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Xiaofeng Lan

Biographic Data

ID7662815
NAMEXiaofeng Lan
GIVEN NAMESXiaofeng
FAMILY NAMELan
SIGNATURELAN X
AFFILIATIONSGuangzhou Medical University
ORCID0000-0002-7042-084X
VERIFIEDYes
TOTAL WORKS6
TOTAL CITATIONS0
WORKS AS AUTHOR6
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2021
LATEST PUBLICATION YEAR2025
H-INDEX0
  • Body mass index is associated with the antidepressant effects of intravenous ketamine in patients with depression

    Open Access•Jian-Qiang Tan, Li-Mei Gu et al.•ARTICLE•Frontiers in Psychiatry•2025

    Our exploratory, post-hoc analysis of an open-label, single-arm study suggests that patients with depression and a higher baseline BMI may experience greater reductions in depressive symptoms compared with those with a lower baseline BMI after receiving six ketamine infusions

  • The core inflammatory factors in patients with major depressive disorder

    Open Access•Yexian Zeng, Bin Sun et al.•ARTICLE•Frontiers in Psychiatry•2023

    IL-1β is the central inflammatory factor in the network, and there is heterogeneity in the core inflammatory factor of MDD with specific depressive dimension symptoms as the main manifestation. In conclusion, inflammatory factors and their links should be prioritized in future theoretical models of MDD and may provide new research targets for MDD intervention and treatment

  • Cognitive Function Mediates the Anti-suicide Effect of Repeated Intravenous Ketamine in Adult Patients With Suicidal Ideation

    Open Access•Yanling Zhou, Chengyu Wang et al.•ARTICLE•Frontiers in Psychiatry•2022

    Depressive symptoms severity and processing speed performance partially mediated improvements in suicidal ideation after repeated ketamine infusions in persons with unipolar or bipolar depressive disorder

  • Plasma Vegf Concentrations and Ketamine's Effects on Suicidal Ideation in Depression With Suicidal Ideation

    Open Access•Wei Zheng, Li-Mei Gu et al.•ARTICLE•Frontiers in Psychiatry•2022

    This preliminary finding does not support a role for VEGF in the antisuicidal effects of serial ketamine treatments in individuals with depression and suicidal ideation. Further research is needed to confirm and expand these findings

  • Pre-treatment Pain Symptoms Influence Antidepressant Response to Ketamine in Depressive Patients

    Open Access•Xiaofeng Lan, Yanling Zhou et al.•ARTICLE•Frontiers in Psychiatry•2022

    A significant and rapid improvement in depressive symptoms was observed in patients with depression and pain after ketamine treatment. Ketamine may be a novel and promising antidepressant preferentially for the therapy of depression with severe pain

  • Association of Vegf With Antianhedonic Effects of Repeated-Dose Intravenous Ketamine in Treatment-Refractory Depression

    Open Access•Wei Zheng, Li-Mei Gu et al.•ARTICLE•Frontiers in Psychiatry•2021

    Objectives: To first explore the role of plasma vascular endothelial growth factor (VEGF) concentrations in ketamine's antianhedonic effects, focusing on Chinese patients with treatment-refractory depression (TRD). Methods: Seventy-eight patients with treatment-refractory major depressive disorder (MDD) or bipolar disorder (BD) were treated with six ketamine infusions (0.5 mg/kg). Levels of anhedonia were measured using the Montgomery-Åsberg Depr…

No prominent works on this page.

  • Association of Vegf With Antianhedonic Effects of Repeated-Dose Intravenous Ketamine in Treatment-Refractory Depression

    Open Access•Wei Zheng, Li-Mei Gu et al.•ARTICLE•Frontiers in Psychiatry•2021

    Objectives: To first explore the role of plasma vascular endothelial growth factor (VEGF) concentrations in ketamine's antianhedonic effects, focusing on Chinese patients with treatment-refractory depression (TRD). Methods: Seventy-eight patients with treatment-refractory major depressive disorder (MDD) or bipolar disorder (BD) were treated with six ketamine infusions (0.5 mg/kg). Levels of anhedonia were measured using the Montgomery-Åsberg Depr…

  • Cognitive Function Mediates the Anti-suicide Effect of Repeated Intravenous Ketamine in Adult Patients With Suicidal Ideation

    Open Access•Yanling Zhou, Chengyu Wang et al.•ARTICLE•Frontiers in Psychiatry•2022

    Depressive symptoms severity and processing speed performance partially mediated improvements in suicidal ideation after repeated ketamine infusions in persons with unipolar or bipolar depressive disorder

  • Plasma Vegf Concentrations and Ketamine's Effects on Suicidal Ideation in Depression With Suicidal Ideation

    Open Access•Wei Zheng, Li-Mei Gu et al.•ARTICLE•Frontiers in Psychiatry•2022

    This preliminary finding does not support a role for VEGF in the antisuicidal effects of serial ketamine treatments in individuals with depression and suicidal ideation. Further research is needed to confirm and expand these findings

  • Pre-treatment Pain Symptoms Influence Antidepressant Response to Ketamine in Depressive Patients

    Open Access•Xiaofeng Lan, Yanling Zhou et al.•ARTICLE•Frontiers in Psychiatry•2022

    A significant and rapid improvement in depressive symptoms was observed in patients with depression and pain after ketamine treatment. Ketamine may be a novel and promising antidepressant preferentially for the therapy of depression with severe pain

  • The core inflammatory factors in patients with major depressive disorder

    Open Access•Yexian Zeng, Bin Sun et al.•ARTICLE•Frontiers in Psychiatry•2023

    IL-1β is the central inflammatory factor in the network, and there is heterogeneity in the core inflammatory factor of MDD with specific depressive dimension symptoms as the main manifestation. In conclusion, inflammatory factors and their links should be prioritized in future theoretical models of MDD and may provide new research targets for MDD intervention and treatment

  • Body mass index is associated with the antidepressant effects of intravenous ketamine in patients with depression

    Open Access•Jian-Qiang Tan, Li-Mei Gu et al.•ARTICLE•Frontiers in Psychiatry•2025

    Our exploratory, post-hoc analysis of an open-label, single-arm study suggests that patients with depression and a higher baseline BMI may experience greater reductions in depressive symptoms compared with those with a lower baseline BMI after receiving six ketamine infusions

Medicine (6 works) · Tryptophan and brain disorders (6 works) · Ketamine (5 works) · Major depressive disorder (5 works) · Treatment of Major Depression (5 works) · Depression (economics (4 works) · Internal Medicine (4 works) · Psychiatry (4 works) · Psychology (4 works) · Anesthesia (3 works)

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