Elizabeth Spooner
Biographic Data
| ID | 7605555 |
|---|---|
| NAME | Elizabeth Spooner |
| GIVEN NAMES | Elizabeth |
| FAMILY NAME | Spooner |
| SIGNATURE | SPOONER E |
| AFFILIATIONS | South African Medical Research Council |
| ORCID | 0000-0002-1498-8131 |
| VERIFIED | Yes |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 6 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2019 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
Sars-CoV-2 seroprevalence among learners in grades 1–7, their parents and teachers in KwaZulu-Natal, South Africa
Introduction: There is limited information on SARS-CoV-2 seroprevalence among children and adolescents in LMIC school settings. We aimed to assess (1) the seroprevalence of SARS-CoV-2 antibodies, (2) prevalence of self-reported or confirmed SARS-CoV-2 prior infections and, (3) COVID-19 symptoms (including long-COVID) among a cohort of primary school learners, their parents and teachers in a semi-rural school setting approximately 3-years into the…
Group-based Self-Help Plus, Problem Management Plus and pre-exposure prophylaxis to improve mental health and reduce HIV risk in survivors of rape in KwaZulu-Natal, South Africa
Gender-based violence (GBV) and HIV are highly prevalent in South Africa and are significant public health problems. Rape is a risk factor for both HIV acquisition and adverse mental health outcomes. Post-rape interventions targeting HIV and mental health are needed to mitigate risk and aid recovery. Self-Help Plus (SH+) and Problem Management Plus (PM+) are lay counsellor-facilitated, group-based mental health interventions. We adapted them for …
Safety, effectiveness and immunogenicity of heterologous mRNA-1273 boost after prime with Ad26.COV2.S among healthcare workers in South Africa
Limited studies have been conducted on the safety and effectiveness of heterologous COVID-19 vaccine boosting in lower income settings, especially those with high-HIV prevalence., The Sisonke Heterologous mRNA-1273 boost after prime with Ad26.COV2.S (SHERPA) trial evaluated a mRNA-1273 boost after Ad26.COV2.S priming in South Africa. SHERPA was a single-arm, open-label, phase 3 study nested in the Sisonke implementation trial of 500000 healthcare…
Getting to under 1% vertical HIV transmission
We report here on the transmission of HIV in a cohort of breastfeeding infants enrolled in a prevention of mother to child HIV transmission (PMTCT) programme at the epicentre of the HIV pandemic. South Africa implemented option B+ for PMTCT in 2015. Between 2013 and 2018, we enrolled 1219 infants born to HIV positive women into a non-inferiority trial assessing the current cotrimoxazole prophylaxis guidelines for HIV-exposed uninfected infants. B…
Point-of-care CD4 testing
BACKGROUND: ) persists, and CD4 count testing is being overlooked since universal test-and-treat was implemented. Point-of-care CD4 testing could address this gap and assure differentiated care to these vulnerable patients with low CD4 counts. METHODS: A time randomised implementation trial was conducted, enrolling 603 HIV positive non-ART, not pregnant patients at a primary health care clinic in Durban, South Africa. Weeks were randomised to eit…
Point-of-care HIV testing best practice for early infant diagnosis
ISRCTN38911104 registered 9 January 2018 - retrospectively registered
No prominent works on this page.
Point-of-care HIV testing best practice for early infant diagnosis
ISRCTN38911104 registered 9 January 2018 - retrospectively registered
Getting to under 1% vertical HIV transmission
We report here on the transmission of HIV in a cohort of breastfeeding infants enrolled in a prevention of mother to child HIV transmission (PMTCT) programme at the epicentre of the HIV pandemic. South Africa implemented option B+ for PMTCT in 2015. Between 2013 and 2018, we enrolled 1219 infants born to HIV positive women into a non-inferiority trial assessing the current cotrimoxazole prophylaxis guidelines for HIV-exposed uninfected infants. B…
Point-of-care CD4 testing
BACKGROUND: ) persists, and CD4 count testing is being overlooked since universal test-and-treat was implemented. Point-of-care CD4 testing could address this gap and assure differentiated care to these vulnerable patients with low CD4 counts. METHODS: A time randomised implementation trial was conducted, enrolling 603 HIV positive non-ART, not pregnant patients at a primary health care clinic in Durban, South Africa. Weeks were randomised to eit…
Safety, effectiveness and immunogenicity of heterologous mRNA-1273 boost after prime with Ad26.COV2.S among healthcare workers in South Africa
Limited studies have been conducted on the safety and effectiveness of heterologous COVID-19 vaccine boosting in lower income settings, especially those with high-HIV prevalence., The Sisonke Heterologous mRNA-1273 boost after prime with Ad26.COV2.S (SHERPA) trial evaluated a mRNA-1273 boost after Ad26.COV2.S priming in South Africa. SHERPA was a single-arm, open-label, phase 3 study nested in the Sisonke implementation trial of 500000 healthcare…
Sars-CoV-2 seroprevalence among learners in grades 1–7, their parents and teachers in KwaZulu-Natal, South Africa
Introduction: There is limited information on SARS-CoV-2 seroprevalence among children and adolescents in LMIC school settings. We aimed to assess (1) the seroprevalence of SARS-CoV-2 antibodies, (2) prevalence of self-reported or confirmed SARS-CoV-2 prior infections and, (3) COVID-19 symptoms (including long-COVID) among a cohort of primary school learners, their parents and teachers in a semi-rural school setting approximately 3-years into the…
Group-based Self-Help Plus, Problem Management Plus and pre-exposure prophylaxis to improve mental health and reduce HIV risk in survivors of rape in KwaZulu-Natal, South Africa
Gender-based violence (GBV) and HIV are highly prevalent in South Africa and are significant public health problems. Rape is a risk factor for both HIV acquisition and adverse mental health outcomes. Post-rape interventions targeting HIV and mental health are needed to mitigate risk and aid recovery. Self-Help Plus (SH+) and Problem Management Plus (PM+) are lay counsellor-facilitated, group-based mental health interventions. We adapted them for …
Medicine (6 works) · Family medicine (4 works) · Immunology (4 works) · Environmental health (3 works) · HIV/AIDS Research and Interventions (3 works) · Internal Medicine (3 works) · Pediatrics (3 works) · Adolescent Sexual and Reproductive Health (2 works) · COVID-19 Clinical Research Studies (2 works) · Demography (2 works)