Matthew O Wiens
Biographic Data
| ID | 7008588 |
|---|---|
| NAME | Matthew O Wiens |
| GIVEN NAMES | Matthew |
| FAMILY NAME | O Wiens |
| SIGNATURE | WIENS M O |
| AFFILIATIONS | University of British Columbia |
| ORCID | 0000-0002-3287-5181 |
| VERIFIED | Yes |
| TOTAL WORKS | 13 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 13 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2016 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
Diverging pathways
BACKGROUND: Mortality and readmission rates are high in low-income countries following hospital discharge; however, few studies have studied the relationship between these outcomes. Hospital readmission is a complex outcome as it reflects illness severity and health-seeking behaviour. This study aims to better understand the heterogeneous nature of hospital readmission, especially as it pertains to mortality. METHODS: Secondary analysis of a pros…
Discharge policies and care practices for children with suspected sepsis
Under-five children in low- and middle-income countries remain at high risk of death after hospital discharge. However, few studies have systematically assessed discharge processes or facility readiness to support safe transitions of care. This study aimed to assess health facility readiness to provide pediatric discharge care for children under five years of age and current discharge practices in a nationally representative sample of health faci…
Repeatability of RRate measurements in children during triage in two Ugandan hospitals
Pneumonia is the leading cause of death in children globally. In low- and middle-income countries (LMICs) pneumonia diagnosis relies on accurate assessment of respiratory rate, which can be unreliable when completed by nurses with less-advanced training. To inform more accurate measurements, we investigate the repeatability of the RRate app used by nurses in Ugandan district hospitals. This secondary analysis included 3,679 children aged 0–5 year…
Validation of a risk-prediction model for pediatric post-discharge mortality after hospital admission for infection in Rwanda
Mortality following hospital discharge remains a significant threat to child health, particularly in resource-limited settings. The Smart Discharges risk-prediction models use simple clinical, socio-behavioral, and point-of-care lab test variables to successfully predict children at the highest risk of death after hospital admission for infection to guide a risk-based approach to post-discharge care. In Rwanda, we externally validated five models…
Post-discharge mortality in suspected pediatric sepsis
Post-discharge death is a key contributor to pediatric mortality in sub-Saharan Africa. To address this period’s morbidity and mortality, evidence is needed to inform resource prioritization and policy development. No studies have been conducted in Rwanda, limiting understanding of post-discharge mortality. This study aimed to determine the incidence of and risk factors for post-discharge mortality among children under five admitted with suspecte…
Prediction models for post-discharge mortality among under-five children with suspected sepsis in Uganda
In many low-income countries, over five percent of hospitalized children die following hospital discharge. The lack of available tools to identify those at risk of post-discharge mortality has limited the ability to make progress towards improving outcomes. We aimed to develop algorithms designed to predict post-discharge mortality among children admitted with suspected sepsis. Four prospective cohort studies of children in two age groups (0–6 an…
The epidemiology and risk factors for postnatal complications among postpartum women and newborns in southwestern Uganda
Sub-Saharan Africa accounts for two-thirds of the global burden of maternal and newborn deaths. Adverse outcomes among postpartum women and newborns occurring in the first six weeks of life are often related, though data co-examining patients are limited. This study is an exploratory analysis describing the epidemiology of postnatal complications among postpartum women and newborns following facility birth and discharge in Mbarara, Uganda. This s…
Transitions from hospital to home
The World Health Organization (WHO) Integrated Management of Childhood Illness (IMCI) guidelines recognize the importance of discharge planning to ensure continuation of care at home and appropriate follow-up. However, insufficient attention has been paid to post discharge planning in many hospitals contributing to poor implementation. To understand the reasons for suboptimal discharge, we evaluated the pediatric discharge process from hospital a…
World Health Organization Danger Signs to predict bacterial sepsis in young infants
Bacterial sepsis is generally a major concern in ill infants. To help triaging decisions by front-line health workers in these situations, the World Health Organization (WHO) has developed danger signs (DS). The objective of this study was to evaluate the extent to which nine DS predict bacterial sepsis in young infants presenting with suspected sepsis in a low-income country setting. The study pragmatically evaluated nine DS in infants younger t…
“If you have light, your heart will be at peace”
Background: Expanding electrification and access to other clean and affordable energy, such as solar energy, is a critical component of the Sustainable Development Goals, particularly in sub-Saharan Africa where 70% of people are energy insecure. Intervention trials related to access or less polluting household energy alternatives have typically focused on air quality and biological outcomes rather than on how an intervention affects the end user…
Anticipating the future
In low-income and middle-income countries, most patients with febrile illnesses present to peripheral levels of the health system where diagnostic capacity is very limited. In these contexts, accurate risk stratification can be particularly impactful, helping to guide allocation of scarce resources to ensure timely and tailored care. However, reporting of prognostic research is often imprecise and few prognostic tests or algorithms are translated…
Use, cost-effectiveness, and end user perspectives of a home solar lighting intervention in rural Uganda
Energy poverty is prevalent in resource-limited settings, leading households to use inefficient fuels and appliances that contribute to household air pollution. Randomized controlled trials of household energy interventions in low and middle income countries have largely focused on cooking services. Less is known about the adoption and impact of clean lighting interventions. We conducted an explanatory sequential mixed methods study as part of a …
Prevalence of Ethanol Use Among Pregnant Women in Southwestern Uganda
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Prevalence of Ethanol Use Among Pregnant Women in Southwestern Uganda
Anticipating the future
In low-income and middle-income countries, most patients with febrile illnesses present to peripheral levels of the health system where diagnostic capacity is very limited. In these contexts, accurate risk stratification can be particularly impactful, helping to guide allocation of scarce resources to ensure timely and tailored care. However, reporting of prognostic research is often imprecise and few prognostic tests or algorithms are translated…
Use, cost-effectiveness, and end user perspectives of a home solar lighting intervention in rural Uganda
Energy poverty is prevalent in resource-limited settings, leading households to use inefficient fuels and appliances that contribute to household air pollution. Randomized controlled trials of household energy interventions in low and middle income countries have largely focused on cooking services. Less is known about the adoption and impact of clean lighting interventions. We conducted an explanatory sequential mixed methods study as part of a …
Transitions from hospital to home
The World Health Organization (WHO) Integrated Management of Childhood Illness (IMCI) guidelines recognize the importance of discharge planning to ensure continuation of care at home and appropriate follow-up. However, insufficient attention has been paid to post discharge planning in many hospitals contributing to poor implementation. To understand the reasons for suboptimal discharge, we evaluated the pediatric discharge process from hospital a…
World Health Organization Danger Signs to predict bacterial sepsis in young infants
Bacterial sepsis is generally a major concern in ill infants. To help triaging decisions by front-line health workers in these situations, the World Health Organization (WHO) has developed danger signs (DS). The objective of this study was to evaluate the extent to which nine DS predict bacterial sepsis in young infants presenting with suspected sepsis in a low-income country setting. The study pragmatically evaluated nine DS in infants younger t…
“If you have light, your heart will be at peace”
Background: Expanding electrification and access to other clean and affordable energy, such as solar energy, is a critical component of the Sustainable Development Goals, particularly in sub-Saharan Africa where 70% of people are energy insecure. Intervention trials related to access or less polluting household energy alternatives have typically focused on air quality and biological outcomes rather than on how an intervention affects the end user…
Prediction models for post-discharge mortality among under-five children with suspected sepsis in Uganda
In many low-income countries, over five percent of hospitalized children die following hospital discharge. The lack of available tools to identify those at risk of post-discharge mortality has limited the ability to make progress towards improving outcomes. We aimed to develop algorithms designed to predict post-discharge mortality among children admitted with suspected sepsis. Four prospective cohort studies of children in two age groups (0–6 an…
The epidemiology and risk factors for postnatal complications among postpartum women and newborns in southwestern Uganda
Sub-Saharan Africa accounts for two-thirds of the global burden of maternal and newborn deaths. Adverse outcomes among postpartum women and newborns occurring in the first six weeks of life are often related, though data co-examining patients are limited. This study is an exploratory analysis describing the epidemiology of postnatal complications among postpartum women and newborns following facility birth and discharge in Mbarara, Uganda. This s…
Diverging pathways
BACKGROUND: Mortality and readmission rates are high in low-income countries following hospital discharge; however, few studies have studied the relationship between these outcomes. Hospital readmission is a complex outcome as it reflects illness severity and health-seeking behaviour. This study aims to better understand the heterogeneous nature of hospital readmission, especially as it pertains to mortality. METHODS: Secondary analysis of a pros…
Discharge policies and care practices for children with suspected sepsis
Under-five children in low- and middle-income countries remain at high risk of death after hospital discharge. However, few studies have systematically assessed discharge processes or facility readiness to support safe transitions of care. This study aimed to assess health facility readiness to provide pediatric discharge care for children under five years of age and current discharge practices in a nationally representative sample of health faci…
Repeatability of RRate measurements in children during triage in two Ugandan hospitals
Pneumonia is the leading cause of death in children globally. In low- and middle-income countries (LMICs) pneumonia diagnosis relies on accurate assessment of respiratory rate, which can be unreliable when completed by nurses with less-advanced training. To inform more accurate measurements, we investigate the repeatability of the RRate app used by nurses in Ugandan district hospitals. This secondary analysis included 3,679 children aged 0–5 year…
Validation of a risk-prediction model for pediatric post-discharge mortality after hospital admission for infection in Rwanda
Mortality following hospital discharge remains a significant threat to child health, particularly in resource-limited settings. The Smart Discharges risk-prediction models use simple clinical, socio-behavioral, and point-of-care lab test variables to successfully predict children at the highest risk of death after hospital admission for infection to guide a risk-based approach to post-discharge care. In Rwanda, we externally validated five models…
Post-discharge mortality in suspected pediatric sepsis
Post-discharge death is a key contributor to pediatric mortality in sub-Saharan Africa. To address this period’s morbidity and mortality, evidence is needed to inform resource prioritization and policy development. No studies have been conducted in Rwanda, limiting understanding of post-discharge mortality. This study aimed to determine the incidence of and risk factors for post-discharge mortality among children under five admitted with suspecte…
Medicine (11 works) · Global Maternal and Child Health (7 works) · Internal Medicine (6 works) · Sepsis Diagnosis and Treatment (6 works) · Pediatrics (5 works) · Business (4 works) · Cohort study (4 works) · Emergency and Acute Care Studies (4 works) · Environmental health (4 works) · Health care (4 works)