Christopher S McMahan
Biographic Data
| ID | 7783997 |
|---|---|
| NAME | Christopher S McMahan |
| GIVEN NAMES | Christopher S |
| FAMILY NAME | McMahan |
| SIGNATURE | MCMAHAN C S |
| AFFILIATIONS | Clemson University |
| ORCID | 0000-0001-5056-9615 |
| VERIFIED | Yes |
| TOTAL WORKS | 5 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 5 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2021 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Bayesian Machine Learning Tools for Alcohol Use Disorder Research
Alcohol use disorder (AUD) research faces significant challenges in capturing individual heterogeneity and complex temporal patterns in drinking behaviors. Standard statistical methods fail to account for within-person variability and between-person differences, while existing machine learning algorithms are not designed for hierarchical, longitudinal data structures common in AUD research. We developed a comprehensive R package implementing 30 B…
Covid-19 vaccine effectiveness against general Sars-CoV-2 infection from the omicron variant
We aim to estimate the effectiveness of 2-dose and 3-dose mRNA vaccination (BNT162b2 and mRNA-1273) against general Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection (asymptomatic or symptomatic) caused by the omicron BA.1 variant. This propensity-score matched retrospective cohort study takes place in a large public university undergoing weekly Coronavirus Disease 2019 (Covid-19) testing in South Carolina, USA. The populatio…
Assessing Opioid Use Disorder Treatments in Trials Subject to Non-Adherence via a Functional Generalized Linear Mixed-Effects Model
The opioid crisis in the United States poses a major threat to public health due to psychiatric and infectious disease comorbidities and death due to opioid use disorder (OUD). OUD is characterized by patterns of opioid misuse leading to persistent heavy use and overdose. The standard of care for treatment of OUD is medication-assisted treatment, in combination with behavioral therapy. Medications for opioid use disorder have been shown to improv…
Effects of Buprenorphine Dose and Therapeutic Engagement on Illicit Opiate Use in Opioid Use Disorder Treatment Trials
The impact of agonist dose and of physician, staff and patient engagement on treatment have not been evaluated together in an analysis of treatment for opioid use disorder. Our hypotheses were that greater agonist dose and therapeutic engagement would be associated with reduced illicit opiate use in a time-dependent manner. Publicly-available treatment data from six buprenorphine efficacy and safety trials from the Federally-supported Clinical Tr…
The impact of phased university reopenings on mitigating the spread of Covid-19
Unless highly effective mitigation measures are in place, a reopening with pre-arrival testing substantially reduces peak number of active infections throughout the semester and preserves university resources compared to the simultaneous return of all students to campus. Phased reopenings allow institutions to ensure sufficient resources are in place, improve disease mitigation strategies, or if needed, preemptively move online before the return …
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The impact of phased university reopenings on mitigating the spread of Covid-19
Unless highly effective mitigation measures are in place, a reopening with pre-arrival testing substantially reduces peak number of active infections throughout the semester and preserves university resources compared to the simultaneous return of all students to campus. Phased reopenings allow institutions to ensure sufficient resources are in place, improve disease mitigation strategies, or if needed, preemptively move online before the return …
Assessing Opioid Use Disorder Treatments in Trials Subject to Non-Adherence via a Functional Generalized Linear Mixed-Effects Model
The opioid crisis in the United States poses a major threat to public health due to psychiatric and infectious disease comorbidities and death due to opioid use disorder (OUD). OUD is characterized by patterns of opioid misuse leading to persistent heavy use and overdose. The standard of care for treatment of OUD is medication-assisted treatment, in combination with behavioral therapy. Medications for opioid use disorder have been shown to improv…
Effects of Buprenorphine Dose and Therapeutic Engagement on Illicit Opiate Use in Opioid Use Disorder Treatment Trials
The impact of agonist dose and of physician, staff and patient engagement on treatment have not been evaluated together in an analysis of treatment for opioid use disorder. Our hypotheses were that greater agonist dose and therapeutic engagement would be associated with reduced illicit opiate use in a time-dependent manner. Publicly-available treatment data from six buprenorphine efficacy and safety trials from the Federally-supported Clinical Tr…
Covid-19 vaccine effectiveness against general Sars-CoV-2 infection from the omicron variant
We aim to estimate the effectiveness of 2-dose and 3-dose mRNA vaccination (BNT162b2 and mRNA-1273) against general Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection (asymptomatic or symptomatic) caused by the omicron BA.1 variant. This propensity-score matched retrospective cohort study takes place in a large public university undergoing weekly Coronavirus Disease 2019 (Covid-19) testing in South Carolina, USA. The populatio…
Bayesian Machine Learning Tools for Alcohol Use Disorder Research
Alcohol use disorder (AUD) research faces significant challenges in capturing individual heterogeneity and complex temporal patterns in drinking behaviors. Standard statistical methods fail to account for within-person variability and between-person differences, while existing machine learning algorithms are not designed for hierarchical, longitudinal data structures common in AUD research. We developed a comprehensive R package implementing 30 B…
Medicine (4 works) · Internal Medicine (3 works) · Substance Abuse Treatment and Outcomes (3 works) · Buprenorphine (2 works) · Disease (2 works) · Environmental health (2 works) · Nursing (2 works) · Opioid (2 works) · Opioid use disorder (2 works) · Opioid Use Disorder Treatment (2 works)