Zhihong Ji
Dados Biográficos
| ID | 7270984 |
|---|---|
| NOME | Zhihong Ji |
| PRENOMES | Zhihong |
| SOBRENOME | Ji |
| ASSINATURA | JI Z |
| AFILIAÇÕES | Xinjiang Entry-Exit Inspection and Quarantine Bureau |
| VERIFICADO | Não |
| TOTAL DE OBRAS | 5 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 5 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2022 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 0 |
Discrimination of the significance of astragalosides in Astragalus radix based on the in vivo exposure levels and pharmacokinetic characteristics of prototype saponins and their metabolites
Exploring the optimal timing of HanChuan Zupa Granule for asthma treatment using a comprehensive research approach of “Disease circadian rhythm-drug target prediction-drug efficacy validation”
1Network pharmacological analyses showed that among the immune response-related pathways, the IL-17 signalling pathway had the highest aggregation and was associated with Th2 cells in asthma pathogenesis. 2In biological effect experiments, HCZP of all time subgroups could delay the progression of asthma pathology to a certain extent, increased FVC, FEV75, PEF, MMEF, IC to different degrees, and down-regulated IgE and Th2 characteristic cytokine e…
A novel mechanism for regulating lung immune homeostasis
ZKMG can reduce the degree of lung tissue injury in ALI by inhibiting NLRP3/Caspase-1/GSDMD signaling pathway and restoring the IL-17A/IL-10 cytokine balance, and its protective mechanism may be related to the regulation of lung immune homeostasis. It will provide a new strategy for studying the regulation of lung immune homeostasis
A novel therapeutic approach for IPF
By inhibiting proliferation, enhancing phagocytosis, inhibiting the formation of Bcl-2 complex, and inhibiting the high expression of MYD88-dependent TLR4 signaling pathway, ZKMG can regulate the balance of AMs "autophagy - apoptosis" in the alveolitis stage to retard the fibrosis process partly. With a comprehensive strategy of "target prediction - experimental verification", we have demonstrated that inhibiting the apoptosis and promoting autop…
Application of network composite module analysis and verification to explore the bidirectional immunomodulatory effect of Zukamu granules on Th1 / Th2 cytokines in lung injury
The network composite module analysis and verification method is an exploration to study the immune regulation mechanism of TCM by combining the network module prediction analysis with animal experiments, which provides a reference for subsequent research
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A novel therapeutic approach for IPF
By inhibiting proliferation, enhancing phagocytosis, inhibiting the formation of Bcl-2 complex, and inhibiting the high expression of MYD88-dependent TLR4 signaling pathway, ZKMG can regulate the balance of AMs "autophagy - apoptosis" in the alveolitis stage to retard the fibrosis process partly. With a comprehensive strategy of "target prediction - experimental verification", we have demonstrated that inhibiting the apoptosis and promoting autop…
Application of network composite module analysis and verification to explore the bidirectional immunomodulatory effect of Zukamu granules on Th1 / Th2 cytokines in lung injury
The network composite module analysis and verification method is an exploration to study the immune regulation mechanism of TCM by combining the network module prediction analysis with animal experiments, which provides a reference for subsequent research
A novel mechanism for regulating lung immune homeostasis
ZKMG can reduce the degree of lung tissue injury in ALI by inhibiting NLRP3/Caspase-1/GSDMD signaling pathway and restoring the IL-17A/IL-10 cytokine balance, and its protective mechanism may be related to the regulation of lung immune homeostasis. It will provide a new strategy for studying the regulation of lung immune homeostasis
Exploring the optimal timing of HanChuan Zupa Granule for asthma treatment using a comprehensive research approach of “Disease circadian rhythm-drug target prediction-drug efficacy validation”
1Network pharmacological analyses showed that among the immune response-related pathways, the IL-17 signalling pathway had the highest aggregation and was associated with Th2 cells in asthma pathogenesis. 2In biological effect experiments, HCZP of all time subgroups could delay the progression of asthma pathology to a certain extent, increased FVC, FEV75, PEF, MMEF, IC to different degrees, and down-regulated IgE and Th2 characteristic cytokine e…
Discrimination of the significance of astragalosides in Astragalus radix based on the in vivo exposure levels and pharmacokinetic characteristics of prototype saponins and their metabolites
Medicine (4 obras) · Pharmacology (4 obras) · Immunology (3 obras) · Biology (2 obras) · Cell Biology (2 obras) · Immune system (2 obras) · Inflammasome and immune disorders (2 obras) · Inflammation (2 obras) · Internal Medicine (2 obras) · Signal transduction (2 obras)