Susan G Leckband
Biographic Data
| ID | 7386685 |
|---|---|
| NAME | Susan G Leckband |
| GIVEN NAMES | Susan G |
| FAMILY NAME | Leckband |
| SIGNATURE | LECKBAND S G |
| AFFILIATIONS | VA San Diego Healthcare System |
| ORCID | 0000-0001-8748-5220 |
| VERIFIED | Yes |
| TOTAL WORKS | 3 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 3 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2002 |
| LATEST PUBLICATION YEAR | 2018 |
| H-INDEX | 0 |
Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder
Bipolar disorder (BD) is a common, highly heritable neuropsychiatric disease characterized by recurrent episodes of mania and depression. Lithium is the best-established long-term treatment for BD, even though individual response is highly variable. Evidence suggests that some of this variability has a genetic basis. This is supported by the largest genome-wide association study (GWAS) of lithium response to date conducted by the International Co…
Does the Time of Drug Administration Alter the Metabolic Risk of Aripiprazole
Antipsychotic drugs cause metabolic abnormalities through a mechanism that involves antagonism of D 2 dopamine receptors (D 2 R). Under healthy conditions, insulin release follows a circadian rhythm and is low at night, and in pancreatic beta-cells, D 2 Rs negatively regulate insulin release. Since they are sedating, many antipsychotics are dosed at night. However, the resulting reduction in overnight D 2 R activity may disrupt 24 h rhythms in in…
Prevalence of and Risk Factors for Medication Nonadherence in Patients With Schizophrenia
OBJECTIVE: Nonadherence to prescribed antipsychotic medications places patients with schizophrenia at a greatly increased risk of illness exacerbation and rehospitalization. Identification of risk factors for nonadherence is an initial step toward designing effective interventions. This article reviews recent literature on the prevalence of and risk factors for medication nonadherence in patients with schizophrenia. DATA SOURCES: We searched the …
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Prevalence of and Risk Factors for Medication Nonadherence in Patients With Schizophrenia
OBJECTIVE: Nonadherence to prescribed antipsychotic medications places patients with schizophrenia at a greatly increased risk of illness exacerbation and rehospitalization. Identification of risk factors for nonadherence is an initial step toward designing effective interventions. This article reviews recent literature on the prevalence of and risk factors for medication nonadherence in patients with schizophrenia. DATA SOURCES: We searched the …
Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder
Bipolar disorder (BD) is a common, highly heritable neuropsychiatric disease characterized by recurrent episodes of mania and depression. Lithium is the best-established long-term treatment for BD, even though individual response is highly variable. Evidence suggests that some of this variability has a genetic basis. This is supported by the largest genome-wide association study (GWAS) of lithium response to date conducted by the International Co…
Does the Time of Drug Administration Alter the Metabolic Risk of Aripiprazole
Antipsychotic drugs cause metabolic abnormalities through a mechanism that involves antagonism of D 2 dopamine receptors (D 2 R). Under healthy conditions, insulin release follows a circadian rhythm and is low at night, and in pancreatic beta-cells, D 2 Rs negatively regulate insulin release. Since they are sedating, many antipsychotics are dosed at night. However, the resulting reduction in overnight D 2 R activity may disrupt 24 h rhythms in in…
Medicine (3 works) · Psychiatry (3 works) · Schizophrenia research and treatment (2 works) · Antipsychotic (1 work) · Aripiprazole (1 work) · Biology (1 work) · Bipolar disorder (1 work) · Bipolar Disorder and Treatment (1 work) · CINAHL (1 work) · Circadian rhythm and melatonin (1 work)