Sheela Godbole
Dados Biográficos
| ID | 7785961 |
|---|---|
| NOME | Sheela Godbole |
| PRENOMES | Sheela |
| SOBRENOME | Godbole |
| ASSINATURA | GODBOLE S |
| AFILIAÇÕES | National AIDS Research Institute |
| ORCID | 0000-0001-6537-9064 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 12 |
| TOTAL DE CITAÇÕES | 2 |
| TOTAL COMO AUTOR | 12 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1999 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 1 |
Programmatic mapping and population size estimation of key population in India
India has the world’s second-largest HIV burden. Key populations of female sex workers (FSW), men who have sex with men (MSM), hijra/transgender (H/TG) people, and people who inject drugs (PWID), are disproportionately affected by the HIV epidemic. A community-led programmatic mapping and population size estimation (PMPSE) was carried out in 651 districts of 32 States and Union Territories of India. The goal was to identify the hotspots, network …
Facilitators and barriers to the uptake of Covid-19 vaccine precaution dose among adult population
Introduction: India launched the COVID-19 vaccination drive on 16th January 2021 by vaccinating the adult population above 18 years of age. This was followed by the introduction of an additional precaution dose. As on 18th October 2022, 1,02,66,96,808 (1.02 Billion) first dose and 94, 95, 39,516 (949 Million) second doses of COVID-19 vaccine were administered. However, when compared to the uptake of the primary doses, the precaution dose uptake l…
Projected impact of fast-tracking of anti-retroviral treatment coverage on vertical transmission of HIV in India
One of the five high-level goals under Phase V of the National AIDS and STD Control Programme (NACP) of the Government of India is the elimination of vertical transmission of HIV. In this paper, we estimate the potential impact of maintaining and enhancing the anti-retroviral treatment under the NACP in terms of averting new infections and vertical transmission rates vis-à-vis no intervention scenario. We used India’s HIV Estimates 2022 models to…
Augmenting progress on the elimination of vertical transmissions of HIV in India
The government of India has adopted the elimination of vertical transmission of HIV as one of the five high-level goals under phase V of the National AIDS and STD Control Programme (NACP). In this paper, we present the data from HIV estimations 2021 for India and select States detailing the progress as well as the attributable causes for vertical transmissions. The NACP spearheads work on mathematical modelling to estimate HIV burden based on the…
Pregnancy rates and clinical outcomes among women living with HIV enrolled in HPTN 052
HPTN 052 was a multi-country clinical trial of cART for preventing heterosexual HIV-1 transmission. The study allowed participation of pregnant women and provided access to cART and contraceptives. We explored associations between pregnancy and clinical measures of HIV disease stage and progression. Of 869 women followed for 5.70 (SD = 1.62) years, 94.7% were married/cohabitating, 96% initiated cART, and 76.3% had >2 past pregnancies. Of 337 wome…
Antiretroviral Therapy for the Prevention of HIV-1 Transmission
BACKGROUND: An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to all patients with HIV-1 infection (index participants). The study included more than 5 years of follow-up to assess the durability of such therapy for …
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection
Risk reduction and perceived collective efficacy and community support among female sex workers in Tamil Nadu and Maharashtra, India
BACKGROUND: Empowering sex workers to mobilise and influence the structural context that obstructs risk reduction efforts is now seen an essential component of successful HIV prevention programmes. However, success depends on local programme environments and history. METHODS: The authors analysed data from the Integrated Behavioural and Biological Assessment Round I cross-sectional survey among female sex workers in Tamil Nadu and Maharashtra. Th…
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
BACKGROUND: Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. METHODS: In nine countries, we enrolled 1763 couples in which one partner was HIV-1-positive and the other was HIV-1-negative; 54% of the subjects were from Africa, and 50% of infected partners were men. HIV-1-infected subjects with CD4 counts between 350 and 550 cells per cubic m…
Impact of targeted interventions on heterosexual transmission of HIV in India
Targeted interventions are associated with HIV prevalence decline
Stigmatizing attitudes and low levels of knowledge but high willingness to participate in HIV management
There is a high willingness to participate in HIV management among community-based pharmacies but there is a tremendous need for training on HIV therapies. Furthermore, stigmatizing attitudes towards HIV-infected persons persist and interventions to reduce stigma are needed, particularly among those that stock ARVs
Prevalence of Haemoglobinopathies Among Different Populations of Jabalpur, Madhya Pradesh
Present study has been carried out on the prevalence of haemoglobinopathies among various population groups viz., Scheduled Castes. Scheduled Tribes, Other Back-ward Classes and General category of Jabalpur. Madhya Pradesh The analysis of data revealed that highest incidence of haemoglobinopathies (14.2%) was found in Scheduled Tribes. This may be due to endogamy among the tribal population. Imparting health education is seeded as a preventive me…
Risk reduction and perceived collective efficacy and community support among female sex workers in Tamil Nadu and Maharashtra, India
BACKGROUND: Empowering sex workers to mobilise and influence the structural context that obstructs risk reduction efforts is now seen an essential component of successful HIV prevention programmes. However, success depends on local programme environments and history. METHODS: The authors analysed data from the Integrated Behavioural and Biological Assessment Round I cross-sectional survey among female sex workers in Tamil Nadu and Maharashtra. Th…
Prevalence of Haemoglobinopathies Among Different Populations of Jabalpur, Madhya Pradesh
Present study has been carried out on the prevalence of haemoglobinopathies among various population groups viz., Scheduled Castes. Scheduled Tribes, Other Back-ward Classes and General category of Jabalpur. Madhya Pradesh The analysis of data revealed that highest incidence of haemoglobinopathies (14.2%) was found in Scheduled Tribes. This may be due to endogamy among the tribal population. Imparting health education is seeded as a preventive me…
Stigmatizing attitudes and low levels of knowledge but high willingness to participate in HIV management
There is a high willingness to participate in HIV management among community-based pharmacies but there is a tremendous need for training on HIV therapies. Furthermore, stigmatizing attitudes towards HIV-infected persons persist and interventions to reduce stigma are needed, particularly among those that stock ARVs
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
BACKGROUND: Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. METHODS: In nine countries, we enrolled 1763 couples in which one partner was HIV-1-positive and the other was HIV-1-negative; 54% of the subjects were from Africa, and 50% of infected partners were men. HIV-1-infected subjects with CD4 counts between 350 and 550 cells per cubic m…
Impact of targeted interventions on heterosexual transmission of HIV in India
Targeted interventions are associated with HIV prevalence decline
Risk reduction and perceived collective efficacy and community support among female sex workers in Tamil Nadu and Maharashtra, India
BACKGROUND: Empowering sex workers to mobilise and influence the structural context that obstructs risk reduction efforts is now seen an essential component of successful HIV prevention programmes. However, success depends on local programme environments and history. METHODS: The authors analysed data from the Integrated Behavioural and Biological Assessment Round I cross-sectional survey among female sex workers in Tamil Nadu and Maharashtra. Th…
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection
Antiretroviral Therapy for the Prevention of HIV-1 Transmission
BACKGROUND: An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to all patients with HIV-1 infection (index participants). The study included more than 5 years of follow-up to assess the durability of such therapy for …
Augmenting progress on the elimination of vertical transmissions of HIV in India
The government of India has adopted the elimination of vertical transmission of HIV as one of the five high-level goals under phase V of the National AIDS and STD Control Programme (NACP). In this paper, we present the data from HIV estimations 2021 for India and select States detailing the progress as well as the attributable causes for vertical transmissions. The NACP spearheads work on mathematical modelling to estimate HIV burden based on the…
Pregnancy rates and clinical outcomes among women living with HIV enrolled in HPTN 052
HPTN 052 was a multi-country clinical trial of cART for preventing heterosexual HIV-1 transmission. The study allowed participation of pregnant women and provided access to cART and contraceptives. We explored associations between pregnancy and clinical measures of HIV disease stage and progression. Of 869 women followed for 5.70 (SD = 1.62) years, 94.7% were married/cohabitating, 96% initiated cART, and 76.3% had >2 past pregnancies. Of 337 wome…
Facilitators and barriers to the uptake of Covid-19 vaccine precaution dose among adult population
Introduction: India launched the COVID-19 vaccination drive on 16th January 2021 by vaccinating the adult population above 18 years of age. This was followed by the introduction of an additional precaution dose. As on 18th October 2022, 1,02,66,96,808 (1.02 Billion) first dose and 94, 95, 39,516 (949 Million) second doses of COVID-19 vaccine were administered. However, when compared to the uptake of the primary doses, the precaution dose uptake l…
Projected impact of fast-tracking of anti-retroviral treatment coverage on vertical transmission of HIV in India
One of the five high-level goals under Phase V of the National AIDS and STD Control Programme (NACP) of the Government of India is the elimination of vertical transmission of HIV. In this paper, we estimate the potential impact of maintaining and enhancing the anti-retroviral treatment under the NACP in terms of averting new infections and vertical transmission rates vis-à-vis no intervention scenario. We used India’s HIV Estimates 2022 models to…
Programmatic mapping and population size estimation of key population in India
India has the world’s second-largest HIV burden. Key populations of female sex workers (FSW), men who have sex with men (MSM), hijra/transgender (H/TG) people, and people who inject drugs (PWID), are disproportionately affected by the HIV epidemic. A community-led programmatic mapping and population size estimation (PMPSE) was carried out in 651 districts of 32 States and Union Territories of India. The goal was to identify the hotspots, network …
Medicine (12 obras) · HIV/AIDS Research and Interventions (10 obras) · Environmental health (6 obras) · HIV, Drug Use, Sexual Risk (6 obras) · Demography (5 obras) · Viral load (5 obras) · Antiretroviral therapy (4 obras) · HIV Research and Treatment (4 obras) · Human immunodeficiency virus (HIV) (4 obras) · Virology (4 obras)