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Kathy J Jenkins

Biographic Data

ID7056694
NAMEKathy J Jenkins
GIVEN NAMESKathy J
FAMILY NAMEJenkins
SIGNATUREJENKINS K J
AFFILIATIONSBoston Children's Hospital
ORCID0000-0002-8702-988X
VERIFIEDYes
TOTAL WORKS16
TOTAL CITATIONS0
WORKS AS AUTHOR16
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2018
LATEST PUBLICATION YEAR2024
H-INDEX0
  • Prediction of low birth weight from fetal ultrasound and clinical characteristics

    Open Access•Sergio Sanchez-Martinez, Pablo Miki Marti-Castellote et al.•ARTICLE•BMJ Global Health•2024

    Introduction Adverse perinatal outcomes (APO) pose a significant global challenge, particularly in low- and middle-income countries (LMICs). This study aims to analyse two cohorts of high-risk pregnant women for APO to comprehend risk factors and improve prediction accuracy. Methods We considered an LMIC and a high-income country (HIC) population to derive XGBoost classifiers to predict low birth weight (LBW) from a comprehensive set of maternal …

  • Exploring Stress and Coping in Caregivers of Children with Pulmonary Vein Stenosis

    Open Access•Mark Fuller, Mark G Fuller et al.•ARTICLE•Children•2024

    (1) Background: This mixed-method study aims to identify and describe factors associated with acute and long-term parenting stressors and coping strategies in caregivers of children with intraluminal pulmonary vein stenosis (PVS). (2) Methods: Parents of children with severe PVS were recruited from a large quaternary hospital to complete a survey that included demographics, the Pediatric Inventory for Parents (PIP), and the Coping Health Inventor…

  • Recommendations for developing effective and safe paediatric and congenital heart disease services in low-income and middle-income countries

    Open Access•Babar S Hasan, Babar Hasan et al.•ARTICLE•BMJ Global Health•2023

    The global burden of paediatric and congenital heart disease (PCHD) is substantial. We propose a novel public health framework with recommendations for developing effective and safe PCHD services in low-income and middle-income countries (LMICs). This framework was created by the Global Initiative for Children’s Surgery Cardiac Surgery working group in collaboration with a group of international rexperts in providing paediatric and congenital car…

  • Pleuropulmonary MDCT Findings

    Open Access•Abbey J Winant, Sara O Vargas et al.•ARTICLE•Children•2022

    Purpose: To retrospectively compare the pleuropulmonary MDCT findings in children with pulmonary vein stenosis (PVS) and prematurity-related lung disease (PLD). Materials and Methods: All consecutive infants and young children (≤18 years old) who underwent thoracic MDCT studies from July 2004 to November 2021 were categorized into two groups—children with PVS (Group 1) and children with PLD without PVS (Group 2). Two pediatric radiologists indepe…

  • Lung and Pleural Findings of Children with Pulmonary Vein Stenosis with and without Aspiration

    Open Access•Abbey J Winant, Ryan Callahan et al.•ARTICLE•Children•2022

    Purpose: To retrospectively compare the lung and pleural findings in children with pulmonary vein stenosis (PVS) with and without aspiration on multidetector computed tomography (MDCT). Materials and Methods: All consecutive children (≤18 years old) with PVS who underwent thoracic MDCT studies from August 2004 to December 2021 were categorized into two groups: children with PVS with aspiration (Group 1) and children with PVS without aspiration (G…

  • Progress in Pulmonary Vein Stenosis

    Open Access•Kathy J Jenkins, Jeffrey R Fineman•ARTICLE•Children•2022

    Pulmonary vein stenosis (PVS) is a rare and poorly understood condition that can be classified as primary, acquired, status-post surgical repair of PVS, and/or associated with developmental lung disease. Immunohistochemical studies demonstrate that obstruction of the large (extrapulmonary) pulmonary veins is associated with the neointimal proliferation of myofibroblasts. This rare disorder is likely multifactorial with a spectrum of pathobiology.…

  • Patient and Family-Centered Care for Pediatric Intraluminal Pulmonary Vein Stenosis

    Open Access•Christina M Ireland, Ryan Callahan et al.•ARTICLE•Children•2021

    A nurse practitioner’s experience in managing children with intraluminal pulmonary vein stenosis. A case study of a 3-year-old patient with multi–vessel intraluminal pulmonary vein stenosis

  • Outcomes in Establishing Individual Vessel Patency for Pediatric Pulmonary Vein Stenosis

    Open Access•Ryan Callahan, Kimberlee Gauvreau et al.•ARTICLE•Children•2021

    The purpose of this study was to determine what patient and pulmonary vein characteristics at the diagnosis of intraluminal pulmonary vein stenosis (PVS) are predictive of individual vein outcomes. A retrospective, single-center, cohort sub-analysis of individual pulmonary veins of patients enrolled in the clinical trial NCT00891527 using imatinib mesylate +/- bevacizumab as adjunct therapy for the treatment of multi-vessel pediatric PVS between …

  • Pulmonary Vein Stenosis

    Open Access•Jennifer Schramm, Sivakumar Sivalingam et al.•ARTICLE•Children•2021

    Pulmonary vein stenosis (PVS) is a rare, but high mortality and resource intensive disease caused by mechanical obstruction or intraluminal myofibroproliferation, which can be post-surgical or idiopathic. There are increasing options for management including medications, cardiac catheterization procedures, and surgery. We queried the International Quality Improvement Collaborative for Congenital Heart Disease (IQIC) database for cases of PVS and …

  • Clinical Syndromic Phenotypes and the Potential Role of Genetics in Pulmonary Vein Stenosis

    Open Access•Abbas H Zaidi, Jessica M Yamada et al.•ARTICLE•Children•2021

    Pulmonary vein stenosis (PVS) is a rare, frequently lethal disease with heterogeneous phenotypes and an unclear etiology. Limited studies have reported associations between PVS and congenital heart disease (CHD), chronic lung disease (CLD), and/or prematurity; however, to date, there have been no studies that report detailed clinical syndromic phenotypes and the potential role of genetics in PVS. An existing registry of multivessel PVS patients s…

  • Aspiration Is Associated with Poor Treatment Response in Pediatric Pulmonary Vein Stenosis

    Open Access•Maria Niccum, Ryan Callahan et al.•ARTICLE•Children•2021

    Intraluminal pulmonary vein stenosis is a disease with significant morbidity and mortality, though recent progress has been made using multimodal therapy with antiproliferative agents. The aim of this study was to evaluate the association between aspiration and poor treatment response in patients with intraluminal pulmonary vein stenosis. A retrospective, single-center cohort analysis was performed of patients treated with a combination of imatin…

  • Secondary Pulmonary Vein Stenosis Due to Total Anomalous Pulmonary Venous Connection Repair in Children

    Open Access•Edward Y Lee, Sara O Vargas et al.•ARTICLE•Children•2021

    Our study characterizes the extravascular thoracic MDCT angiography findings in secondary pediatric PVS due to TAPVC repair. In the lungs and pleura, ground-glass opacity, interlobular septal thickening, and pleural thickening are common findings. Importantly, the presence of a mildly heterogeneously enhancing, non-calcified mediastinal soft tissue mass in the distribution of the PVS is a novel characteristic thoracic MDCT angiography finding see…

  • Extravascular MDCT Findings of Pulmonary Vein Stenosis in Children with Cardiac Septal Defect

    Open Access•Edward Y Lee, Ryan Callahan et al.•ARTICLE•Children•2021

    Purpose : To retrospectively investigate the extravascular thoracic MDCT angiography findings of pulmonary vein stenosis (PVS) in children with a cardiac septal defect. Materials and Methods: Pediatric patients (age ≤ 18 years) with cardiac septal defect and PVS, confirmed by echocardiogram and/or conventional angiography, who underwent thoracic MDCT angiography studies from April 2009 to April 2021 were included. Two pediatric radiologists indep…

  • The Role of Elevated Wall Shear Stress in Progression of Pulmonary Vein Stenosis

    Open Access•Peter E Hammer, Kerry McEnaney et al.•ARTICLE•Children•2021

    Pulmonary vein stenosis is a serious condition characterized by restriction or blockage due to fibrotic tissue ingrowth that develops in the pulmonary veins of infants or children. It is often progressive and can lead to severe pulmonary hypertension and death. Efforts to halt or reverse disease progression include surgery and catheter-based balloon dilation and stent implantation. Its cause and mechanism of progression are unknown. In this pilot…

  • Longer Exposure to Left-to-Right Shunts Is a Risk Factor for Pulmonary Vein Stenosis in Patients with Trisomy 21

    Open Access•Connie Choi, Kimberlee Gauvreau et al.•ARTICLE•Children•2021

    We conducted a study to determine whether patients born with Trisomy 21 and left-to-right shunts who develop pulmonary vein stenosis (PVS) have a longer exposure to shunt physiology compared to those who do not develop PVS. We included patients seen at Boston Children's Hospital between 15 August 2006 and 31 August 2017 born with Trisomy 21 and left-to-right shunts who developed PVS within 24 months of age. We conducted a retrospective 3:1 matche…

  • Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017

    Open Access•Gregory A Roth, D Abate et al.•ARTICLE•The Lancet•2018

    BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly available data and improved methods. GBD …

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  • Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017

    Open Access•Gregory A Roth, D Abate et al.•ARTICLE•The Lancet•2018

    BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly available data and improved methods. GBD …

  • Patient and Family-Centered Care for Pediatric Intraluminal Pulmonary Vein Stenosis

    Open Access•Christina M Ireland, Ryan Callahan et al.•ARTICLE•Children•2021

    A nurse practitioner’s experience in managing children with intraluminal pulmonary vein stenosis. A case study of a 3-year-old patient with multi–vessel intraluminal pulmonary vein stenosis

  • Outcomes in Establishing Individual Vessel Patency for Pediatric Pulmonary Vein Stenosis

    Open Access•Ryan Callahan, Kimberlee Gauvreau et al.•ARTICLE•Children•2021

    The purpose of this study was to determine what patient and pulmonary vein characteristics at the diagnosis of intraluminal pulmonary vein stenosis (PVS) are predictive of individual vein outcomes. A retrospective, single-center, cohort sub-analysis of individual pulmonary veins of patients enrolled in the clinical trial NCT00891527 using imatinib mesylate +/- bevacizumab as adjunct therapy for the treatment of multi-vessel pediatric PVS between …

  • Pulmonary Vein Stenosis

    Open Access•Jennifer Schramm, Sivakumar Sivalingam et al.•ARTICLE•Children•2021

    Pulmonary vein stenosis (PVS) is a rare, but high mortality and resource intensive disease caused by mechanical obstruction or intraluminal myofibroproliferation, which can be post-surgical or idiopathic. There are increasing options for management including medications, cardiac catheterization procedures, and surgery. We queried the International Quality Improvement Collaborative for Congenital Heart Disease (IQIC) database for cases of PVS and …

  • Clinical Syndromic Phenotypes and the Potential Role of Genetics in Pulmonary Vein Stenosis

    Open Access•Abbas H Zaidi, Jessica M Yamada et al.•ARTICLE•Children•2021

    Pulmonary vein stenosis (PVS) is a rare, frequently lethal disease with heterogeneous phenotypes and an unclear etiology. Limited studies have reported associations between PVS and congenital heart disease (CHD), chronic lung disease (CLD), and/or prematurity; however, to date, there have been no studies that report detailed clinical syndromic phenotypes and the potential role of genetics in PVS. An existing registry of multivessel PVS patients s…

  • Aspiration Is Associated with Poor Treatment Response in Pediatric Pulmonary Vein Stenosis

    Open Access•Maria Niccum, Ryan Callahan et al.•ARTICLE•Children•2021

    Intraluminal pulmonary vein stenosis is a disease with significant morbidity and mortality, though recent progress has been made using multimodal therapy with antiproliferative agents. The aim of this study was to evaluate the association between aspiration and poor treatment response in patients with intraluminal pulmonary vein stenosis. A retrospective, single-center cohort analysis was performed of patients treated with a combination of imatin…

  • Secondary Pulmonary Vein Stenosis Due to Total Anomalous Pulmonary Venous Connection Repair in Children

    Open Access•Edward Y Lee, Sara O Vargas et al.•ARTICLE•Children•2021

    Our study characterizes the extravascular thoracic MDCT angiography findings in secondary pediatric PVS due to TAPVC repair. In the lungs and pleura, ground-glass opacity, interlobular septal thickening, and pleural thickening are common findings. Importantly, the presence of a mildly heterogeneously enhancing, non-calcified mediastinal soft tissue mass in the distribution of the PVS is a novel characteristic thoracic MDCT angiography finding see…

  • Extravascular MDCT Findings of Pulmonary Vein Stenosis in Children with Cardiac Septal Defect

    Open Access•Edward Y Lee, Ryan Callahan et al.•ARTICLE•Children•2021

    Purpose : To retrospectively investigate the extravascular thoracic MDCT angiography findings of pulmonary vein stenosis (PVS) in children with a cardiac septal defect. Materials and Methods: Pediatric patients (age ≤ 18 years) with cardiac septal defect and PVS, confirmed by echocardiogram and/or conventional angiography, who underwent thoracic MDCT angiography studies from April 2009 to April 2021 were included. Two pediatric radiologists indep…

  • The Role of Elevated Wall Shear Stress in Progression of Pulmonary Vein Stenosis

    Open Access•Peter E Hammer, Kerry McEnaney et al.•ARTICLE•Children•2021

    Pulmonary vein stenosis is a serious condition characterized by restriction or blockage due to fibrotic tissue ingrowth that develops in the pulmonary veins of infants or children. It is often progressive and can lead to severe pulmonary hypertension and death. Efforts to halt or reverse disease progression include surgery and catheter-based balloon dilation and stent implantation. Its cause and mechanism of progression are unknown. In this pilot…

  • Longer Exposure to Left-to-Right Shunts Is a Risk Factor for Pulmonary Vein Stenosis in Patients with Trisomy 21

    Open Access•Connie Choi, Kimberlee Gauvreau et al.•ARTICLE•Children•2021

    We conducted a study to determine whether patients born with Trisomy 21 and left-to-right shunts who develop pulmonary vein stenosis (PVS) have a longer exposure to shunt physiology compared to those who do not develop PVS. We included patients seen at Boston Children's Hospital between 15 August 2006 and 31 August 2017 born with Trisomy 21 and left-to-right shunts who developed PVS within 24 months of age. We conducted a retrospective 3:1 matche…

  • Pleuropulmonary MDCT Findings

    Open Access•Abbey J Winant, Sara O Vargas et al.•ARTICLE•Children•2022

    Purpose: To retrospectively compare the pleuropulmonary MDCT findings in children with pulmonary vein stenosis (PVS) and prematurity-related lung disease (PLD). Materials and Methods: All consecutive infants and young children (≤18 years old) who underwent thoracic MDCT studies from July 2004 to November 2021 were categorized into two groups—children with PVS (Group 1) and children with PLD without PVS (Group 2). Two pediatric radiologists indepe…

  • Lung and Pleural Findings of Children with Pulmonary Vein Stenosis with and without Aspiration

    Open Access•Abbey J Winant, Ryan Callahan et al.•ARTICLE•Children•2022

    Purpose: To retrospectively compare the lung and pleural findings in children with pulmonary vein stenosis (PVS) with and without aspiration on multidetector computed tomography (MDCT). Materials and Methods: All consecutive children (≤18 years old) with PVS who underwent thoracic MDCT studies from August 2004 to December 2021 were categorized into two groups: children with PVS with aspiration (Group 1) and children with PVS without aspiration (G…

  • Progress in Pulmonary Vein Stenosis

    Open Access•Kathy J Jenkins, Jeffrey R Fineman•ARTICLE•Children•2022

    Pulmonary vein stenosis (PVS) is a rare and poorly understood condition that can be classified as primary, acquired, status-post surgical repair of PVS, and/or associated with developmental lung disease. Immunohistochemical studies demonstrate that obstruction of the large (extrapulmonary) pulmonary veins is associated with the neointimal proliferation of myofibroblasts. This rare disorder is likely multifactorial with a spectrum of pathobiology.…

  • Recommendations for developing effective and safe paediatric and congenital heart disease services in low-income and middle-income countries

    Open Access•Babar S Hasan, Babar Hasan et al.•ARTICLE•BMJ Global Health•2023

    The global burden of paediatric and congenital heart disease (PCHD) is substantial. We propose a novel public health framework with recommendations for developing effective and safe PCHD services in low-income and middle-income countries (LMICs). This framework was created by the Global Initiative for Children’s Surgery Cardiac Surgery working group in collaboration with a group of international rexperts in providing paediatric and congenital car…

  • Prediction of low birth weight from fetal ultrasound and clinical characteristics

    Open Access•Sergio Sanchez-Martinez, Pablo Miki Marti-Castellote et al.•ARTICLE•BMJ Global Health•2024

    Introduction Adverse perinatal outcomes (APO) pose a significant global challenge, particularly in low- and middle-income countries (LMICs). This study aims to analyse two cohorts of high-risk pregnant women for APO to comprehend risk factors and improve prediction accuracy. Methods We considered an LMIC and a high-income country (HIC) population to derive XGBoost classifiers to predict low birth weight (LBW) from a comprehensive set of maternal …

  • Exploring Stress and Coping in Caregivers of Children with Pulmonary Vein Stenosis

    Open Access•Mark Fuller, Mark G Fuller et al.•ARTICLE•Children•2024

    (1) Background: This mixed-method study aims to identify and describe factors associated with acute and long-term parenting stressors and coping strategies in caregivers of children with intraluminal pulmonary vein stenosis (PVS). (2) Methods: Parents of children with severe PVS were recruited from a large quaternary hospital to complete a survey that included demographics, the Pediatric Inventory for Parents (PIP), and the Coping Health Inventor…

Medicine (16 works) · Congenital Heart Disease Studies (12 works) · Internal Medicine (11 works) · Stenosis (11 works) · Pulmonary vein (9 works) · Cardiology (8 works) · Pulmonary vein stenosis (8 works) · Radiology (7 works) · Lung (6 works) · Surgery (5 works)

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