Getrude Ncube
Biographic Data
| ID | 7749711 |
|---|---|
| NAME | Getrude Ncube |
| GIVEN NAMES | Getrude |
| FAMILY NAME | Ncube |
| SIGNATURE | NCUBE G |
| AFFILIATIONS | Ministry of Health and Child Welfare |
| ORCID | 0000-0002-8873-8901 |
| VERIFIED | Yes |
| TOTAL WORKS | 16 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 16 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2017 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
Perceptions of pre-exposure prophylaxis among sexually active adolescent girls and young women in Zimbabwe–A qualitative study
Adolescent girls and young women (AGYW; aged 15–24 years) in Zimbabwe face high risk of contracting HIV. Despite proven effectiveness of Pre-Exposure Prophylaxis (PrEP), its uptake and continuation among AGYW is low. We aimed to explore views on PrEP, norms around sexual behaviour and how programs can improve PrEP uptake among this group. From December 2021 to March 2023 nine focus group discussions were held with 92 (8–12 per group) sexually act…
Who has never tested for HIV following a community-based distribution of HIV self-test kits? Establishing associated predictors in rural Zimbabwe
In 2023, Zimbabwe attained the 95-95-95 UNAIDS targets. However, some sub-populations are substantially less likely to have tested for HIV. Knowledge of characteristics of these groups is crucial in designing interventions that address their needs. We estimated the prevalence and predictors of “never-having tested for HIV” status following community-based distribution of HIV self-test kits in rural Zimbabwe. We analysed data from a household surv…
Integration of a vertical voluntary medical male circumcision program into routine health services in Zimbabwe
The global health community has recognized the importance of integrating and sustaining health programs within national health systems rather than managing stand-alone ‘vertical’ interventions. Corresponding with these objectives, international aid donors are embracing the principle of localization. Voluntary Medical Male Circumcision (VMMC) in Zimbabwe is a large vertical HIV prevention program that was primarily funded through development assis…
A mixed-method study of feasibility and acceptability of the Dapivirine vaginal ring among adolescent girls and young women (Agyw) in selected Zimbabwean districts
The Dapivirine vaginal ring (DPV-VR) is an intravaginal silicone ring that delivers an antiretroviral drug (Dapivirine) directly to vaginal tissues for 28 days. This ring protects women against HIV during the receptive vaginal sex at the site of potential infection. In 2021, the WHO recommended DPV as an additional prevention method for high-risk women for HIV with other approaches. With its discreet usage and disposal, DPV-VR has become a prefer…
HIV incidence and prevalence projections for Zimbabwe
Introduction : Understanding how HIV epidemics are likely to behave in the future is key to informing HIV response strategies in low-income countries. Up-to-date HIV epidemiological estimates are important for policy decision- making, but surveillance data can be out of date. This study compared forecasts from HIV epidemiological models. Methods : Five independent modelling groups (EMOD-HIV, Goals, HIV Synthesis, Optima and PopART-IBM) calibrated…
Optimising the adult HIV testing services screening tool to predict positivity yield in Zimbabwe, 2022
HIV positivity yield declined against increasing testing volumes in Zimbabwe, from 20% (1.65 million tests) in 2011 to 6% (3 million tests) in 2018. A screening tool was introduced to aid testers to identify clients likely to obtain a positive diagnosis of HIV. Consequently, testing volumes declined to 2.3 million in 2019 but positivity declined to 5% prompting the evaluation and validation of the tool to improve its precision in predicting posit…
Catalyzing action on HIV/SRH integration
The HIV pandemic has long revealed the inequities and fault lines in societies, one of the most tenacious being the pandemic's disproportionate impact on adolescent girls and young women. In east and southern Africa, renewed global action is needed to invigorate an effective yet undervalued approach to expanding HIV prevention and improving women's health: integration of quality HIV and sexual and reproductive health (SRH) services. The urgency o…
High HIV Positivity Rates Following Large-Scale HIV Self-Testing Implementation in Zimbabwe, 2018–2020
Introduction: HIV self-testing (HIV-ST) is an innovative strategy to increase HIV case identification. This analysis shares the outcomes of HIV-ST implementation within the Zimbabwe HIV Care and Treatment (ZHCT) project for the period October 2018–March, 2020. Materials and Methods: We extracted HIV-ST data for the period October 2018 to March 2020 from the project database and assessed (1) the proportion of reactive HIV-ST results; (2) the conco…
Innovative demand creation strategies to increase voluntary medical male circumcision uptake
INTRODUCTION: Reaching men aged 20-35 years, the group at greatest risk of HIV, with voluntary medical male circumcision (VMMC) remains a challenge. We assessed the impact of two VMMC demand creation approaches targeting this age group in a randomised controlled trial (RCT). METHODS: We conducted a 2×2 factorial RCT comparing arms with and without two interventions: (1) standard demand creation augmented by human-centred design (HCD)-informed app…
Community-based HIV self-testing
BACKGROUND: HIV self-testing (HIVST) requires linkage to post-test services to maximise its benefits. We evaluated effect of supply-side incentivisation on linkage following community-based HIVST and evaluated time-trends in facility-based antiretroviral therapy (ART) initiations. METHODS: From August 2016 to August 2017 community-based distributors (CBDs) in 38 rural Zimbabwean communities distributed HIVST door-to-door in 19-25 day campaigns. C…
Comparison of community-led distribution of HIV self-tests kits with distribution by paid distributors
BACKGROUND: We compared community-led versus an established community-based HIV self-testing (HIVST) model in rural Zimbabwe using a cluster-randomised trial. METHODS: Forty village groups were randomised 1:1 using restricted randomisation to community-led HIVST, where communities planned and implemented HIVST distribution for 4 weeks, or paid distribution (PD), where distributors were paid US$50 to distribute kits door-to-door over 4 weeks. Indi…
Relative efficiency of demand creation strategies to increase voluntary medical male circumcision uptake
BACKGROUND: Supply and demand-side factors continue to undermine voluntary medical male circumcision (VMMC) uptake. We assessed relative economic costs of four VMMC demand creation/service-delivery modalities as part of a randomised controlled trial in Zimbabwe. METHODS: Interpersonal communication agents were trained and incentivised to generate VMMC demand across five districts using four demand creation modalities (standard demand creation (SD…
Efficiency in PrEP Delivery
Although oral PrEP is highly effective at preventing HIV acquisition, optimizing continuation among beneficiaries is challenging in many settings. We estimated the costs of delivering oral PrEP to populations at risk of HIV in seven clinics in Zimbabwe. Full annual economic costs of oral PrEP initiations and continuation visits were estimated from the providers' perspective for a six-clinic NGO network and one government SGBV clinic in Zimbabwe (…
Use and awareness of and willingness to self-test for HIV
In 2015-16, many Malawian and Zimbabwean men had never tested for HIV. Despite low awareness and minimal HIVST experience, willingness to self-test was high among Zimbabwean men, especially older men with moderate-to-high HIV-related sexual risk. These data provide a valuable baseline against which to investigate population-level uptake of HIVST as programmes scale up. Programmes introducing, or planning to introduce, HIVST should consider includ…
The effectiveness and cost-effectiveness of community-based lay distribution of HIV self-tests in increasing uptake of HIV testing among adults in rural Malawi and rural and peri-urban Zambia
Clinicaltrials.gov, Malawi: NCT02718274 , 18 March 2016; Zambia: NCT02793804 , 3 June 2016. Protocol date: 21 February 2018
Unpacking early infant male circumcision decision-making using qualitative findings from Zimbabwe
BACKGROUND: Early infant male circumcision (EIMC) has been identified as a key HIV prevention intervention. Exploring the decision-making process for adoption of EIMC for HIV prevention among parents and other key stakeholders is critical for designing effective demand creation interventions to maximize uptake, roll out and impact in preventing HIV. This paper describes key players, decisions and actions involved in the EIMC decision-making proce…
No prominent works on this page.
Unpacking early infant male circumcision decision-making using qualitative findings from Zimbabwe
BACKGROUND: Early infant male circumcision (EIMC) has been identified as a key HIV prevention intervention. Exploring the decision-making process for adoption of EIMC for HIV prevention among parents and other key stakeholders is critical for designing effective demand creation interventions to maximize uptake, roll out and impact in preventing HIV. This paper describes key players, decisions and actions involved in the EIMC decision-making proce…
The effectiveness and cost-effectiveness of community-based lay distribution of HIV self-tests in increasing uptake of HIV testing among adults in rural Malawi and rural and peri-urban Zambia
Clinicaltrials.gov, Malawi: NCT02718274 , 18 March 2016; Zambia: NCT02793804 , 3 June 2016. Protocol date: 21 February 2018
Use and awareness of and willingness to self-test for HIV
In 2015-16, many Malawian and Zimbabwean men had never tested for HIV. Despite low awareness and minimal HIVST experience, willingness to self-test was high among Zimbabwean men, especially older men with moderate-to-high HIV-related sexual risk. These data provide a valuable baseline against which to investigate population-level uptake of HIVST as programmes scale up. Programmes introducing, or planning to introduce, HIVST should consider includ…
High HIV Positivity Rates Following Large-Scale HIV Self-Testing Implementation in Zimbabwe, 2018–2020
Introduction: HIV self-testing (HIV-ST) is an innovative strategy to increase HIV case identification. This analysis shares the outcomes of HIV-ST implementation within the Zimbabwe HIV Care and Treatment (ZHCT) project for the period October 2018–March, 2020. Materials and Methods: We extracted HIV-ST data for the period October 2018 to March 2020 from the project database and assessed (1) the proportion of reactive HIV-ST results; (2) the conco…
Innovative demand creation strategies to increase voluntary medical male circumcision uptake
INTRODUCTION: Reaching men aged 20-35 years, the group at greatest risk of HIV, with voluntary medical male circumcision (VMMC) remains a challenge. We assessed the impact of two VMMC demand creation approaches targeting this age group in a randomised controlled trial (RCT). METHODS: We conducted a 2×2 factorial RCT comparing arms with and without two interventions: (1) standard demand creation augmented by human-centred design (HCD)-informed app…
Community-based HIV self-testing
BACKGROUND: HIV self-testing (HIVST) requires linkage to post-test services to maximise its benefits. We evaluated effect of supply-side incentivisation on linkage following community-based HIVST and evaluated time-trends in facility-based antiretroviral therapy (ART) initiations. METHODS: From August 2016 to August 2017 community-based distributors (CBDs) in 38 rural Zimbabwean communities distributed HIVST door-to-door in 19-25 day campaigns. C…
Comparison of community-led distribution of HIV self-tests kits with distribution by paid distributors
BACKGROUND: We compared community-led versus an established community-based HIV self-testing (HIVST) model in rural Zimbabwe using a cluster-randomised trial. METHODS: Forty village groups were randomised 1:1 using restricted randomisation to community-led HIVST, where communities planned and implemented HIVST distribution for 4 weeks, or paid distribution (PD), where distributors were paid US$50 to distribute kits door-to-door over 4 weeks. Indi…
Relative efficiency of demand creation strategies to increase voluntary medical male circumcision uptake
BACKGROUND: Supply and demand-side factors continue to undermine voluntary medical male circumcision (VMMC) uptake. We assessed relative economic costs of four VMMC demand creation/service-delivery modalities as part of a randomised controlled trial in Zimbabwe. METHODS: Interpersonal communication agents were trained and incentivised to generate VMMC demand across five districts using four demand creation modalities (standard demand creation (SD…
Efficiency in PrEP Delivery
Although oral PrEP is highly effective at preventing HIV acquisition, optimizing continuation among beneficiaries is challenging in many settings. We estimated the costs of delivering oral PrEP to populations at risk of HIV in seven clinics in Zimbabwe. Full annual economic costs of oral PrEP initiations and continuation visits were estimated from the providers' perspective for a six-clinic NGO network and one government SGBV clinic in Zimbabwe (…
Optimising the adult HIV testing services screening tool to predict positivity yield in Zimbabwe, 2022
HIV positivity yield declined against increasing testing volumes in Zimbabwe, from 20% (1.65 million tests) in 2011 to 6% (3 million tests) in 2018. A screening tool was introduced to aid testers to identify clients likely to obtain a positive diagnosis of HIV. Consequently, testing volumes declined to 2.3 million in 2019 but positivity declined to 5% prompting the evaluation and validation of the tool to improve its precision in predicting posit…
Catalyzing action on HIV/SRH integration
The HIV pandemic has long revealed the inequities and fault lines in societies, one of the most tenacious being the pandemic's disproportionate impact on adolescent girls and young women. In east and southern Africa, renewed global action is needed to invigorate an effective yet undervalued approach to expanding HIV prevention and improving women's health: integration of quality HIV and sexual and reproductive health (SRH) services. The urgency o…
Perceptions of pre-exposure prophylaxis among sexually active adolescent girls and young women in Zimbabwe–A qualitative study
Adolescent girls and young women (AGYW; aged 15–24 years) in Zimbabwe face high risk of contracting HIV. Despite proven effectiveness of Pre-Exposure Prophylaxis (PrEP), its uptake and continuation among AGYW is low. We aimed to explore views on PrEP, norms around sexual behaviour and how programs can improve PrEP uptake among this group. From December 2021 to March 2023 nine focus group discussions were held with 92 (8–12 per group) sexually act…
Who has never tested for HIV following a community-based distribution of HIV self-test kits? Establishing associated predictors in rural Zimbabwe
In 2023, Zimbabwe attained the 95-95-95 UNAIDS targets. However, some sub-populations are substantially less likely to have tested for HIV. Knowledge of characteristics of these groups is crucial in designing interventions that address their needs. We estimated the prevalence and predictors of “never-having tested for HIV” status following community-based distribution of HIV self-test kits in rural Zimbabwe. We analysed data from a household surv…
Integration of a vertical voluntary medical male circumcision program into routine health services in Zimbabwe
The global health community has recognized the importance of integrating and sustaining health programs within national health systems rather than managing stand-alone ‘vertical’ interventions. Corresponding with these objectives, international aid donors are embracing the principle of localization. Voluntary Medical Male Circumcision (VMMC) in Zimbabwe is a large vertical HIV prevention program that was primarily funded through development assis…
A mixed-method study of feasibility and acceptability of the Dapivirine vaginal ring among adolescent girls and young women (Agyw) in selected Zimbabwean districts
The Dapivirine vaginal ring (DPV-VR) is an intravaginal silicone ring that delivers an antiretroviral drug (Dapivirine) directly to vaginal tissues for 28 days. This ring protects women against HIV during the receptive vaginal sex at the site of potential infection. In 2021, the WHO recommended DPV as an additional prevention method for high-risk women for HIV with other approaches. With its discreet usage and disposal, DPV-VR has become a prefer…
HIV incidence and prevalence projections for Zimbabwe
Introduction : Understanding how HIV epidemics are likely to behave in the future is key to informing HIV response strategies in low-income countries. Up-to-date HIV epidemiological estimates are important for policy decision- making, but surveillance data can be out of date. This study compared forecasts from HIV epidemiological models. Methods : Five independent modelling groups (EMOD-HIV, Goals, HIV Synthesis, Optima and PopART-IBM) calibrated…
Medicine (15 works) · HIV/AIDS Research and Interventions (14 works) · Environmental health (8 works) · Family medicine (8 works) · Adolescent Sexual and Reproductive Health (6 works) · Nursing (6 works) · Demography (5 works) · Economics (5 works) · HIV Research and Treatment (5 works) · HIV, Drug Use, Sexual Risk (5 works)