Bruce D Naliboff
Biographic Data
| ID | 7832585 |
|---|---|
| NAME | Bruce D Naliboff |
| GIVEN NAMES | Bruce D |
| FAMILY NAME | Naliboff |
| SIGNATURE | NALIBOFF B D |
| AFFILIATIONS | University of California, Los Angeles |
| ORCID | 0000-0003-0959-8670 |
| VERIFIED | Yes |
| TOTAL WORKS | 11 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 11 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1991 |
| LATEST PUBLICATION YEAR | 2014 |
| H-INDEX | 0 |
Gastrointestinal specific anxiety in irritable bowel syndrome
OBJECTIVE: The visceral sensitivity index (VSI) is a useful self-report measure of the gastrointestinal symptom-specific anxiety (GSA) of patients with irritable bowel syndrome (IBS). Previous research has shown that worsening GSA in IBS patients is related to the severity of GI symptoms, suggesting that GSA is an important endpoint for intervention. However, there is currently no Japanese version of the VSI. We therefore translated the VSI into …
Early Adverse Life Events and Resting State Neural Networks in Patients With Chronic Abdominal Pain
BACKGROUND: Early adverse life events (EALs) and sex have been identified as vulnerability factors for the development of several stress-sensitive disorders, including irritable bowel syndrome (IBS). We aimed to identify disease and sex-based differences in resting state (RS) connectivity associated with EALs in individuals with IBS. METHOD: A history of EALs before age 18 years was assessed using the early trauma inventory. RS functional magneti…
Human anterior and posterior hippocampus respond distinctly to state and trait anxiety
We examined whether anterior and posterior hippocampal subregions in humans show distinct relationships to state and trait anxiety. In rodents, the ventral (but not dorsal) hippocampus is critically involved in contextual anxiety, whereas dorsal hippocampus is affected by chronic stress and genetically bred trait anxiety. These studies suggest that state forms of anxiety may be more associated with anterior (ventral in rodents) hippocampus, where…
Increased Acoustic Startle Responses in IBS Patients During Abdominal and Nonabdominal Threat
Background and Aims: Visceral hypersensitivity and symptom severity in Irritable Bowel Syndrome (IBS) are both exacerbated by stress. The eye-blink startle response represents a noninvasive measure of central defensive responding. Evidence for central hyperexcitability was studied in IBS patients by examining potentiation of the startle reflex to a nociceptive threat. Methods: Acoustic startle responses were examined in female IBS patients (n = 4…
The Central Role of Gastrointestinal-Specific Anxiety in Irritable Bowel Syndrome
OBJECTIVES: The Visceral Sensitivity Index (VSI) was developed as the first instrument to assess gastrointestinal-specific anxiety, the cognitive, affective, and behavioral response to fear of gastrointestinal sensations, symptoms, and the context in which these visceral sensations and symptoms occur. The purpose of the current study was to a) replicate the previously reported psychometric properties of the VSI, b) assess the known-groups and con…
The Effect of Life Stress on Symptoms of Heartburn
OBJECTIVE: Psychosocial stressors have been associated with exacerbations of symptoms in functional and inflammatory disorders of the gastrointestinal tract. The present longitudinal study tests the general hypothesis that life stressors can exacerbate symptoms in patients with chronic heartburn. METHODS: Sixty subjects with current heartburn symptoms were recruited by community advertisement and assessed for presence of stressful life events ret…
Rome Ii
Cognitive-Behavioral Treatment of Irritable Bowel Syndrome
UCLA/CURE Neuroenteric Disease Program Psychophysiology Research W-151 West LA VAMC 11301 Wilshire Blvd. Los Angeles, CA 90073 Email: [email protected]
Cerebral Activation in Patients With Irritable Bowel Syndrome and Control Subjects During Rectosigmoid Stimulation
OBJECTIVE: Patients with irritable bowel syndrome (IBS) show evidence of altered perceptual responses to visceral stimuli, consistent with altered processing of visceral afferent information by the brain. In the current study, brain responses to anticipated and delivered rectal balloon distension were assessed. METHODS: Changes in regional cerebral blood flow were measured using H2(15)O-water positron emission tomography in 12 nonconstipated IBS …
Cardiovascular and Immune Responses to Acute Psychological Stress in Young and Old Women
OBJECTIVE: To describe the relationships between cardiovascular and natural killer (NK) cell number changes on acute psychological stress in women. METHOD: Data from eight different studies were analyzed. A total of 128 healthy female subjects, 85 younger (18-45 years) and 43 older (49-87 years), had been subjected to a speech stressor (N = 80) or a mental effort stressor (N = 48), mental arithmetic, or the Stroop test. Correlations between chang…
Immunological changes in young and old adults during brief laboratory stress
Few data are available on the response of the human immune system to acute psychological stressors under controlled laboratory conditions. Young female subjects (21-41 years) showed increases in natural killer (NK) cell activity, and in the numbers of circulating CD8 suppressor/cytotoxic T cells, and natural killer lymphocytes following a brief (12 minute) stressful mental arithmetic examination. Older female subjects (65-85 years) failed to show…
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Immunological changes in young and old adults during brief laboratory stress
Few data are available on the response of the human immune system to acute psychological stressors under controlled laboratory conditions. Young female subjects (21-41 years) showed increases in natural killer (NK) cell activity, and in the numbers of circulating CD8 suppressor/cytotoxic T cells, and natural killer lymphocytes following a brief (12 minute) stressful mental arithmetic examination. Older female subjects (65-85 years) failed to show…
Cardiovascular and Immune Responses to Acute Psychological Stress in Young and Old Women
OBJECTIVE: To describe the relationships between cardiovascular and natural killer (NK) cell number changes on acute psychological stress in women. METHOD: Data from eight different studies were analyzed. A total of 128 healthy female subjects, 85 younger (18-45 years) and 43 older (49-87 years), had been subjected to a speech stressor (N = 80) or a mental effort stressor (N = 48), mental arithmetic, or the Stroop test. Correlations between chang…
Cerebral Activation in Patients With Irritable Bowel Syndrome and Control Subjects During Rectosigmoid Stimulation
OBJECTIVE: Patients with irritable bowel syndrome (IBS) show evidence of altered perceptual responses to visceral stimuli, consistent with altered processing of visceral afferent information by the brain. In the current study, brain responses to anticipated and delivered rectal balloon distension were assessed. METHODS: Changes in regional cerebral blood flow were measured using H2(15)O-water positron emission tomography in 12 nonconstipated IBS …
Rome Ii
Cognitive-Behavioral Treatment of Irritable Bowel Syndrome
UCLA/CURE Neuroenteric Disease Program Psychophysiology Research W-151 West LA VAMC 11301 Wilshire Blvd. Los Angeles, CA 90073 Email: [email protected]
The Effect of Life Stress on Symptoms of Heartburn
OBJECTIVE: Psychosocial stressors have been associated with exacerbations of symptoms in functional and inflammatory disorders of the gastrointestinal tract. The present longitudinal study tests the general hypothesis that life stressors can exacerbate symptoms in patients with chronic heartburn. METHODS: Sixty subjects with current heartburn symptoms were recruited by community advertisement and assessed for presence of stressful life events ret…
The Central Role of Gastrointestinal-Specific Anxiety in Irritable Bowel Syndrome
OBJECTIVES: The Visceral Sensitivity Index (VSI) was developed as the first instrument to assess gastrointestinal-specific anxiety, the cognitive, affective, and behavioral response to fear of gastrointestinal sensations, symptoms, and the context in which these visceral sensations and symptoms occur. The purpose of the current study was to a) replicate the previously reported psychometric properties of the VSI, b) assess the known-groups and con…
Increased Acoustic Startle Responses in IBS Patients During Abdominal and Nonabdominal Threat
Background and Aims: Visceral hypersensitivity and symptom severity in Irritable Bowel Syndrome (IBS) are both exacerbated by stress. The eye-blink startle response represents a noninvasive measure of central defensive responding. Evidence for central hyperexcitability was studied in IBS patients by examining potentiation of the startle reflex to a nociceptive threat. Methods: Acoustic startle responses were examined in female IBS patients (n = 4…
Human anterior and posterior hippocampus respond distinctly to state and trait anxiety
We examined whether anterior and posterior hippocampal subregions in humans show distinct relationships to state and trait anxiety. In rodents, the ventral (but not dorsal) hippocampus is critically involved in contextual anxiety, whereas dorsal hippocampus is affected by chronic stress and genetically bred trait anxiety. These studies suggest that state forms of anxiety may be more associated with anterior (ventral in rodents) hippocampus, where…
Gastrointestinal specific anxiety in irritable bowel syndrome
OBJECTIVE: The visceral sensitivity index (VSI) is a useful self-report measure of the gastrointestinal symptom-specific anxiety (GSA) of patients with irritable bowel syndrome (IBS). Previous research has shown that worsening GSA in IBS patients is related to the severity of GI symptoms, suggesting that GSA is an important endpoint for intervention. However, there is currently no Japanese version of the VSI. We therefore translated the VSI into …
Early Adverse Life Events and Resting State Neural Networks in Patients With Chronic Abdominal Pain
BACKGROUND: Early adverse life events (EALs) and sex have been identified as vulnerability factors for the development of several stress-sensitive disorders, including irritable bowel syndrome (IBS). We aimed to identify disease and sex-based differences in resting state (RS) connectivity associated with EALs in individuals with IBS. METHOD: A history of EALs before age 18 years was assessed using the early trauma inventory. RS functional magneti…
Medicine (9 works) · Gastrointestinal motility and disorders (8 works) · Irritable bowel syndrome (7 works) · Psychology (7 works) · Internal Medicine (6 works) · Psychiatry (6 works) · Anxiety (5 works) · Internal Medicine (5 works) · Neuroscience (5 works) · Clinical Psychology (3 works)