Clint Pecenka
Biographic Data
| ID | 7784505 |
|---|---|
| NAME | Clint Pecenka |
| GIVEN NAMES | Clint |
| FAMILY NAME | Pecenka |
| SIGNATURE | PECENKA C |
| AFFILIATIONS | Program for Appropriate Technology in Health |
| ORCID | 0000-0002-2284-3557 |
| VERIFIED | Yes |
| TOTAL WORKS | 15 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 15 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2021 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Antibiotic use in respiratory syncytial virus-positive children under two years
Introduction Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in children, often leading to hospitalization in infants and vulnerable children. In low-resource settings where routine RSV diagnostics are unavailable, the overlap between clinical symptoms of RSV and those of bacterial pneumonia leads to unnecessary antibiotic use and contributes to the development of antimicrobial resistance. We conducted thi…
Impact and cost-effectiveness of two interventions to prevent paediatric respiratory syncytial virus disease in Cameroon
Background: Preventive interventions for respiratory syncytial virus (RSV) disease are emerging and have been approved for support by Gavi, the Vaccine Alliance. However, their cost-effectiveness is under-researched in low- and middle-income countries, where RSV burden remains the highest. We modelled the potential impact and cost-effectiveness of two interventions for the prevention of RSV in young children in Cameroon, a Gavi-eligible country w…
The economic burden of respiratory syncytial virus and other acute respiratory infections among children <2 years old seeking care at a tertiary facility in Accra, Ghana
Background: The global burden of the respiratory syncytial virus (RSV) disproportionately affects low- and middle-income countries (LMICs). The World Health Organization's Strategic Advisory Group of Experts on Immunisation recently recommended the global implementation of emerging RSV immunisation strategies to protect infants. Cost of illness data are needed to estimate the economic burden of RSV and evaluate the introduction of these immunisat…
Estimating the economic burden of respiratory syncytial virus infection among children <2 years old seeking care in North-West Nigeria
Background: Respiratory syncytial virus (RSV) disease burden is highest in low- and middle-income countries; yet data for costs of RSV-related illness in these settings are scarce. We estimated RSV costs of illness to inform decision-making for RSV preventive strategies in Nigeria. Methods: This prospective study assessed the costs of care per episode of (severe) acute respiratory infection during one RSV season (April to November 2023). Children…
Cost-effectiveness of introducing a maternal vaccine or long-acting monoclonal antibody to prevent infant respiratory syncytial virus disease in Nepal
Background: The World Health Organization recommends two passive immunisation strategies to prevent respiratory syncytial virus (RSV) disease in young infants. Both are being introduced in high-income settings, but their affordability and cost-effectiveness have not been evaluated in many low- and middle-income countries. Preliminary estimates of cost-effectiveness are needed to guide immunisation policy and planning in Nepal. Methods: We estimat…
Estimating the economic burden of respiratory syncytial virus infection among children <2 years old receiving care in Maputo, Mozambique
Background: Data on costs of respiratory syncytial virus (RSV) in low- and lower-middle-income countries are urgently needed to inform the introduction of recently developed vaccines. We estimated the costs of lower respiratory tract infections associated with RSV infection in Mozambique. Methods: We conducted a prospective cohort study to assess household and societal costs of RSV infection in children <2 years old who sought care in a referral …
Assessing the cost of illness of RSV and non-RSV acute respiratory infections in Nepali children
Background: Low- and middle-income countries (LMICs) bear the greatest burden of the global respiratory syncytial virus (RSV) morbidity and mortality, but lack cost data to evaluate the health-economic impact of RSV burden on families, the healthcare system, and society. This prospective observational study was performed by the RSV GOLD III - Health Economic Research Group and estimated the costs associated with RSV illness in Nepal. Methods: We …
Maternal vaccine delivery costs in South Asian settings
MI delivery costs in LMICs are little known and this study contributes to filling this gap. These cost projections can equip countries to make informed introduction decisions as they evaluate the affordability and sustainability of MI programs in respective countries
Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
This study shows the direct economic impact of acute severe RSV infection on the public health system in Argentina. The estimates obtained from this study could be used to inform cost-effectiveness analyses of new preventive RSV interventions being developed
The cost of care for children hospitalized with respiratory syncytial virus (RSV) associated lower respiratory infection in Kenya
RSV-associated disease among young children leads to a substantial economic burden to both families and the health system in Kenya. This burden may differ between Counties in Kenya and similar multi-site studies are advised to support cost-effectiveness analyses
Cost of introducing and delivering malaria vaccine (RTS,S/AS01 E ) in areas of seasonal malaria transmission, Mali and Burkina Faso
BACKGROUND: malaria transmission and suggests countries consider seasonal vaccination in areas with highly seasonal malaria. Seasonal vaccination is uncommon and may require adaptations with potential cost consequences. This study prospectively estimates cost of seasonal malaria vaccine delivery in Mali and Burkina Faso. METHODS: Three scenarios for seasonal vaccine delivery are costed (1) mass campaign only, (2) routine Expanded Programme on Imm…
Rotavirus vaccine product switch in Ghana
Ghana introduced rotavirus vaccine (ROTARIX 1-dose presentation) into the routine national immunization program in 2012 and switched to a different product (ROTAVAC 5-dose presentation) in 2020. ROTAVAC has a lower price per dose (US$0.85 versus US$2.15 for ROTARIX) and smaller cold chain footprint but requires more doses per regimen (three versus two). This study estimates the supply chain and service delivery costs associated with each product,…
Estimating the cost of illness of acute Japanese encephalitis and sequelae care in Vietnam and Laos
Background Japanese encephalitis (JE) is a leading cause of acute encephalitis syndrome and resulting neurological disability in Asia and the Western Pacific. This study aims to estimate the cost of acute care, initial rehabilitation and sequelae care, in Vietnam and Laos. Methodology We conducted a cross-sectional retrospective study using a micro-costing approach from the health system and household perspectives. Out-of-pocket direct medical an…
Optimizing next-generation RSV prevention in Mali
Respiratory syncytial virus (RSV) is the most common cause of early childhood lower respiratory tract infection (LRTI) in low- and middle-income countries (LMICs). Maternal vaccines, birth-dose extended half-life monoclonal antibodies (mAbs), and pediatric vaccines are under development for prevention of respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) in young children. We analyzed the health and economic impact of RSV …
Pneumococcal conjugate vaccination in The Gambia
INTRODUCTION: . Many low-income countries, however, will soon reach an economic status leading to transition from Gavi, the Vaccine Alliance vaccine funding support and then face increased expenditure to continue PCV programmes. Evaluating the cost-effectiveness of PCV in low-income countries will inform such country decisions. METHODS: We used empiric data on the costs of vaccine delivery and pneumococcal disease and PCV programme impact on dise…
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Pneumococcal conjugate vaccination in The Gambia
INTRODUCTION: . Many low-income countries, however, will soon reach an economic status leading to transition from Gavi, the Vaccine Alliance vaccine funding support and then face increased expenditure to continue PCV programmes. Evaluating the cost-effectiveness of PCV in low-income countries will inform such country decisions. METHODS: We used empiric data on the costs of vaccine delivery and pneumococcal disease and PCV programme impact on dise…
Cost of introducing and delivering malaria vaccine (RTS,S/AS01 E ) in areas of seasonal malaria transmission, Mali and Burkina Faso
BACKGROUND: malaria transmission and suggests countries consider seasonal vaccination in areas with highly seasonal malaria. Seasonal vaccination is uncommon and may require adaptations with potential cost consequences. This study prospectively estimates cost of seasonal malaria vaccine delivery in Mali and Burkina Faso. METHODS: Three scenarios for seasonal vaccine delivery are costed (1) mass campaign only, (2) routine Expanded Programme on Imm…
Rotavirus vaccine product switch in Ghana
Ghana introduced rotavirus vaccine (ROTARIX 1-dose presentation) into the routine national immunization program in 2012 and switched to a different product (ROTAVAC 5-dose presentation) in 2020. ROTAVAC has a lower price per dose (US$0.85 versus US$2.15 for ROTARIX) and smaller cold chain footprint but requires more doses per regimen (three versus two). This study estimates the supply chain and service delivery costs associated with each product,…
Estimating the cost of illness of acute Japanese encephalitis and sequelae care in Vietnam and Laos
Background Japanese encephalitis (JE) is a leading cause of acute encephalitis syndrome and resulting neurological disability in Asia and the Western Pacific. This study aims to estimate the cost of acute care, initial rehabilitation and sequelae care, in Vietnam and Laos. Methodology We conducted a cross-sectional retrospective study using a micro-costing approach from the health system and household perspectives. Out-of-pocket direct medical an…
Optimizing next-generation RSV prevention in Mali
Respiratory syncytial virus (RSV) is the most common cause of early childhood lower respiratory tract infection (LRTI) in low- and middle-income countries (LMICs). Maternal vaccines, birth-dose extended half-life monoclonal antibodies (mAbs), and pediatric vaccines are under development for prevention of respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) in young children. We analyzed the health and economic impact of RSV …
Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
This study shows the direct economic impact of acute severe RSV infection on the public health system in Argentina. The estimates obtained from this study could be used to inform cost-effectiveness analyses of new preventive RSV interventions being developed
The cost of care for children hospitalized with respiratory syncytial virus (RSV) associated lower respiratory infection in Kenya
RSV-associated disease among young children leads to a substantial economic burden to both families and the health system in Kenya. This burden may differ between Counties in Kenya and similar multi-site studies are advised to support cost-effectiveness analyses
Estimating the economic burden of respiratory syncytial virus infection among children <2 years old seeking care in North-West Nigeria
Background: Respiratory syncytial virus (RSV) disease burden is highest in low- and middle-income countries; yet data for costs of RSV-related illness in these settings are scarce. We estimated RSV costs of illness to inform decision-making for RSV preventive strategies in Nigeria. Methods: This prospective study assessed the costs of care per episode of (severe) acute respiratory infection during one RSV season (April to November 2023). Children…
Cost-effectiveness of introducing a maternal vaccine or long-acting monoclonal antibody to prevent infant respiratory syncytial virus disease in Nepal
Background: The World Health Organization recommends two passive immunisation strategies to prevent respiratory syncytial virus (RSV) disease in young infants. Both are being introduced in high-income settings, but their affordability and cost-effectiveness have not been evaluated in many low- and middle-income countries. Preliminary estimates of cost-effectiveness are needed to guide immunisation policy and planning in Nepal. Methods: We estimat…
Estimating the economic burden of respiratory syncytial virus infection among children <2 years old receiving care in Maputo, Mozambique
Background: Data on costs of respiratory syncytial virus (RSV) in low- and lower-middle-income countries are urgently needed to inform the introduction of recently developed vaccines. We estimated the costs of lower respiratory tract infections associated with RSV infection in Mozambique. Methods: We conducted a prospective cohort study to assess household and societal costs of RSV infection in children <2 years old who sought care in a referral …
Assessing the cost of illness of RSV and non-RSV acute respiratory infections in Nepali children
Background: Low- and middle-income countries (LMICs) bear the greatest burden of the global respiratory syncytial virus (RSV) morbidity and mortality, but lack cost data to evaluate the health-economic impact of RSV burden on families, the healthcare system, and society. This prospective observational study was performed by the RSV GOLD III - Health Economic Research Group and estimated the costs associated with RSV illness in Nepal. Methods: We …
Maternal vaccine delivery costs in South Asian settings
MI delivery costs in LMICs are little known and this study contributes to filling this gap. These cost projections can equip countries to make informed introduction decisions as they evaluate the affordability and sustainability of MI programs in respective countries
Antibiotic use in respiratory syncytial virus-positive children under two years
Introduction Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in children, often leading to hospitalization in infants and vulnerable children. In low-resource settings where routine RSV diagnostics are unavailable, the overlap between clinical symptoms of RSV and those of bacterial pneumonia leads to unnecessary antibiotic use and contributes to the development of antimicrobial resistance. We conducted thi…
Impact and cost-effectiveness of two interventions to prevent paediatric respiratory syncytial virus disease in Cameroon
Background: Preventive interventions for respiratory syncytial virus (RSV) disease are emerging and have been approved for support by Gavi, the Vaccine Alliance. However, their cost-effectiveness is under-researched in low- and middle-income countries, where RSV burden remains the highest. We modelled the potential impact and cost-effectiveness of two interventions for the prevention of RSV in young children in Cameroon, a Gavi-eligible country w…
The economic burden of respiratory syncytial virus and other acute respiratory infections among children <2 years old seeking care at a tertiary facility in Accra, Ghana
Background: The global burden of the respiratory syncytial virus (RSV) disproportionately affects low- and middle-income countries (LMICs). The World Health Organization's Strategic Advisory Group of Experts on Immunisation recently recommended the global implementation of emerging RSV immunisation strategies to protect infants. Cost of illness data are needed to estimate the economic burden of RSV and evaluate the introduction of these immunisat…
Respiratory viral infections research (11 works) · Respiratory system (9 works) · Medicine (8 works) · Pediatrics (7 works) · Pneumonia and Respiratory Infections (7 works) · Immunology (5 works) · Internal Medicine (5 works) · Virus (5 works) · Cost effectiveness (4 works) · Psychological intervention (4 works)