Philippa C Matthews
Biographic Data
| ID | 7765965 |
|---|---|
| NAME | Philippa C Matthews |
| GIVEN NAMES | Philippa C |
| FAMILY NAME | Matthews |
| SIGNATURE | MATTHEWS P C |
| AFFILIATIONS | University College Hospital |
| ORCID | 0000-0002-4036-4269 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 10 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2019 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
“It would be better for those of us who have the disease not to be ashamed”
Chronic hepatitis B infection (CHB) causes over 1 million deaths annually, with a large burden of morbidity and mortality in the WHO-African Region (WHO-AFRO) where
Is health, growth and development impaired in children who are Hepatitis B-exposed but uninfected
An estimated 254 million people are living with chronic hepatitis B virus (HBV) infection worldwide. Many infants are born to mothers with HBV but do not themselves acquire the infection. It is unclear whether this exposure to HBV in early life - without the development of active infection - may be associated with adverse outcomes. We propose the term “HBV-exposed uninfected (HBEU)”, drawing parallels with the HIV field which recognises that chil…
Infecting minds
Exploring what shapes attitudes towards vaccines in communities provides opportunities to understand the reasoning behind how people make decisions about whether to take a vaccine in different geographical and cultural spaces. The exploration of contexts, exposures and circumstances provide insights into perceptions and behaviour. Deeper engagement with local communities is crucial to develop evidence that can inform vaccine interventions. Assump…
Pandemic preparedness
Whilst many lessons were learned from the COVID-19 pandemic, ongoing reflection is needed to develop and maintain preparedness for future outbreaks. Within the field of infectious disease and public health there remain silos and hierarchies in interdisciplinary work, with the risk that humanities and social sciences remain on the epistemological peripheries. However, these disciplines offer insights, expertise and tools that contribute to underst…
Retrospective analysis of hospital electronic health records reveals unseen cases of acute hepatitis with unknown aetiology in adults in Oxfordshire
Our results highlight an increase in AHUA in adults coinciding with the period of the outbreak in children, but not linked to documented HAdV infection. Tracking changes in routinely collected clinical data through EHR could be used to support outbreak surveillance
A systematic review of Hepatitis B virus (HBV) prevalence and genotypes in Kenya
The aim of this systematic review and meta-analysis is to evaluate available prevalence and viral sequencing data representing chronic hepatitis B (CHB) infection in Kenya. More than 20% of the global disease burden from CHB is in Africa, however there is minimal high quality seroprevalence data from individual countries and little viral sequencing data available to represent the continent. We undertook a systematic review of the prevalence and g…
Hepatitis B Virus
Hepatitis B virus (HBV) is a blood-borne virus that establishes chronic liver infection, associated with potential complications of cirrhosis and/or hepatocellular carcinoma (HCC). As such, it poses a major threat to global public health, accounting for 300 million chronic infections, and more than 500,000 deaths each year It can also be regarded as a 'syndemic' challenge-namely, as one component of multiple, complex interacting health and social…
The global impact of the Covid-19 pandemic on the prevention, diagnosis and treatment of hepatitis B virus (HBV) infection
The COVID-19 pandemic caused by the SARS-CoV-2 virus has resulted in a myriad of interventions with the urgent aim of reducing the public health impact of this virus. However, a wealth of evidence both from high-income and low-income countries is accruing on the broader consequences of such interventions on economic and public health inequalities, as well as on pre-existing programmes targeting endemic pathogens. We provide an overview of the imp…
Fair data needed to liberate hepatitis B virus (HBV) from the catch-22 of neglect
Modelling cost-effectiveness of tenofovir for prevention of mother to child transmission of hepatitis B virus (HBV) infection in South Africa
Given the long-term health burden for individuals and economic burden for society associated with chronic HBV infection, screening pregnant women and providing tenofovir for all who test HBsAg+ may be a cost-effective strategy for South Africa and other low/middle income settings
No prominent works on this page.
Fair data needed to liberate hepatitis B virus (HBV) from the catch-22 of neglect
Modelling cost-effectiveness of tenofovir for prevention of mother to child transmission of hepatitis B virus (HBV) infection in South Africa
Given the long-term health burden for individuals and economic burden for society associated with chronic HBV infection, screening pregnant women and providing tenofovir for all who test HBsAg+ may be a cost-effective strategy for South Africa and other low/middle income settings
The global impact of the Covid-19 pandemic on the prevention, diagnosis and treatment of hepatitis B virus (HBV) infection
The COVID-19 pandemic caused by the SARS-CoV-2 virus has resulted in a myriad of interventions with the urgent aim of reducing the public health impact of this virus. However, a wealth of evidence both from high-income and low-income countries is accruing on the broader consequences of such interventions on economic and public health inequalities, as well as on pre-existing programmes targeting endemic pathogens. We provide an overview of the imp…
Hepatitis B Virus
Hepatitis B virus (HBV) is a blood-borne virus that establishes chronic liver infection, associated with potential complications of cirrhosis and/or hepatocellular carcinoma (HCC). As such, it poses a major threat to global public health, accounting for 300 million chronic infections, and more than 500,000 deaths each year It can also be regarded as a 'syndemic' challenge-namely, as one component of multiple, complex interacting health and social…
A systematic review of Hepatitis B virus (HBV) prevalence and genotypes in Kenya
The aim of this systematic review and meta-analysis is to evaluate available prevalence and viral sequencing data representing chronic hepatitis B (CHB) infection in Kenya. More than 20% of the global disease burden from CHB is in Africa, however there is minimal high quality seroprevalence data from individual countries and little viral sequencing data available to represent the continent. We undertook a systematic review of the prevalence and g…
Pandemic preparedness
Whilst many lessons were learned from the COVID-19 pandemic, ongoing reflection is needed to develop and maintain preparedness for future outbreaks. Within the field of infectious disease and public health there remain silos and hierarchies in interdisciplinary work, with the risk that humanities and social sciences remain on the epistemological peripheries. However, these disciplines offer insights, expertise and tools that contribute to underst…
Retrospective analysis of hospital electronic health records reveals unseen cases of acute hepatitis with unknown aetiology in adults in Oxfordshire
Our results highlight an increase in AHUA in adults coinciding with the period of the outbreak in children, but not linked to documented HAdV infection. Tracking changes in routinely collected clinical data through EHR could be used to support outbreak surveillance
“It would be better for those of us who have the disease not to be ashamed”
Chronic hepatitis B infection (CHB) causes over 1 million deaths annually, with a large burden of morbidity and mortality in the WHO-African Region (WHO-AFRO) where
Is health, growth and development impaired in children who are Hepatitis B-exposed but uninfected
An estimated 254 million people are living with chronic hepatitis B virus (HBV) infection worldwide. Many infants are born to mothers with HBV but do not themselves acquire the infection. It is unclear whether this exposure to HBV in early life - without the development of active infection - may be associated with adverse outcomes. We propose the term “HBV-exposed uninfected (HBEU)”, drawing parallels with the HIV field which recognises that chil…
Infecting minds
Exploring what shapes attitudes towards vaccines in communities provides opportunities to understand the reasoning behind how people make decisions about whether to take a vaccine in different geographical and cultural spaces. The exploration of contexts, exposures and circumstances provide insights into perceptions and behaviour. Deeper engagement with local communities is crucial to develop evidence that can inform vaccine interventions. Assump…
Medicine (8 works) · Public health (6 works) · Disease (5 works) · Environmental health (5 works) · Hepatitis B virus (5 works) · Hepatitis B (4 works) · Hepatitis B Virus Studies (4 works) · Hepatitis C virus research (4 works) · Immunology (4 works) · Nursing (4 works)