Gian Franco De Stefano
Biographic Data
| ID | 74867 |
|---|---|
| NAME | Gian Franco De Stefano |
| GIVEN NAMES | Gian Franco |
| FAMILY NAME | De Stefano |
| SIGNATURE | DE STEFANO G F |
| AFFILIATIONS | University of Rome Tor Vergata |
| VERIFIED | No |
| TOTAL WORKS | 31 |
| TOTAL CITATIONS | 20 |
| AUTHOR COUNT | 31 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1973 |
| LATEST PUBLICATION YEAR | 2016 |
| H-INDEX | 3 |
Linking between genetic structure and geographical distance: Study of the maternal gene pool in the Ethiopian population
Background The correlation between genetics and geographical distance has already been examined through the study of the dispersion of human populations, especially in terms of uniparental genetic markers. Aim The present work characterises, at the level of the mitochondrial DNA (mtDNA), two new samples of Amhara and Oromo populations from Ethiopia to evaluate the possible pattern of distribution for mtDNA variation and to test the hypothesis of …
Growth variation, final height and secular trend. Proceedings of the 17th Aschauer Soiree, 7th November 2009
Obituary Page
Genetic Variation at Apolipoprotein E Locus in Ethiopia: An E5 Variant Corresponds to Two Different Mutant Alleles: E*5 (Glu212Lys) and E*5 (Gln204Lys; Cys112Arg)
A previous investigation on apolipoprotein E polymorphism in the Ethiopian population highlighted the presence of a further variant allele named E*5 in addition to the three common alleles. The variant is considered rare elsewhere but has a frequency of more than 1% in this population. Now characterized by gene sequencing and restriction isotyping in many members of the families of the original carriers, the variant isoform has actually been foun…
New Data on the World Distribution of Paraoxonase ( PON1 Gln 192--Arg) Gene Frequencies
The physiological role of human paraoxonase (PON), a serum enzyme that hydrolyzes organophosphate insecticides and nerve agents, is not clear. Of the three genes in the paraoxonase gene family, PON1 shows a polymorphism, Gln 192 --> Arg, governed by two common alleles named *Q and *R. These determine two different isoforms associated, respectively, with lower and higher activity towards paraoxon, a toxic metabolic product of the insecticide parat…
Analysis of three RFLPs of the COL1A2 (Type I Collagen) in the Amhara and the Oromo of Ethiopia
The present findings suggest the presence of a differential level of genetic relatedness with south-Saharan peoples in the two Ethiopian groups, which could reflect their different history and seems to indicate the existence of genetic sub-structure within the country
Genetic Differentiation in South Amerindians Is Related to Environmental and Cultural Diversity: Evidence from the Y Chromosome
Red Cell Enzyme Polymorphisms in Friuli Venezia Giulia (Northeast Italy)
Seven erythrocyte enzyme polymorphisms (ACP1, ADA, ESD, GLO1, PGD, PGM1 and PGM2) were investigated in a sample of 673 unrelated adult individuals from Friuli Venezia Giulia (or Friuli) and Istria. The gene frequencies found in the four provincial samples of Friuli and Istria fall within the range previously reported for Italy, showing a genetic homogeneity among the considered samples. However, comparisons with data from ex-Yugoslavian samples--…
DNA and cultural heritage
An investigation of human apolipoproteins B and E polymorphisms in two African populations from Ethiopia and Benin
Three polymorphisms (XbaI, EcoRI, and Ins/Del) of the apolipoprotein B (APOB) gene and the polymorphism of apolipoprotein E (APOE) were investigated in two population samples of Amhara and Oromo origin from Ethiopia, and in two population samples of Bariba and Berba origin from Benin. No heterogeneity was observed within each major group. The cumulated frequencies of the APOB X+, R+, and D alleles for the Ethiopia and the Benin groups were 0.268 …
Genetic population structure of two African-Ecuadorian communities of Esmeraldas
The genetic structure of two African-Ecuadorian communities, Rio Cayapas and Viche (Esmeraldas province, northwest Ecuador), was studied on the basis of ACP1, ADA, AK1, CA2, ESD, GLO1, G6PD, PGD, and PGM1 subtypes and thermostability, PGM2, HBbeta, F13A, F13B, ORM1, AHSG, C6, C7, and APOC2 gene frequency, and migration data on 255 individuals. The fixation index of Wright (F(ST)), correspondence, and genetic distance analysis were applied to comp…
Biodemography in Siena, Italy
Data were obtained on surnames of the parents and places of birth of the parents and grandparents of children in Siena, Italy. Isonymy and total inbreeding coefficient, and their random and non-random components, are 0·005, 0·00125, 0·00019 and 0·00106, respectively. Isonymy and inbreeding figures are similar to those of other medium-sized Italian towns, while higher values have been reported for Italian villages and Italian ethnic minorities. Ci…
GM and KM allotypes in nine population samples of Sicily
Serum samples of 864 unrelated healthy male and female individuals belonging to nine provinces of Sicily were types for Glm (1,2,3,17), G3m (5,10,11,13,14,15,16,21), and KM (1). With the exception of the Trapani sample these samples are characterized by the presence of five GM haplotypes: GM*1,17;21,26; GM*1,2,17;21,26; GM*1,3;5,10,11,13,14,26; GM*3;5,10,13,14,26; and GM*1,17;10,11,13,15,16. The interpopulation variability in the distribution of …
An anthropogenetic study on the Oromo and Amhara of central Ethiopia
Blood samples from members of the Oromo and Amhara ethnic groups of central Ethiopia were tested for 10 erythrocyte protein systems: ACP1, ADA, AK1, CA2, ESD, G6PD, GLO1, HBβ, PGD, and PGM1. Differences between the two samples were relatively slight and not statistically significant. Gene frequency distributions were then analyzed in the context of the genetics of the African and Arabian peoples. Considering the erythrocyte enzyme data, the Oromo…
Distribution of some erythrocyte enzyme polymorphisms in Emilia Romagna (Northern Italy)
In the last decades erythrocyte and serum genetic polymorphisms have been extensively analysed in many Italian population samples (a wide and up-to-date review of data in literature was published in 1989 by Piazza et al.). In spite of this, some geographical areas need further research and, in order to contribute to filling these gaps, we started a wide survey in Italy some years ago using the most polymorphic erythrocyte and serum markers. Many …
The Cayapa Indians of Ecuador: A population study of seven protein genetic polymorphisms
The Cayapa Indians are a population of 3600 individuals living in Ecuador, along the Cayapas River and its tributaries. They are thought to have migrated from the Andes, north of Quito, and settled in the Cayapas area five centuries ago as a consequence of Inca expansion and of the Spanish conquest. In order to study the genetic structure of the Cayapa and their relationships with other native American peoples, and to enquire on the possibility o…
Genetic relationships among the Native American populations
Red cell antigen data were used to investigate the genetic relationship among the Native American populations and their affinities with Siberian and Eastern Asian populations. Correspondence analysis showed a clear subdivision of all the Native American populations into three clear-cut clusters corresponding to the three linguistic families (identified by Greenberg)--Amerind, Na-Dene and Eskimo-Aleut. This result, as well as the close genetic res…
Marriage distances among the Afroamericans of Bluefields, Nicaragua
In a sample of 311 couples from the Afroamerican community of Bluefields, Eastern Nicaragua, the distribution of matrimonial distance shows a deviation from the leptokurtic rule. This results from assortative mating among the population.
Investigations of the variability of four genetic serum protein markers (HP; TF, GC and PI subtypes) in Italy
14 population samples from various Italian regions with a total of 2.577 unrelated male and female individuals were typed for four polymorphic serum protein polymorphisms: HP, and TF, GC and PI subtypes. The regional distribution of the allele frequencies of these four polymorphisms shows a considerable heterogeneity, which is for the most part statistically significant, thus indicating an obvious genetic variability of the population of the Ital…
Genetic structure of the population of Sicily
Genetic heterogeneity within Sicily was investigated on the basis of ACP1, ADA, ESD, GLO1, PGD, PGM1, PGM2, SODA, ABO, and MN gene frequencies, and compared to those of other regions of Italy for which these same loci have been examined. Correspondence analysis revealed no differences within the island, at least at the provincial level, but showed genetic differentiation among Italian regions, distinctly clustering northern, central, and southern…
Gm and Km allotypes in four Sardinian population samples
Serum samples of 683 unrelated male and female individuals of four Sardinian population samples (Sassari, Nuoro, Oristano and Cagliari) were typed for G 1 m (1, 2, 3, 17), G 3 m (5, 6, 10, 11, 13, 14, 15, 16, 21, 26), and Km (1). Phenotype, haplotype (Gm), and allele frequencies (Km), respectively, show a remarkable variability between these four population samples. Comparisons with other Italian populations reveal the considerable genetic differ…
Migration pattern and genetic marker distribution of the Afro-American population of Bluefields, Nicaragua
On a sample of the population of mixed African ancestry living in Bluefields, Nicaragua, the pattern of migration and the distribution of red cell and serum genetic markers have been studied. It is concluded that, in spite of a considerable level of internal and external migration, a distinctive genetic structure is maintained by the population. Moreover, a strongly negative assortative mating can be observed between people inhabiting the western…
Genetic Variation and Its Maintenance with Particular Reference to Tropical Populations
1. Genetic diversity - its dimensions 2. Genetic diversity - its origin and maintenance 3. Genetic diversity - applications and problems of complex characters
Digital dermatoglyphics in two Afro-American communities of Central America
The present report provides analytical data of digital dermatoglyphics on 150 subjects (79 males, 71 females) from Bluefields, Nicaragua and 146 (98 males, 48 females) from Livingston, Guatemala. They were classified as belonging to three sub-samples: Negroes (Bluefields) or Black-Caribs (Livingston), Ladinos and Creoles.However due to the very small size of some sub-samples, the findings, related to brief demographical and ethno-historical persp…
Variations in form of the hypoglossal canal
Variation in the nature and extent of division of the hypoglossal canal can be classified by a simple scoring scheme. Applied to three series of crania of differing provenance, the results indicate a continuity in expression of the trait rather than the dichotomous character utilized in previous studies. The similarity in results in these three populations, of widely differing environment, suggests fairly strict canalization of development
Genetic structure of the population of Sicily
Genetic heterogeneity within Sicily was investigated on the basis of ACP1, ADA, ESD, GLO1, PGD, PGM1, PGM2, SODA, ABO, and MN gene frequencies, and compared to those of other regions of Italy for which these same loci have been examined. Correspondence analysis revealed no differences within the island, at least at the provincial level, but showed genetic differentiation among Italian regions, distinctly clustering northern, central, and southern…
Gm and Km allotypes in four Sardinian population samples
Serum samples of 683 unrelated male and female individuals of four Sardinian population samples (Sassari, Nuoro, Oristano and Cagliari) were typed for G 1 m (1, 2, 3, 17), G 3 m (5, 6, 10, 11, 13, 14, 15, 16, 21, 26), and Km (1). Phenotype, haplotype (Gm), and allele frequencies (Km), respectively, show a remarkable variability between these four population samples. Comparisons with other Italian populations reveal the considerable genetic differ…
Reflections on interobserver differences in scoring non-metric cranial traits (with practical examples)
Variations in form of the hypoglossal canal
Variation in the nature and extent of division of the hypoglossal canal can be classified by a simple scoring scheme. Applied to three series of crania of differing provenance, the results indicate a continuity in expression of the trait rather than the dichotomous character utilized in previous studies. The similarity in results in these three populations, of widely differing environment, suggests fairly strict canalization of development
DNA and cultural heritage
Genetic relationships among the Native American populations
Red cell antigen data were used to investigate the genetic relationship among the Native American populations and their affinities with Siberian and Eastern Asian populations. Correspondence analysis showed a clear subdivision of all the Native American populations into three clear-cut clusters corresponding to the three linguistic families (identified by Greenberg)--Amerind, Na-Dene and Eskimo-Aleut. This result, as well as the close genetic res…
Inter- and intra-observer variability in the interpretation of the “discrete” characters of the skull
A study of morphological and genetic distance among four Indian villages of Nicaragua
A study of morphological and genetic distance among four Indian villages of Nicaragua
First data on the nuclear DNA content (Feulgen-positive material) of Perodicticus potto
Variations du caryotype et modifications cytochimiques du nucleus dans les lymphocytes chez des sujets jeunes et âgés
De Stefano G. F., Guerci A. Variations du caryotype et modifications cytochimiques du nucleus dans les lymphocytes chez des sujets jeunes et âgés. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, XIII° Série. Tome 2 fascicule 3, 1975. pp. 201-210
P.T.C. tasting among three Indian groups of Nicaragua
Ninety‐six Miskito, 85 Sumo and 79 Rama Indians were tested for P.T.C. taste ability according to a modification of Harris and Kalmus' sorting technique. Miskito's “non‐taster” high frequency approach values reported for some highly inbred Central and South American Indian populations, while Rama's and Sumo's figures appear in agreement with values reported for other relatively pure Amerindians
Inter- and intra-observer variability in the interpretation of the “discrete” characters of the skull
Reflections on interobserver differences in scoring non-metric cranial traits (with practical examples)
Variations in form of the hypoglossal canal
Variation in the nature and extent of division of the hypoglossal canal can be classified by a simple scoring scheme. Applied to three series of crania of differing provenance, the results indicate a continuity in expression of the trait rather than the dichotomous character utilized in previous studies. The similarity in results in these three populations, of widely differing environment, suggests fairly strict canalization of development
Digital dermatoglyphics in two Afro-American communities of Central America
The present report provides analytical data of digital dermatoglyphics on 150 subjects (79 males, 71 females) from Bluefields, Nicaragua and 146 (98 males, 48 females) from Livingston, Guatemala. They were classified as belonging to three sub-samples: Negroes (Bluefields) or Black-Caribs (Livingston), Ladinos and Creoles.However due to the very small size of some sub-samples, the findings, related to brief demographical and ethno-historical persp…
Genetic Variation and Its Maintenance with Particular Reference to Tropical Populations
1. Genetic diversity - its dimensions 2. Genetic diversity - its origin and maintenance 3. Genetic diversity - applications and problems of complex characters
Migration pattern and genetic marker distribution of the Afro-American population of Bluefields, Nicaragua
On a sample of the population of mixed African ancestry living in Bluefields, Nicaragua, the pattern of migration and the distribution of red cell and serum genetic markers have been studied. It is concluded that, in spite of a considerable level of internal and external migration, a distinctive genetic structure is maintained by the population. Moreover, a strongly negative assortative mating can be observed between people inhabiting the western…
Gm and Km allotypes in four Sardinian population samples
Serum samples of 683 unrelated male and female individuals of four Sardinian population samples (Sassari, Nuoro, Oristano and Cagliari) were typed for G 1 m (1, 2, 3, 17), G 3 m (5, 6, 10, 11, 13, 14, 15, 16, 21, 26), and Km (1). Phenotype, haplotype (Gm), and allele frequencies (Km), respectively, show a remarkable variability between these four population samples. Comparisons with other Italian populations reveal the considerable genetic differ…
Investigations of the variability of four genetic serum protein markers (HP; TF, GC and PI subtypes) in Italy
14 population samples from various Italian regions with a total of 2.577 unrelated male and female individuals were typed for four polymorphic serum protein polymorphisms: HP, and TF, GC and PI subtypes. The regional distribution of the allele frequencies of these four polymorphisms shows a considerable heterogeneity, which is for the most part statistically significant, thus indicating an obvious genetic variability of the population of the Ital…
Genetic structure of the population of Sicily
Genetic heterogeneity within Sicily was investigated on the basis of ACP1, ADA, ESD, GLO1, PGD, PGM1, PGM2, SODA, ABO, and MN gene frequencies, and compared to those of other regions of Italy for which these same loci have been examined. Correspondence analysis revealed no differences within the island, at least at the provincial level, but showed genetic differentiation among Italian regions, distinctly clustering northern, central, and southern…
Marriage distances among the Afroamericans of Bluefields, Nicaragua
In a sample of 311 couples from the Afroamerican community of Bluefields, Eastern Nicaragua, the distribution of matrimonial distance shows a deviation from the leptokurtic rule. This results from assortative mating among the population.
The Cayapa Indians of Ecuador: A population study of seven protein genetic polymorphisms
The Cayapa Indians are a population of 3600 individuals living in Ecuador, along the Cayapas River and its tributaries. They are thought to have migrated from the Andes, north of Quito, and settled in the Cayapas area five centuries ago as a consequence of Inca expansion and of the Spanish conquest. In order to study the genetic structure of the Cayapa and their relationships with other native American peoples, and to enquire on the possibility o…
Genetic relationships among the Native American populations
Red cell antigen data were used to investigate the genetic relationship among the Native American populations and their affinities with Siberian and Eastern Asian populations. Correspondence analysis showed a clear subdivision of all the Native American populations into three clear-cut clusters corresponding to the three linguistic families (identified by Greenberg)--Amerind, Na-Dene and Eskimo-Aleut. This result, as well as the close genetic res…
Distribution of some erythrocyte enzyme polymorphisms in Emilia Romagna (Northern Italy)
In the last decades erythrocyte and serum genetic polymorphisms have been extensively analysed in many Italian population samples (a wide and up-to-date review of data in literature was published in 1989 by Piazza et al.). In spite of this, some geographical areas need further research and, in order to contribute to filling these gaps, we started a wide survey in Italy some years ago using the most polymorphic erythrocyte and serum markers. Many …
An anthropogenetic study on the Oromo and Amhara of central Ethiopia
Blood samples from members of the Oromo and Amhara ethnic groups of central Ethiopia were tested for 10 erythrocyte protein systems: ACP1, ADA, AK1, CA2, ESD, G6PD, GLO1, HBβ, PGD, and PGM1. Differences between the two samples were relatively slight and not statistically significant. Gene frequency distributions were then analyzed in the context of the genetics of the African and Arabian peoples. Considering the erythrocyte enzyme data, the Oromo…
GM and KM allotypes in nine population samples of Sicily
Serum samples of 864 unrelated healthy male and female individuals belonging to nine provinces of Sicily were types for Glm (1,2,3,17), G3m (5,10,11,13,14,15,16,21), and KM (1). With the exception of the Trapani sample these samples are characterized by the presence of five GM haplotypes: GM*1,17;21,26; GM*1,2,17;21,26; GM*1,3;5,10,11,13,14,26; GM*3;5,10,13,14,26; and GM*1,17;10,11,13,15,16. The interpopulation variability in the distribution of …
Biodemography in Siena, Italy
Data were obtained on surnames of the parents and places of birth of the parents and grandparents of children in Siena, Italy. Isonymy and total inbreeding coefficient, and their random and non-random components, are 0·005, 0·00125, 0·00019 and 0·00106, respectively. Isonymy and inbreeding figures are similar to those of other medium-sized Italian towns, while higher values have been reported for Italian villages and Italian ethnic minorities. Ci…
An investigation of human apolipoproteins B and E polymorphisms in two African populations from Ethiopia and Benin
Three polymorphisms (XbaI, EcoRI, and Ins/Del) of the apolipoprotein B (APOB) gene and the polymorphism of apolipoprotein E (APOE) were investigated in two population samples of Amhara and Oromo origin from Ethiopia, and in two population samples of Bariba and Berba origin from Benin. No heterogeneity was observed within each major group. The cumulated frequencies of the APOB X+, R+, and D alleles for the Ethiopia and the Benin groups were 0.268 …
Genetic population structure of two African-Ecuadorian communities of Esmeraldas
The genetic structure of two African-Ecuadorian communities, Rio Cayapas and Viche (Esmeraldas province, northwest Ecuador), was studied on the basis of ACP1, ADA, AK1, CA2, ESD, GLO1, G6PD, PGD, and PGM1 subtypes and thermostability, PGM2, HBbeta, F13A, F13B, ORM1, AHSG, C6, C7, and APOC2 gene frequency, and migration data on 255 individuals. The fixation index of Wright (F(ST)), correspondence, and genetic distance analysis were applied to comp…
Red Cell Enzyme Polymorphisms in Friuli Venezia Giulia (Northeast Italy)
Seven erythrocyte enzyme polymorphisms (ACP1, ADA, ESD, GLO1, PGD, PGM1 and PGM2) were investigated in a sample of 673 unrelated adult individuals from Friuli Venezia Giulia (or Friuli) and Istria. The gene frequencies found in the four provincial samples of Friuli and Istria fall within the range previously reported for Italy, showing a genetic homogeneity among the considered samples. However, comparisons with data from ex-Yugoslavian samples--…
DNA and cultural heritage
Genetic Differentiation in South Amerindians Is Related to Environmental and Cultural Diversity: Evidence from the Y Chromosome
Biology (26 works) · Demography (20 works) · Geography (17 works) · Population (16 works) · Sociology (13 works) · Genetics (12 works) · Evolutionary biology (11 works) · Gene (11 works) · Genetic variation (10 works) · Genetics (10 works)