Jean Gaudart
Biographic Data
| ID | 6921616 |
|---|---|
| NAME | Jean Gaudart |
| GIVEN NAMES | Jean |
| FAMILY NAME | Gaudart |
| SIGNATURE | GAUDART J |
| AFFILIATIONS | Inserm |
| ORCID | 0000-0001-9006-5729 |
| VERIFIED | Yes |
| TOTAL WORKS | 24 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 24 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2006 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Distribution and determinants of Covid-19 seroprevalence in a hard-to-access health district in Mali
In November 2023, three years after the onset of the pandemic, Mali officially recorded 33,160 confirmed COVID-19 cases and 743 related deaths. Tombouctou health district, following Bamako, the capital city, emerged as the second major hotspot with over 532 confirmed cases. However, these figures likely underestimate the true scale of the epidemic due to limited healthcare access and diagnostic capacity. This study aimed to describe the early tra…
Geo-epidemiological risk stratification to select malaria interventions, case of Mali
Malaria is a public health threat in Mali, with high morbidity (37%) and mortality (25%) rates. Malaria risk stratification is needed to identify different risk transmission and select interventions, especially in resource-limited contexts. For the new National Strategic Plan, we updated stratification with World Health Organization (WHO) recommendation and presents the selection of interventions based on stratification. Data collection covered a…
Determinants of Sars-CoV-2 infection across three sentinels sites in Benin during 2021
In the context of the COVID-19 pandemic, Benin, like other regions in sub-Saharan Africa and around the world, has been grappling with a public health crisis since march 2020. The country responded to this crisis by implementing adaptive response measures. The STREESCO project is part of this dynamic effort, strengthening epidemiological surveillance at three sentinel sites. This study thoroughly examines the determinants of SARS-CoV-2 infection.…
Impact of seasonal malaria chemoprevention timing on clinical malaria incidence dynamics in the Kedougou region, Senegal
Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine is recommended by the World Health Organization since 2012 for clinical malaria prevention in children in the Sahelian region of Africa. In Senegal, SMC implementation began in 2013 and is given to children under 10 years old. This study aimed to describe clinical malaria incidence in the general population during routine SMC implementation and to analyse how SM…
Reviving health mediation during the Covid-19 crisis and beyond
Introduction: In 2020, during France's COVID-19 response, healthcare professionals from a hospital and an association initiated health mediation interventions in Marseille's vulnerable neighbourhoods, funded by the regional health authorities. This mixed method research evaluates the CORHESAN program that lasted until June 2022. Methods: We examined CORHESAN documents and reports, conducted interviews, and analysed activity data, comparing it to …
Sars-CoV-2 seroprevalence among Beninese pregnant women in the third year of the pandemic
NCT06170320 (retrospectively registered on December 21, 2023)
Geographical coverage of Sars-CoV-2 screening and care centers in Haiti
This study highlights the weakness of SARS-CoV-2 screening and care system in Haiti, particularly in the poorest communes, suggesting that the number of COVID-19 cases and deaths were probably greatly underestimated
Social deprivation and Sars-CoV-2 testing
Background: Testing was the cornerstone of the COVID-19 epidemic response in most countries until vaccination became available for the general population. Social inequalities generally affect access to healthcare and health behaviors, and COVID-19 was rapidly shown to impact deprived population more drastically. In support of the regional health agency in Provence-Alpes-Côte d'Azur (PACA) in South-Eastern France, we analyzed the relationship betw…
Transmission of Sars-CoV-2 during indoor clubbing events
Introduction: The SARS-CoV-2 pandemic led to the implementation of several non-pharmaceutical interventions (NPIs), from closings of bars and restaurants to curfews and lockdowns. Vaccination campaigns started hoping it could efficiently alleviate NPI. The primary objective of the "Indoor Transmission of COVID-19" (ITOC) study is to determine among a fully vaccinated population the relative risk of SARS-CoV-2 transmission during one indoor clubbi…
Residential Mobility of a Cohort of Homeless People in Times of Crisis
Most vulnerable individuals are particularly affected by the COVID-19 pandemic. This study takes place in a large city in France. The aim of this study is to describe the mobility of the homeless population at the beginning of the health crisis and to analyze its impact in terms of COVID-19 prevalence. From June to August 2020 and September to December 2020, 1272 homeless people were invited to be tested for SARS-CoV-2 antibodies and virus and co…
Spatio-Temporal Variability of Malaria Incidence in the Health District of Kati, Mali, 2015–2019
Our study confirmed the important variability of malaria incidence and found malaria transmission to be associated with several meteorological and environmental factors in the Kati district. The persistence of malaria during the dry season and the spatio-temporal variability of malaria hotspots reinforce the need for innovative and targeted strategies
Accuracy of malaria diagnostic tests performed on non-invasively collected samples
Spatio-Temporal Dynamics of Plasmodium falciparum and Plasmodium vivax in French Guiana
Aims: This study examines the dynamics of malaria as influenced by meteorological factors in French Guiana from 2005 to 2019. It explores spatial hotspots of malaria transmission and aims to determine the factors associated with variation of hotspots with time. Methods : Data for individual malaria cases came from the surveillance system of the Delocalized Centers for Prevention and Care (CDPS) ( n = 17) from 2005-2019. Meteorological data was ac…
Targeting Malaria Hotspots to Reduce Transmission Incidence in Senegal
In central Senegal, malaria incidence declined in response to scaling-up of control measures from 2000 to 2010 and has since remained stable, making elimination unlikely in the short term. Additional control measures are needed to reduce transmission. We simulated chemoprophylaxis interventions targeting malaria hotspots using a metapopulation mathematical model, based on a differential-equation framework and incorporating human mobility. The mod…
Geo-Epidemiology of Malaria at the Health Area Level, Dire Health District, Mali, 2013–2017
Background : According to the World Health Organization, there were more than 228 million cases of malaria globally in 2018, with 93% of cases occurring in Africa; in Mali, a 13% increase in the number of cases was observed between 2015 and 2018; this study aimed to evaluate the impact of meteorological and environmental factors on the geo-epidemiology of malaria in the health district of Dire, Mali. Methods : Meteorological and environmental var…
Spatio-Temporal Dynamic of Malaria Incidence
Malaria transmission largely depends on environmental, climatic, and hydrological conditions. In Mali, malaria epidemiological patterns are nested within three ecological zones. This study aimed at assessing the relationship between those conditions and the incidence of malaria in Dangassa and Koila, Mali. Malaria data was collected through passive case detection at community health facilities of each study site from June 2015 to January 2017. Cl…
Application of Functional Data Analysis to Identify Patterns of Malaria Incidence, to Guide Targeted Control Strategies
We introduce an approach based on functional data analysis to identify patterns of malaria incidence to guide effective targeting of malaria control in a seasonal transmission area. Using functional data method, a smooth function (functional data or curve) was fitted from the time series of observed malaria incidence for each of 575 villages in west-central Senegal from 2008 to 2012. These 575 smooth functions were classified using hierarchical c…
Predicting Malaria Transmission Dynamics in Dangassa, Mali
Mali aims to reach the pre-elimination stage of malaria by the next decade. This study used functional regression models to predict the incidence of malaria as a function of past meteorological patterns to better prevent and to act proactively against impending malaria outbreaks. All data were collected over a five-year period (2012-2017) from 1400 persons who sought treatment at Dangassa's community health center. Rainfall, temperature, humidity…
How to Estimate Optimal Malaria Readiness Indicators at Health-District Level
One of the major contributors of malaria-related deaths in Sub-Saharan African countries is the limited accessibility to quality care. In these countries, malaria control activities are implemented at the health-district level (operational entity of the national health system), while malaria readiness indicators are regionally representative. This study provides an approach for estimating health district-level malaria readiness indicators from su…
Two-Year Scale-Up of Seasonal Malaria Chemoprevention Reduced Malaria Morbidity among Children in the Health District of Koutiala, Mali
SMC significantly reduced frequency of malaria infection, clinical malaria and anemia two years after SMC scale-up in Koutiala
Socioeconomic and environmental factors associated with malaria hotspots in the Nanoro demographic surveillance area, Burkina Faso
With limited resources and spatio-temporal heterogeneity of malaria in developing countries, it is still difficult to assess the real impact of socioeconomic and environmental factors in order to set up targeted campaigns against malaria at an accurate scale. Our goal was to detect malaria hotspots in rural area and assess the extent to which household socioeconomic status and meteorological recordings may explain the occurrence and evolution of …
Cementochronology
Influenza-attributable deaths in south-eastern France (1999 to 2010)
Since most of the influenza mortality is commonly observed in the elderly group (>65 year-old), the moderate elderly mortality during the 2009 pandemic period has impacted the total mortality, and has resulted in a reduced total mortality despite an increased mortality in the young age group. Despite using identical parameters and the same approach as in a previously published study using an Austrian population sample, we observed a lower excess …
Space-time clustering of childhood malaria at the household level
This study showed that, although infection proportions tended to decrease, high-risk zones persisted in the village particularly near temporal backwaters. Analysis of this heterogeneity at the household scale by GIS methods lead to target preventive actions more accurately on the high-risk zones identified. This mapping of malaria risk makes it possible to orient control programs, treating the high-risk zones identified as a matter of priority, a…
Space-time clustering of childhood malaria at the household level
This study showed that, although infection proportions tended to decrease, high-risk zones persisted in the village particularly near temporal backwaters. Analysis of this heterogeneity at the household scale by GIS methods lead to target preventive actions more accurately on the high-risk zones identified. This mapping of malaria risk makes it possible to orient control programs, treating the high-risk zones identified as a matter of priority, a…
Influenza-attributable deaths in south-eastern France (1999 to 2010)
Since most of the influenza mortality is commonly observed in the elderly group (>65 year-old), the moderate elderly mortality during the 2009 pandemic period has impacted the total mortality, and has resulted in a reduced total mortality despite an increased mortality in the young age group. Despite using identical parameters and the same approach as in a previously published study using an Austrian population sample, we observed a lower excess …
Cementochronology
Socioeconomic and environmental factors associated with malaria hotspots in the Nanoro demographic surveillance area, Burkina Faso
With limited resources and spatio-temporal heterogeneity of malaria in developing countries, it is still difficult to assess the real impact of socioeconomic and environmental factors in order to set up targeted campaigns against malaria at an accurate scale. Our goal was to detect malaria hotspots in rural area and assess the extent to which household socioeconomic status and meteorological recordings may explain the occurrence and evolution of …
Targeting Malaria Hotspots to Reduce Transmission Incidence in Senegal
In central Senegal, malaria incidence declined in response to scaling-up of control measures from 2000 to 2010 and has since remained stable, making elimination unlikely in the short term. Additional control measures are needed to reduce transmission. We simulated chemoprophylaxis interventions targeting malaria hotspots using a metapopulation mathematical model, based on a differential-equation framework and incorporating human mobility. The mod…
Geo-Epidemiology of Malaria at the Health Area Level, Dire Health District, Mali, 2013–2017
Background : According to the World Health Organization, there were more than 228 million cases of malaria globally in 2018, with 93% of cases occurring in Africa; in Mali, a 13% increase in the number of cases was observed between 2015 and 2018; this study aimed to evaluate the impact of meteorological and environmental factors on the geo-epidemiology of malaria in the health district of Dire, Mali. Methods : Meteorological and environmental var…
Spatio-Temporal Dynamic of Malaria Incidence
Malaria transmission largely depends on environmental, climatic, and hydrological conditions. In Mali, malaria epidemiological patterns are nested within three ecological zones. This study aimed at assessing the relationship between those conditions and the incidence of malaria in Dangassa and Koila, Mali. Malaria data was collected through passive case detection at community health facilities of each study site from June 2015 to January 2017. Cl…
Application of Functional Data Analysis to Identify Patterns of Malaria Incidence, to Guide Targeted Control Strategies
We introduce an approach based on functional data analysis to identify patterns of malaria incidence to guide effective targeting of malaria control in a seasonal transmission area. Using functional data method, a smooth function (functional data or curve) was fitted from the time series of observed malaria incidence for each of 575 villages in west-central Senegal from 2008 to 2012. These 575 smooth functions were classified using hierarchical c…
Predicting Malaria Transmission Dynamics in Dangassa, Mali
Mali aims to reach the pre-elimination stage of malaria by the next decade. This study used functional regression models to predict the incidence of malaria as a function of past meteorological patterns to better prevent and to act proactively against impending malaria outbreaks. All data were collected over a five-year period (2012-2017) from 1400 persons who sought treatment at Dangassa's community health center. Rainfall, temperature, humidity…
How to Estimate Optimal Malaria Readiness Indicators at Health-District Level
One of the major contributors of malaria-related deaths in Sub-Saharan African countries is the limited accessibility to quality care. In these countries, malaria control activities are implemented at the health-district level (operational entity of the national health system), while malaria readiness indicators are regionally representative. This study provides an approach for estimating health district-level malaria readiness indicators from su…
Two-Year Scale-Up of Seasonal Malaria Chemoprevention Reduced Malaria Morbidity among Children in the Health District of Koutiala, Mali
SMC significantly reduced frequency of malaria infection, clinical malaria and anemia two years after SMC scale-up in Koutiala
Accuracy of malaria diagnostic tests performed on non-invasively collected samples
Spatio-Temporal Dynamics of Plasmodium falciparum and Plasmodium vivax in French Guiana
Aims: This study examines the dynamics of malaria as influenced by meteorological factors in French Guiana from 2005 to 2019. It explores spatial hotspots of malaria transmission and aims to determine the factors associated with variation of hotspots with time. Methods : Data for individual malaria cases came from the surveillance system of the Delocalized Centers for Prevention and Care (CDPS) ( n = 17) from 2005-2019. Meteorological data was ac…
Transmission of Sars-CoV-2 during indoor clubbing events
Introduction: The SARS-CoV-2 pandemic led to the implementation of several non-pharmaceutical interventions (NPIs), from closings of bars and restaurants to curfews and lockdowns. Vaccination campaigns started hoping it could efficiently alleviate NPI. The primary objective of the "Indoor Transmission of COVID-19" (ITOC) study is to determine among a fully vaccinated population the relative risk of SARS-CoV-2 transmission during one indoor clubbi…
Residential Mobility of a Cohort of Homeless People in Times of Crisis
Most vulnerable individuals are particularly affected by the COVID-19 pandemic. This study takes place in a large city in France. The aim of this study is to describe the mobility of the homeless population at the beginning of the health crisis and to analyze its impact in terms of COVID-19 prevalence. From June to August 2020 and September to December 2020, 1272 homeless people were invited to be tested for SARS-CoV-2 antibodies and virus and co…
Spatio-Temporal Variability of Malaria Incidence in the Health District of Kati, Mali, 2015–2019
Our study confirmed the important variability of malaria incidence and found malaria transmission to be associated with several meteorological and environmental factors in the Kati district. The persistence of malaria during the dry season and the spatio-temporal variability of malaria hotspots reinforce the need for innovative and targeted strategies
Social deprivation and Sars-CoV-2 testing
Background: Testing was the cornerstone of the COVID-19 epidemic response in most countries until vaccination became available for the general population. Social inequalities generally affect access to healthcare and health behaviors, and COVID-19 was rapidly shown to impact deprived population more drastically. In support of the regional health agency in Provence-Alpes-Côte d'Azur (PACA) in South-Eastern France, we analyzed the relationship betw…
Reviving health mediation during the Covid-19 crisis and beyond
Introduction: In 2020, during France's COVID-19 response, healthcare professionals from a hospital and an association initiated health mediation interventions in Marseille's vulnerable neighbourhoods, funded by the regional health authorities. This mixed method research evaluates the CORHESAN program that lasted until June 2022. Methods: We examined CORHESAN documents and reports, conducted interviews, and analysed activity data, comparing it to …
Sars-CoV-2 seroprevalence among Beninese pregnant women in the third year of the pandemic
NCT06170320 (retrospectively registered on December 21, 2023)
Geographical coverage of Sars-CoV-2 screening and care centers in Haiti
This study highlights the weakness of SARS-CoV-2 screening and care system in Haiti, particularly in the poorest communes, suggesting that the number of COVID-19 cases and deaths were probably greatly underestimated
Distribution and determinants of Covid-19 seroprevalence in a hard-to-access health district in Mali
In November 2023, three years after the onset of the pandemic, Mali officially recorded 33,160 confirmed COVID-19 cases and 743 related deaths. Tombouctou health district, following Bamako, the capital city, emerged as the second major hotspot with over 532 confirmed cases. However, these figures likely underestimate the true scale of the epidemic due to limited healthcare access and diagnostic capacity. This study aimed to describe the early tra…
Geo-epidemiological risk stratification to select malaria interventions, case of Mali
Malaria is a public health threat in Mali, with high morbidity (37%) and mortality (25%) rates. Malaria risk stratification is needed to identify different risk transmission and select interventions, especially in resource-limited contexts. For the new National Strategic Plan, we updated stratification with World Health Organization (WHO) recommendation and presents the selection of interventions based on stratification. Data collection covered a…
Determinants of Sars-CoV-2 infection across three sentinels sites in Benin during 2021
In the context of the COVID-19 pandemic, Benin, like other regions in sub-Saharan Africa and around the world, has been grappling with a public health crisis since march 2020. The country responded to this crisis by implementing adaptive response measures. The STREESCO project is part of this dynamic effort, strengthening epidemiological surveillance at three sentinel sites. This study thoroughly examines the determinants of SARS-CoV-2 infection.…
Impact of seasonal malaria chemoprevention timing on clinical malaria incidence dynamics in the Kedougou region, Senegal
Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine is recommended by the World Health Organization since 2012 for clinical malaria prevention in children in the Sahelian region of Africa. In Senegal, SMC implementation began in 2013 and is given to children under 10 years old. This study aimed to describe clinical malaria incidence in the general population during routine SMC implementation and to analyse how SM…
Medicine (19 works) · Environmental health (16 works) · Geography (16 works) · Malaria (13 works) · Demography (12 works) · Malaria Research and Control (12 works) · COVID-19 epidemiological studies (11 works) · Population (11 works) · Immunology (10 works) · Mosquito-borne diseases and control (10 works)