Roger Hernández
Biographic Data
| ID | 7038778 |
|---|---|
| NAME | Roger Hernández |
| GIVEN NAMES | Roger |
| FAMILY NAME | Hernández |
| SIGNATURE | HERNANDEZ R |
| AFFILIATIONS | Universidad Peruana Cayetano Heredia |
| ORCID | 0000-0002-1906-9599 |
| VERIFIED | Yes |
| TOTAL WORKS | 11 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 11 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2012 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
Caracteristicas clinicas y microbiológicas de pacientes pediátricos hospitalizados por neumonia neumococica antes y después de la introducción de las vacunas conjugadas neumocócicas
The clinical and microbiological characteristics of pneumococcal pneumonia in children hospitalized in Lima were analyzed, before and after the introduction of pneumococcal conjugate vaccines (PCV). We reviewed cases that occurred between 2006-2019, in the pre-PCV7 (2006-2008), post-PCV7 (2009-2011) and post-PCV13 (2016-2019) periods. Of 128 patients with positive cultures (92 blood and 36 pleural fluid), most were infants in the pre-PCV7 (77.1%)…
Detección de Streptococcus pneumoniae en líquidos estériles mediante una PCR en tiempo real (qPCR) en pacientes hospitalizados con sospecha de enfermedad neumocócica invasiva
The standard for diagnosing invasive pneumococcal disease (IPD) is to isolate pneumococcus in culture. However, the etiological agent cannot be identified in some patients, especially those who received empirical antibiotic therapy. This study aimed to detect pneumococcus in normally sterile fluids by qPCR in patients with suspected IPD hospitalized in Lima. qPCR had a detection limit of 1.2 x 101 genome copies/uL. Of the 71 clinical samples (51 …
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019
BACKGROUND: Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infection in young children. We previously estimated that in 2015, 33·1 million episodes of RSV-associated acute lower respiratory infection occurred in children aged 0-60 months, resulting in a total of 118 200 deaths worldwide. Since then, several community surveillance studies have been done to obtain a more precise estimation of RSV associated co…
Incidencia y factores de riesgo de infecciones del torrente sanguíneo asociadas a catéter central
Central line catheter-related bloodstream infections (CLABSI) burdens great morbidity, mortality and unnecessary hospital expenses. Studies related to its incidence and epidemiological and clinical profile among neonates in Peru are scarce, not being clear it's actual impact. A prospective cohort study was conducted in a neonatal intensive care unit (ICU) of a public hospital in Lima, Peru between 2017-2018. 167 patients were included (52,7% male…
Resistencia antibiótica y distribución de serotipos en cepas neumocócicas invasivas en adultos hospitalizados en Lima, Perú
Pneumococcus is an important pathogen in adults, particularly in older adults, owing to its high mortality rate
Características epidemiológicas, clínicas y bacteriológicas de meningitis neumocócica en pacientes pediátricos de Lima, Perú
Pneumococcal meningitis continues to be a lethal disease, especially in children less than 2 years of age. Since almost two third of lethal cases lead to death within the first 48 hours, prompt diagnosis and management is critical, as well as assurance of immunization with pneumococcal vaccine
Frecuencia de hepatitis A en niños y adolescentes de cinco ciudades del Perú
In order to determine the frequency of hepatitis A in children and adolescents in the cities of Lima, Arequipa, Piura, Cajamarca and Iquitos, a descriptive cross-sectional study which measured serum anti-hepatitis A antibodies from 1,721 children and adolescents aged 1-15 years was performed. The overall frequency of positive serology was 50.5% (95% CI: 48.1 to 52.9), with lower rates for Lima at 37.4% (95% CI: 35.1 to 39.8) and higher rates for …
Infecciones del sistema nervioso central por enterovirus en niños atendidos en un hospital de Lima, Perú
Objectives. To determine the frequency and clinical features of central nervous system infections caused by enterovirus in children treated at the Hospital Nacional Cayetano Heredia in Lima, Peru. Materials and methods. A prospective, descriptive study was performed from April 2008 to March 2010. Patients aged 1 month – 14 years with clinical diagnosis of encephalitis or aseptic meningitis were included. We investigated the presence of enteroviru…
Resistencia antibiótica de Streptococcus pneumoniae en portadores nasofaríngeos sanos de siete regiones del Perú
High levels of resistance found to penicillin, co-trimoxasole and macrolides in isolated pneumococcus strains of healthy carriers in all studied regions, and their association to a previous use of antibiotics, represent a significant public health problem in our country. This emphasizes the need to implement nationwide strategies to reduce the irrational use of antibiotics, especially among children. It is necessary to complement data of resistan…
Serotipos de neumococo en niños portadores antes de la vacunación antineumocócica en el Perú
Objectives. To determine the carriage rate and serotype distribution of Streptococcus pneumoniae in the nasopharynx of healthy children younger than 2 years prior to the universal use of the pneumococcal conjugate vaccines in Peru. Materials and methods. Between 2007 and 2009 we collected nasopharyngeal swab samples from 2,123 healthy children aged 2 to 24 months in the vaccination and healthy children consultation offices of pediatric hospitals …
Serotipos de neumococo en niños portadores antes de la vacunación antineumocócica en el Perú
The distribution of vaccine serotypes in the analyzed strains was of 50% for the serotypes present in the seven-valent vaccine, 50.2% for the serotypes present in the ten-valent vaccine and 57.2% for those present in the thirteen-valent vaccine
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Serotipos de neumococo en niños portadores antes de la vacunación antineumocócica en el Perú
The distribution of vaccine serotypes in the analyzed strains was of 50% for the serotypes present in the seven-valent vaccine, 50.2% for the serotypes present in the ten-valent vaccine and 57.2% for those present in the thirteen-valent vaccine
Infecciones del sistema nervioso central por enterovirus en niños atendidos en un hospital de Lima, Perú
Objectives. To determine the frequency and clinical features of central nervous system infections caused by enterovirus in children treated at the Hospital Nacional Cayetano Heredia in Lima, Peru. Materials and methods. A prospective, descriptive study was performed from April 2008 to March 2010. Patients aged 1 month – 14 years with clinical diagnosis of encephalitis or aseptic meningitis were included. We investigated the presence of enteroviru…
Resistencia antibiótica de Streptococcus pneumoniae en portadores nasofaríngeos sanos de siete regiones del Perú
High levels of resistance found to penicillin, co-trimoxasole and macrolides in isolated pneumococcus strains of healthy carriers in all studied regions, and their association to a previous use of antibiotics, represent a significant public health problem in our country. This emphasizes the need to implement nationwide strategies to reduce the irrational use of antibiotics, especially among children. It is necessary to complement data of resistan…
Serotipos de neumococo en niños portadores antes de la vacunación antineumocócica en el Perú
Objectives. To determine the carriage rate and serotype distribution of Streptococcus pneumoniae in the nasopharynx of healthy children younger than 2 years prior to the universal use of the pneumococcal conjugate vaccines in Peru. Materials and methods. Between 2007 and 2009 we collected nasopharyngeal swab samples from 2,123 healthy children aged 2 to 24 months in the vaccination and healthy children consultation offices of pediatric hospitals …
Frecuencia de hepatitis A en niños y adolescentes de cinco ciudades del Perú
In order to determine the frequency of hepatitis A in children and adolescents in the cities of Lima, Arequipa, Piura, Cajamarca and Iquitos, a descriptive cross-sectional study which measured serum anti-hepatitis A antibodies from 1,721 children and adolescents aged 1-15 years was performed. The overall frequency of positive serology was 50.5% (95% CI: 48.1 to 52.9), with lower rates for Lima at 37.4% (95% CI: 35.1 to 39.8) and higher rates for …
Características epidemiológicas, clínicas y bacteriológicas de meningitis neumocócica en pacientes pediátricos de Lima, Perú
Pneumococcal meningitis continues to be a lethal disease, especially in children less than 2 years of age. Since almost two third of lethal cases lead to death within the first 48 hours, prompt diagnosis and management is critical, as well as assurance of immunization with pneumococcal vaccine
Resistencia antibiótica y distribución de serotipos en cepas neumocócicas invasivas en adultos hospitalizados en Lima, Perú
Pneumococcus is an important pathogen in adults, particularly in older adults, owing to its high mortality rate
Incidencia y factores de riesgo de infecciones del torrente sanguíneo asociadas a catéter central
Central line catheter-related bloodstream infections (CLABSI) burdens great morbidity, mortality and unnecessary hospital expenses. Studies related to its incidence and epidemiological and clinical profile among neonates in Peru are scarce, not being clear it's actual impact. A prospective cohort study was conducted in a neonatal intensive care unit (ICU) of a public hospital in Lima, Peru between 2017-2018. 167 patients were included (52,7% male…
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019
BACKGROUND: Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infection in young children. We previously estimated that in 2015, 33·1 million episodes of RSV-associated acute lower respiratory infection occurred in children aged 0-60 months, resulting in a total of 118 200 deaths worldwide. Since then, several community surveillance studies have been done to obtain a more precise estimation of RSV associated co…
Caracteristicas clinicas y microbiológicas de pacientes pediátricos hospitalizados por neumonia neumococica antes y después de la introducción de las vacunas conjugadas neumocócicas
The clinical and microbiological characteristics of pneumococcal pneumonia in children hospitalized in Lima were analyzed, before and after the introduction of pneumococcal conjugate vaccines (PCV). We reviewed cases that occurred between 2006-2019, in the pre-PCV7 (2006-2008), post-PCV7 (2009-2011) and post-PCV13 (2016-2019) periods. Of 128 patients with positive cultures (92 blood and 36 pleural fluid), most were infants in the pre-PCV7 (77.1%)…
Detección de Streptococcus pneumoniae en líquidos estériles mediante una PCR en tiempo real (qPCR) en pacientes hospitalizados con sospecha de enfermedad neumocócica invasiva
The standard for diagnosing invasive pneumococcal disease (IPD) is to isolate pneumococcus in culture. However, the etiological agent cannot be identified in some patients, especially those who received empirical antibiotic therapy. This study aimed to detect pneumococcus in normally sterile fluids by qPCR in patients with suspected IPD hospitalized in Lima. qPCR had a detection limit of 1.2 x 101 genome copies/uL. Of the 71 clinical samples (51 …
Medicine (10 works) · Pneumonia and Respiratory Infections (7 works) · Respiratory viral infections research (7 works) · Biology (5 works) · Bacterial Infections and Vaccines (4 works) · Microbiology (4 works) · Pediatrics (4 works) · Antibiotics (3 works) · Streptococcus pneumoniae (3 works) · Epidemiology (2 works)