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Le Guo

Biographic Data

ID7277907
NAMELe Guo
FAMILY NAMELe Guo
SIGNATURELE GUO
AFFILIATIONSZhejiang Chinese Medical University
ORCID0000-0002-9882-8230
VERIFIEDYes
TOTAL WORKS6
TOTAL CITATIONS0
WORKS AS AUTHOR6
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2022
LATEST PUBLICATION YEAR2026
H-INDEX0
  • Current status and progress of validation studies on the Icope scale

    Open Access•Yuan Zhao, Y Q Zhao et al.•ARTICLE•Frontiers in Public Health•2026

    Background: With the rapid global population aging, systematically and early identifying and managing functional decline in older adults has become a core challenge in public health. The Integrated Care for Older People (ICOPE) framework and its screening tool, proposed by the World Health Organization (WHO), aim to prevent disability by assessing intrinsic capacity. However, there is a lack of systematic review of the implementation strategies, …

  • Sensory impairment and risk of incident depression in older adults

    Open Access•Lin Guo, Le Guo et al.•ARTICLE•Frontiers in Public Health•2026

    Background Evidence linking sensory impairment to depression is predominantly Western. We quantified longitudinal associations of single and dual sensory impairment (DSI) with incident depression using harmonized data from six countries. Methods We analyzed 72,177 older adults (aged ≥50) from HRS (USA), ELSA (UK), SHARE (Europe), CHARLS (China), KLOSA (South Korea), and MHAS (Mexico). Participants free of depression at baseline (2010–2015) were f…

  • Development and validation of a scale of healthy psychological effects of physical exercise among Chinese college students from a multidimensional mental health perspective

    Open Access•Feiyang Liu, Zhengguang Zhu et al.•ARTICLE•Frontiers in Public Health•2026

    Background Physical exercise promotes mental health among college students, but existing studies often assess general mental health or limited psychological indicators, making it difficult to capture comprehensive healthy psychological effects after exercise. This study aimed to develop and validate the Healthy Psychological Effects of Physical Exercise Scale for College Students . Methods An initial scale was developed through theoretical analys…

  • The relationship between disability and quality of life among older adults

    Open Access•Jing Zhu, Zhiqiang Feng et al.•ARTICLE•Frontiers in Public Health•2026

    Background The acceleration of population aging, especially in China, has led to a rapid growth in the number of older adults living with disabilities, posing significant challenges to public health and quality of life (QoL). From the perspective of the biopsychosocial framework, the adverse impact of disability (a biological and functional factor) on QoL has been well documented. However, the underlying mechanisms linking disability to QoL withi…

  • Green tea-derived theabrownin suppresses human non-small cell lung carcinoma in xenograft model through activation of not only p53 signaling but also Mapk/JNK signaling pathway

    Open Access•Xiujuan Xiao, Le Guo et al.•ARTICLE•Journal of Ethnopharmacology•2022

  • Tanshinol suppresses osteosarcoma by specifically inducing apoptosis of U2-OS cells through p53-mediated mechanism

    Open Access•Shihui Yu, Le Guo et al.•ARTICLE•Journal of Ethnopharmacology•2022

No prominent works on this page.

  • Green tea-derived theabrownin suppresses human non-small cell lung carcinoma in xenograft model through activation of not only p53 signaling but also Mapk/JNK signaling pathway

    Open Access•Xiujuan Xiao, Le Guo et al.•ARTICLE•Journal of Ethnopharmacology•2022

  • Tanshinol suppresses osteosarcoma by specifically inducing apoptosis of U2-OS cells through p53-mediated mechanism

    Open Access•Shihui Yu, Le Guo et al.•ARTICLE•Journal of Ethnopharmacology•2022

  • Current status and progress of validation studies on the Icope scale

    Open Access•Yuan Zhao, Y Q Zhao et al.•ARTICLE•Frontiers in Public Health•2026

    Background: With the rapid global population aging, systematically and early identifying and managing functional decline in older adults has become a core challenge in public health. The Integrated Care for Older People (ICOPE) framework and its screening tool, proposed by the World Health Organization (WHO), aim to prevent disability by assessing intrinsic capacity. However, there is a lack of systematic review of the implementation strategies, …

  • Sensory impairment and risk of incident depression in older adults

    Open Access•Lin Guo, Le Guo et al.•ARTICLE•Frontiers in Public Health•2026

    Background Evidence linking sensory impairment to depression is predominantly Western. We quantified longitudinal associations of single and dual sensory impairment (DSI) with incident depression using harmonized data from six countries. Methods We analyzed 72,177 older adults (aged ≥50) from HRS (USA), ELSA (UK), SHARE (Europe), CHARLS (China), KLOSA (South Korea), and MHAS (Mexico). Participants free of depression at baseline (2010–2015) were f…

  • Development and validation of a scale of healthy psychological effects of physical exercise among Chinese college students from a multidimensional mental health perspective

    Open Access•Feiyang Liu, Zhengguang Zhu et al.•ARTICLE•Frontiers in Public Health•2026

    Background Physical exercise promotes mental health among college students, but existing studies often assess general mental health or limited psychological indicators, making it difficult to capture comprehensive healthy psychological effects after exercise. This study aimed to develop and validate the Healthy Psychological Effects of Physical Exercise Scale for College Students . Methods An initial scale was developed through theoretical analys…

  • The relationship between disability and quality of life among older adults

    Open Access•Jing Zhu, Zhiqiang Feng et al.•ARTICLE•Frontiers in Public Health•2026

    Background The acceleration of population aging, especially in China, has led to a rapid growth in the number of older adults living with disabilities, posing significant challenges to public health and quality of life (QoL). From the perspective of the biopsychosocial framework, the adverse impact of disability (a biological and functional factor) on QoL has been well documented. However, the underlying mechanisms linking disability to QoL withi…

Apoptosis (2 works) · Biology (2 works) · Cancer Research (2 works) · DAPI (2 works) · In vivo (2 works) · Medicine (2 works) · Mental health (2 works) · Population (2 works) · Public health (2 works) · A549 cell (1 work)

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