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Yuan-Jian Yang

Biographic Data

ID7307290
NAMEYuan-Jian Yang
GIVEN NAMESYuan-Jian
FAMILY NAMEYang
SIGNATUREYANG Y
AFFILIATIONSJiangxi Mental Health Center
ORCID0000-0002-0175-5646
VERIFIEDYes
TOTAL WORKS6
TOTAL CITATIONS0
WORKS AS AUTHOR6
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2016
LATEST PUBLICATION YEAR2026
H-INDEX0
  • Changes in plasma hydrogen sulfide are associated with cognitive improvements in schizophrenia patients treated with atypical antipsychotics

    Open Access•You-Chang Huang, Yi-heng Li et al.•ARTICLE•Frontiers in Psychiatry•2026

    Background Hydrogen sulfide (H2S) acts as a neuromodulator in the brain and is shown to be associated with cognitive impairments in schizophrenia. Atypical antipsychotics can provide cognitive benefits for schizophrenia patients. This prospective observational study aims to investigate whether H 2 S signaling is involved in the cognitive improvement effects of atypical antipsychotics in patients with schizophrenia. Methods A total of 25 schizophr…

  • Lower serum insulin-like growth factor 2 level in patients with bipolar disorder is associated with the severity of manic symptoms during manic episodes

    Open Access•Seo-Hyeon Ye, Ying Zhao et al.•ARTICLE•Frontiers in Psychiatry•2024

    Lower serum IGF-2 levels were found in BD patients and correlated with the severity of the manic symptoms in these patients during manic episodes. These results suggest that reduced IGF-2 levels might be involved in the pathophysiology of BD, and serum IGF-2 could be a peripheral biomarker for the evaluation of the severity of manic symptoms in BD patients

  • Decreased Plasma Hydrogen Sulfide Level Is Associated With the Severity of Depression in Patients With Depressive Disorder

    Open Access•Yuan-Jian Yang, Chunnuan Chen et al.•ARTICLE•Frontiers in Psychiatry•2021

    Accumulating evidence has suggested a dysfunction of synaptic plasticity in the pathophysiology of depression. Hydrogen sulfide (H 2 S), an endogenous gasotransmitter that regulates synaptic plasticity, has been demonstrated to contribute to depressive-like behaviors in rodents. The current study investigated the relationship between plasma H 2 S levels and the depressive symptoms in patients with depression. Forty-seven depressed patients and 51…

  • Decreased Plasma Levels of Growth Differentiation Factor 11 in Patients With Schizophrenia

    Open Access•Yang Zhao-xi, Zhao-xi Yang et al.•ARTICLE•Frontiers in Psychiatry•2020

    Schizophrenia is linked with abnormal neurodevelopment, on which growth differentiation factor 11 (GDF-11) has a great impact. However, a direct evidence linking GDF-11 to the pathophysiology of schizophrenia is still lacking. The current study aimed to investigate the relationship between plasma GDF-11 levels and both psychopathological symptoms and cognitive function in schizophrenia. Eighty-seven schizophrenia patients and 76 healthy controls …

  • Treatment Responses of Cognitive Function and Plasma Asymmetric Dimethylarginine to Atypical Antipsychotic in Patients With Schizophrenia

    Open Access•Zhi-Min Yu, Ying Zhao et al.•ARTICLE•Frontiers in Psychiatry•2019

    Cognitive deficits represent a core feature of schizophrenia. Previous studies have demonstrated that plasma asymmetric dimethylarginine (ADMA) was increased in patients with schizophrenia and correlated with cognitive impairments. Atypical antipsychotics can produce cognitive benefits in schizophrenia patients. In this study, we conducted a prospective observation trial to explore whether plasma ADMA may serve as an indicator for evaluating cogn…

  • Chronic administration tetrahydroxystilbene glucoside promotes hippocampal memory and synaptic plasticity and activates ERKs, CaMKII and Sirt1/miR-134 in vivo

    Open Access•Tao Chen, Yuan-Jian Yang et al.•ARTICLE•Journal of Ethnopharmacology•2016

No prominent works on this page.

  • Chronic administration tetrahydroxystilbene glucoside promotes hippocampal memory and synaptic plasticity and activates ERKs, CaMKII and Sirt1/miR-134 in vivo

    Open Access•Tao Chen, Yuan-Jian Yang et al.•ARTICLE•Journal of Ethnopharmacology•2016

  • Treatment Responses of Cognitive Function and Plasma Asymmetric Dimethylarginine to Atypical Antipsychotic in Patients With Schizophrenia

    Open Access•Zhi-Min Yu, Ying Zhao et al.•ARTICLE•Frontiers in Psychiatry•2019

    Cognitive deficits represent a core feature of schizophrenia. Previous studies have demonstrated that plasma asymmetric dimethylarginine (ADMA) was increased in patients with schizophrenia and correlated with cognitive impairments. Atypical antipsychotics can produce cognitive benefits in schizophrenia patients. In this study, we conducted a prospective observation trial to explore whether plasma ADMA may serve as an indicator for evaluating cogn…

  • Decreased Plasma Levels of Growth Differentiation Factor 11 in Patients With Schizophrenia

    Open Access•Yang Zhao-xi, Zhao-xi Yang et al.•ARTICLE•Frontiers in Psychiatry•2020

    Schizophrenia is linked with abnormal neurodevelopment, on which growth differentiation factor 11 (GDF-11) has a great impact. However, a direct evidence linking GDF-11 to the pathophysiology of schizophrenia is still lacking. The current study aimed to investigate the relationship between plasma GDF-11 levels and both psychopathological symptoms and cognitive function in schizophrenia. Eighty-seven schizophrenia patients and 76 healthy controls …

  • Decreased Plasma Hydrogen Sulfide Level Is Associated With the Severity of Depression in Patients With Depressive Disorder

    Open Access•Yuan-Jian Yang, Chunnuan Chen et al.•ARTICLE•Frontiers in Psychiatry•2021

    Accumulating evidence has suggested a dysfunction of synaptic plasticity in the pathophysiology of depression. Hydrogen sulfide (H 2 S), an endogenous gasotransmitter that regulates synaptic plasticity, has been demonstrated to contribute to depressive-like behaviors in rodents. The current study investigated the relationship between plasma H 2 S levels and the depressive symptoms in patients with depression. Forty-seven depressed patients and 51…

  • Lower serum insulin-like growth factor 2 level in patients with bipolar disorder is associated with the severity of manic symptoms during manic episodes

    Open Access•Seo-Hyeon Ye, Ying Zhao et al.•ARTICLE•Frontiers in Psychiatry•2024

    Lower serum IGF-2 levels were found in BD patients and correlated with the severity of the manic symptoms in these patients during manic episodes. These results suggest that reduced IGF-2 levels might be involved in the pathophysiology of BD, and serum IGF-2 could be a peripheral biomarker for the evaluation of the severity of manic symptoms in BD patients

  • Changes in plasma hydrogen sulfide are associated with cognitive improvements in schizophrenia patients treated with atypical antipsychotics

    Open Access•You-Chang Huang, Yi-heng Li et al.•ARTICLE•Frontiers in Psychiatry•2026

    Background Hydrogen sulfide (H2S) acts as a neuromodulator in the brain and is shown to be associated with cognitive impairments in schizophrenia. Atypical antipsychotics can provide cognitive benefits for schizophrenia patients. This prospective observational study aims to investigate whether H 2 S signaling is involved in the cognitive improvement effects of atypical antipsychotics in patients with schizophrenia. Methods A total of 25 schizophr…

Medicine (5 works) · Clinical Psychology (4 works) · Clinical Psychology (4 works) · Internal Medicine (4 works) · Psychiatry (4 works) · Psychology (4 works) · Cognition (3 works) · Schizophrenia (object-oriented programming (3 works) · Antipsychotic (2 works) · Biology (2 works)

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