Timothy Russell
Datos Biográficos
| ID | 7766212 |
|---|---|
| NOMBRE | Timothy Russell |
| NOMBRES | Timothy |
| APELLIDO | Russell |
| FIRMA | RUSSELL T |
| AFILIACIONES | London School of Hygiene & Tropical Medicine |
| ORCID | 0000-0001-5610-6080 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 10 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 10 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2020 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Estimating the basic reproduction number of measles in low-and middle-income settings using 172 seroprevalence studies
The basic reproduction number, R 0 , is an epidemiological measure to describe the transmissibility of infectious diseases and evaluate the potential effect of interventions. Measles R 0 has historically been considered to be between 12–18, with contextual factors contributing to its heterogeneity, but has rarely been estimated using data across multiple countries. Our study aims to estimate measles R 0 in low- and middle-income countries using a…
The impact of Covid-19 vaccination in prisons in England and Wales
The impact of vaccination in prison settings was highly dependent on early and rapid vaccine delivery. If administered to both those living and working in prison prior to an outbreak occurring, vaccines could substantially reduce COVID-19-related morbidity and mortality in prison settings
The local burden of disease during the first wave of the Covid-19 epidemic in England
Limitations in testing capacity biased the observed trajectory of COVID-19 infections throughout the first wave. Basing inference on COVID-19-related mortality and higher-coverage testing later in the time period, we could explore the extent of this bias more explicitly. Evidence points towards substantial under-representation of initial growth and peak magnitude of infections nationally, to which different parts of the country contribute unequal…
Global, regional, and national estimates of the population at increased risk of severe Covid-19 due to underlying health conditions in 2020
BACKGROUND: The risk of severe COVID-19 if an individual becomes infected is known to be higher in older individuals and those with underlying health conditions. Understanding the number of individuals at increased risk of severe COVID-19 and how this varies between countries should inform the design of possible strategies to shield or vaccinate those at highest risk. METHODS: We estimated the number of individuals at increased risk of severe dis…
Feasibility of controlling Covid-19 outbreaks by isolation of cases and contacts
Background Isolation of cases and contact tracing is used to control outbreaks of infectious diseases, and has been used for coronavirus disease 2019 (COVID-19). Whether this strategy will achieve control depends on characteristics of both the pathogen and the response. Here we use a mathematical model to assess if isolation and contact tracing are able to control onwards transmission from imported cases of COVID-19. Methods We developed a stocha…
The effect of control strategies to reduce social mixing on outcomes of the Covid-19 epidemic in Wuhan, China
BACKGROUND: In December, 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, emerged in Wuhan, China. Since then, the city of Wuhan has taken unprecedented measures in response to the outbreak, including extended school and workplace closures. We aimed to estimate the effects of physical distancing measures on the progression of the COVID-19 epidemic, hoping to provide some insights for the rest of the world. …
Age-dependent effects in the transmission and control of Covid-19 epidemics
The COVID-19 pandemic has shown a markedly low proportion of cases among children1–4. Age disparities in observed cases could be explained by children having lower susceptibility to infection, lower propensity to show clinical symptoms or both. We evaluate these possibilities by fitting an age-structured mathematical model to epidemic data from China, Italy, Japan, Singapore, Canada and South Korea. We estimate that susceptibility to infection in…
Effects of non-pharmaceutical interventions on Covid-19 cases, deaths, and demand for hospital services in the UK
Background Non-pharmaceutical interventions have been implemented to reduce transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the UK. Projecting the size of an unmitigated epidemic and the potential effect of different control measures has been crucial to support evidence-based policy making during the early stages of the epidemic. This study assesses the potential impact of different control measures for mitigating …
Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of Sars-CoV-2 in different settings
BACKGROUND: The isolation of symptomatic cases and tracing of contacts has been used as an early COVID-19 containment measure in many countries, with additional physical distancing measures also introduced as outbreaks have grown. To maintain control of infection while also reducing disruption to populations, there is a need to understand what combination of measures-including novel digital tracing approaches and less intensive physical distancin…
Early dynamics of transmission and control of Covid-19
BACKGROUND: An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to 95 333 confirmed cases as of March 5, 2020. Understanding the early transmission dynamics of the infection and evaluating the effectiveness of control measures is crucial for assessing the potential for sustained transmission to occur in new areas. Combining a mathematical model of severe SARS-CoV-2 transmission with four datasets from within and ou…
Sin obras prominentes en esta página.
Global, regional, and national estimates of the population at increased risk of severe Covid-19 due to underlying health conditions in 2020
BACKGROUND: The risk of severe COVID-19 if an individual becomes infected is known to be higher in older individuals and those with underlying health conditions. Understanding the number of individuals at increased risk of severe COVID-19 and how this varies between countries should inform the design of possible strategies to shield or vaccinate those at highest risk. METHODS: We estimated the number of individuals at increased risk of severe dis…
Feasibility of controlling Covid-19 outbreaks by isolation of cases and contacts
Background Isolation of cases and contact tracing is used to control outbreaks of infectious diseases, and has been used for coronavirus disease 2019 (COVID-19). Whether this strategy will achieve control depends on characteristics of both the pathogen and the response. Here we use a mathematical model to assess if isolation and contact tracing are able to control onwards transmission from imported cases of COVID-19. Methods We developed a stocha…
The effect of control strategies to reduce social mixing on outcomes of the Covid-19 epidemic in Wuhan, China
BACKGROUND: In December, 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, emerged in Wuhan, China. Since then, the city of Wuhan has taken unprecedented measures in response to the outbreak, including extended school and workplace closures. We aimed to estimate the effects of physical distancing measures on the progression of the COVID-19 epidemic, hoping to provide some insights for the rest of the world. …
Age-dependent effects in the transmission and control of Covid-19 epidemics
The COVID-19 pandemic has shown a markedly low proportion of cases among children1–4. Age disparities in observed cases could be explained by children having lower susceptibility to infection, lower propensity to show clinical symptoms or both. We evaluate these possibilities by fitting an age-structured mathematical model to epidemic data from China, Italy, Japan, Singapore, Canada and South Korea. We estimate that susceptibility to infection in…
Effects of non-pharmaceutical interventions on Covid-19 cases, deaths, and demand for hospital services in the UK
Background Non-pharmaceutical interventions have been implemented to reduce transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the UK. Projecting the size of an unmitigated epidemic and the potential effect of different control measures has been crucial to support evidence-based policy making during the early stages of the epidemic. This study assesses the potential impact of different control measures for mitigating …
Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of Sars-CoV-2 in different settings
BACKGROUND: The isolation of symptomatic cases and tracing of contacts has been used as an early COVID-19 containment measure in many countries, with additional physical distancing measures also introduced as outbreaks have grown. To maintain control of infection while also reducing disruption to populations, there is a need to understand what combination of measures-including novel digital tracing approaches and less intensive physical distancin…
Early dynamics of transmission and control of Covid-19
BACKGROUND: An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to 95 333 confirmed cases as of March 5, 2020. Understanding the early transmission dynamics of the infection and evaluating the effectiveness of control measures is crucial for assessing the potential for sustained transmission to occur in new areas. Combining a mathematical model of severe SARS-CoV-2 transmission with four datasets from within and ou…
The impact of Covid-19 vaccination in prisons in England and Wales
The impact of vaccination in prison settings was highly dependent on early and rapid vaccine delivery. If administered to both those living and working in prison prior to an outbreak occurring, vaccines could substantially reduce COVID-19-related morbidity and mortality in prison settings
The local burden of disease during the first wave of the Covid-19 epidemic in England
Limitations in testing capacity biased the observed trajectory of COVID-19 infections throughout the first wave. Basing inference on COVID-19-related mortality and higher-coverage testing later in the time period, we could explore the extent of this bias more explicitly. Evidence points towards substantial under-representation of initial growth and peak magnitude of infections nationally, to which different parts of the country contribute unequal…
Estimating the basic reproduction number of measles in low-and middle-income settings using 172 seroprevalence studies
The basic reproduction number, R 0 , is an epidemiological measure to describe the transmissibility of infectious diseases and evaluate the potential effect of interventions. Measles R 0 has historically been considered to be between 12–18, with contextual factors contributing to its heterogeneity, but has rarely been estimated using data across multiple countries. Our study aims to estimate measles R 0 in low- and middle-income countries using a…
COVID-19 epidemiological studies (10 obras) · Medicine (9 obras) · Coronavirus disease 2019 (COVID-19) (7 obras) · Disease (7 obras) · Environmental health (6 obras) · Demography (5 obras) · Outbreak (5 obras) · Pandemic (5 obras) · Population (5 obras) · Transmission (telecommunications) (5 obras)