Alessio Squassina

Biographic Data

ID7378189
NAMEAlessio Squassina
GIVEN NAMESAlessio
FAMILY NAMESquassina
SIGNATURESQUASSINA A
AFFILIATIONSDalhousie University
ORCID0000-0001-7415-7607
VERIFIEDYes
TOTAL WORKS6
TOTAL CITATIONS0
AUTHOR COUNT6
EDITOR COUNT0
FIRST PUBLICATION YEAR2018
LATEST PUBLICATION YEAR2025
H-INDEX0

  • Identifying molecular signatures of post-traumatic stress disorder vulnerability and progression in a longitudinal study

    Open AccessFederico Suprani, Pasquale Paribello et al.ARTICLEFrontiers in Psychiatry2025

    Post-Traumatic Stress Disorder (PTSD) is a highly debilitating psychiatric disorder, which develops in a subset of trauma-exposed individuals. Patients with PTSD fail to extinguish fear responses to no-longer dangerous stimuli and develop enduring experiences of fear and anxiety. To advance the understanding of PTSD neurobiology, longitudinal and comprehensive clinical and molecular data are needed. Here we present the protocol of the project "Re…

  • Factors influencing patient decision-making on a multimodal precision medicine algorithm for depression

    Open AccessRosa Glaser, Johannes C S Zang et al.ARTICLEFrontiers in Psychiatry2025

    While patients are open to the use of a multimodal precision medicine algorithm for MDD, they emphasised the need for individualised, transparent communication and emotional support. The results highlight the importance of patient-centred communication strategies and guidelines for the ethical implementation of precision psychiatry

  • Attitudes towards a multimodal precision medicine algorithm for predicting treatment response in depression

    Open AccessViktor T H Wahner, Johannes C S Zang et al.ARTICLEFrontiers in Psychiatry2025

    Overall, participants indicated a large degree of acceptance towards the application of a multimodal precision medicine algorithm. Although limited by the hypothetical nature of the decision scenario, this study provides valuable perspectives from different stakeholders. Future research should move beyond attitudes and address further implementation hurdles that need to be overcome for the successful implementation of novel precision psychiatry a…

  • The clock is ticking on schizophrenia

    Open AccessGiacomo Mercuriali, Lorenzo Lodde et al.ARTICLEFrontiers in Psychiatry2024

    This project has the potential to identify some typical SCZ symptomatic clusters that will be more stringently associated with variations in the Trp-MLT-Kyn/inflammatory system and with a better response to cognitive remediation therapy. Moreover, in a future perspective, it may highlight a group of patients who may benefit from a pharmacological treatment aiming at reinstating the physiological Trp to MLT and Kyn system. Therefore, it has the po…

  • An integrated precision medicine approach in major depressive disorder

    Open AccessBernhard T Baune, Alessandra Minelli et al.ARTICLEFrontiers in Psychiatry2024

    Major depressive disorder (MDD) is the most common psychiatric disease worldwide with a huge socio-economic impact. Pharmacotherapy represents the most common option among the first-line treatment choice; however, only about one third of patients respond to the first trial and about 30% are classified as treatment-resistant depression (TRD). TRD is associated with specific clinical features and genetic/gene expression signatures. To date, single …

  • Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder

    Open AccessCéline S Reinbold, Andreas J Forstner et al.ARTICLEFrontiers in Psychiatry2018

    Bipolar disorder (BD) is a common, highly heritable neuropsychiatric disease characterized by recurrent episodes of mania and depression. Lithium is the best-established long-term treatment for BD, even though individual response is highly variable. Evidence suggests that some of this variability has a genetic basis. This is supported by the largest genome-wide association study (GWAS) of lithium response to date conducted by the International Co…