Zachary Freyberg
Biographic Data
| ID | 6703068 |
|---|---|
| NAME | Zachary Freyberg |
| GIVEN NAMES | Zachary |
| FAMILY NAME | Freyberg |
| SIGNATURE | FREYBERG Z |
| AFFILIATIONS | University of Pittsburgh |
| ORCID | 0000-0001-6460-0118 |
| VERIFIED | Yes |
| TOTAL WORKS | 3 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 3 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2014 |
| LATEST PUBLICATION YEAR | 2022 |
| H-INDEX | 0 |
Brain region- and sex-specific transcriptional profiles of microglia
Microglia are resident macrophages of the brain, performing roles related to brain homeostasis, including modulation of synapses, trophic support, phagocytosis of apoptotic cells and debris, as well as brain protection and repair. Studies assessing morphological and transcriptional features of microglia found regional differences as well as sex differences in some investigated brain regions. However, markers used to isolate microglia in many prev…
Does the Time of Drug Administration Alter the Metabolic Risk of Aripiprazole
Antipsychotic drugs cause metabolic abnormalities through a mechanism that involves antagonism of D 2 dopamine receptors (D 2 R). Under healthy conditions, insulin release follows a circadian rhythm and is low at night, and in pancreatic beta-cells, D 2 Rs negatively regulate insulin release. Since they are sedating, many antipsychotics are dosed at night. However, the resulting reduction in overnight D 2 R activity may disrupt 24 h rhythms in in…
The write stuff
Clinicians often wonder if the single sentence from the Folstein Mini-Mental Status Exam (MMSE) offers meaningful information about the patient. We compared single sentences derived from the MMSE generated by 3 groups of participants — hospitalized medically-ill patients with psychiatric comorbidity, hospitalized medically-ill patients without psychiatric comorbidity, and non-hospitalized non-psychiatric participants. These sentences were analyze…
No prominent works on this page.
The write stuff
Clinicians often wonder if the single sentence from the Folstein Mini-Mental Status Exam (MMSE) offers meaningful information about the patient. We compared single sentences derived from the MMSE generated by 3 groups of participants — hospitalized medically-ill patients with psychiatric comorbidity, hospitalized medically-ill patients without psychiatric comorbidity, and non-hospitalized non-psychiatric participants. These sentences were analyze…
Does the Time of Drug Administration Alter the Metabolic Risk of Aripiprazole
Antipsychotic drugs cause metabolic abnormalities through a mechanism that involves antagonism of D 2 dopamine receptors (D 2 R). Under healthy conditions, insulin release follows a circadian rhythm and is low at night, and in pancreatic beta-cells, D 2 Rs negatively regulate insulin release. Since they are sedating, many antipsychotics are dosed at night. However, the resulting reduction in overnight D 2 R activity may disrupt 24 h rhythms in in…
Brain region- and sex-specific transcriptional profiles of microglia
Microglia are resident macrophages of the brain, performing roles related to brain homeostasis, including modulation of synapses, trophic support, phagocytosis of apoptotic cells and debris, as well as brain protection and repair. Studies assessing morphological and transcriptional features of microglia found regional differences as well as sex differences in some investigated brain regions. However, markers used to isolate microglia in many prev…
Psychiatry (2 works) · Aripiprazole (1 work) · Biology (1 work) · Cell Biology (1 work) · Central nervous system (1 work) · Circadian rhythm and melatonin (1 work) · Clinical Psychology (1 work) · Clinical Psychology (1 work) · Coding (social sciences (1 work) · Cognition (1 work)