Alexandra Philipsen
Biographic Data
| ID | 7645321 |
|---|---|
| NAME | Alexandra Philipsen |
| GIVEN NAMES | Alexandra |
| FAMILY NAME | Philipsen |
| SIGNATURE | PHILIPSEN A |
| AFFILIATIONS | University of Bonn |
| ORCID | 0000-0001-6876-518X |
| VERIFIED | Yes |
| TOTAL WORKS | 14 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 13 |
| WORKS AS EDITOR | 1 |
| FIRST PUBLICATION YEAR | 2016 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Quantitative susceptibility mapping of brain iron in adult ADHD
In this adult sample, QSM provided no robust evidence for widespread or regionally specific alterations in brain iron susceptibility in ADHD after multiple-comparison correction. Nevertheless, the reproducible pattern of nominal effects-centered on ventral temporal and default-mode network hub regions-suggests that inter-individual variation in cortical susceptibility may relate to clinical heterogeneity and neurodevelopmental timing rather than …
Toxoplasma gondii affects trait anxiety in adult ADHD
Our data is the first revealing an association between T. gondii and trait anxiety in a serointensity-dependent manner in individuals with ADHD. Further research is needed to clarify the clinical impact of the observed lower trait anxiety in individuals with ADHD and latent T. gondii infection
Role of stimulus dose on neuropsychological functioning after electroconvulsive therapy in patients with major depressive disorder
ECT led to autobiographical memory impairment. The relationship between mean charge delivered and cognitive performance is heterogeneous across different cognitive domains and requires further research. Significant effects of the mean charge delivered were found without a significant difference in cognitive functioning compared to a healthy control group
Effects of a video game intervention on symptoms, training motivation, and visuo-spatial memory in depression
Besides a standalone cognitive training, the current findings suggest that cognitive trainings using a video game have potential to increase subjective well-being, show higher levels of training motivation, and lead to improvements in visuo-spatial (working) memory functions in MDD. However, given the mixed and unblinded nature of this study, the results should be interpreted with caution. Further research with larger samples and follow-up measur…
ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment
(1) Background: Attention deficit hyperactivity disorder (ADHD) is a common comorbid condition in opioid use disorder (OUD) and is associated with a more severe course of substance use. Patients with severe OUD who have not responded to oral opioid maintenance treatment can be treated with intravenous diamorphine up to three times per day. Here, we investigated the prevalence of ADHD among patients undergoing either daily diamorphine maintenance …
Computerspiel- und Internetsucht
Mit der Aufnahme in die ICD-11 hat die suchtartige Nutzung von Computerspielen als neues Störungsbild Eingang in die Gesundheitsversorgung gefunden. Auch andere Formen internetsüchtigen Verhaltens lassen sich nun, zumindest indirekt, als Diagnosen verschlüsseln. Die Ambulanz für Spielsucht Mainz weist eine langjährige Tradition in der Forschung und Behandlung von Verhaltenssüchten auf und ist führend in der Entwicklung von entsprechenden Interven…
Virtual reality induces symptoms of depersonalization and derealization
Trusting reports on internet forums, a substantial number of people have developed unpleasant symptoms of depersonalization (DP) and derealization (DR) after virtual reality (VR) consumption. Likewise, one case series study indicates that even after one single VR session, transient DPDR experiences may occur. Despite these indications, little is otherwise known about the risk of developing DPDR from VR consumption. Therefore, we carried out the p…
P300 Modulation via Transcranial Alternating Current Stimulation in Adult Attention-Deficit/Hyperactivity Disorder
Objective A repeated finding regarding event-related potentials (ERPs) is that patients with ADHD show a reduced P300 amplitude. This raises the question of whether the attention of ADHD patients can be increased by stabilizing the P300. Assuming that the P300 is generated by event-related oscillations (EROs) in the low frequency range (0–8 Hz), one approach to increase the P300 could be to stimulate the patient’s P300 underlying ERO by means of …
Disentangling ADHD's Presentation-Related Decision-Making—A Meta-Analytic Approach on Predominant Presentations
Background: Deficient decision-making (DM) in attention deficit/hyperactivity disorder (ADHD) is marked by altered reward sensitivity, higher risk taking, and aberrant reinforcement learning. Previous meta-analysis aggregate findings for the ADHD combined presentation (ADHD-C) mostly, while the ADHD predominantly inattentive presentation (ADHD-I) and the predominantly hyperactive/impulsive presentation (ADHD-H) were not disentangled. The objectiv…
The Senses of Agency and Ownership in Patients With Borderline Personality Disorder
Patients with borderline personality disorder (BPD) not only experience a strong instability in their affect and interpersonal relations but also disturbances in their self-experience, including dissociation and body-alienation symptoms. It is not yet understood whether an altered sense of ownership (SoO) or sense of agency (SoA) may contribute to these disturbances. One recent hypothesis is that patients with BPD have a reduced sense of self and…
Consumption of Synthetic Cannabinoids in Adult Attention-Deficit/Hyperactivity Disorder
Attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk for substance abuse and addiction. Synthetic cannabinoids (SC) have gained rising importance as their consumption increased rapidly in the last few years. However, SC consumption in patients with adult ADHD has not been investigated yet. A prospective clinical pilot study was conducted, including 60 adults with ADHD, assessing the prevalence of SC consumption and…
Acute Effects of Aerobic Exercise on Executive Function and Attention in Adult Patients With ADHD
Aerobic exercise can improve cognitive functions in healthy individuals and in various clinical groups, which might be particularly relevant for patients with ADHD. This study investigated the effects of a single bout of aerobic exercise on attention and executive functions in adult patients with ADHD, including functional MRI to examine the underlying neural mechanisms. On two different days, 23 adult patients with ADHD and 23 matched healthy co…
Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder
Increased cortical thickness in the left occipital cortex may represent a mechanism to compensate for dysfunctional attentional networks in male adult ADHD patients
Mindfulness-Based Cognitive Therapy and the Adult ADHD Brain
Attention-deficit/hyperactivity disorder (ADHD) is a recognized serious mental disorder that often persists into adulthood. The symptoms and impairments associated with ADHD often cause significant mental suffering in affected individuals. ADHD has been associated with abnormal neuronal activity in various neuronal circuits, such as the dorsofrontostriatal, orbitofrontostriatal, and frontocerebellar circuits. Psychopharmacological treatment with …
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Mindfulness-Based Cognitive Therapy and the Adult ADHD Brain
Attention-deficit/hyperactivity disorder (ADHD) is a recognized serious mental disorder that often persists into adulthood. The symptoms and impairments associated with ADHD often cause significant mental suffering in affected individuals. ADHD has been associated with abnormal neuronal activity in various neuronal circuits, such as the dorsofrontostriatal, orbitofrontostriatal, and frontocerebellar circuits. Psychopharmacological treatment with …
Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder
Increased cortical thickness in the left occipital cortex may represent a mechanism to compensate for dysfunctional attentional networks in male adult ADHD patients
Acute Effects of Aerobic Exercise on Executive Function and Attention in Adult Patients With ADHD
Aerobic exercise can improve cognitive functions in healthy individuals and in various clinical groups, which might be particularly relevant for patients with ADHD. This study investigated the effects of a single bout of aerobic exercise on attention and executive functions in adult patients with ADHD, including functional MRI to examine the underlying neural mechanisms. On two different days, 23 adult patients with ADHD and 23 matched healthy co…
The Senses of Agency and Ownership in Patients With Borderline Personality Disorder
Patients with borderline personality disorder (BPD) not only experience a strong instability in their affect and interpersonal relations but also disturbances in their self-experience, including dissociation and body-alienation symptoms. It is not yet understood whether an altered sense of ownership (SoO) or sense of agency (SoA) may contribute to these disturbances. One recent hypothesis is that patients with BPD have a reduced sense of self and…
Consumption of Synthetic Cannabinoids in Adult Attention-Deficit/Hyperactivity Disorder
Attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk for substance abuse and addiction. Synthetic cannabinoids (SC) have gained rising importance as their consumption increased rapidly in the last few years. However, SC consumption in patients with adult ADHD has not been investigated yet. A prospective clinical pilot study was conducted, including 60 adults with ADHD, assessing the prevalence of SC consumption and…
Disentangling ADHD's Presentation-Related Decision-Making—A Meta-Analytic Approach on Predominant Presentations
Background: Deficient decision-making (DM) in attention deficit/hyperactivity disorder (ADHD) is marked by altered reward sensitivity, higher risk taking, and aberrant reinforcement learning. Previous meta-analysis aggregate findings for the ADHD combined presentation (ADHD-C) mostly, while the ADHD predominantly inattentive presentation (ADHD-I) and the predominantly hyperactive/impulsive presentation (ADHD-H) were not disentangled. The objectiv…
Computerspiel- und Internetsucht
Mit der Aufnahme in die ICD-11 hat die suchtartige Nutzung von Computerspielen als neues Störungsbild Eingang in die Gesundheitsversorgung gefunden. Auch andere Formen internetsüchtigen Verhaltens lassen sich nun, zumindest indirekt, als Diagnosen verschlüsseln. Die Ambulanz für Spielsucht Mainz weist eine langjährige Tradition in der Forschung und Behandlung von Verhaltenssüchten auf und ist führend in der Entwicklung von entsprechenden Interven…
Virtual reality induces symptoms of depersonalization and derealization
Trusting reports on internet forums, a substantial number of people have developed unpleasant symptoms of depersonalization (DP) and derealization (DR) after virtual reality (VR) consumption. Likewise, one case series study indicates that even after one single VR session, transient DPDR experiences may occur. Despite these indications, little is otherwise known about the risk of developing DPDR from VR consumption. Therefore, we carried out the p…
P300 Modulation via Transcranial Alternating Current Stimulation in Adult Attention-Deficit/Hyperactivity Disorder
Objective A repeated finding regarding event-related potentials (ERPs) is that patients with ADHD show a reduced P300 amplitude. This raises the question of whether the attention of ADHD patients can be increased by stabilizing the P300. Assuming that the P300 is generated by event-related oscillations (EROs) in the low frequency range (0–8 Hz), one approach to increase the P300 could be to stimulate the patient’s P300 underlying ERO by means of …
Effects of a video game intervention on symptoms, training motivation, and visuo-spatial memory in depression
Besides a standalone cognitive training, the current findings suggest that cognitive trainings using a video game have potential to increase subjective well-being, show higher levels of training motivation, and lead to improvements in visuo-spatial (working) memory functions in MDD. However, given the mixed and unblinded nature of this study, the results should be interpreted with caution. Further research with larger samples and follow-up measur…
ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment
(1) Background: Attention deficit hyperactivity disorder (ADHD) is a common comorbid condition in opioid use disorder (OUD) and is associated with a more severe course of substance use. Patients with severe OUD who have not responded to oral opioid maintenance treatment can be treated with intravenous diamorphine up to three times per day. Here, we investigated the prevalence of ADHD among patients undergoing either daily diamorphine maintenance …
Role of stimulus dose on neuropsychological functioning after electroconvulsive therapy in patients with major depressive disorder
ECT led to autobiographical memory impairment. The relationship between mean charge delivered and cognitive performance is heterogeneous across different cognitive domains and requires further research. Significant effects of the mean charge delivered were found without a significant difference in cognitive functioning compared to a healthy control group
Quantitative susceptibility mapping of brain iron in adult ADHD
In this adult sample, QSM provided no robust evidence for widespread or regionally specific alterations in brain iron susceptibility in ADHD after multiple-comparison correction. Nevertheless, the reproducible pattern of nominal effects-centered on ventral temporal and default-mode network hub regions-suggests that inter-individual variation in cortical susceptibility may relate to clinical heterogeneity and neurodevelopmental timing rather than …
Toxoplasma gondii affects trait anxiety in adult ADHD
Our data is the first revealing an association between T. gondii and trait anxiety in a serointensity-dependent manner in individuals with ADHD. Further research is needed to clarify the clinical impact of the observed lower trait anxiety in individuals with ADHD and latent T. gondii infection
Psychology (10 works) · Attention Deficit Hyperactivity Disorder (9 works) · Clinical Psychology (8 works) · Medicine (8 works) · Psychiatry (8 works) · Clinical Psychology (7 works) · Cognition (5 works) · Neural and Behavioral Psychology Studies (5 works) · Audiology (4 works) · Functional Brain Connectivity Studies (4 works)