Willem J Kop
Biographic Data
| ID | 7636085 |
|---|---|
| NAME | Willem J Kop |
| GIVEN NAMES | Willem J |
| FAMILY NAME | Kop |
| SIGNATURE | KOP W J |
| AFFILIATIONS | Tilburg University |
| ORCID | 0000-0003-3141-4815 |
| VERIFIED | Yes |
| TOTAL WORKS | 35 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 35 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1994 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 0 |
Affective Responses to Acute Exercise: A Meta-Analysis of the Potential Beneficial Effects of a Single Bout of Exercise on General Mood, Anxiety, and Depressive Symptoms
OBJECTIVE: Acute exercise elicits various biobehavioral and psychological responses, but results are mixed with regard to the magnitude of exercise-induced affective reactions. This meta-analysis examines the magnitude of general mood state, anxiety, and depressive symptom responses to acute exercise while exploring exercise protocol characteristics and background health behaviors that may play a role in the affective response. METHODS: A total o…
Psychological Distress During Pregnancy and the Development of Pregnancy-Induced Hypertension: A Prospective Study
OBJECTIVE: Pregnancy-induced hypertension (PIH) is associated with serious complications in both the mother and the unborn child. We examined the possible association between trajectories of maternal psychological distress symptoms and PIH separately in primiparous and multiparous women. METHODS: Pregnancy-specific negative affect (P-NA) and depressive symptoms were assessed prospectively at each trimester using the Tilburg Pregnancy Distress Sca…
Facial Emotion Expression and the Inducibility of Myocardial Ischemia During Cardiac Stress Testing: The Role of Psychological Background Factors
OBJECTIVE: Negative emotional states, such as anger and anxiety, are associated with the onset of myocardial infarction and other acute clinical manifestations of ischemic heart disease. The likelihood of experiencing these short-term negative emotions has been associated with long-term psychological background factors such as depression, generalized anxiety, and personality factors. We examined the association of acute emotional states preceding…
Changes in Perceived Stress and Lifestyle Behaviors in Response to the Covid-19 Pandemic in The Netherlands: An Online Longitudinal Survey Study
The COVID-19 pandemic has substantial implications for physical and mental wellbeing. This study investigated changes, over time, in lifestyle behaviors and perceived stress during the initial phase of the pandemic and associations with COVID-19 symptoms, in the Dutch general population. An online longitudinal survey study was performed with pre-lockdown measurements in February, and subsequently in April and June 2020 (n = 259, mean age 59 ± 14 …
Complications and Healthcare Consumption of Pregnant Women with a Migrant Background: Could There be an Association with Psychological Distress
This cohort study found no differences in pregnancy-related complications, except for diabetes, nor different healthcare consumption, in women with a migrant background versus native Dutch, in a country with free health care access. However, women with a migrant background experienced more depressive symptoms, and when depressed their risk for hospital admission increased. Additional research is warranted to improve healthcare for this population
Individual Differences in Cross-System Physiological Activity at Rest and in Response to Acute Social Stress
OBJECTIVE: Individual differences in long-term cardiovascular disease risk are related to physiological responses to psychological stress. However, little is known about specific physiological response profiles in young adults that may set the stage for long-term increased cardiovascular disease risk. We investigated individual differences in profiles of resting cardiovascular physiology and stress reactivity, combining parasympathetic, sympathet…
Biopsychosocial Processes of Health and Disease During the Covid-19 Pandemic
The biopsychosocial model provides a useful perspective for understanding the development and characteristics of the COVID-19 pandemic and its anticipated long-term consequences for society as well as individuals. This article provides a biopsychosocial perspective on the COVID pandemic and an editorial comment on the articles in this Special Issue of Psychosomatic Medicine . Based on analysis of the PubMed database, it is shown that the attentio…
Personalized eHealth Program for Life-style Change: Results From the “Do Cardiac Health Advanced New Generated Ecosystem (Do CHANGE 2)” Randomized Controlled Trial
OBJECTIVE: Unhealthy life-style factors have adverse outcomes in cardiac patients. However, only a minority of patients succeed to change unhealthy habits. Personalization of interventions may result in critical improvements. The current randomized controlled trial provides a proof of concept of the personalized Do Cardiac Health Advanced New Generation Ecosystem (Do CHANGE) 2 intervention and evaluates effects on a) life-style and b) quality of …
Persistent Physical Symptoms as Perceptual Dysregulation: A Neuropsychobehavioral Model and Its Clinical Implications
OBJECTIVE: The mechanisms underlying the perception and experience of persistent physical symptoms are not well understood, and in the models, the specific relevance of peripheral input versus central processing, or of neurobiological versus psychosocial factors in general, is not clear. In this article, we proposed a model for this clinical phenomenon that is designed to be coherent with an underlying, relatively new model of the normal brain fu…
A European Research Agenda for Somatic Symptom Disorders, Bodily Distress Disorders, and Functional Disorders: Results of an Estimate-Talk-Estimate Delphi Expert Study
Background: Somatic Symptom Disorders (SSD), Bodily Distress Disorders (BDD) and functional disorders (FD) are associated with high medical and societal costs and pose a substantial challenge to the population and health policy of Europe. To meet this challenge, a specific research agenda is needed as one of the cornerstones of sustainable mental health research and health policy for SSD, BDD, and FD in Europe. Aim: To identify the main challenge…
Core Outcome Domains for Clinical Trials on Somatic Symptom Disorder, Bodily Distress Disorder, and Functional Somatic Syndromes: European Network on Somatic Symptom Disorders Recommendations
OBJECTIVE: The harmonization of core outcome domains in clinical trials facilitates comparison and pooling of data, and simplifies the preparation and review of research projects and comparison of risks and benefits of treatments. Therefore, we provide recommendations for the core outcome domains that should be considered in clinical trials on the efficacy and effectiveness of interventions for somatic symptom disorder, bodily distress disorder, …
Nitric Oxide Dysregulation in Patients With Heart Failure: The Association of Depressive Symptoms With L-Arginine, Asymmetric Dimethylarginine, Symmetric Dimethylarginine, and Isoprostane
Depressive symptoms were associated with markers of NO dysregulation, particularly the L-arginine/ADMA ratio and SDMA, in patients with HF. The lower L-arginine/ADMA ratio indicates less available NO, suggesting that NO-related endothelial dysfunction may play a role in the adverse risk of HF progression associated with depression
Evaluation of Duplicate Publications: An Article Retraction by The Journal of Pain
The editors of The Journal of Pain and Psychosomatic Medicine identified an incident of duplicate publication involving articles published in their respective journals. The Journal of Pain is retracting the following article: Costa-Martins JM, Pereira M, Martins H, Moura-Ramos M, Coelho R, Tavares J. Attachment styles, pain, and the consumption of analgesics during labor: a prospective observational study. J Pain 2014;15(3):304–11. The retraction…
The Editors Respond
Department of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands Department of Medicine, University of Minnesota, Minneapolis, Minnesota
Somatic Depressive Symptoms, Vital Exhaustion, and Fatigue: Divergent Validity of Overlapping Constructs
Department of Medical Psychology and Neuropsychology Center of Research on Psychology in Somatic diseases Tilburg University Tilburg, the Netherlands
Introducing a Special Series in Psychosomatic Medicine: Neuroscience in Health and Disease
Editor-in-Chief Department of Medical Psychology and Neurospychology Tilburg University Tilburg, The Netherlands
Divergent Effects of Joyful and Anxiety-Provoking Music on Endothelial Vasoreactivity
OBJECTIVE: To evaluate the extent to which music may affect endothelial function. In previous research, a link between music and physiologic parameters such as heart rate and blood pressure has been observed. METHODS: Randomized four-phase crossover and counterbalanced trial in ten healthy, nonsmoking volunteers (70% male; mean age, 35.6 years) that included self-selections of music evoking joy or provoking anxiety. Two additional phases included…
Autonomic Nervous System Dysfunction and Inflammation Contribute to the Increased Cardiovascular Mortality Risk Associated With Depression
OBJECTIVE: To investigate prospectively whether autonomic nervous system (ANS) dysfunction and inflammation play a role in the increased cardiovascular disease (CVD)-related mortality risk associated with depression. METHODS: Participants in the Cardiovascular Health Study (n = 907; mean age, 71.3 ± 4.6 years; 59.1% women) were evaluated for ANS indices derived from heart rate variability (HRV) analysis (frequency and time domain HRV, and nonline…
Association Between Symptoms of Depression and Anxiety With Heart Rate Variability in Patients With Implantable Cardioverter Defibrillators
OBJECTIVE: This study investigated whether depression and anxiety symptoms are associated with measures of autonomic nervous system dysfunction in patients with implantable cardioverter defibrillators who are at high risk of cardiac rhythm disturbances. Depression and anxiety are associated with autonomic nervous system dysfunction, which may promote the risk of malignant cardiac arrhythmias. METHODS: Patients with an implantable cardioverter def…
What’s in a Name? Psychosomatic Medicine and Biobehavioral Medicine
Freedland, Kenneth E. PhD; de Geus, Eco J.C. PhD; Golden, Robert N. MD; Kop, Willem J. PhD; Miller, Gregory E. PhD; Vaccarino, Viola MD, PhD; Brumback, Babette PhD; Llabre, Maria M. PhD; White, Victoria J. MA; Sheps, David S. MD, MSPH Author Information
Mental Stress-Induced Platelet Activation Among Patients With Coronary Artery Disease
Objective: To study patients with coronary artery disease (CAD) scheduled for coronary angioplasty and to examine platelet activation in response to mental stress as a potential mechanism involved in the association between psychosocial factors and cardiac outcomes. Psychosocial factors have been identified as risk factors for CAD and adverse cardiac outcomes, although the underlying mechanisms are poorly understood. Methods: Markers of platelet …
Mental Stress Hemodynamic Responses and Myocardial Ischemia: Does Left Ventricular Dysfunction Alter These Relationships
Objective: To assess if mental stress hemodynamic responses are impaired and related to mental stress (MS) ischemia in patients with left ventricular (LV) dysfunction. Background: Impaired LV function is an important coronary artery disease (CAD) risk factor and hemodynamic characteristics play an important role in clinical outcomes. Patients with severe LV dysfunction (SLVD) are frequently excluded from prior studies and the effects of LV dysfun…
Depressive Mood Symptoms and Fatigue After Exercise Withdrawal: The Potential Role of Decreased Fitness
OBJECTIVE: Depressive symptomatology is more prevalent among sedentary than physically active individuals. The present prospective study examines whether withdrawal of regular aerobic activity provokes depressive mood symptoms and fatigue, and to what extent reductions in fitness levels contribute to the development of these symptoms. METHODS: Forty participants (mean age of 31.3 +/- 7.5 years, 55% women) who exercised regularly (> or = 30 minute…
Social Network and Coronary Artery Calcification in Asymptomatic Individuals
BACKGROUND: Psychosocial factors are associated with the development of coronary artery disease. However, studies examining psychosocial factors as risk indicators for coronary artery calcification (CAC) have been inconclusive. METHODS: Seven hundred eighty-three participants (mean age 57.4 +/- 9.3 years, 47% female) underwent CAC imaging using electron beam tomography. Psychosocial measures included social network (number of people in the househ…
The Role of Immune System Parameters in the Relationship Between Depression and Coronary Artery Disease
The relationship between depressive symptoms and coronary artery disease (CAD) is mediated in part by immune system parameters. This review describes research on the psychoneuroimmunological pathways accounting for the association between depression and CAD, and addresses conceptual and methodological issues. Relationships between central nervous system correlates of depression and immune system parameters are bidirectional and are mediated via n…
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Vital exhaustion predicts new cardiac events after successful coronary angioplasty
Excessive tiredness is one of the most prevalent premonitory symptoms of myocardial infarction and sudden cardiac death. This state is labelled as vital exhaustion and consists of three components: fatigue, increased irritability, and demoralization. Vital exhaustion has been found to be an independent risk-indicator of myocardial infarction in one prospective study and several case-control studies. It is as yet unclear whether the association be…
Relationship of Blood Coagulation and Fibrinolysis to Vital Exhaustion
OBJECTIVE: Acute physical and psychological stressors affect blood coagulation and fibrinolysis, but little is known about hemostatic factors associated with chronic psychological stress. Prolonged psychological stress may end in a state of vital exhaustion, which has been shown to be a risk factor for first myocardial infarction and recurrent events after coronary angioplasty. The present study tested the hypothesis that vital exhaustion resulti…
Physical Activity and the Diurnal Pattern of Myocardial Ischemia in Patients With Coronary Artery Disease
Quigley, J. F.; Suchday, S.; Gottdiener, J. S.; Bairey-Merz, C.; Krantz, D. S.; Kop, W. J.; Patterson, S. M. Author Information
Mental Stress Testing in Patients With Implantable Cardioverter Defibrillators: Inducibility of T-Wave Alternans
s of Papers for 1999 Annual Meeting: Symposium: Psychosocial Factors in Malignant Cardiac Arrhythmias and Their Treatment with Implanted Defibrillators
Symposium Synopsis: Psychosocial Factors in Malignant Cardiac Arrhythmias and Their Treatment With Implanted Defibrillators (Icd)
s of Papers for 1999 Annual Meeting: Symposium: Psychosocial Factors in Malignant Cardiac Arrhythmias and Their Treatment with Implanted Defibrillators
Association Between Depression and Mortality in Older Adults: The Cardiovascular Health Study
Background Studies of the association between depressive symptoms and mortality in elderly populations have yielded contradictory findings. To address these discrepancies, we test this association using the most extensive array of sociodemographic and physical health control variables ever studied, to our knowledge, in a large population-based sample of elderly individuals. Objective To examine the relation between baseline depressive symptoms an…
The Nature of the Depressive Symptomatology Preceding Myocardial Infarction
Little is known about the nature of the depressive symptomatology preceding myocardial infarction (MI). Specification of the depressive symptomatology is important for the development of hypotheses about the biological mechanisms relating depressive symptoms to MI. To test the hypothesis that feelings of fatigue and loss of energy have the strongest predictive power of all depressive symptoms, the authors reanalyzed data from a prospective study …
Frailty in Older Adults: Evidence for a Phenotype
BACKGROUND: Frailty is considered highly prevalent in old age and to confer high risk for falls, disability, hospitalization, and mortality. Frailty has been considered synonymous with disability, comorbidity, and other characteristics, but it is recognized that it may have a biologic basis and be a distinct clinical syndrome. A standardized definition has not yet been established. METHODS: To develop and operationalize a phenotype of frailty in …
Diurnal Variations in Coagulation and Fibrinolysis in Vital Exhaustion
Objective Vital exhaustion (VE) predicts a first myocardial infarction (MI) and new cardiac events after a coronary angioplasty. To explore potential underlying pathophysiological mechanisms, we tested whether VE is associated with more pronounced diurnal variations in hemostasis. Methods Blood was drawn from 29 VE and 30 control males, all healthy and nonsmokers, to assess hemostatic measures at 7:00 AM and 6:00 PM. Results All measures of fibri…
Risk Factors for Myocardial Infarction During Vacation Travel
OBJECTIVES: Medical emergencies occur increasingly outside the usual health care area as a result of increased leisure and professional travel. Acute coronary syndromes are the leading cause of mortality during vacation. Vacation activities include physical and emotional triggers for myocardial infarction (MI). This study examines characteristics of vacation travel as risk factors for MI. METHODS: Patients diagnosed with MI during vacation abroad…
Social Network and Coronary Artery Calcification in Asymptomatic Individuals
BACKGROUND: Psychosocial factors are associated with the development of coronary artery disease. However, studies examining psychosocial factors as risk indicators for coronary artery calcification (CAC) have been inconclusive. METHODS: Seven hundred eighty-three participants (mean age 57.4 +/- 9.3 years, 47% female) underwent CAC imaging using electron beam tomography. Psychosocial measures included social network (number of people in the househ…
The Role of Immune System Parameters in the Relationship Between Depression and Coronary Artery Disease
The relationship between depressive symptoms and coronary artery disease (CAD) is mediated in part by immune system parameters. This review describes research on the psychoneuroimmunological pathways accounting for the association between depression and CAD, and addresses conceptual and methodological issues. Relationships between central nervous system correlates of depression and immune system parameters are bidirectional and are mediated via n…
Depressive Mood Symptoms and Fatigue After Exercise Withdrawal: The Potential Role of Decreased Fitness
OBJECTIVE: Depressive symptomatology is more prevalent among sedentary than physically active individuals. The present prospective study examines whether withdrawal of regular aerobic activity provokes depressive mood symptoms and fatigue, and to what extent reductions in fitness levels contribute to the development of these symptoms. METHODS: Forty participants (mean age of 31.3 +/- 7.5 years, 55% women) who exercised regularly (> or = 30 minute…
Mental Stress Hemodynamic Responses and Myocardial Ischemia: Does Left Ventricular Dysfunction Alter These Relationships
Objective: To assess if mental stress hemodynamic responses are impaired and related to mental stress (MS) ischemia in patients with left ventricular (LV) dysfunction. Background: Impaired LV function is an important coronary artery disease (CAD) risk factor and hemodynamic characteristics play an important role in clinical outcomes. Patients with severe LV dysfunction (SLVD) are frequently excluded from prior studies and the effects of LV dysfun…
Association Between Symptoms of Depression and Anxiety With Heart Rate Variability in Patients With Implantable Cardioverter Defibrillators
OBJECTIVE: This study investigated whether depression and anxiety symptoms are associated with measures of autonomic nervous system dysfunction in patients with implantable cardioverter defibrillators who are at high risk of cardiac rhythm disturbances. Depression and anxiety are associated with autonomic nervous system dysfunction, which may promote the risk of malignant cardiac arrhythmias. METHODS: Patients with an implantable cardioverter def…
What’s in a Name? Psychosomatic Medicine and Biobehavioral Medicine
Freedland, Kenneth E. PhD; de Geus, Eco J.C. PhD; Golden, Robert N. MD; Kop, Willem J. PhD; Miller, Gregory E. PhD; Vaccarino, Viola MD, PhD; Brumback, Babette PhD; Llabre, Maria M. PhD; White, Victoria J. MA; Sheps, David S. MD, MSPH Author Information
Mental Stress-Induced Platelet Activation Among Patients With Coronary Artery Disease
Objective: To study patients with coronary artery disease (CAD) scheduled for coronary angioplasty and to examine platelet activation in response to mental stress as a potential mechanism involved in the association between psychosocial factors and cardiac outcomes. Psychosocial factors have been identified as risk factors for CAD and adverse cardiac outcomes, although the underlying mechanisms are poorly understood. Methods: Markers of platelet …
Divergent Effects of Joyful and Anxiety-Provoking Music on Endothelial Vasoreactivity
OBJECTIVE: To evaluate the extent to which music may affect endothelial function. In previous research, a link between music and physiologic parameters such as heart rate and blood pressure has been observed. METHODS: Randomized four-phase crossover and counterbalanced trial in ten healthy, nonsmoking volunteers (70% male; mean age, 35.6 years) that included self-selections of music evoking joy or provoking anxiety. Two additional phases included…
Autonomic Nervous System Dysfunction and Inflammation Contribute to the Increased Cardiovascular Mortality Risk Associated With Depression
OBJECTIVE: To investigate prospectively whether autonomic nervous system (ANS) dysfunction and inflammation play a role in the increased cardiovascular disease (CVD)-related mortality risk associated with depression. METHODS: Participants in the Cardiovascular Health Study (n = 907; mean age, 71.3 ± 4.6 years; 59.1% women) were evaluated for ANS indices derived from heart rate variability (HRV) analysis (frequency and time domain HRV, and nonline…
Somatic Depressive Symptoms, Vital Exhaustion, and Fatigue: Divergent Validity of Overlapping Constructs
Department of Medical Psychology and Neuropsychology Center of Research on Psychology in Somatic diseases Tilburg University Tilburg, the Netherlands
Introducing a Special Series in Psychosomatic Medicine: Neuroscience in Health and Disease
Editor-in-Chief Department of Medical Psychology and Neurospychology Tilburg University Tilburg, The Netherlands
Nitric Oxide Dysregulation in Patients With Heart Failure: The Association of Depressive Symptoms With L-Arginine, Asymmetric Dimethylarginine, Symmetric Dimethylarginine, and Isoprostane
Depressive symptoms were associated with markers of NO dysregulation, particularly the L-arginine/ADMA ratio and SDMA, in patients with HF. The lower L-arginine/ADMA ratio indicates less available NO, suggesting that NO-related endothelial dysfunction may play a role in the adverse risk of HF progression associated with depression
Evaluation of Duplicate Publications: An Article Retraction by The Journal of Pain
The editors of The Journal of Pain and Psychosomatic Medicine identified an incident of duplicate publication involving articles published in their respective journals. The Journal of Pain is retracting the following article: Costa-Martins JM, Pereira M, Martins H, Moura-Ramos M, Coelho R, Tavares J. Attachment styles, pain, and the consumption of analgesics during labor: a prospective observational study. J Pain 2014;15(3):304–11. The retraction…
The Editors Respond
Department of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands Department of Medicine, University of Minnesota, Minneapolis, Minnesota
Core Outcome Domains for Clinical Trials on Somatic Symptom Disorder, Bodily Distress Disorder, and Functional Somatic Syndromes: European Network on Somatic Symptom Disorders Recommendations
OBJECTIVE: The harmonization of core outcome domains in clinical trials facilitates comparison and pooling of data, and simplifies the preparation and review of research projects and comparison of risks and benefits of treatments. Therefore, we provide recommendations for the core outcome domains that should be considered in clinical trials on the efficacy and effectiveness of interventions for somatic symptom disorder, bodily distress disorder, …
Medicine (32 works) · Internal Medicine (19 works) · Internal Medicine (18 works) · Psychology (17 works) · Psychiatry (15 works) · Cardiac Health and Mental Health (13 works) · Cardiology (11 works) · Clinical Psychology (9 works) · Depression (economics) (8 works) · Anxiety (7 works)