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Evelyne Heyer

Datos Biográficos

ID76486
NOMBREEvelyne Heyer
NOMBRESEvelyne
APELLIDOHeyer
FIRMAHEYER E
AFILIACIONESCentre National de la Recherche Scientifique
ORCID0000-0002-0266-3196
VERIFICADOSí
TOTAL DE OBRAS52
TOTAL DE CITAS123
TOTAL COMO AUTOR52
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN1990
AÑO MÁS RECIENTE DE PUBLICACIÓN2026
ÍNDICE H7
  • Genomic analyses of modern Central and Southeast Asian populations reveal the presence of multiple Denisovan populations

    Open Access•Charlotte Antoine-Derouet, Céline Bon et al.•ARTICLE•Cahiers du Centre de recherches…•2026

    Ce document a été généré automatiquement le

  • Investigation of admixture between Neanderthal, Denisova and Central and Southeast Asian Homo sapiens populations

    Open Access•Charlotte Antoine, Céline Bon et al.•ARTICLE•Cahiers du Centre de recherches…•2025

    Ce document a t gnr automatiquement le 16

  • Understanding genetic adaptation of Asian populations to their environment

    Open Access•Johanne Adam, J C Adams et al.•ARTICLE•Cahiers du Centre de recherches…•2025

    Ce document a t gnr automatiquement le 16 dcembre 2025. Le texte seul est utilisable

  • Investigation of admixture between Neanderthal, Denisova and Central and Southeast Asian populations

    Open Access•Charlotte Antoine, Céline Bon et al.•ARTICLE•Cahiers du Centre de recherches…•2024

    Ce document a t gnr automatiquement le 20 dcembre 2025. Le texte seul est utilisable

  • Les cycles économiques de la France

    Agnès Bénassy-Quéré, Antonin Aviat et al.•ARTICLE•Revue économique•2023•Referencias: 1

    Cet article propose une datation trimestrielle de référence des périodes de récession et d’expansion de l’économie française depuis 1970, réalisée par le comité de datation des cycles de l’Association française de science économique. La méthodologie repose sur deux piliers : 1) des estimations économétriques pour identifier les périodes candidates et 2) une approche narrative détaillant le contexte économique de l’époque pour finaliser la datatio…

  • BeDNA

    Open Access•Pauline Ehrhardt, Philippe Chambon et al.•ARTICLE•Cahiers du Centre de recherches…•2023•Citada por: 1•Referencias: 16

    La paléogénétique occupe désormais une place importante dans les problématiques archéologiques. Toutefois, les analyses d’ADN ancien peuvent être desservies, voire empêchées, par l’état de préservation des échantillons en raison de contamination par de l’ADN moderne ou de mauvaises conditions de stockage. Le projet beDNA, "banque d’échantillons et de Données Nationale Archéogénétique", souhaite donner les moyens d’analyses paléogénétiques futures…

  • Is the post-Neolithic Y chromosome bottleneck necessarily explained by violent competition between lineages

    Open Access•Léa Guyon, Jérémy Guez et al.•ARTICLE•Cahiers du Centre de recherches…•2023

    Most modern human populations are structured in lineages and/or clans (54%) and display unilineal descent rules, with individuals affiliated to the kinship group of their father (patrilineality, 40%) or of their mother (matrilineality, 14%) only. Moreover, residence rules – defining the place where a couple lives after marriage – such as patrilocality (64%) or matrilocality (20%), involving a differential migration of individuals between populati…

  • BeDNA

    Open Access•Pauline Ehrhardt, Philippe Chambon et al.•ARTICLE•Cahiers du Centre de recherches…•2023

    La paléogénétique s’intègre désormais couramment aux recherches archéologiques. Toutefois, la réussite des analyses d’ADN ancien dépend de la préservation initiale du matériel génétique dans les échantillons, et peuvent être entravées par la contamination par de l’ADN moderne ou par de mauvaises conditions de stockage du matériel. Le projet beDNA (banque d’échantillons et de Données Nationale Archéogénétique), développé par l’UMR 7206, se propose…

  • Us and them

    Open Access•Evelyne Heyer, Carole Reynaud‐paligot•ARTICLE•American Journal of Physical…•2021•Referencias: 18

    This paper present the content of the Musée de l'Homme exhibition “Us and them: from prejudice to racism” and provides a detailed explanation of how this content has been presented to the public. In a second section of this paper we explain some of the analysis and concepts, from a biological anthropology perspective, that were the foundation of the exhibition and provides some information about the current situation in France

  • Continuité génétique des populations anciennes et récentes d'Asie Centrale

    Open Access•Perle Guarino-Vignon, Perle Guarino‐vignon et al.•ARTICLE•Cahiers du Centre de recherches…•2021

    Depuis la préhistoire, l’Asie centrale méridionale est une région au carrefour des mouvements de populations, de cultures et de marchandises. Aujourd’hui l’Asie Centrale est peuplée par des populations réparties dans deux groupes culturels et linguistiques : le groupe Indo-iranien et le groupe Turco-mongol. L’établissement d’une base de données génétiques sur ces populations a permis d’étudier leur structure génétique en mettant en évidence la mi…

  • BeDNA

    Open Access•Pauline Ehrhardt, Philippe Chambon et al.•ARTICLE•Cahiers du Centre de recherches…•2021

    D’année en année, la paléogénétique prend toujours plus de place dans l’étude des populations humaines. Toutefois, les analyses d’ADN ancien peuvent être desservies par la préservation des échantillons, ou la contamination par de l’ADN moderne. L’hétérogénéité des méthodes de conservation des échantillons archéologiques, comme leur dispersion sur tout le territoire national, constituent des freins à ces analyses. Le projet beDNA (banque d’échanti…

  • La notion de race. Un regard actuel de la biologie et de la génétique

    Evelyne Heyer, Pierre-Henri Gouyon et al.•ARTICLE•Communications•2020

    La systématique est la science qui produit des systèmes permettant d'ordonner la biodiversité et de nommer les catégories ainsi produites. Ces catégories, familles, genres, espèces, races, etc., issues d'un processus de différenciation plus ou moins continu, sont, par nature, floues. Elles rendent compte imparfaitement d'une réalité : l'existence de lignées plus ou moins divergentes. Dans l'espèce humaine, comme dans toutes les autres, des différ…

  • Ancient human genomes from across the Eurasian steppes

    Open Access•Peter de Barros Damgaard, Nina Marchi et al.•ARTICLE•Nature•2018

  • Sex‐specific genetic diversity is shaped by cultural factors in Inner Asian human populations

    Open Access•Nina Marchi, Tatyana Hegay et al.•ARTICLE•American Journal of Physical…•2017•Citada por: 6•Referencias: 64

    OBJECTIVES: Sex-specific genetic structures have been previously documented worldwide in humans, even though causal factors have not always clearly been identified. In this study, we investigated the impact of ethnicity, geography and social organization on the sex-specific genetic structure in Inner Asia. Furthermore, we explored the process of ethnogenesis in multiple ethnic groups. METHODS: We sampled DNA in Central and Northern Asia from 39 p…

  • A Central Asian Language Survey

    Philippe Mennecier, John Nerbonne et al.•ARTICLE•Language Dynamics and Change•2016

    We have documented language varieties (either Turkic or Indo-European) spoken in 23 test sites by 88 informants belonging to the major ethnic groups of Kyrgyzstan, Tajikistan and Uzbekistan (Karakalpaks, Kazakhs, Kyrgyz, Tajiks, Uzbeks, Yaghnobis). The recorded linguistic material concerns 176 words of the extended Swadesh list and will be made publically available with the publication of this paper. Phonological diversity is measured by the Leve…

  • Comment la culture agit sur notre évolution

    Evelyne Heyer•ARTICLE•Sciences Humaines•2016

  • Genomic evidence for the Pleistocene and recent population history of Native Americans

    Open Access•Maanasa Raghavan, Matthias Steinrücken et al.•ARTICLE•Science•2015

    Genetic history of Native Americans Several theories have been put forth as to the origin and timing of when Native American ancestors entered the Americas. To clarify this controversy, Raghavan et al. examined the genomic variation among ancient and modern individuals from Asia and the Americas. There is no evidence for multiple waves of entry or recurrent gene flow with Asians in northern populations. The earliest migrations occurred no earlier…

  • Inference of sex‐specific expansion patterns in human populations from Y ‐chromosome polymorphism

    Open Access•Carla Aimé, Evelyne Heyer et al.•ARTICLE•American Journal of Physical…•2015

    Studying the current distribution of genetic diversity in humans has important implications for our understanding of the history of our species. We analyzed a set of linked STR and SNP loci from the paternally inherited Y chromosome to infer the past demography of 55 African and Eurasian populations, using both the parametric and nonparametric coalescent‐based methods implemented in the BEAST application. We inferred expansion events in most sede…

  • Patrilineal populations show more male transmission of reproductive success than cognatic populations in Central Asia, which reduces their genetic diversity

    Open Access•Evelyne Heyer, Jean‐Tristan Brandenburg et al.•ARTICLE•American Journal of Physical…•2015•Citada por: 2•Referencias: 43

    OBJECTIVE: The extent to which social organization of human societies impacts the patterns of genetic diversity remains an open question. Here, we investigate the transmission of reproductive success in patrilineal and cognatic populations from Central Asia using a coalescent approach. METHODS: We performed a study on the mitochondrial DNA (mtDNA) and Y chromosome polymorphism of patrilineal and cognatic populations from Central Asia. We reconstr…

  • Lactase Persistence Variants in Arabia and in the African Arabs

    Edita Priehodová, Edita Priehodová Edita Priehodová et al.•ARTICLE•Human Biology•2014•Citada por: 7•Referencias: 9

    Lactase persistence (LP), the state enabling the digestion of milk sugar in adulthood, occurs only in some human populations. The convergent and independent origin of this physiological ability in Europe and Africa is linked with animal domestication that either had started in both places independently or had spread from the Near East by acculturation. However, it has recently been shown that at least in its southern parts, the population of Arab…

  • Genetic Diversity of Four Filipino Negrito Populations from Luzon

    Evelyne Heyer, E Heyer E Heyer et al.•ARTICLE•Human Biology•2013•Citada por: 11•Referencias: 33

    Genetic data corresponding to four negrito populations (two Aeta and two Agta; n = 120) from the Luzon region of the Philippines have been analyzed. These data comprise mitochondrial DNA (mtDNA) hypervariable segment 1 haplotypes and haplogroups, Y-chromosome haplogroups and short tandem repeats (STRs), autosomal STRs, and X-chromosome STRs. The genetic diversity and structure of the populations were investigated at a local, regional, and interre…

  • Short stature in African pygmies is not explained by sexual selection

    Open Access•Noémie S A Becker, Noémie S Becker et al.•ARTICLE•Evolution and Human Behavior•2012

  • Interview with Laura Fortunato, Winner of the 2011 Gabriel W. Lasker Prize

    Evelyne Heyer•ARTICLE•Human Biology•2012•Referencias: 20

    Fellow at the Santa Fe Institute in Santa Fe

  • Dans l’épaisseur du temps

    Open Access•P Antoine, Patrick Auguste et al.•BOOK•Dans l’épaisseur du temps•2011

    C’est autour de l’année 1859 que la préhistoire s’affirme, à l’échelle de l’Europe, comme un domaine de recherche nouveau et fécond. Les grandes disciplines des sciences naturelles (géologie, paléontologie...) et des sciences de l’homme (archéologie, histoire, philologie...) participent à la création de cette nouvelle science à travers les débats fondateurs portant sur l’ancienneté de l’homme et sur son origine animale. En une décennie, c’est tou…

  • Indirect evidence for the genetic determination of short stature in African Pygmies

    Open Access•Noémie S A Becker, Noémie S Becker et al.•ARTICLE•American Journal of Physical…•2011•Citada por: 13•Referencias: 51

    Central African Pygmy populations are known to be the shortest human populations worldwide. Many evolutionary hypotheses have been proposed to explain this short stature: adaptation to food limitations, climate, forest density, or high mortality rates. However, such hypotheses are difficult to test given the lack of long‐term surveys and demographic data. Whether the short stature observed nowadays in African Pygmy populations as compared to thei…

Siguiente
  • Geographic Patterns of (Genetic, Morphologic, Linguistic) Variation

    Franz Manni, Etienne Guerard et al.•ARTICLE•Human Biology•2004•Citada por: 18•Referencias: 3

    When sampling locations are known, the association between genetic and geographic distances can be tested by spatial autocorrelation or regression methods. These tests give some clues to the possible shape of the genetic landscape. Nevertheless, correlation analyses fail when attempting to identify where genetic barriers exist, namely, the areas where a given variable shows an abrupt rate of change. To this end, a computational geometry approach …

  • Y-Chromosome Analysis in Egypt Suggests a Genetic Regional Continuity in Northeastern Africa

    Franz Manni, Pascal Leonardi et al.•ARTICLE•Human Biology•2002•Citada por: 14•Referencias: 2

    The geographic location of Egypt, at the interface between North Africa, the Middle East, and southern Europe, prompted us to investigate the genetic diversity of this population and its relationship with neighboring populations. To assess the extent to which the modern Egyptian population reflects this intermediate geographic position, ten Unique Event Polymorphisms (UEPs), mapping to the nonrecombining portion of the Y chromosome, have been typ…

  • Indirect evidence for the genetic determination of short stature in African Pygmies

    Open Access•Noémie S A Becker, Noémie S Becker et al.•ARTICLE•American Journal of Physical…•2011•Citada por: 13•Referencias: 51

    Central African Pygmy populations are known to be the shortest human populations worldwide. Many evolutionary hypotheses have been proposed to explain this short stature: adaptation to food limitations, climate, forest density, or high mortality rates. However, such hypotheses are difficult to test given the lack of long‐term surveys and demographic data. Whether the short stature observed nowadays in African Pygmy populations as compared to thei…

  • Lactase Persistence in Central Asia

    Evelyne Heyer, Lionel Brazier et al.•ARTICLE•Human Biology•2011•Citada por: 13•Referencias: 38

    The aim of the present study is to document the evolution of the lactase persistence trait in Central Asia, a geographical area that is thought to have been a region of long-term pastoralism. Several ethnic groups co-exist in this area: Indo-Iranian speakers who are traditionally agriculturist (Tajik) and Turkic speakers who used to be nomadic herders (Kazakh, Karakalpak, Kyrgyz, Turkmen). It was recently demonstrated that horse milking practice …

  • Genetic Diversity of Four Filipino Negrito Populations from Luzon

    Evelyne Heyer, E Heyer E Heyer et al.•ARTICLE•Human Biology•2013•Citada por: 11•Referencias: 33

    Genetic data corresponding to four negrito populations (two Aeta and two Agta; n = 120) from the Luzon region of the Philippines have been analyzed. These data comprise mitochondrial DNA (mtDNA) hypervariable segment 1 haplotypes and haplogroups, Y-chromosome haplogroups and short tandem repeats (STRs), autosomal STRs, and X-chromosome STRs. The genetic diversity and structure of the populations were investigated at a local, regional, and interre…

  • Lactase Persistence Variants in Arabia and in the African Arabs

    Edita Priehodová, Edita Priehodová Edita Priehodová et al.•ARTICLE•Human Biology•2014•Citada por: 7•Referencias: 9

    Lactase persistence (LP), the state enabling the digestion of milk sugar in adulthood, occurs only in some human populations. The convergent and independent origin of this physiological ability in Europe and Africa is linked with animal domestication that either had started in both places independently or had spread from the Near East by acculturation. However, it has recently been shown that at least in its southern parts, the population of Arab…

  • Genetic traces of east‐to‐west human expansion waves in Eurasia

    Open Access•Raphaëlle Chaix, Frédéric Austerlitz et al.•ARTICLE•American Journal of Physical…•2008•Citada por: 7•Referencias: 40

    In this study, we describe the landscape of human demographic expansions in Eurasia using a large continental Y chromosome and mitochondrial DNA dataset. Variation at these two uniparentally‐inherited genetic systems retraces expansions that occurred in the past 60 ky, and shows a clear decrease of expansion ages from east to west Eurasia. To investigate the demographic events at the origin of this westward decrease of expansion ages, the estimat…

  • Sex‐specific genetic diversity is shaped by cultural factors in Inner Asian human populations

    Open Access•Nina Marchi, Tatyana Hegay et al.•ARTICLE•American Journal of Physical…•2017•Citada por: 6•Referencias: 64

    OBJECTIVES: Sex-specific genetic structures have been previously documented worldwide in humans, even though causal factors have not always clearly been identified. In this study, we investigated the impact of ethnicity, geography and social organization on the sex-specific genetic structure in Inner Asia. Furthermore, we explored the process of ethnogenesis in multiple ethnic groups. METHODS: We sampled DNA in Central and Northern Asia from 39 p…

  • New method for surname studies of ancient patrilineal population structures, and possible application to improvement of Y‐chromosome sampling

    Open Access•Franz Manni, Bruno Toupance et al.•ARTICLE•American Journal of Physical…•2005•Citada por: 6•Referencias: 24

    Several studies showed that surnames are good markers to infer patrilineal genetic structures of populations, both on regional and microregional scales. As a case study, the spatial patterns of the 9,929 most common surnames of the Netherlands were analyzed by a clustering method called self‐organizing maps (SOMs). The resulting clusters grouped surnames with a similar geographic distribution and origin. The analysis was shown to be in agreement …

  • Les probabilités de transmission des gènes fondateurs dans cinq populations régionales du Québec

    Open Access•Marc Tremblay, Marc Adélard Tremblay et al.•ARTICLE•Population•2003•Citada por: 4•Referencias: 12

    Certaines maladies héréditaires rares ont une incidence anormalement élevée dans la population québécoise. Les gènes délétères associés à ces maladies ont été vraisemblablement introduits au XVII e siècle par des immigrants dont les descendants sont les ancêtres d'une grande partie de la population contemporaine du Québec. L'objectif de cette étude est de mesurer la transmission différentielle des gènes de fondateurs qui sont à l'origine de cinq …

  • "Les "enfants utiles

    Open Access•Evelyne Heyer, Marie-Hélène Cazes•ARTICLE•Population•1999•Citada por: 4

    Heyer É., Cazes M.-H. Les «enfants utiles» : une mesure démographique pour la génétique des populations. In: Population, 54e année, n°4-5, 1999. pp. 677-691

  • La consanguinité, révélateur de la structure de la population. L'exemple de la vallée de la Valserine du XVIIIe siècle à nos jours

    Open Access•Alain Bideau, Guy Brunet et al.•ARTICLE•Population•1994•Citada por: 4

    Bideau (Alain), Brunet (Guy), Heyer (Evelyne), Plauchu (Henri). - La consanguinité, révélateur de la structure de la population. L'exemple de la vallée de la Valse- rine du XVIIIe siècle à nos jours Les démographes-historiens établissent généralement un taux de mariages consanguins grâce aux déclarations de dispense dans les actes de mariage. La confrontation de ces déclarations avec d'autres sources (registre de l'Évêché et corpus généalogique) …

  • One Founder/One Gene Hypothesis in a New Expanding Population

    Evelyne Heyer•ARTICLE•Human Biology•2009•Citada por: 3

    High frequencies of some rare inherited recessive disorders can be found in the Saguenay region of Quebec, Canada. Four disorders have a carrier frequency of about 0.04 (in the range 0.035-0.05): pseudovitamin D-dependent rickets, hereditary tyrosinemia type 1, Charlevoix-Saguenay spastic ataxia, and sensorimotor polyneuropathy with or without agenesis of the corpus callosum. Molecular data suggest that only 1 mutation has been introduced into th…

  • Senescence of reproduction may explain adaptive menopause in humans

    Open Access•Samuel Pavard, C Jessica E Metcalf et al.•ARTICLE•American Journal of Physical…•2008•Citada por: 3•Referencias: 47

    The “mother” hypothesis is one of the main adaptive explanations of human menopause. It postulates that reproductive cessation constitutes a strategy that has been selected for during human evolution because mothers at older ages might maximize their fitness by investing resources in the survival and reproduction of their living children rather than by continuing to reproduce. This study provides a test of this hypothesis. Fertility functions tha…

  • Genetic consequences of differential demographic behaviour in the Saguenay region, Québec

    Open Access•Evelyne Heyer•ARTICLE•American Journal of Physical…•1995•Citada por: 3•Referencias: 13

    Some rare inherited disorders are found with a high frequency in the population of the Saguenay region (Québec province, Canada, population 300,000). Inbreeding coefficients are too low to be an explanation for these high frequencies. In the first decades of settlement (1842–1870), most of the immigrants came from a small region called Charlevoix (east of Québec city). As most of the genetic disorders found in the Saguenay region are also found i…

  • Patrilineal populations show more male transmission of reproductive success than cognatic populations in Central Asia, which reduces their genetic diversity

    Open Access•Evelyne Heyer, Jean‐Tristan Brandenburg et al.•ARTICLE•American Journal of Physical…•2015•Citada por: 2•Referencias: 43

    OBJECTIVE: The extent to which social organization of human societies impacts the patterns of genetic diversity remains an open question. Here, we investigate the transmission of reproductive success in patrilineal and cognatic populations from Central Asia using a coalescent approach. METHODS: We performed a study on the mitochondrial DNA (mtDNA) and Y chromosome polymorphism of patrilineal and cognatic populations from Central Asia. We reconstr…

  • Transmission of migration propensity increases genetic divergence between populations

    Open Access•Alain Gagnon, Bruno Toupance et al.•ARTICLE•American Journal of Physical…•2006•Citada por: 2•Referencias: 30

    The advent of molecular genetics has brought invaluable information, which is now routinely used by anthropologists in their attempt to reconstruct our demographic past. Since mitochondrial DNA loci are much more similar between populations than are Y‐chromosome loci, it is suggested that women had a much higher migration rate than men throughout history. Based on an examination of intergenerational migration patterns in three large demographic d…

  • BeDNA

    Open Access•Pauline Ehrhardt, Philippe Chambon et al.•ARTICLE•Cahiers du Centre de recherches…•2023•Citada por: 1•Referencias: 16

    La paléogénétique occupe désormais une place importante dans les problématiques archéologiques. Toutefois, les analyses d’ADN ancien peuvent être desservies, voire empêchées, par l’état de préservation des échantillons en raison de contamination par de l’ADN moderne ou de mauvaises conditions de stockage. Le projet beDNA, "banque d’échantillons et de Données Nationale Archéogénétique", souhaite donner les moyens d’analyses paléogénétiques futures…

  • A Y-chromosome portrait of the population of Jerba (Tunisia) to elucidate its complex demographic history

    Open Access•Franz Manni, Pascal Leonardi et al.•ARTICLE•Cahiers du Centre de recherches…•2005•Citada por: 1•Referencias: 34

    L’histoire démographique de l’île de Jerba est très ancienne en raison de sa position centrale dans le bassin de la mer Méditerranée, c’est la raison pour laquelle plusieurs populations se sont succédées sur l’île dont la population est, de nos jours, hétérogène (Arabes, Berbères, Noirs, Juifs). Afin d’étudier la variabilité du chromosome Y de la population de Jerba nous avons analysé 10 polymorphismes, SRY-2627 ; SRY-10831a ; SRY-4064 ; 92R7 ; T…

  • The Transmission Probabilities of Founder Genes in Five Regional Populations of Quebec

    Open Access•Marc Adélard Tremblay, Julie Arsenault et al.•ARTICLE•Population (English Edition•2003•Citada por: 1•Referencias: 1

  • "Sygap". Un logiciel de gestion et d'analyse de population

    S Poulard, Evelyne Heyer et al.•ARTICLE•Annales de Démographie Historique•1990

    Le PRDH de l'Université de Montréal et le Groupe de recherche sur la maladie de Rendu-Osier (Lyon) ont développé en commun un logiciel de gestion et d'analyse de registres de population. Conçu pour systèmes IBM, il est structuré à partir du logiciel dBase III et ne nécessite que peu d'espace pour fonctionner (2,8 Mo pour 8 500 individus). Le coeur du logiciel permet de gérer le registre, en consultant ou modifiant les données, en retranchant ou a…

  • Intervals between marriage and first birth in mothers and daughters

    Open Access•Bertrand Desjardins, Alain Bideau et al.•ARTICLE•Journal of Biosocial Science•1991

    Marriage-first birth intervals are examined in two historical populations, Quebec (1608–1765) and Haut-Jura (1689–1980), comparing intervals in mothers and daughters, and in sister-sister pairs. The results point to a weak relationship between intervals of mothers and daughters, though it does not attain significance. Shared environment does not seem to be responsible since there is no association between pairs of sisters from the same population…

  • An abnormal concentration of cases of Rendu-Osler disease in the Valserine valley of the French Jura

    Open Access•Alain Bideau, G Brunet et al.•ARTICLE•Annals of Human Biology•1992

    An important concentration of patients with Rendu-Osler disease occurs in the Valserine valley of the French Jura. A study of marriages shows that, in spite of its somewhat remote location, the valley cannot be considered an isolate, but that, on the contrary, exogamy is widely practised. Only 17.8% of the genes of inhabitants during the present century can be traced to the original population, but persons affected with the disease belong to a su…

  • Population structure and immigration; a study of the Valserine Valley (French Jura) from the 17th century until the present

    Open Access•Evelyne Heyer•ARTICLE•Annals of Human Biology•1993

    The establishment of the genealogies and biographies of inhabitants of selected villages from the Haut-Jura from the 17th century up to the present day has enabled us to demonstrate the major role of immigration on the genetic structure of a population. The evaluation of the effective descendance of native versus immigrant couples shows the imbalance of demographic contribution in favour of the first category. Immigrant couples account for 26% of…

  • La consanguinité, révélateur de la structure de la population. L'exemple de la vallée de la Valserine du XVIIIe siècle à nos jours

    Open Access•Alain Bideau, Guy Brunet et al.•ARTICLE•Population•1994•Citada por: 4

    Bideau (Alain), Brunet (Guy), Heyer (Evelyne), Plauchu (Henri). - La consanguinité, révélateur de la structure de la population. L'exemple de la vallée de la Valse- rine du XVIIIe siècle à nos jours Les démographes-historiens établissent généralement un taux de mariages consanguins grâce aux déclarations de dispense dans les actes de mariage. La confrontation de ces déclarations avec d'autres sources (registre de l'Évêché et corpus généalogique) …

  • Genetic consequences of differential demographic behaviour in the Saguenay region, Québec

    Open Access•Evelyne Heyer•ARTICLE•American Journal of Physical…•1995•Citada por: 3•Referencias: 13

    Some rare inherited disorders are found with a high frequency in the population of the Saguenay region (Québec province, Canada, population 300,000). Inbreeding coefficients are too low to be an explanation for these high frequencies. In the first decades of settlement (1842–1870), most of the immigrants came from a small region called Charlevoix (east of Québec city). As most of the genetic disorders found in the Saguenay region are also found i…

  • D'une génération à l'autre

    Marc Tremblay, Marc Adélard Tremblay et al.•ARTICLE•Annales de Démographie Historique•1999

    La comparaison des comportements démographiques entre générations successives (parents-enfants) requiert habituellement des données qui s'étalent sur une longue période. L'utilisation d'un fichier de population permet d'effectuer ce type de comparaisons intergénérationnelles. À l'aide du fichier BALSAC, qui reconstitue la population de la région du Saguenay (Québec, Canada) depuis ses origines (milieu du XIXe siècle), nous voulons vérifier s'il e…

  • "Les "enfants utiles

    Open Access•Evelyne Heyer, Marie-Hélène Cazes•ARTICLE•Population•1999•Citada por: 4

    Heyer É., Cazes M.-H. Les «enfants utiles» : une mesure démographique pour la génétique des populations. In: Population, 54e année, n°4-5, 1999. pp. 677-691

  • Les «enfants utiles

    Open Access•Marie-Hélène Cazes, Evelyne Heyer•ARTICLE•Population•1999

    Heyer Evelyne, Cazes Marie-Hélène.- Les «enfants utiles» : une mesure démographique pour la génétique des populations En démographie historique, on définit la contribution d'un individu à la population de la génération suivante par son nombre d'enfants. Cependant seuls ceux de ces enfants qui procréeront à leur tour seront « utiles » pour le généticien des populations, au sens où ils transmettront des gènes à la génération suivante. Cet article s…

  • Intergenerational correlation of effective family size in early Québec (Canada)

    Alain Gagnon, Evelyne Heyer•ARTICLE•American Journal of Human Biology•2001

    The use of a comprehensive demographic database of the early French Canadian population (1608–1800) reveals an almost null impact of parents' fertility on children's fertility (r ≃ 0.01–0.05), which contradicts the commonly held view that family size has a tendency to run in families. However, in this population, there is a clear transmission from one generation to the next of the effective family size within a given geographical area (EFS, defin…

  • Intergenerational correlation of effective family size in early Québec (Canada)

    Open Access•Alain Gagnon, Evelyne Heyer•ARTICLE•American Journal of Human Biology•2001

    The use of a comprehensive demographic database of the early French Canadian population (1608–1800) reveals an almost null impact of parents' fertility on children's fertility ( r ≃ 0.01–0.05), which contradicts the commonly held view that family size has a tendency to run in families. However, in this population, there is a clear transmission from one generation to the next of the effective family size within a given geographical area (EFS, defi…

  • Fragmentation of the Qu bec population genetic pool (Canada)

    Open Access•Alain Gagnon, Evelyne Heyer•ARTICLE•American Journal of Physical…•2001•Referencias: 8

    The 6 million French-Canadians of Québec derive from a relatively small number of founders. Consequently, some hereditary diseases, which may or may not present a worldwide distribution, have been detected in high frequency in this population. Several studies, however, indicate a nonuniform distribution of these diseases through the population, suggesting that the French-Canadian founder effect has been geographically stratified. Here we explore …

  • Y-Chromosome Analysis in Egypt Suggests a Genetic Regional Continuity in Northeastern Africa

    Franz Manni, Pascal Leonardi et al.•ARTICLE•Human Biology•2002•Citada por: 14•Referencias: 2

    The geographic location of Egypt, at the interface between North Africa, the Middle East, and southern Europe, prompted us to investigate the genetic diversity of this population and its relationship with neighboring populations. To assess the extent to which the modern Egyptian population reflects this intermediate geographic position, ten Unique Event Polymorphisms (UEPs), mapping to the nonrecombining portion of the Y chromosome, have been typ…

  • The Transmission Probabilities of Founder Genes in Five Regional Populations of Quebec

    Open Access•Marc Adélard Tremblay, Julie Arsenault et al.•ARTICLE•Population (English Edition•2003•Citada por: 1•Referencias: 1

  • The Transmission Probabilities of Founder Genes in Five Regional Populations of Quebec

    Open Access•Marc Adélard Tremblay, Julie Arsenault et al.•ARTICLE•Population (English Edition•2003•Referencias: 2

    Certaines maladies héréditaires rares ont une incidence anormalement élevée dans la population québécoise. Les gènes délétères associés à ces maladies ont été vraisemblablement introduits au XVIIe siècle par des immigrants dont les descendants sont les ancêtres d’une grande partie de la population contemporaine du Québec. L’objectif de cette étude est de mesurer la transmission différentielle des gènes de fondateurs qui sont à l’origine de cinq p…

  • Les probabilités de transmission des gènes fondateurs dans cinq populations régionales du Québec

    Open Access•Marc Tremblay, Marc Adélard Tremblay et al.•ARTICLE•Population•2003•Citada por: 4•Referencias: 12

    Certaines maladies héréditaires rares ont une incidence anormalement élevée dans la population québécoise. Les gènes délétères associés à ces maladies ont été vraisemblablement introduits au XVII e siècle par des immigrants dont les descendants sont les ancêtres d'une grande partie de la population contemporaine du Québec. L'objectif de cette étude est de mesurer la transmission différentielle des gènes de fondateurs qui sont à l'origine de cinq …

  • Geographic Patterns of (Genetic, Morphologic, Linguistic) Variation

    Franz Manni, Etienne Guerard et al.•ARTICLE•Human Biology•2004•Citada por: 18•Referencias: 3

    When sampling locations are known, the association between genetic and geographic distances can be tested by spatial autocorrelation or regression methods. These tests give some clues to the possible shape of the genetic landscape. Nevertheless, correlation analyses fail when attempting to identify where genetic barriers exist, namely, the areas where a given variable shows an abrupt rate of change. To this end, a computational geometry approach …

  • Mother’s Death and Child Survival

    Open Access•Samuel Pavard, Alain Gagnon et al.•ARTICLE•Journal of Biosocial Science•2005

    The aim of this paper is to account for the effect of mother's death on child survival in a historical population. Using comprehensive data on the early French Canadian population of Quebec, evidence is provided for a higher risk of dying for motherless children that remains significant over all childhood and long after the death of the mother. The specific effect of the loss of maternal care was estimated by comparing mortality before and after …

  • New method for surname studies of ancient patrilineal population structures, and possible application to improvement of Y‐chromosome sampling

    Open Access•Franz Manni, Bruno Toupance et al.•ARTICLE•American Journal of Physical…•2005•Citada por: 6•Referencias: 24

    Several studies showed that surnames are good markers to infer patrilineal genetic structures of populations, both on regional and microregional scales. As a case study, the spatial patterns of the 9,929 most common surnames of the Netherlands were analyzed by a clustering method called self‐organizing maps (SOMs). The resulting clusters grouped surnames with a similar geographic distribution and origin. The analysis was shown to be in agreement …

  • A Y-chromosome portrait of the population of Jerba (Tunisia) to elucidate its complex demographic history

    Open Access•Franz Manni, Pascal Leonardi et al.•ARTICLE•Cahiers du Centre de recherches…•2005•Citada por: 1•Referencias: 34

    L’histoire démographique de l’île de Jerba est très ancienne en raison de sa position centrale dans le bassin de la mer Méditerranée, c’est la raison pour laquelle plusieurs populations se sont succédées sur l’île dont la population est, de nos jours, hétérogène (Arabes, Berbères, Noirs, Juifs). Afin d’étudier la variabilité du chromosome Y de la population de Jerba nous avons analysé 10 polymorphismes, SRY-2627 ; SRY-10831a ; SRY-4064 ; 92R7 ; T…

  • Transmission of migration propensity increases genetic divergence between populations

    Open Access•Alain Gagnon, Bruno Toupance et al.•ARTICLE•American Journal of Physical…•2006•Citada por: 2•Referencias: 30

    The advent of molecular genetics has brought invaluable information, which is now routinely used by anthropologists in their attempt to reconstruct our demographic past. Since mitochondrial DNA loci are much more similar between populations than are Y‐chromosome loci, it is suggested that women had a much higher migration rate than men throughout history. Based on an examination of intergenerational migration patterns in three large demographic d…

  • Senescence of reproduction may explain adaptive menopause in humans

    Open Access•Samuel Pavard, C Jessica E Metcalf et al.•ARTICLE•American Journal of Physical…•2008•Citada por: 3•Referencias: 47

    The “mother” hypothesis is one of the main adaptive explanations of human menopause. It postulates that reproductive cessation constitutes a strategy that has been selected for during human evolution because mothers at older ages might maximize their fitness by investing resources in the survival and reproduction of their living children rather than by continuing to reproduce. This study provides a test of this hypothesis. Fertility functions tha…

  • Genetic traces of east‐to‐west human expansion waves in Eurasia

    Open Access•Raphaëlle Chaix, Frédéric Austerlitz et al.•ARTICLE•American Journal of Physical…•2008•Citada por: 7•Referencias: 40

    In this study, we describe the landscape of human demographic expansions in Eurasia using a large continental Y chromosome and mitochondrial DNA dataset. Variation at these two uniparentally‐inherited genetic systems retraces expansions that occurred in the past 60 ky, and shows a clear decrease of expansion ages from east to west Eurasia. To investigate the demographic events at the origin of this westward decrease of expansion ages, the estimat…

  • Update to Heyer's “One Founder/One Gene Hypothesis in a New Expanding Population” (1999)

    Evelyne Heyer, Frédéric Austerlitz•ARTICLE•Human Biology•2009

    International audience

  • Update to Heyer's "One Founder/One Gene Hypothesis in a New Expanding Population" (1999)

    Evelyne Heyer, Frédéric Austerlitz•ARTICLE•Human Biology•2009

    Update to Heyer's "One Founder/One Gene Hypothesis in a New Expanding Population" (1999) Evelyne Heyer and Frederic Austerlitz Keywords Saguenay Population (Quebec), Recessive Disorders, Cultural Transmission of Fertility, Genetic Drift, Linkage Disequilibrium, Mutation. "One Founder/One Gene Hypothesis in a New Expanding Population" (Heyer 1999) was written as part of a more global project aiming to understand the processes by which several inhe…

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