures (recrudescences) associa…
Definitions matter
Therapeutic efficacy in COVID-19 is dependent upon disease severity (treatment effect heterogeneity). Unfortunately, definitions of severity vary widely. This compromises the meta-analysis of randomised controlled trials (RCTs) and the therapeutic guidelines derived from them. The World Health Organisation ‘living’ guidelines for the treatment of COVID-19 are based on a network meta-analysis (NMA) of published RCTs. We reviewed the 81 studies inc…
Sabrina Ferrara, La parola dell’esilio. Autore e lettori nelle opere di Dante in esilio, Firenze, Cesati, 2016, 364 p
Une double décision préside sur le plan épistémologique à la conception de cet ambitieux et important travail – par la taille comme par les résultats. Il y a d’abord l’hypothèse de départ, déjà mise à l’épreuve par l’auteur dans sa thèse de doctorat, ancrée dans le parcours biographique de Dante, selon laquelle la condamnation de 1302 au bannissement de Florence constituerait une ligne de partage absolue, ayant amené Dante à repenser radicalement…
Understanding the mechanisms and drivers of antimicrobial resistance
Pétrarque, ou de l’écriture comme odyssée
La contribution examine la figure d’Ulysse chez Pétrarque, vue comme possible métaphore de l’écriture. D’une écriture qui, se confondant avec la vie et son mouvement même (dont Ulysse est le héros emblématique), est voyage toujours recommencé, à la fois expérience existentielle sans autre terme que la mort et la quête de savoir (y compris comme connaissance de soi) sans fin assignable. Ce sont les modalités de cette errance ulysséenne, de ses flu…
Sin obras prominentes en esta página.
Pétrarque, ou de l’écriture comme odyssée
La contribution examine la figure d’Ulysse chez Pétrarque, vue comme possible métaphore de l’écriture. D’une écriture qui, se confondant avec la vie et son mouvement même (dont Ulysse est le héros emblématique), est voyage toujours recommencé, à la fois expérience existentielle sans autre terme que la mort et la quête de savoir (y compris comme connaissance de soi) sans fin assignable. Ce sont les modalités de cette errance ulysséenne, de ses flu…
Understanding the mechanisms and drivers of antimicrobial resistance
Sabrina Ferrara, La parola dell’esilio. Autore e lettori nelle opere di Dante in esilio, Firenze, Cesati, 2016, 364 p
Une double décision préside sur le plan épistémologique à la conception de cet ambitieux et important travail – par la taille comme par les résultats. Il y a d’abord l’hypothèse de départ, déjà mise à l’épreuve par l’auteur dans sa thèse de doctorat, ancrée dans le parcours biographique de Dante, selon laquelle la condamnation de 1302 au bannissement de Florence constituerait une ligne de partage absolue, ayant amené Dante à repenser radicalement…
Definitions matter
Therapeutic efficacy in COVID-19 is dependent upon disease severity (treatment effect heterogeneity). Unfortunately, definitions of severity vary widely. This compromises the meta-analysis of randomised controlled trials (RCTs) and the therapeutic guidelines derived from them. The World Health Organisation ‘living’ guidelines for the treatment of COVID-19 are based on a network meta-analysis (NMA) of published RCTs. We reviewed the 81 studies inc…
Safety and efficacy of primaquine in patients with Plasmodium vivax malaria from South Asia
Un projet pour le Dante français (ou en France) et le « siècle sans Dante »
Characterisation of populations at risk of sub-optimal dosing of artemisinin-based combination therapy in Africa
Selection of resistant malaria strains occurs when parasites are exposed to inadequate antimalarial drug concentrations. The proportion of uncomplicated falciparum malaria patients at risk of being sub-optimally dosed with the current World Health Organization (WHO) recommended artemisinin-based combination therapies (ACTs) is unknown. This study aims to estimate this proportion and the excess number of treatment failures (recrudescences) associa…
Comparison of WHO versus national Covid-19 therapeutic guidelines across the world
BACKGROUND: The COVID-19 pandemic affected all WHO member states. We compared and contrasted the COVID-19 treatment guidelines of each member state with the WHO COVID-19 therapeutic guidelines. METHODS: Ministries of Health or accessed National Infectious Disease websites and other relevant bodies and experts were contacted to obtain national guidelines (NGs) for COVID-19 treatment. NGs were included only if they delineated specific pharmacologic…
Une écriture de la dissimulation. Aperçus sur les lectures ésotériques françaises de la Comédie (et du Convivio)
Qu’est-ce qui dans la Comédie ‘autorise’ son interprétation en termes ésotériques ? Pourquoi une telle veine herméneutique, tendanciellement ‘complotiste’, est-elle particulièrement florissante en France ? La première de ces questions conduit à s’interroger sur la question de l’allégorie chez Dante (en partant du Convivio où elle se pose explicitement pour la première fois, et de sa réverbération sur la compréhension des Rime allégoriques). La ré…
Unveiling sub-populations in critical care settings
Background: Disease presentation and progression can vary greatly in heterogeneous diseases, such as COVID-19, with variability in patient outcomes, even within the hospital setting. This variability underscores the need for tailored treatment approaches based on distinct clinical subgroups. Objectives: This study aimed to identify COVID-19 patient subgroups with unique clinical characteristics using real-world data (RWD) from electronic health r…
Systematic scoping review of the noma evidence landscape
BACKGROUND: Noma (cancrum oris) is a severe gangrenous disease of the mouth and oro-facial structures. Noma often affects young children living in extreme poverty, malnutrition and poor sanitation. Gaps remain in understanding its aetiology, pathogenesis, prevention and treatment. METHODS AND FINDINGS: We systematically searched databases for all primary research studies (clinical trials, cohort studies, case-control, cross-sectional, other obser…
Wrangling Real-World Data
Data-driven approaches to clinical research are necessary for understanding and effectively treating infectious diseases. However, challenges such as issues with data validity, lack of collaboration, and difficult-to-treat infectious diseases (e.g., those that are rare or newly emerging) hinder research. Prioritizing innovative methods to facilitate the continued use of data generated during routine clinical care for research, but in an organized…
Model-guided geospatial surveillance system for antimalarial drug resistance
Disease surveillance activities are usually resource-constrained and should be optimised to generate the most informative scientific findings, and to make the best use of time, finances, and personnel. India has a high population density, diverse geography and climatic conditions, and difficult terrain. With respect to malaria, Plasmodium falciparum and Plasmodium vivax are endemic, with substantial variability of transmission across the country.…
Medicine (7 obras) · Disease (4 obras) · Art (3 obras) · Environmental health (3 obras) · Humanities (3 obras) · MEDLINE (3 obras) · Pathology (3 obras) · Computer Science (2 obras) · COVID-19 Clinical Research Studies (2 obras) · COVID-19 diagnosis using AI (2 obras)