Zhenyu Guo
Biographic Data
| ID | 6714844 |
|---|---|
| NAME | Zhenyu Guo |
| GIVEN NAMES | Zhenyu |
| FAMILY NAME | Guo |
| SIGNATURE | GUO Z |
| AFFILIATIONS | Beijing University of Chinese Medicine |
| ORCID | 0000-0003-2034-4890 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 13 |
| WORKS AS AUTHOR | 10 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1997 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Genetic prediction of micronutrient levels and the risk of multiple system atrophy
Multiple system atrophy (MSA) is a fatal neurodegenerative disorder of elusive pathogenesis, and observational links to micronutrients are prone to confounding. Mendelian randomization (MR) uses genetic variants as instrumental variables to infer causality, minimizing confounding and reverse causation by mimicking randomized controlled trials. We performed a two-sample MR analysis using summary statistics from large-scale genome-wide association …
Xinyin tablets affect mitophagy and cardiomyocyte apoptosis to alleviate chronic heart failure by regulating histone deacetylase 3(HDAC3)-mediated PTEN induced putative kinase 1(Pink1)/Parkin signalin…
Xinyin tablets have potential as an intervention for CHF by improving mitophagy and inhibiting cardiomyocyte apoptosis through the HDAC3-mediated PINK1/Parkin signaling pathway
Chrysotoxine regulates ferroptosis and the PI3K/AKT/mTOR pathway to prevent cervical cancer
Our study indicates that chrysotoxine shows promise as a novel medication for treating CC. The findings provide a scientific foundation for the regulation of cervical cancer by chrysotoxine, presenting new insights into the application of traditional Chinese medicine for fighting CC
The sound of silence
Self-media entrepreneurs from marginalised communities face unique challenges in the rapidly evolving global creative industries. This study examines the lived experiences of Deaf creators on Douyin, China’s leading short-video platform, highlighting how they navigate the socio-technical and economic pressures shaping their labour experiences. Drawing on the ethnographic approach, we uncover the tension between the platform’s promise of visibilit…
Fostering students’ geographical synthetic thinking using geographic subject mind maps
The term “geographical synthetic thinking” is taken from the latest Chinese version of the “Geography Curriculum Standards” (General High School 2017 edition, Compulsory Education 2022 edition) and is one of the four core competencies prioritized in the teaching of geography at the secondary-school level. This study proposes that using geographic subject mind maps improves students’ geographical synthetic thinking and develops a set of geographic…
The whitening effect of cuscutin responsible for traditional use of Bergenia purpurascens
Protective effects of DJ-1 medicated Akt phosphorylation on mitochondrial function are promoted by Da-Bu-Yin-Wan in 1-methyl-4-phenylpyridinium-treated human neuroblastoma SH-SY5Y cells
Da-Bu-Yin-Wan and Qian-Zheng-San, two traditional Chinese herbal formulas, up-regulate the expression of mitochondrial subunit Nadh dehydrogenase 1 synergistically in the mice model of Parkinson's dis…
Dementia is the major cause of functional dependence in the elderly
OBJECTIVES: The purpose of this investigation was to study the role of dementia and other common age-related diseases as determinants of dependence in activities of daily living (ADL) in the elderly. METHODS: The study population consisted of 1745 persons, aged 75 years and older, living in a district of Stockholm. They were examined at baseline and after a 3-year follow-up interval. Katz's index was used to measure functional status. Functional …
Low blood pressure and five-year mortality in a Stockholm cohort of the very old
OBJECTIVES: Low blood pressure has often been reported to be related to excess mortality in people over the age of 75 years. This study examined whether other predictors may account for the association. METHODS: A community-based cohort of 1810 people who were aged 75 years and older was followed for 5 years. RESULTS: The relative risk of death was 1.39 (95% confidence interval [CI] = 1.11, 1.73) for people with systolic pressure lower than 130 m…
Dementia is the major cause of functional dependence in the elderly
OBJECTIVES: The purpose of this investigation was to study the role of dementia and other common age-related diseases as determinants of dependence in activities of daily living (ADL) in the elderly. METHODS: The study population consisted of 1745 persons, aged 75 years and older, living in a district of Stockholm. They were examined at baseline and after a 3-year follow-up interval. Katz's index was used to measure functional status. Functional …
The sound of silence
Self-media entrepreneurs from marginalised communities face unique challenges in the rapidly evolving global creative industries. This study examines the lived experiences of Deaf creators on Douyin, China’s leading short-video platform, highlighting how they navigate the socio-technical and economic pressures shaping their labour experiences. Drawing on the ethnographic approach, we uncover the tension between the platform’s promise of visibilit…
Low blood pressure and five-year mortality in a Stockholm cohort of the very old
OBJECTIVES: Low blood pressure has often been reported to be related to excess mortality in people over the age of 75 years. This study examined whether other predictors may account for the association. METHODS: A community-based cohort of 1810 people who were aged 75 years and older was followed for 5 years. RESULTS: The relative risk of death was 1.39 (95% confidence interval [CI] = 1.11, 1.73) for people with systolic pressure lower than 130 m…
Dementia is the major cause of functional dependence in the elderly
OBJECTIVES: The purpose of this investigation was to study the role of dementia and other common age-related diseases as determinants of dependence in activities of daily living (ADL) in the elderly. METHODS: The study population consisted of 1745 persons, aged 75 years and older, living in a district of Stockholm. They were examined at baseline and after a 3-year follow-up interval. Katz's index was used to measure functional status. Functional …
Da-Bu-Yin-Wan and Qian-Zheng-San, two traditional Chinese herbal formulas, up-regulate the expression of mitochondrial subunit Nadh dehydrogenase 1 synergistically in the mice model of Parkinson's dis…
Protective effects of DJ-1 medicated Akt phosphorylation on mitochondrial function are promoted by Da-Bu-Yin-Wan in 1-methyl-4-phenylpyridinium-treated human neuroblastoma SH-SY5Y cells
Fostering students’ geographical synthetic thinking using geographic subject mind maps
The term “geographical synthetic thinking” is taken from the latest Chinese version of the “Geography Curriculum Standards” (General High School 2017 edition, Compulsory Education 2022 edition) and is one of the four core competencies prioritized in the teaching of geography at the secondary-school level. This study proposes that using geographic subject mind maps improves students’ geographical synthetic thinking and develops a set of geographic…
The whitening effect of cuscutin responsible for traditional use of Bergenia purpurascens
Xinyin tablets affect mitophagy and cardiomyocyte apoptosis to alleviate chronic heart failure by regulating histone deacetylase 3(HDAC3)-mediated PTEN induced putative kinase 1(Pink1)/Parkin signalin…
Xinyin tablets have potential as an intervention for CHF by improving mitophagy and inhibiting cardiomyocyte apoptosis through the HDAC3-mediated PINK1/Parkin signaling pathway
Chrysotoxine regulates ferroptosis and the PI3K/AKT/mTOR pathway to prevent cervical cancer
Our study indicates that chrysotoxine shows promise as a novel medication for treating CC. The findings provide a scientific foundation for the regulation of cervical cancer by chrysotoxine, presenting new insights into the application of traditional Chinese medicine for fighting CC
The sound of silence
Self-media entrepreneurs from marginalised communities face unique challenges in the rapidly evolving global creative industries. This study examines the lived experiences of Deaf creators on Douyin, China’s leading short-video platform, highlighting how they navigate the socio-technical and economic pressures shaping their labour experiences. Drawing on the ethnographic approach, we uncover the tension between the platform’s promise of visibilit…
Genetic prediction of micronutrient levels and the risk of multiple system atrophy
Multiple system atrophy (MSA) is a fatal neurodegenerative disorder of elusive pathogenesis, and observational links to micronutrients are prone to confounding. Mendelian randomization (MR) uses genetic variants as instrumental variables to infer causality, minimizing confounding and reverse causation by mimicking randomized controlled trials. We performed a two-sample MR analysis using summary statistics from large-scale genome-wide association …
Medicine (6 works) · Biology (5 works) · Internal Medicine (5 works) · Pharmacology (5 works) · Disease (4 works) · Biochemistry (3 works) · Chemistry (3 works) · Geography (3 works) · Psychology (3 works) · Apoptosis (2 works)