Miguel Ángel García-Bereguiain
Biographic Data
| ID | 7009229 |
|---|---|
| NAME | Miguel Ángel García-Bereguiain |
| GIVEN NAMES | Miguel Ángel |
| FAMILY NAME | García-Bereguiain |
| SIGNATURE | GARCÍA-BEREGUIAIN M Á |
| AFFILIATIONS | Universidad de Las Américas |
| ORCID | 0000-0003-0025-3609 |
| VERIFIED | Yes |
| TOTAL WORKS | 19 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 7 |
| FIRST PUBLICATION YEAR | 2021 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Acceptability of tongue swabs for tuberculosis screening in migrant settings in northern Italy
Human migrations, driven by economic hardship, conflict, and climate change, complicate the global fight against tuberculosis (TB). New strategies are needed to improve the screening of migrants for active TB disease. Current sputum-based testing methods are logistically challenging in many settings. Alternative sampling with tongue swabs is designed to be easier than sputum collection and exhibits acceptable accuracy. This study characterized th…
Coinfections and superinfections in critically ill Covid-19 patients in Ecuador
Introduction The COVID-19 pandemic has deeply affected Latin America and Ecuador. Coinfections and superinfections increase the risk of morbidity and mortality in COVID-19 patients. This study examined co-infections and superinfections in critically ill COVID-19 patients admitted to the ICU of a tertiary hospital in Ecuador. Methods A cross-sectional study was conducted from February to August 2021, including patients with a confirmed SARS-CoV-2 …
Genomic surveillance of Sars-CoV-2 in the Andean Community (2020–2024)
Introduction: The COVID-19 pandemic has deeply affected Latin American countries, with countless COVID-19 cases and deaths. In countries like Peru, Colombia, Ecuador and Bolivia there was a collapse of the public health system, and the lack of testing capacity did not allow to control the spread of SARS-CoV-2 during the first year of the COVID-19 pandemic. After these dramatic beginnings, regional efforts focused on improving testing capacity and…
An intersectionality perspective on tuberculosis
Introduction: The Intersectionality approach to studying tuberculosis (TB) is a complex one. While historical data and indicators consistently suggest a positive correlation between social determinants, such as poverty, and TB mortality, the strength of this association varies across different regions and countries. Overcrowding and population density are also recognized as risk factors for TB transmission. Methods: In this study, we conducted a …
Population structure and antibiotic resistance profiles of Mycobacterium tuberculosis isolates from Ibadan, Nigeria (2019–2020)
Nigeria ranks as the sixth country globally and the first in Africa with the highest burden of tuberculosis (TB) infection. The emergence and spread of multidrug-resistant TB (MDR-TB) strains have posed significant challenges to effective disease management in the country. In this study, 55 Mycobacterium tuberculosis (MTB) isolates from patients attending a hospital in Ibadan city (Nigeria) were selected. MTB isolates were analyzed using PCR ampl…
Analyzing determinants of social practices in infectious diseases among Indigenous and Afro-Colombian communities
Infectious diseases pose major public health challenges worldwide, particularly in developing countries, where their impact is more severe. This article presents a participatory social diagnosis to analyze the determinants of health-related social practices associated with infectious diseases (malaria, tuberculosis, and leishmaniasis) among Indigenous and Afro-Colombian communities in Pueblo Rico, Colombia. We explore how social determinants, att…
Rapid and accurate identification and differentiation of Mycobacterium tuberculosis and non-tuberculous mycobacteria using PCR kits available in a high-burden setting
Infections caused by mycobacteria, including Mycobacterium tuberculosis complex (MTBC) and non-tuberculous mycobacteria (NTM), are a major public health issue worldwide. An accurate diagnosis of mycobacterial species is a challenge for surveillance and treatment, particularly in high-burden settings usually associated with low- and middle-income countries. In this study, we analyzed the clinical performance of two commercial PCR kits designed for…
Prevalence, drug resistance, and genotypic diversity of the RDRio subfamily of Mycobacterium tuberculosis in Ecuador
Introduction A major sublineage within the Mycobacterium tuberculosis (MTB) LAM family characterized by a new in-frame fusion gene Rv3346c/55c was discovered in Rio de Janeiro (Brazil) in 2007, called RD Rio , associated to drug resistance. The few studies about prevalence of MTB RD Rio strains in Latin America reported values ranging from 3% in Chile to 69.8% in Venezuela, although no information is available for countries like Ecuador. Methods …
A first insight into tuberculosis transmission at the border of Ecuador and Colombia
Objective: complex (MTBC) and to identify active transmission clusters of regional importance. Methods: We studied the potential transmission of TB between Colombia and Ecuador through the analysis of the population structure of MTBC lineages circulating in the Ecuadorian province of Esmeraldas at the border with Colombia. A total of 105 MTBC strains were characterized by 24-loci MIRU-VNTR and spoligotyping. Results: MTBC lineage 4 is only presen…
Coinfection of Sars-CoV-2 with other respiratory pathogens in outpatients from Ecuador
Worldwide, the COVID-19 pandemic caused by SARS-CoV-2 has enormously impacted healthcare systems, especially in low and middle-income countries. Coinfections with respiratory pathogens in COVID-19 patients may contribute to worse outcomes. This study identified the presence of 12 viral coinfections and pneumococcal carriers among individuals with SARS-CoV-2 infection in outpatient and community settings in Ecuador. From January 2020 to November 2…
Upholding academic freedom
OPINION article Front. Public Health, 07 September 2023Sec. Public Health Policy Volume 11 - 2023 | https://doi.org/10.3389/fpubh.2023.1259110
Quantification of early nonpharmaceutical interventions aimed at slowing transmission of Coronavirus Disease 2019 in the Navajo Nation and surrounding states (Arizona, Colorado, New Mexico, and Utah)
During an early period of the Coronavirus Disease 2019 (COVID-19) pandemic, the Navajo Nation, much like New York City, experienced a relatively high rate of disease transmission. Yet, between January and October 2020, it experienced only a single period of growth in new COVID-19 cases, which ended when cases peaked in May 2020. The daily number of new cases slowly decayed in the summer of 2020 until late September 2020. In contrast, the surround…
Diagnostic performance of four lateral flow immunoassays for Covid-19 antibodies in Peruvian population
Serological assays have been used in seroprevalence studies to inform the dynamics of COVID-19. Lateral flow immunoassay (LFIA) tests are a very practical technology to use for this objective; however, one of their challenges may be variable diagnostic performance. Given the numerous available LFIA tests, evaluation of their accuracy is critical before real-world implementation. We performed a retrospective diagnostic evaluation study to independ…
High rates of Sars-CoV-2 infection in funeral home workers in Ecuador
Aim The COVID-19 outbreak has already caused more than 6.5 million deaths, overwhelming health systems worldwide. The unusual demand for funeral home services could make these workers a potential risk group for occupational exposure to SARS-CoV-2 associated with corpses management for COVID-19 patients. Methodology This is a cross-sectional study aimed to describe the infection rate of SARS-CoV-2 in funeral home staff by testing them with RT-qPCR…
Epidemiological factors associated with HBV infection and uptake of testing in south west region of Cameroon
Hepatitis B infection affects millions of people globally, partly due to its high degree of transmissibility and asymptomatic nature. This study was aimed at identifying prevailing epidemiological factors associated with HBV infection and testing uptake in the South West region of Cameroon. This hospital-based case-control study enrolled HBV infected participants and “healthy” controls ≥18 years old. Venous blood collected from participants was u…
Pooling sputum for Xpert MTB/RIF and Xpert Ultra testing during the Covid-19 pandemic in Lao People’s Democratic Republic
The global Covid-19 pandemic has limited access to molecular TB diagnostics and National Programmes are struggling to maintain essential services. The pooling method (testing several samples together) could reduce the number of cartridges and staff time needed for TB diagnosis but has not been tested within the pandemic. We conducted two independent cross-sectional surveys. Pools composed of four sputum samples were tested using either Xpert-MTB/…
Sars-CoV-2 seroprevalence and risk factors among meat packing, produce processing, and farm workers
Meat packing, produce processing, and farm workers are known to have an elevated risk of COVID-19, but occupational risk factors in this population are unclear. We performed an observational cohort study of meat packing, produce processing, and farm workers in North Carolina in fall 2020. Blood, saliva, and nasal turbinate samples were collected to assess for SARS-CoV-2 seropositivity. Risk factors for SARS-CoV-2 seropositivity were investigated …
Sars-CoV-2 Viral Load Analysis at Low and High Altitude
SARS-CoV-2 has spread throughout the world, including remote areas such as those located at high altitudes. There is a debate about the role of hypobaric hypoxia on viral transmission and COVID-19 incidence. A descriptive cross-sectional analysis of SARS-CoV-2 infection and viral load among patients living at low (230 m) and high altitude (3800 m) in Ecuador was completed. Within these two communities, the total number of infected people at the t…
In response to ʺThe negative impact of ad hoc committees for ethical evaluation
No prominent works on this page.
In response to ʺThe negative impact of ad hoc committees for ethical evaluation
High rates of Sars-CoV-2 infection in funeral home workers in Ecuador
Aim The COVID-19 outbreak has already caused more than 6.5 million deaths, overwhelming health systems worldwide. The unusual demand for funeral home services could make these workers a potential risk group for occupational exposure to SARS-CoV-2 associated with corpses management for COVID-19 patients. Methodology This is a cross-sectional study aimed to describe the infection rate of SARS-CoV-2 in funeral home staff by testing them with RT-qPCR…
Epidemiological factors associated with HBV infection and uptake of testing in south west region of Cameroon
Hepatitis B infection affects millions of people globally, partly due to its high degree of transmissibility and asymptomatic nature. This study was aimed at identifying prevailing epidemiological factors associated with HBV infection and testing uptake in the South West region of Cameroon. This hospital-based case-control study enrolled HBV infected participants and “healthy” controls ≥18 years old. Venous blood collected from participants was u…
Pooling sputum for Xpert MTB/RIF and Xpert Ultra testing during the Covid-19 pandemic in Lao People’s Democratic Republic
The global Covid-19 pandemic has limited access to molecular TB diagnostics and National Programmes are struggling to maintain essential services. The pooling method (testing several samples together) could reduce the number of cartridges and staff time needed for TB diagnosis but has not been tested within the pandemic. We conducted two independent cross-sectional surveys. Pools composed of four sputum samples were tested using either Xpert-MTB/…
Sars-CoV-2 seroprevalence and risk factors among meat packing, produce processing, and farm workers
Meat packing, produce processing, and farm workers are known to have an elevated risk of COVID-19, but occupational risk factors in this population are unclear. We performed an observational cohort study of meat packing, produce processing, and farm workers in North Carolina in fall 2020. Blood, saliva, and nasal turbinate samples were collected to assess for SARS-CoV-2 seropositivity. Risk factors for SARS-CoV-2 seropositivity were investigated …
Sars-CoV-2 Viral Load Analysis at Low and High Altitude
SARS-CoV-2 has spread throughout the world, including remote areas such as those located at high altitudes. There is a debate about the role of hypobaric hypoxia on viral transmission and COVID-19 incidence. A descriptive cross-sectional analysis of SARS-CoV-2 infection and viral load among patients living at low (230 m) and high altitude (3800 m) in Ecuador was completed. Within these two communities, the total number of infected people at the t…
Coinfection of Sars-CoV-2 with other respiratory pathogens in outpatients from Ecuador
Worldwide, the COVID-19 pandemic caused by SARS-CoV-2 has enormously impacted healthcare systems, especially in low and middle-income countries. Coinfections with respiratory pathogens in COVID-19 patients may contribute to worse outcomes. This study identified the presence of 12 viral coinfections and pneumococcal carriers among individuals with SARS-CoV-2 infection in outpatient and community settings in Ecuador. From January 2020 to November 2…
Upholding academic freedom
OPINION article Front. Public Health, 07 September 2023Sec. Public Health Policy Volume 11 - 2023 | https://doi.org/10.3389/fpubh.2023.1259110
Quantification of early nonpharmaceutical interventions aimed at slowing transmission of Coronavirus Disease 2019 in the Navajo Nation and surrounding states (Arizona, Colorado, New Mexico, and Utah)
During an early period of the Coronavirus Disease 2019 (COVID-19) pandemic, the Navajo Nation, much like New York City, experienced a relatively high rate of disease transmission. Yet, between January and October 2020, it experienced only a single period of growth in new COVID-19 cases, which ended when cases peaked in May 2020. The daily number of new cases slowly decayed in the summer of 2020 until late September 2020. In contrast, the surround…
Diagnostic performance of four lateral flow immunoassays for Covid-19 antibodies in Peruvian population
Serological assays have been used in seroprevalence studies to inform the dynamics of COVID-19. Lateral flow immunoassay (LFIA) tests are a very practical technology to use for this objective; however, one of their challenges may be variable diagnostic performance. Given the numerous available LFIA tests, evaluation of their accuracy is critical before real-world implementation. We performed a retrospective diagnostic evaluation study to independ…
Rapid and accurate identification and differentiation of Mycobacterium tuberculosis and non-tuberculous mycobacteria using PCR kits available in a high-burden setting
Infections caused by mycobacteria, including Mycobacterium tuberculosis complex (MTBC) and non-tuberculous mycobacteria (NTM), are a major public health issue worldwide. An accurate diagnosis of mycobacterial species is a challenge for surveillance and treatment, particularly in high-burden settings usually associated with low- and middle-income countries. In this study, we analyzed the clinical performance of two commercial PCR kits designed for…
Prevalence, drug resistance, and genotypic diversity of the RDRio subfamily of Mycobacterium tuberculosis in Ecuador
Introduction A major sublineage within the Mycobacterium tuberculosis (MTB) LAM family characterized by a new in-frame fusion gene Rv3346c/55c was discovered in Rio de Janeiro (Brazil) in 2007, called RD Rio , associated to drug resistance. The few studies about prevalence of MTB RD Rio strains in Latin America reported values ranging from 3% in Chile to 69.8% in Venezuela, although no information is available for countries like Ecuador. Methods …
A first insight into tuberculosis transmission at the border of Ecuador and Colombia
Objective: complex (MTBC) and to identify active transmission clusters of regional importance. Methods: We studied the potential transmission of TB between Colombia and Ecuador through the analysis of the population structure of MTBC lineages circulating in the Ecuadorian province of Esmeraldas at the border with Colombia. A total of 105 MTBC strains were characterized by 24-loci MIRU-VNTR and spoligotyping. Results: MTBC lineage 4 is only presen…
Coinfections and superinfections in critically ill Covid-19 patients in Ecuador
Introduction The COVID-19 pandemic has deeply affected Latin America and Ecuador. Coinfections and superinfections increase the risk of morbidity and mortality in COVID-19 patients. This study examined co-infections and superinfections in critically ill COVID-19 patients admitted to the ICU of a tertiary hospital in Ecuador. Methods A cross-sectional study was conducted from February to August 2021, including patients with a confirmed SARS-CoV-2 …
Genomic surveillance of Sars-CoV-2 in the Andean Community (2020–2024)
Introduction: The COVID-19 pandemic has deeply affected Latin American countries, with countless COVID-19 cases and deaths. In countries like Peru, Colombia, Ecuador and Bolivia there was a collapse of the public health system, and the lack of testing capacity did not allow to control the spread of SARS-CoV-2 during the first year of the COVID-19 pandemic. After these dramatic beginnings, regional efforts focused on improving testing capacity and…
An intersectionality perspective on tuberculosis
Introduction: The Intersectionality approach to studying tuberculosis (TB) is a complex one. While historical data and indicators consistently suggest a positive correlation between social determinants, such as poverty, and TB mortality, the strength of this association varies across different regions and countries. Overcrowding and population density are also recognized as risk factors for TB transmission. Methods: In this study, we conducted a …
Population structure and antibiotic resistance profiles of Mycobacterium tuberculosis isolates from Ibadan, Nigeria (2019–2020)
Nigeria ranks as the sixth country globally and the first in Africa with the highest burden of tuberculosis (TB) infection. The emergence and spread of multidrug-resistant TB (MDR-TB) strains have posed significant challenges to effective disease management in the country. In this study, 55 Mycobacterium tuberculosis (MTB) isolates from patients attending a hospital in Ibadan city (Nigeria) were selected. MTB isolates were analyzed using PCR ampl…
Analyzing determinants of social practices in infectious diseases among Indigenous and Afro-Colombian communities
Infectious diseases pose major public health challenges worldwide, particularly in developing countries, where their impact is more severe. This article presents a participatory social diagnosis to analyze the determinants of health-related social practices associated with infectious diseases (malaria, tuberculosis, and leishmaniasis) among Indigenous and Afro-Colombian communities in Pueblo Rico, Colombia. We explore how social determinants, att…
Acceptability of tongue swabs for tuberculosis screening in migrant settings in northern Italy
Human migrations, driven by economic hardship, conflict, and climate change, complicate the global fight against tuberculosis (TB). New strategies are needed to improve the screening of migrants for active TB disease. Current sputum-based testing methods are logistically challenging in many settings. Alternative sampling with tongue swabs is designed to be easier than sputum collection and exhibits acceptable accuracy. This study characterized th…
Medicine (14 works) · Tuberculosis (8 works) · Tuberculosis Research and Epidemiology (7 works) · Virology (7 works) · Biology (6 works) · Internal Medicine (6 works) · Population (6 works) · Disease (5 works) · Immunology (5 works) · Pathology (5 works)