Eric Kodish
Biographic Data
| ID | 6763520 |
|---|---|
| NAME | Eric Kodish |
| GIVEN NAMES | Eric |
| FAMILY NAME | Kodish |
| SIGNATURE | KODISH E |
| AFFILIATIONS | Cleveland Clinic |
| VERIFIED | No |
| TOTAL WORKS | 19 |
| TOTAL CITATIONS | 2 |
| AUTHOR COUNT | 19 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1999 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Recruitment Techniques Used for Clinical Trials and the Potential Impact of Nudges
While clinical trials are essential to improving public health, little research has examined the range of recruitment techniques used or whether they involve behavioral nudges. Behavioral nudges have been defined as "any aspect of the choice architecture [the manner in which options are presented] that alters people's behavior in a predictable way without forbidding any options or significantly changing their economic incentives"; these may influ…
Therapeutic Misperceptions in Early‐Phase Cancer Trials
Appropriate enrollment in early-phase clinical trials demands that potential research participants understand and appreciate critical study-related information, because discrepancies in understanding or appreciation can potentially invalidate informed consent to participate in research. Four terms were previously developed to categorize these discrepancies: therapeutic "misconception," "therapeutic misestimation," "therapeutic optimism," and "unr…
Ethical Issues in the Use of Nudges to Obtain Informed Consent for Biomedical Research
“What's in a name?” CAR‐T Gene Therapy
With all due respect to Shakespeare, the impact of nomenclature should not be underestimated. Words are both effective and affective. They send a signal to the listener but may have an even more pronounced effect on the mind of the speaker. During a four-year stint I finished in 2010 on the National Institutes of Health Recombinant DNA Advisory Committee, the committee was repeatedly reminded that we should not speak of “gene therapy.” “Gene tran…
Decision‐Making for an Incapacitated Pregnant Patient
Decisions about continuing or terminating a pregnancy touch on profound, individualized questions about bodily integrity, reproductive autonomy, deeply held values regarding one's capacity for parenthood, and, in the case of a high‐risk pregnancy, the risks one is willing to take to have a baby. So far as possible, reproductive decisions are made between a patient, in some cases her partner, and her medical provider. However, this standard framew…
The Limits of Informed Consent for an Overwhelmed Patient
In this paper, we examine the limits of informed consent with particular focus on ways in which various factors can overwhelm decision-making capacity. We introduce overwhelm as a phenomenon commonly experienced by patients in clinical settings and distinguish between emotional overwhelm and informational overload. We argue that in these situations, a clinician's primary duty is prevention of harm and suggest ways in which clinicians can discharg…
Reuniting Through the Medical Humanities
Meaning Preordained or Meant To Be MK: My entry into the field of medical humanities at Northeast Ohio Medical University (NEOMED) in 1981 places me in the second generation of those to enter a field whose roots go back to 1960 Although not part of the initial wave of immigrants to the shores of this new multi-(or for some, trans-) disciplinary academic endeavor, the second wave was still a time when many of us from disparate fields-my training i…
Laws that Conflict with the Ethics of Medicine
This past July, five professional societies, whose members together provide the majority of clinical care in the United States, published a statement objecting to “inappropriate legislative interference” with the physician‐patient relationship and reiterated the importance of “putting patients’ best interests first.” Such a collective response is helpful, but given the apparently growing interest among legislators in legislating aspects of physic…
Quality Attestation for Clinical Ethics Consultants
Clinical ethics consultation is largely outside the scope of regulation and oversight, despite its importance. For decades, the bioethics community has been unable to reach a consensus on whether there should be accountability in this work, as there is for other clinical activities that influence the care of patients. The American Society for Bioethics and Humanities, the primary society of bioethicists and scholars in the medical humanities and …
Minors' Right to Know and Therapeutic Privilege
There is evidence that children who are unaware of their life-threatening diagnoses do not experience any less distress and anxiety than those who are told, and in some cases they may actually experience more
Negotiating Decisions during Informed Consent for Pediatric Phase I Oncology Trials
During informed consent conferences (ICCs) for Phase I trials, oncologists must present complex information while addressing concerns. Research on communication that evolves during ICCs remains largely unexplored. We examined communication during ICCs for pediatric Phase I cancer trials using a stratified random sample from six pediatric cancer centers. A grounded theory approach identified key communication steps and factors influencing the nego…
Role of Independent Advocates for Research Subjects Who Are Child Wards of the State
Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit. Virtual Mentor is a monthly bioethics journal published by the American Medical Association
Helping Patients Decide Whether to Participate in Clinical Trials
Case "I've been feeling miserable lately, and I haven't been able to eat much at all," Mr. Brooks said, wincing as he shifted on the exam table. "Well, end-stage colon cancer is a pretty nasty disease," Dr. Winston, his primary care physician of 15 years, replied softly. "And I understand from your chart that the masses in your liver and lungs haven't gotten any smaller since your last round of chemo
Recommending Randomized Trials for Pediatric Leukemia
Physicians' presentation of treatment options in a non-coercive manner is critical for informed consent for participation in randomized clinical trials (RCTs). This study examined discrepancies between observer and physician report of treatment recommendations for pediatric leukemia RCTs. This study also assessed relationships between recommendations and decisions to participate in RCTs. Participants were 104 parents of children with leukemia and…
Conducting Empirical Research on Informed Consent
Greg A. Sachs, Gavin W. Hougham, Jeremy Sugarman, Patricia Agre, Marion E. Broome, Gail Geller, Nancy Kass, Eric Kodish, Jim Mintz, Laura W. Roberts, Pamela Sankar, Laura A. Siminoff, James Sorenson, Anita Weiss, Conducting Empirical Research on Informed Consent: Challenges and Questions, IRB: Ethics & Human Research, Vol. 25, No. 5, Supplement (Sep. - Oct., 2003), pp. S4-S10
Informing Study Participants of Research Results
Children in Research
Marion E. Broome, Eric Kodish, Gail Geller, Laura A. Siminoff, Children in Research: New Perspectives and Practices for Informed Consent, IRB: Ethics & Human Research, Vol. 25, No. 5, Supplement (Sep. - Oct., 2003), pp. S20-S25
Phase I Cancer Trials
Case Study
Baby Aaron was brought to the children's hospital emergency department at three months of age. His parents, members of the Amish community, told the ER doctor that the baby seemed to be having trouble breathing and was not growing well. After examining the baby, the physician was suspicious of congestive heart failure. An echocardiogram demonstrated significant congenital heart disease. A pediatric cardiologist was consulted. She informed the par…
Negotiating Decisions during Informed Consent for Pediatric Phase I Oncology Trials
During informed consent conferences (ICCs) for Phase I trials, oncologists must present complex information while addressing concerns. Research on communication that evolves during ICCs remains largely unexplored. We examined communication during ICCs for pediatric Phase I cancer trials using a stratified random sample from six pediatric cancer centers. A grounded theory approach identified key communication steps and factors influencing the nego…
Case Study
Baby Aaron was brought to the children's hospital emergency department at three months of age. His parents, members of the Amish community, told the ER doctor that the baby seemed to be having trouble breathing and was not growing well. After examining the baby, the physician was suspicious of congestive heart failure. An echocardiogram demonstrated significant congenital heart disease. A pediatric cardiologist was consulted. She informed the par…
Phase I Cancer Trials
Conducting Empirical Research on Informed Consent
Greg A. Sachs, Gavin W. Hougham, Jeremy Sugarman, Patricia Agre, Marion E. Broome, Gail Geller, Nancy Kass, Eric Kodish, Jim Mintz, Laura W. Roberts, Pamela Sankar, Laura A. Siminoff, James Sorenson, Anita Weiss, Conducting Empirical Research on Informed Consent: Challenges and Questions, IRB: Ethics & Human Research, Vol. 25, No. 5, Supplement (Sep. - Oct., 2003), pp. S4-S10
Informing Study Participants of Research Results
Children in Research
Marion E. Broome, Eric Kodish, Gail Geller, Laura A. Siminoff, Children in Research: New Perspectives and Practices for Informed Consent, IRB: Ethics & Human Research, Vol. 25, No. 5, Supplement (Sep. - Oct., 2003), pp. S20-S25
Helping Patients Decide Whether to Participate in Clinical Trials
Case "I've been feeling miserable lately, and I haven't been able to eat much at all," Mr. Brooks said, wincing as he shifted on the exam table. "Well, end-stage colon cancer is a pretty nasty disease," Dr. Winston, his primary care physician of 15 years, replied softly. "And I understand from your chart that the masses in your liver and lungs haven't gotten any smaller since your last round of chemo
Recommending Randomized Trials for Pediatric Leukemia
Physicians' presentation of treatment options in a non-coercive manner is critical for informed consent for participation in randomized clinical trials (RCTs). This study examined discrepancies between observer and physician report of treatment recommendations for pediatric leukemia RCTs. This study also assessed relationships between recommendations and decisions to participate in RCTs. Participants were 104 parents of children with leukemia and…
Role of Independent Advocates for Research Subjects Who Are Child Wards of the State
Specific advocate guidelines are needed for the protection of children in state custody who are potential research subjects in trials that would expose them to greater-than-minimal risk but also hold the prospect of direct benefit. Virtual Mentor is a monthly bioethics journal published by the American Medical Association
Negotiating Decisions during Informed Consent for Pediatric Phase I Oncology Trials
During informed consent conferences (ICCs) for Phase I trials, oncologists must present complex information while addressing concerns. Research on communication that evolves during ICCs remains largely unexplored. We examined communication during ICCs for pediatric Phase I cancer trials using a stratified random sample from six pediatric cancer centers. A grounded theory approach identified key communication steps and factors influencing the nego…
Quality Attestation for Clinical Ethics Consultants
Clinical ethics consultation is largely outside the scope of regulation and oversight, despite its importance. For decades, the bioethics community has been unable to reach a consensus on whether there should be accountability in this work, as there is for other clinical activities that influence the care of patients. The American Society for Bioethics and Humanities, the primary society of bioethicists and scholars in the medical humanities and …
Minors' Right to Know and Therapeutic Privilege
There is evidence that children who are unaware of their life-threatening diagnoses do not experience any less distress and anxiety than those who are told, and in some cases they may actually experience more
Laws that Conflict with the Ethics of Medicine
This past July, five professional societies, whose members together provide the majority of clinical care in the United States, published a statement objecting to “inappropriate legislative interference” with the physician‐patient relationship and reiterated the importance of “putting patients’ best interests first.” Such a collective response is helpful, but given the apparently growing interest among legislators in legislating aspects of physic…
Reuniting Through the Medical Humanities
Meaning Preordained or Meant To Be MK: My entry into the field of medical humanities at Northeast Ohio Medical University (NEOMED) in 1981 places me in the second generation of those to enter a field whose roots go back to 1960 Although not part of the initial wave of immigrants to the shores of this new multi-(or for some, trans-) disciplinary academic endeavor, the second wave was still a time when many of us from disparate fields-my training i…
The Limits of Informed Consent for an Overwhelmed Patient
In this paper, we examine the limits of informed consent with particular focus on ways in which various factors can overwhelm decision-making capacity. We introduce overwhelm as a phenomenon commonly experienced by patients in clinical settings and distinguish between emotional overwhelm and informational overload. We argue that in these situations, a clinician's primary duty is prevention of harm and suggest ways in which clinicians can discharg…
“What's in a name?” CAR‐T Gene Therapy
With all due respect to Shakespeare, the impact of nomenclature should not be underestimated. Words are both effective and affective. They send a signal to the listener but may have an even more pronounced effect on the mind of the speaker. During a four-year stint I finished in 2010 on the National Institutes of Health Recombinant DNA Advisory Committee, the committee was repeatedly reminded that we should not speak of “gene therapy.” “Gene tran…
Decision‐Making for an Incapacitated Pregnant Patient
Decisions about continuing or terminating a pregnancy touch on profound, individualized questions about bodily integrity, reproductive autonomy, deeply held values regarding one's capacity for parenthood, and, in the case of a high‐risk pregnancy, the risks one is willing to take to have a baby. So far as possible, reproductive decisions are made between a patient, in some cases her partner, and her medical provider. However, this standard framew…
Therapeutic Misperceptions in Early‐Phase Cancer Trials
Appropriate enrollment in early-phase clinical trials demands that potential research participants understand and appreciate critical study-related information, because discrepancies in understanding or appreciation can potentially invalidate informed consent to participate in research. Four terms were previously developed to categorize these discrepancies: therapeutic "misconception," "therapeutic misestimation," "therapeutic optimism," and "unr…
Ethical Issues in the Use of Nudges to Obtain Informed Consent for Biomedical Research
Recruitment Techniques Used for Clinical Trials and the Potential Impact of Nudges
While clinical trials are essential to improving public health, little research has examined the range of recruitment techniques used or whether they involve behavioral nudges. Behavioral nudges have been defined as "any aspect of the choice architecture [the manner in which options are presented] that alters people's behavior in a predictable way without forbidding any options or significantly changing their economic incentives"; these may influ…
Medicine (17 works) · Psychology (13 works) · Ethics in Clinical Research (10 works) · Ethics and Legal Issues in Pediatric Healthcare (9 works) · Law (8 works) · Political science (8 works) · Alternative medicine (6 works) · Engineering ethics (6 works) · Informed consent (6 works) · Sociology (6 works)