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Enrico Pessina

Biographic Data

ID7650819
NAMEEnrico Pessina
GIVEN NAMESEnrico
FAMILY NAMEPessina
SIGNATUREPESSINA E
AFFILIATIONSMassachusetts Department of Mental Health
ORCID0000-0003-0485-6319
VERIFIEDYes
TOTAL WORKS3
TOTAL CITATIONS0
WORKS AS AUTHOR3
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2023
LATEST PUBLICATION YEAR2026
H-INDEX0
  • Real-world outcomes of lurasidone augmentation for treatment-resistant bipolar depression

    Open Access•Giorgia Porceddu, Enrico Pessina et al.•ARTICLE•Frontiers in Psychiatry•2026

    Lurasidone appears to be an effective and generally well-tolerated adjunctive option for TRBD. However, remission rates remained low, underscoring the need for further research. In this perspective, lurasidone may contribute to more individualized treatment strategies for difficult-to-treat patients, although confirmatory studies are required to better define its role within precision psychiatry

  • Efficacy and tolerability of vortioxetine monotherapy in SSRI-resistant OCD

    Open Access•Vassilis Martiadis, Enrico Pessina et al.•ARTICLE•Frontiers in Psychiatry•2025

    This study provides preliminary evidence of the efficacy and tolerability of vortioxetine monotherapy in SSRI-resistant OCD. The observed improvements in OCD, depressive and anxiety symptoms suggest that vortioxetine may represent a valuable therapeutic option. Further prospective controlled trials are needed to confirm these findings

  • Cariprazine augmentation in patients with treatment resistant unipolar depression who failed to respond to previous atypical antipsychotic add-on. A case-series

    Open Access•Enrico Pessina, Azzurra Martini et al.•ARTICLE•Frontiers in Psychiatry•2023

    Among individuals receiving an adequate pharmacological treatment for Major Depressive Disorder (MDD), only 30% reach a full symptom recovery; the remaining 70% will experience either a pharmacological response without remission or no response at all thus configuring treatment resistant depression (TRD). After an inadequate response to an antidepressant, possible next step options include optimizing the dose of the current antidepressant, switchi…

No prominent works on this page.

  • Cariprazine augmentation in patients with treatment resistant unipolar depression who failed to respond to previous atypical antipsychotic add-on. A case-series

    Open Access•Enrico Pessina, Azzurra Martini et al.•ARTICLE•Frontiers in Psychiatry•2023

    Among individuals receiving an adequate pharmacological treatment for Major Depressive Disorder (MDD), only 30% reach a full symptom recovery; the remaining 70% will experience either a pharmacological response without remission or no response at all thus configuring treatment resistant depression (TRD). After an inadequate response to an antidepressant, possible next step options include optimizing the dose of the current antidepressant, switchi…

  • Efficacy and tolerability of vortioxetine monotherapy in SSRI-resistant OCD

    Open Access•Vassilis Martiadis, Enrico Pessina et al.•ARTICLE•Frontiers in Psychiatry•2025

    This study provides preliminary evidence of the efficacy and tolerability of vortioxetine monotherapy in SSRI-resistant OCD. The observed improvements in OCD, depressive and anxiety symptoms suggest that vortioxetine may represent a valuable therapeutic option. Further prospective controlled trials are needed to confirm these findings

  • Real-world outcomes of lurasidone augmentation for treatment-resistant bipolar depression

    Open Access•Giorgia Porceddu, Enrico Pessina et al.•ARTICLE•Frontiers in Psychiatry•2026

    Lurasidone appears to be an effective and generally well-tolerated adjunctive option for TRBD. However, remission rates remained low, underscoring the need for further research. In this perspective, lurasidone may contribute to more individualized treatment strategies for difficult-to-treat patients, although confirmatory studies are required to better define its role within precision psychiatry

Anxiety (3 works) · Adverse effect (2 works) · Antidepressant (2 works) · Depression (economics (2 works) · Electroconvulsive Therapy Studies (2 works) · Internal Medicine (2 works) · Major depressive disorder (2 works) · Medicine (2 works) · Psychiatry (2 works) · Tolerability (2 works)

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