Mosepele Mosepele
Biographic Data
| ID | 7596656 |
|---|---|
| NAME | Mosepele Mosepele |
| GIVEN NAMES | Mosepele |
| FAMILY NAME | Mosepele |
| SIGNATURE | MOSEPELE M |
| AFFILIATIONS | University of Botswana |
| ORCID | 0000-0002-6051-0999 |
| VERIFIED | Yes |
| TOTAL WORKS | 13 |
| TOTAL CITATIONS | 3 |
| AUTHOR COUNT | 13 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2009 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Integrated epidemiologic investigation and genomic confirmation of a Klebsiella pneumoniae neonatal sepsis outbreak in Botswana
Klebsiella pneumoniae ( Kpn ) is a major cause of infant mortality worldwide, with most transmission occurring among hospitalized neonates in low- and middle-income countries where infections caused by multidrug-resistant Kpn (MDR- Kpn ) are increasingly common. We hypothesized that integrating laboratory surveillance for neonatal colonization and infection, real-time epidemiologic investigations, and whole-genome sequencing (WGS) could identify …
Self-reported sleep quality and frailty in middle-aged people living with HIV in an African setting
People living with HIV (PLWH) are at increased risk of frailty, yet the role of sleep disturbances in this risk remains underexplored. In this cross-sectional study, we aimed to evaluate self-reported sleep quality in PLWH and relevance to frailty in a high HIV-prevalence setting within Africa. We enrolled 50 PLWH on suppressive antiretroviral therapy (age: 56.9 ± 4.4 years; 26 females) and 50 matched HIV-seronegative controls (age: 56.6 ± 4.3 ye…
Spatial distribution of central obesity in rural and peri urban communities of Botswana
gov/study/NCT01965470?tab=history&a=4
Advancing the course of HIV genomics research in Africa
BOX The use of genomics methods and technologies for HIV research and public health holds potential in reducing the HIV burden in sub-Saharan Africa
Admission screening for extended-spectrum cephalosporin-resistant and carbapenem-resistant Enterobacterales colonization at a referral hospital in Botswana
Extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) and carbapenem-resistant Enterobacterales (CRE) are significant contributors to infection-related mortality in low- and middle-income countries. Colonization with ESCrE and/or CRE can precede infection and serve as a reservoir for transmission within healthcare facilities and the community.We conducted a 12-month period-prevalence study, screening patients for ESCrE and CRE upon a…
Age and sources of information variations and similarities on awareness of treatment and prevention of stroke among public and outpatients in Sub-Saharan Africa
Results call for strategic educational stroke campaigns using best information relaying tool for each age and respondents' group
Internalized HIV Stigma, Sleep Problems, and Depressive Symptoms in People with HIV in Botswana
This study investigates the impact of internalized HIV stigma on sleep problems and depression in people living with HIV (PLWH) in Botswana. It also explores whether sleep problems mediate the relationship between internalized HIV stigma and depressive symptoms, given that sleep disturbance is a symptom of depression and often predates a depressive episode. Secondary analysis was conducted using baseline data from a pilot randomized controlled tr…
Self-reported cardiovascular disease risk factor screening among people living with HIV vs. members of the general population in Botswana
PLWH were almost two times more likely to have been previously screened for CVDRFs than those without HIV, indicating a need for universal scale-up of integrated management and prevention of CVDs in the HIV-uninfected population
HIV self-testing may overcome stigma and other barriers to HIV testing among higher-socioeconomic status men in Botswana
In Botswana, HIV prevalence is 20.3% among those between 15 and 49 years old, and in sub-Saharan Africa, higher income has been associated with increased HIV risk. We qualitatively explored barriers to HIV testing and acceptability of HIV self-testing (HIVST) among higher socio-economic status (SES) men in Botswana. Twenty higher SES men (10 tested, 10 not tested recently) participated in semi-structured interviews and 10 men participated in asyn…
Identifying "What Matters Most" to Men in Botswana to Promote Resistance to HIV-Related Stigma
Despite a comprehensive national program of free HIV services, men living with HIV in Botswana participate at lower rates and have worse outcomes than women. Directed content analysis of five focus groups ( n = 38) and 50 in-depth interviews with men and women with known and unknown HIV status in Gaborone, Botswana in 2017 used the "what matters most" (WMM) and "structural vulnerability" frameworks to examine how the most valued cultural aspects …
Depression in HIV-Positive Women in Gaborone, Botswana
This cross-sectional study measured prevalence of depression and suicide ideation in 62 randomly selected HIV-positive (HIV+) women in Botswana, a resource-limited country at the center of the HIV/AIDS epidemic. They were administered two screening measures of depression, an inventory of activities of daily living (ADL), and subjective questionnaire of cognitive functioning. Results show that the two screening measures are useful for detecting de…
Mutually Beneficial Global Health Electives
Case Adina and Jessica are third-year medical students on the same team during their medicine rotation. One day at lunch, Jessica begins to tell Adina about her plans to do a global health elective over their summer break. After a year of clerkships, she is excited to travel to Thailand to see the way medicine works in a developing nation. She thinks going abroad will strengthen her residency application and give her an opportunity to practice cl…
Depression Among HIV-Positive Individuals in Botswana
Identifying "What Matters Most" to Men in Botswana to Promote Resistance to HIV-Related Stigma
Despite a comprehensive national program of free HIV services, men living with HIV in Botswana participate at lower rates and have worse outcomes than women. Directed content analysis of five focus groups ( n = 38) and 50 in-depth interviews with men and women with known and unknown HIV status in Gaborone, Botswana in 2017 used the "what matters most" (WMM) and "structural vulnerability" frameworks to examine how the most valued cultural aspects …
Depression Among HIV-Positive Individuals in Botswana
Mutually Beneficial Global Health Electives
Case Adina and Jessica are third-year medical students on the same team during their medicine rotation. One day at lunch, Jessica begins to tell Adina about her plans to do a global health elective over their summer break. After a year of clerkships, she is excited to travel to Thailand to see the way medicine works in a developing nation. She thinks going abroad will strengthen her residency application and give her an opportunity to practice cl…
Depression in HIV-Positive Women in Gaborone, Botswana
This cross-sectional study measured prevalence of depression and suicide ideation in 62 randomly selected HIV-positive (HIV+) women in Botswana, a resource-limited country at the center of the HIV/AIDS epidemic. They were administered two screening measures of depression, an inventory of activities of daily living (ADL), and subjective questionnaire of cognitive functioning. Results show that the two screening measures are useful for detecting de…
HIV self-testing may overcome stigma and other barriers to HIV testing among higher-socioeconomic status men in Botswana
In Botswana, HIV prevalence is 20.3% among those between 15 and 49 years old, and in sub-Saharan Africa, higher income has been associated with increased HIV risk. We qualitatively explored barriers to HIV testing and acceptability of HIV self-testing (HIVST) among higher socio-economic status (SES) men in Botswana. Twenty higher SES men (10 tested, 10 not tested recently) participated in semi-structured interviews and 10 men participated in asyn…
Identifying "What Matters Most" to Men in Botswana to Promote Resistance to HIV-Related Stigma
Despite a comprehensive national program of free HIV services, men living with HIV in Botswana participate at lower rates and have worse outcomes than women. Directed content analysis of five focus groups ( n = 38) and 50 in-depth interviews with men and women with known and unknown HIV status in Gaborone, Botswana in 2017 used the "what matters most" (WMM) and "structural vulnerability" frameworks to examine how the most valued cultural aspects …
Self-reported cardiovascular disease risk factor screening among people living with HIV vs. members of the general population in Botswana
PLWH were almost two times more likely to have been previously screened for CVDRFs than those without HIV, indicating a need for universal scale-up of integrated management and prevention of CVDs in the HIV-uninfected population
Advancing the course of HIV genomics research in Africa
BOX The use of genomics methods and technologies for HIV research and public health holds potential in reducing the HIV burden in sub-Saharan Africa
Admission screening for extended-spectrum cephalosporin-resistant and carbapenem-resistant Enterobacterales colonization at a referral hospital in Botswana
Extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) and carbapenem-resistant Enterobacterales (CRE) are significant contributors to infection-related mortality in low- and middle-income countries. Colonization with ESCrE and/or CRE can precede infection and serve as a reservoir for transmission within healthcare facilities and the community.We conducted a 12-month period-prevalence study, screening patients for ESCrE and CRE upon a…
Age and sources of information variations and similarities on awareness of treatment and prevention of stroke among public and outpatients in Sub-Saharan Africa
Results call for strategic educational stroke campaigns using best information relaying tool for each age and respondents' group
Internalized HIV Stigma, Sleep Problems, and Depressive Symptoms in People with HIV in Botswana
This study investigates the impact of internalized HIV stigma on sleep problems and depression in people living with HIV (PLWH) in Botswana. It also explores whether sleep problems mediate the relationship between internalized HIV stigma and depressive symptoms, given that sleep disturbance is a symptom of depression and often predates a depressive episode. Secondary analysis was conducted using baseline data from a pilot randomized controlled tr…
Integrated epidemiologic investigation and genomic confirmation of a Klebsiella pneumoniae neonatal sepsis outbreak in Botswana
Klebsiella pneumoniae ( Kpn ) is a major cause of infant mortality worldwide, with most transmission occurring among hospitalized neonates in low- and middle-income countries where infections caused by multidrug-resistant Kpn (MDR- Kpn ) are increasingly common. We hypothesized that integrating laboratory surveillance for neonatal colonization and infection, real-time epidemiologic investigations, and whole-genome sequencing (WGS) could identify …
Self-reported sleep quality and frailty in middle-aged people living with HIV in an African setting
People living with HIV (PLWH) are at increased risk of frailty, yet the role of sleep disturbances in this risk remains underexplored. In this cross-sectional study, we aimed to evaluate self-reported sleep quality in PLWH and relevance to frailty in a high HIV-prevalence setting within Africa. We enrolled 50 PLWH on suppressive antiretroviral therapy (age: 56.9 ± 4.4 years; 26 females) and 50 matched HIV-seronegative controls (age: 56.6 ± 4.3 ye…
Spatial distribution of central obesity in rural and peri urban communities of Botswana
gov/study/NCT01965470?tab=history&a=4
Medicine (9 works) · HIV/AIDS Research and Interventions (7 works) · Public health (7 works) · Family medicine (6 works) · Psychiatry (5 works) · Environmental health (4 works) · Nursing (4 works) · Psychology (4 works) · Adolescent Sexual and Reproductive Health (3 works) · Biostatistics (3 works)